Clinical trials: Surgical Blood Loss
Gingival Recession, Mucogingival Surgery
V-Reverse Suture Technique Compared to Traditional Anchored Sling Suture in Treating Multiple Gingival Recession
The goal of this split-mouth pilot study is to study the effect of two different suturing techniques in root coverage using coronally advanced flap tunnel in multiple adjacent recession cases to see which technique will give…
- Trial name
- NCT07602829
- Testing
- coronally advanced tunnel with v-reverse suture, coronally advanced tunnel with anchored sling suture
- Where
- Jordan
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Foot and Ankle Surgeries, Bunion
Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Epidemiology of foot and ankle surgeries that present to the hospitals in the US are often underestimated. However there has been growing emphasis on identification of these injuries and practice patterns.
- Trial name
- NCT03653429
- Testing
- Tranexamic Acid, Normal saline
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Blood Loss, Surgical, Postoperative Hemorrhage
Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.
The goal of this clinical trial is to learn whether the Hemorai Vysio wearable device can be used safely and feasibly to track relative changes over time in tissue oxygen, hemoglobin-related signals, blood flow, and oxygen use…
- Trial name
- VYSIO-FEASIBIL (NCT07826637)
- Testing
- Wearable optical hemodynamic monitoring device
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hemorai Inc
Perioperative Bleeding, Venous Thrombosis
PeriOperative ISchemic Evaluation-3 Trial
This study is a multicentre, international, randomized controlled trial of tranexamic acid (TXA) versus placebo and, using a partial factorial design, of a perioperative hypotension-avoidance versus hypertension-avoidance…
- Conditions
- Perioperative Bleeding, Venous Thrombosis, Arterial Thrombosis
- Trial name
- POISE-3 (NCT03505723)
- Testing
- Tranexamic Acid, Perioperative hypotension-avoidance strategy, Perioperative hypertension-avoidance strategy
- Where
- 114 sites in United States, Australia and 21 more
- Volunteers
- 9,535 people, healthy volunteers welcome
- Sponsor
- Population Health Research Institute
Compassion, Bleeding
Comparison of Omentopexy and Clips on the Staple Line During Laparoscopic Sleeve Gastrectomy
Background: Bleeding through the staple line has been reported as one of the most common staple-related complications in laparoscopic sleeve gastrectomy (LSG).
- Conditions
- Compassion, Bleeding, Nausea, Postoperative, Readmission
- Trial name
- NCT06219668
- Testing
- Omentopexy group
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Post Partum Haemorrhage, Cesarean Section Surgery
Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section
To determine the effectiveness of prophylactic intravenous calcium chloride administered after cord clamping in reducing postpartum blood loss during intrapartum cesarean section.
- Trial name
- NCT07550413
- Testing
- Calcium Chloride
- Where
- Pakistan
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Pak Emirates Military Hospital
Abdominal Hysterectomy
Intravenous Ascorbic Acid Administration in Hysterectomy
vitamin C or ascorbic acid has known role in tissue repair. due to it's properties(water_soluble), vitamin c is not stored in the body and when depleted, the bleeding tendency will increase due to dysfunctional connective tissues…
- Trial name
- NCT03965637
- Testing
- vitamin C
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Maxilla Fracture, Malunited Maxilla Fracture
The Aim of This Study is to Compare the Outcome of Piezosurgery Versus Conventional Osteotomy in Maxillary Old Malunited Fractures in Terms of Intraoperative Blood Loss and Duration of Surgery..
To compare the outcomes of piezosurgery and conventional osteotomy in Le Fort I osteotomy for old malunited maxillary fractures in terms of mean duration of surgery and intraoperative blood loss.
- Trial name
- NCT07730320
- Testing
- PIEZO ELECTRIC DEVICE (PIEZOSURGERY), GROUP B CONVENTIONAL METHOD ( Mallet and OSTEOTOME
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Intraoperative Bleeding
Comparison Between Atenolol,Propnalol and Ivabradine
The aim of this work is to compare atenolol, propranolol, and ivabradine as a premedication to achieve bloodless field anesthesia primarily controlling heart rate in lumbar spine surgery.
- Trial name
- NCT06670690
- Testing
- Atenolol 50 MG, Propranolol Pill, Ivabradine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Postoperative Pain, Soft Tissue Bleeding
Comparison of Er,Cr:YSGG and Diode Lasers In Second Stage Implant Surgery
The study evaluates postoperative pain, intraoperative bleeding and wound healing after second stage implant surgery. Submerged implants were exposed with diode laser in Group 1 (n=20) and by using Er,Cr:YSGG laser in Group 2…
- Conditions
- Postoperative Pain, Soft Tissue Bleeding, Wound Heal
- Trial name
- NCT03819244
- Testing
- 940 nm Gallium Aluminum Arsenide Diode Laser, 2780 nm Er,Cr:YSGG Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Surgical Site Infection, Wound Complication
VAC Dressings for Colorectal Resections
Surgical Site Infections (SSIs) and wound complications are common occurrences following colorectal resection surgery. Incisional Negative Pressure Wound Therapy (iNPWT) has developing evidence for improving wound complication…
- Conditions
- Surgical Site Infection, Wound Complication, Wound Dehiscence, Seroma
- Trial name
- VACCRR (NCT02967627)
- Testing
- Incisional Negative Pressure Wound Therapy (iNPWT), Sterile Gauze Dressing
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Le Fort; I, Blood Loss
Impact of Different Instrument Modifications on Lateral Nasal Wall Osteotomy and Pterygomaxillary Separation in Le Fort I Surgery
The aim of this study is to investigate the effect of different instrument modifications on the customized osteotomy of the lateral nasal wall in Le Fort I surgery, focusing on the level of lateral nasal wall fractures and the…
- Trial name
- NCT06629935
- Testing
- orthognathic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Surgery, Postoperative Blood Loss
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at…
- Trial name
- NCT05774717
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pterygium, Subconjunctival Hemorrhage
Brimonidine Tartrate for Pterygium Surgery
Pterygium excision and conjunctival autograft surgery is commonly done to treat pterygiums. Excessive bleeding during the procedure creates a challenging operating field, prolongs surgery time, and prolongs healing.
- Trial name
- NCT04683159
- Testing
- Brimonidine Tartrate 0.15% Oph Soln, Brimonidine Tartrate 0.025% Oph Soln
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
Nasal Sinus; Inflammation, Opioid Abuse
Pain Management Following Sinus Surgery
This Study evaluates the effect of adding Non-steroidal anti-inflammatories (NSAIDs) to the post-operative pain management of sinus surgery patients and wether or not this addition reduces or eliminates the need for narcotic pain…
- Conditions
- Nasal Sinus; Inflammation, Opioid Abuse, Pain, Postoperative
- Trial name
- NCT03822962
- Testing
- Ibuprofen 600Mg Tablet, Standard Regimen | Tylenol
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Hematoma, Surgical Wound
Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study.
The post operative routine after Oculoplastic Surgery includes usage of cold compressions for symptomatic relief and decreasing of the edema and local hematomas in the first few days after the surgery.
- Conditions
- Hematoma, Surgical Wound, Surgery, Eye Bruise
- Trial name
- NCT03917641
- Testing
- Khat leaves
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
To Determine the Optimal Doses of Adrenaline in Preventing Blood Loos in Participants Undergoing Supraclavicular Flap Surgery
"The Effect Of Subcutaneous Epinephrine Dosage On Blood Loss In Surgical Incision"
Several studies have attempted to calculate the ideal epinephrine concentration for vasoconstriction, however there has been little consensus.
- Trial name
- NCT05670808
- Testing
- Epinephrine injection
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Blood Loss, Surgical, Blood Loss Anemia
Oral and Intravenous Tranexamic Acid in Lumbar Spine Surgery
The purpose of this project is to compare the effectiveness of two different but well accepted routes of administration of tranexamic acid in order to reduce blood loss and need for transfusion in patients undergoing lumbar spine…
- Trial name
- NCT03037515
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Cardiac Surgery, Bone Wax, NU-KNIT, Median Sternotomy, Deep Sternal Wound Infection, Surgical Site Infection
Surgicel NU-KNIT Vs Bone Wax on Median Sternotomy
Bone wax is traditionally used as part of surgical procedures to prevent bleeding from exposed spongy bone. It is an effective hemostatic device which creates a physical barrier.
- Trial name
- NBCS (NCT06869772)
- Testing
- Closure of sternotomy
- Where
- Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation