Clinical trials: Surgical Anastomosis
Ulcer Peptic
Ulcers Formation After Hand-Sewn vs Stapled Gastrojejunal Anastomosis In MGB.
We assume that the frequency of gastrojejunostomy ulcers after MGB-OAGB is associated with the peculiarities of the side-to-side gastrojejunostomy (GJS) formation, which is currently the "gold standard" for this procedure.
- Trial name
- ULTRA (NCT06077955)
- Testing
- Mini-gastric bypass with stapled anastomosis, Mini-gastric bypass with hand-sewn anastomosis
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Rectum Cancer, Faecal Incontinence
Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer.
The occurrence of colorectal cancer has increased from the third most common cancer in 2018 to the second most common cancer in 2023.
- Conditions
- Rectum Cancer, Faecal Incontinence, Faecal Incontinence with Faecal Urgency, Low Anterior Resection Syndrome
- Trial name
- NCT06601985
- Testing
- J-pouch anastomosis, direct anastomosis
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Shanghai 10th People's Hospital
Esophageal Cancer, Esophagus Cancer
Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer
A prospective, multi-centre, exploratory and observational one-arm study to evaluate preventive Endoluminal Vacuum Therapy(pEVT) to prevent anastomotic leakage after esophagectomy due to esophageal cancer.
- Conditions
- Esophageal Cancer, Esophagus Cancer, Anastomotic Leak
- Trial name
- ESPY (NCT06097078)
- Testing
- Eso-SPONGE®
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Aesculap AG
Colorectal Cancer
Indicators of Anastomotic Leak After Colorectal Surgery
We reviewed the patient underwent colorectal surgery with anastomosis and identified patients with anastomotic leak. Then we started to figure out what blood investigation could be related to anastomotic leak.
- Trial name
- NCT06156358
- Testing
- No intervention
- Volunteers
- 441 people
- Sponsor
- King Abdulaziz University
Morbid Obesity Requiring Bariatric Surgery
Midterm Follow up Outcomes of (SASJ) in Management of Morbid Obesity
Obesity is a critical health problem associated with an increased risk of cardiovascular disease, diabetes, and cancers, affecting both the quality of life and life expectancy .
- Trial name
- NCT07087535
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Colorectal Cancer
Evaluation of NiTi Shape Memory End-to-End Compression Anastomosis Ring (CAR) for Compression Anastomosis in Anterior Resection
The purpose of this study is to evaluate the safety and effectiveness of the NiTi CAR device in the creation of colorectal anastomosis
- Trial name
- NCT00468416
- Testing
- Compression Anastomosis Ring (CAR)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Gastric Cancer
Enterotomy Closure and Minimally Invasive Gastrectomy
All consecutive patients from January 2009 to december 2019 who underwent minimally invasive partial gastrectomy for gastric cancer at thirteen high volume institutions will be retrospective analysed to assess the better way to…
- Trial name
- NCT04901585
- Testing
- Totally intracorporeal distal gastrectomy
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Federico II University
Colorectal Cancer, Stoma - Ileostomy
SafeHeal Colovac Anastomosis Protection Device Evaluation Pivotal Study
Colorectal cancer is the third most common malignancy worldwide and the second most common in the US. It is the second leading cause of cancer death worldwide, with 1.8 million new cases and 862,000 deaths per year.
- Trial name
- SAFE-3CV (NCT07116668)
- Testing
- Colovac Anastomosis Protection Device placement following low anterior resection of colon cancer
- Where
- 18 sites in United States, Belgium and 2 more
- Volunteers
- 108 people
- Sponsor
- SafeHeal Inc
Colorectal Neoplasms, Colorectal Neoplasms Malignant
Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy
Robotic right hemicolectomy with intra-corporeal anastomosis may have better short-term recovery outcomes and decreased incidence of incisional hernia when compared to the laparoscopic actual standard of care, for similar safety…
- Conditions
- Colorectal Neoplasms, Colorectal Neoplasms Malignant, Colorectal Neoplasms, Benign, Colorectal Cancer
- Trial name
- PRORHEM (NCT06067620)
- Testing
- Robotic right hemicolectomy, Laparoscopic right hemicolectomy
- Volunteers
- 70 people
- Sponsor
- Jeremy Meyer
Education, Medical
Evaluation of Surgical Simulator for Practicing a Vascular Anastomosis
To determine if practicing an aorto-saphenous vein anastomosis on a low-fidelity surgical simulator allows trainees to produce a higher quality anastomosis in a shorter period of time, than a group that only learns by watching a…
- Trial name
- NCT00318279
- Testing
- Surgical simulator to practice vascular anastomosis
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dilated Gastric Tissue
Endolumenal Gastric Pouch and Gastrojejunal Anastomosis Reduction
Registry is designed to evaluate use of endolumenal tissue anchors for soft tissue approximation to repair a dilated gastric pouch and gastrojejunal anastomosis in post-Roux-En-Y gastric bypass patients presenting with weight…
- Trial name
- NCT01003743
- Testing
- endolumenal tissue approximation
- Where
- United States
- Sponsor
- USGI Medical
Lymphoedema of Leg, Lymphedema Arm
Added Value of Reconstructive Lymphatic Surgery to Usual Care in Lymphoedema
The primary objective of this research proposal is to investigate in patients with lymphoedema of the upper limb or lower limb (P) the added value of reconstructive lymphatic surgery (I) to the decongestive lymphatic therapy…
- Conditions
- Lymphoedema of Leg, Lymphedema Arm, Lymphedema
- Trial name
- SurLym (NCT05064176)
- Testing
- Usual care, Reconstructive lymphatic surgery
- Where
- 3 sites in Belgium
- Volunteers
- 180 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diverticulum, Colon, Colorectal Neoplasms
A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing device in routine clinical practice at 4-6 centers.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- NCT01880918
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- novoGI
Faecal Incontinence
A Study to Evaluate Topical Phenylephrine Gel in the Management of Faecal Incontinence
The aim of the study is to test the hypothesis that topical application of phenylephrine improves faecal continence and quality of life in subjects with passive faecal incontinence after ileo-anal pouch construction.
- Trial name
- NCT00420797
- Testing
- 10% Phenylephrine hydrochloride gel
- Where
- United Kingdom
- Sponsor
- S.L.A. Pharma AG
Marginal Ulcers
Ulcer Prevention Study in Post Gastric Bypass Patients
This research is to determine which medication, Zegerid (Omeprazole/Sodium Bicarbonate) or Pepcid AC (Famotidine), works best at reducing the chance that a patient will get an ulcer after gastric bypass surgery.
- Trial name
- NCT00557349
- Testing
- Omeprazole, Famotidine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Missouri-Columbia
Colorectal Cancer, Anastomosis
Safe Anastomosis Feasibility Study
A clinical trial to assess the efficacy, mechanism of action and safety of the Colovac+ Colorectal Anastomosis Protection Device in providing temporary protection of the anastomosis in subjects undergoing lower anterior resection…
- Trial name
- SAFE2019 (NCT05180565)
- Testing
- Colovac
- Where
- 7 sites in Belgium, France
- Volunteers
- 27 people
- Sponsor
- SafeHeal Inc
Liver Transplantation, Liver Transplant; Complications
EBD RCT Trial in Living Donor Liver Transplantation
This study was designed to demonstrate incidence of biliary complication rates after living donor liver transplantation according to the implantation of external biliary drainage throug duct-to-duct anastomosis site.
- Conditions
- Liver Transplantation, Liver Transplant; Complications, Bile Stricture, Bile Leakage From Biliary Anastomosis
- Trial name
- NCT04622540
- Testing
- External biliary drainage
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Hospital
Gastric Cancer, Anastomotic Leak
Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery
We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.
- Trial name
- NCT04490668
- Testing
- Human albumin
- Volunteers
- 1,049 people
- Sponsor
- Ruijin Hospital
Esophageal Cancer
Intrathoracic Esophagogastric Anastomosis After Robot Assisted Minimally Invasive Esophagectomy Using STRATAFIX
Determine the safety and efficacy of novel suture in esophageal anastomosis. Specific Aims: 1) Determine the safety of using STRATAFIX suture in esophagogastric anastomosis by measuring anastomotic leak rate; and 2) Determine…
- Trial name
- NCT02609425
- Testing
- Stratafix PGA Suture
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
End to End Anastomosis, Colorectal Anastomosis
End to End Anastomosis With Omega Suture Versus End to Anterior Rectal Wall In Colorectal Anastomosis in Sigmoid and Upper Rectal Cancer
The aim of this study is to compare end to end anastomosis with omega suture versus end to anterior rectal wall in colorectal anastomosis as regard post operative anastomotic leakage, bowel function, operative time and intra…
- Conditions
- End to End Anastomosis, Colorectal Anastomosis, End to Anterior Rectal Wall, Sigmoid Cancer
- Trial name
- NCT06546176
- Testing
- End to end with Omega suture, End to anterior rectal wall
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University