Clinical trials: Surgical Anastomosis
Pouchitis, Irritable Pouch Syndrome
Efficacy of Liraglutide Therapy in Patients With IPAA
Patients with an ileal pouch-anal anastomosis(IPAA; pouch) due to refractory inflammatory bowel disease and increased bowel frequency in the absence of significant pouch inflammation will be randomized to liraglutide or placebo…
- Trial name
- NCT04763564
- Testing
- Liraglutide Pen Injector
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of North Carolina, Chapel Hill
Rectal Cancer
ReAL Trial (Rectal Anastomotic seaL)
The problem of anastomotic leak is particularly relevant in rectal surgery. Many risk factors have been recognized in the onset of this complication.
- Trial name
- ReAL (NCT03941938)
- Testing
- Cyanoacrylate reinforcement, No reinforcement
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Intestinal Anastomosis
Emergency Intestinal Anastmosis
The goal of this clinical trial is to compare the outcomes of emergency intestinal anastomosis after stapled and handsewn anastmosis.
- Trial name
- NCT07321743
- Testing
- emergency intestinal anastmosis surgery
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Colorectal Cancer
Indicators of Anastomotic Leak After Colorectal Surgery
We reviewed the patient underwent colorectal surgery with anastomosis and identified patients with anastomotic leak. Then we started to figure out what blood investigation could be related to anastomotic leak.
- Trial name
- NCT06156358
- Testing
- No intervention
- Volunteers
- 441 people
- Sponsor
- King Abdulaziz University
Prostate Cancer
Global Performance Evaluation of the AMS CONTINUUM™ Device
1. To evaluate Device performance in providing mucosa to mucosa apposition to facilitate sustainable vesico-urethral anastomosis during a radical prostatectomy procedure. 2.
- Trial name
- NCT01083199
- Testing
- CONTINUUM™
- Where
- 2 sites in Greece, Spain
- Volunteers
- 10 people
- Sponsor
- American Medical Systems
Bronchus Anastomosis, Bronchus Stump
Hyperspectral Imaging in Thoracic Surgery
The aim of this study is to find out whether hyperspectral imaging enables bronchus stump and bronchus anastomosis oxygenation.
- Conditions
- Bronchus Anastomosis, Bronchus Stump, Tissue Oxygenation
- Trial name
- PILOT-Tx-HSI (NCT04784884)
- Testing
- HSI
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- LungenClinic Grosshansdorf
Anastomotic Leaks
Surgical Intuition in Anastomotic Leakage After Colorectal Surgery
The SURGUT study aims to assess how well a computer model predicts bowel leaks after surgery. It will also examine whether adding surgeons' intuition improves these predictions.
- Trial name
- SURGUT (NCT07888478)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,300 people
- Sponsor
- University Hospital, Basel, Switzerland
Urethral Stricture
Scandinavian Urethroplasty Study
A multicentre, prospective, randomized study comparing bulbar urethroplasty with excision and primary anastomosis or with an onlay grafting procedure using buccal mucosa.
- Trial name
- SUPS (NCT02321670)
- Testing
- End-to-end, Graft
- Where
- 4 sites in Finland, Norway and 1 more
- Volunteers
- 151 people
- Sponsor
- Oslo University Hospital
Colorectal Cancer, Surgery
Future of Colorectal Cancer Surgery
Colorectal cancer is the third most common cancer in the UK and Ireland, it is the second commonest cancer in both men and women.
- Trial name
- FOCCuS1 (NCT04220242)
- Testing
- Video recordings with analysis thereafter applied, Examination of microsections of tissue excised for the purposes of cancer resection, Cancer organoid development and testing
- Where
- Ireland
- Volunteers
- 250 people
- Sponsor
- Mater Misericordiae University Hospital
Rectal Cancer, Rectal Carcinoma
A Clinical Trial Comparing Staged Turnbull-Cutait Pull-through Anastomosis With Direct Anastomosis Plus Prophylactic Ileostomy in the Treatment of Low Rectal Cancer After Internal Sphincter Resection
This study targets patients undergoing ultra-low rectal cancer surgery, which requires internal sphincter resection for sphincter-saving procedures.
- Trial name
- STAR-TAR (NCT06662643)
- Testing
- Delayed transanal pull-through anastomosis, Direct Anastomosis Plus Prophylactic Ileostomy
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Zhongnan Hospital
Proximal Gastric Adenocarcinoma, Gastrectomy
Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract After Proximal Gastrectomy
The efficacy of three different reconstruction methods after proximal gastrectomy will be investigated in this study through a prospective, multicenter, randomized controlled trial.
- Conditions
- Proximal Gastric Adenocarcinoma, Gastrectomy, Anastomosis, Reflux Esophagitis
- Trial name
- NCT06062225
- Testing
- Kamikawa, STJI, SOFY
- Volunteers
- 180 people
- Sponsor
- Changzhi People's Hospital Affiliated to Changzhi Medical College
Obesity, Type2 Diabetes
Small Bowel Diversion
In an effort to replicate metabolic surgery's durable results in metabolic disease while minimizing its risks, two innovative methods has been created.
- Trial name
- NCT06374368
- Testing
- jejuno-ileal diversion, jejuno-colic diversion
- Where
- 2 sites in Czechia
- Volunteers
- 80 people
- Sponsor
- University of Ostrava
Gastric Cancer
Novel Esophago-Jejunal Anastomosis Method During Totally Laparoscopic Total Gastrectomy
Laparoscopic gastrectomy became a good option for early gastric cancer. Surgical trend is gradually changed to totally laparoscopic gastrectomy from laparoscopy-assisted gastrectomy requiring mini-laparotomy.
- Trial name
- NCT02330913
- Testing
- Intracorporeal esophagojejunostomy
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Keimyung University Dongsan Medical Center
Weight Loss
Long-term Follow up After SG vs RYGB vs OAGB
A prospective randomized clinical study of all morbidly obese patients undergoing SG, RYGB and OAGB, as primary bariatric procedures, was performed.
- Trial name
- NCT03467646
- Testing
- Sleeve Gastrectomy, Roux-en-Y gastric bypass, One-Anastomosis Gastric Bypass
- Volunteers
- 600 people
- Sponsor
- Hospital General Universitario Elche
Metabolic Syndrome, Severe Obesity
Endoscopic Conversion of Sleeve Gastrectomy to Single Anastomosis Sleeve-ileal Bypass (SASI) for Gastroesophageal Reflux (GERD), Primary and Secondary Non-responder.
The aim of this study is to determine the feasibility and effectiveness of endoscopic anastomosis of sleeve gastrectomy to ileum with a lumen apposing metal stent (LAMS) after a failed sleeve gastrectomy.
- Conditions
- Metabolic Syndrome, Severe Obesity, Reflux, Gastroesophageal, Bariatric Surgery
- Trial name
- NCT06757296
- Testing
- Endoscopic SASI
- Where
- 3 sites in Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore Health Services
Rectal Cancer Surgery, Anastomotic Leak Rectum
Impact of IMA Occlusion on Anastomotic Leakage
Rectal cancer is primarily treated with surgery, including low anterior resection or ultra-low anterior resection depending on tumor characteristics.
- Conditions
- Rectal Cancer Surgery, Anastomotic Leak Rectum, Inferior Mesenteric Artery
- Trial name
- NCT07656974
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Istanbul Saglik Bilimleri University
Rectal Cancer
Quality of Life of Patients After Rectal Cancer Resection .
Surgical treatment of cancer of the lower rectum by resection and coloanal anastomosis or abdominoperineal resection in both cases exposes the patient to significant functional digestive sequelae (anal incontinence or permanent…
- Trial name
- QRAAP (NCT07764120)
- Volunteers
- 22 people
- Sponsor
- University Hospital, Grenoble
Microvascular Anastomoses
U-clip Pilot Study in Plastic Surgery
This study will assess the nitinol U-clip as an alternative to conventional microsurgical suture for arterial anastomoses in free tissue transfer.
- Trial name
- NCT01218269
- Testing
- nitinol u-clip
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
Anastomotic Leak
Evaluation of Colonic Perfusion by Indocyanine Green Angiography During Colorectal Surgery
Despite advancements in technology and improved surgical techniques, the occurrence of anastomotic leakage (AL) after colorectal surgery remains between 4% and 30%.
- Trial name
- NCT06793280
- Testing
- intraoperative ICG angiography, No intraoperative ICG angiography
- Where
- Italy
- Volunteers
- 562 people
- Sponsor
- University of Roma La Sapienza
Distal Pancreatic Resections
Pancreatic Stump Closure After Distal Pancreatic Resection
The aim of this study is to investigate whether finnish binding pancreatico-jejunal anastomosis is feasible and prevents the risk for post operative pancreatic fistula after distal pancreeatectomy.
- Trial name
- NCT02113046
- Testing
- pancreatico-jejunal anastomosis, traditional anastomosis
- Where
- Finland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital