Clinical trials: Surgical Complication
Reperfusion Injury
Role of Volatile Anesthetics for Hepatic Protection
This study aims to evaluate the attenuation of ischemic-reperfusion injury in the liver after sevoflurane preconditioning. In the presence of sevoflurane, an attenuation of liver injury is hypothesized (diminished increase of…
- Trial name
- NCT00516711
- Testing
- Sevoflurane
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Zurich
Pain, Postoperative, Pelvic Organ Prolapse
Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery
The purpose of this randomized controlled trial is to determine whether, "ICE-T," a novel multimodal postoperative pain regimen composed of around the clock ice packs, toradol, and tylenol, has improved pain control intake…
- Trial name
- ICET (NCT03052816)
- Testing
- Ice T, Motrin/Percocet/Dilaudid for breakthrough
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue
The Effect of TEAS on the Quality of Early Recovery
During the past four decades, gynecologic laparoscopy has evolved from a limited method to an advanced operative approach that frequently serves as a substitute for laparotomy.
- Conditions
- C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue, Delayed Emergence From Anesthesia
- Trial name
- NCT02619578
- Testing
- TEAS, Con, propofol, remifentanil, vecuronium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guizhou Provincial People's Hospital
Placenta Accreta Spectrum
Evaluation of Different Surgical Approaches Used for Conservative Management of Placenta Accreta Spectrum in Sohag University Hospital
The objective of this study is to evaluate different intra-operative procedures to control bleeding in cases of PAS disorders aiming to determine the best procedure regarding maternal morbidity and mortality post-operatively, and…
- Trial name
- NCT05510076
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Postoperative Nausea and Vomiting
PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6
This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting.
- Trial name
- NCT06241547
- Testing
- electrical stimualtion via EmeTerm bracelet, antimetic drugs（ dexamethasone，ondansetron）
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Postoperative Pain, Ambulatory Surgery
Comparison Between Pre-operative Prescription Delivered During Anesthesia Consultation or Post-operative Prescription
This study evaluates the comparison of the incidence of postoperative home pain after ambulatory surgery with general anesthesia between a group with pre-surgical prescription delivered during anesthesia preoperative clinic and a…
- Conditions
- Postoperative Pain, Ambulatory Surgery, Anesthesia, Postoperative Complication
- Trial name
- AMBUPRESS (NCT03205189)
- Testing
- Comparison between pre-operative prescription and post-operative prescription
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Emergence Delirium
Remimazolam Reduces Emergence Delirium in Preschool Children Undergoing Laparoscopic Surgery by Sevoflurane Anesthesia
Emergence delirium (ED) is a manifestation of acute postoperative brain dysfunction that occurs with a relatively high frequency after pediatric anesthesia.
- Trial name
- NCT04621305
- Testing
- normal saline, Bolus Remimazolam, Continuous Infusion Remimazolam
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Obesity, Surgical Site Infections
Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery
The investigators aim to show that single use negative pressure dressings can decrease the rate of wound complications in obese women (BMI > 40 kg/m2) undergoing cesarean delivery at a tertiary medical center by randomizing women…
- Conditions
- Obesity, Surgical Site Infections, Wound Complications, Complications; Cesarean Section
- Trial name
- NCT02799667
- Testing
- Standard Dressing, Negative Pressure Wound Therapy Dressing
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Postoperative Pain
Analgesic Preoperative/Postoperative Dexketoprofen Trometamol in Third Molar Surgery
The purpose of the present investigation is to evaluate the effectiveness of the preoperative administration of Dexketoprofen Trometamol, employing the third molar surgery model, when compared to postoperative administration of…
- Trial name
- NCT02380001
- Testing
- Dexketoprofen trometamol, Preoperative control
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Daniel Chavarría Bolaños
Post Operative Nausea and Vomiting, Rescue Emetic Therapy
Rescue Emetic Therapy for Children Having Elective Surgery
To compare ondansetron, metoclopramide, diphenhydramine, and placebo in order to determine which anti-emetic is most efficacious as a "rescue therapy" for pediatric patients ages 3-18 who have post-operative vomiting after a…
- Trial name
- RETCHES (NCT01067677)
- Testing
- Metaclopramide, Ondansetron, diphenhydramine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Franklyn Cladis
Postoperative Pain, Acute
Modified Versus Conventional Serratus Anterior Plane Block
comparing preemptive analgesia with ultrasound guided modified serratus anterior plane block versus ultrasound guided serratus anterior plane block
- Trial name
- NCT05661253
- Testing
- 25 ml of bupivacaine 0.25% via serratus anterior block, 25 ml of bupivacaine 0.25% via modified serratus anterior palne block
- Where
- Egypt
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain, Acute
Comparison of the Effects of Tenoxicam and Paracetamol on Postoperative Pain
Postoperative pain is generally caused by inflammation and oedema related to tissue trauma. Surgical tissue trauma is caused by many factors such as cotery-related burns, surgical incisions, dissections, and instrumental…
- Trial name
- NCT05508451
- Testing
- Double jaw surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Urologic Diseases
10 Minutes Prewarming and Warmed Intravenous Fluid on Core Temperature
Hypothermia occurs frequently during general anesthesia. This study is to evaluate the efficacy of 10 minutes of prewarming and warmed fluid during urologic surgery.
- Trial name
- NCT04991272
- Testing
- prewarming and warmed fluid infusion
- Where
- South Korea
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Inje University
Surgical Wound Infection
Feasibility Trial for Postoperative Wound Surveillance Using Smartphones
The proposed trial is a pilot to test a smartphone application (app) that will ultimately allow patients to take and transmit photos of their postoperative wounds from home and relay other symptom information.
- Trial name
- NCT02735525
- Testing
- Smartphone monitoring
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Tibial Fractures, Fibula Fracture
Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation
Palmitoylethanolamide (PEA), a non-psychoactive cannabis compound derived from peanuts, egg yolks, and soybeans, is an Endogenous FA Amide produced in the body as a biological response and a repair mechanism in chronic…
- Conditions
- Tibial Fractures, Fibula Fracture, Knee Fracture
- Trial name
- NCT05317676
- Testing
- Palmitoylethanolamide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Pain, Postoperative
Flexibility of Cognition And Persistent Pain
This observational study aims to determine the association between preoperative cognitive flexibility and the risk of developing PPSP by preoperative administration of cognitive tests.
- Trial name
- FlexCAPP (NCT02579538)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Surgical Wound Infection
Closed Incision Negative Pressure Wound Therapy for the Prevention of Surgical Site Infections in Abdominal Surgery
Surgical site infections (SSI) are a frequent complication in abdominal surgery. SSI lead to worse outcomes for the affected patients and significantly higher healthcare costs.
- Trial name
- CISSI (NCT06068517)
- Testing
- Closed incision negative pressure wound therapy, Standard dressing
- Where
- Switzerland
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Surgical Site Infection
Skin Staples vs Polypropylene in Elective Laparotomy
Surgical site infection (SSI) is one of the most common postoperative complications following elective laparotomy and contributes significantly to patient morbidity, prolonged hospital stay, and increased healthcare costs.
- Trial name
- NCT07781878
- Testing
- Skin staples, Polypropylene skin suture
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Post Operative Pain, Spine Surgery
Effects of Continuous ESP Catheters on Recovery, Pain and Opioid Consumption After Multilevel Spine Surgery
Single-shot erector spinae plane (ESP) blocks (ESPB) are emerging as an intervention to improve pain and minimize opioid consumption after lumbar spine surgery.
- Trial name
- NCT05494125
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Nausea and Vomiting
Dextrose Containing Fluid and the Postoperative Nausea and Vomiting in the Gynecologic Laparoscopic Surgery
The investigators tested the hypothesis that administration of intravenous dextrose as a maintenance fluid in gynecologic laparoscopic surgery would reduce the incidence and severity of postoperative nausea and vomiting (PONV)…
- Trial name
- NCT03139383
- Testing
- dextrose solution, saline solution
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
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