Clinical trials: Surgical Condition
Hypoglycemia
GLP1R-imaging in Hypoglycemia
Hyperinsulinemic hypoglycemia (HH) is a rare complication that occurs 1 to 5 years after gastric bypass surgery. The underlying mechanism of this complication is not yet completely understood.
- Trial name
- NCT03182192
- Testing
- 68Ga-NODAGA-exendin-4 PET/CT
- Where
- 2 sites in Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Malocclusion, Angle Class III
Evaluation of Surgical Outcomes of Patients Treated With the Surgery First Approach and Aligners
The purpose of this prospective study is to compare treatment outcomes and the quality of life of skeletal Class III patients treated with conventional fixed appliances and aligners undergoing Surgery-first approach.
- Trial name
- NCT05822271
- Testing
- Orthognathic Surgery
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Acute Kidney Injury
A Clinical Score to Predict Acute Kidney Injury After Heart Valve Replacement Surgery
Acute kidney injury (AKI) is a common and severe complication of cardiac surgery. The main stay treatment remains preventive with no clear evidence supporting any therapeutic interventions.
- Trial name
- NCT04237636
- Where
- China
- Volunteers
- 3,392 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Peri-implantitis
Implant Survival After Surgical Treatment of Peri-implantitis of Infra-bony Defects
To report the 10 years outcomes of a reconstructive surgical protocol for peri-implantitis defects with different morphologies, by means of deproteinized bovine bone mineral with 10% collagen (DBBMC).
- Trial name
- Bony defects (NCT07809334)
- Testing
- Reconstructive therapy
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Laparoscopy
Effect of Music on Inflammatory Response During Laparoscopic Surgery
This study evaluates the effect of per-operative music on the bio-molecular inflammatory response in laparoscopic surgery. Per-operative music intervention will be given to the test group via headphones while the control group…
- Trial name
- NCT02827292
- Testing
- music, No music, Laparoscopic Surgery
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sir Ganga Ram Hospital
Obesity
Research Study of Nutritional Methods to Reduce Body Fat Percentages in Overweight and Obese Populations
The purpose of this study is to compare the use of personalized low-fat meal plans vs. non-personalized low-fat meal plans and the results in body fat reduction in overweight and obese subjects 25 to 45 years of age.
- Trial name
- NCT00487344
- Testing
- Non-Personalized Meal Planning, Personalized Meal Planning and Dietetic Consultation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Central FITT, Inc
Hip Fractures, Acetabular Fracture
Static Balance Disorders in Patients After Surgical Treatment of Hip Acetabular Fractures
The mechanism of maintaining balance is a complex phenomenon, involving numerous systems of human body. High-energy trauma resulting in acetabular fracture damages some of the elements composing this delicate mechanism…
- Conditions
- Hip Fractures, Acetabular Fracture, Balance; Distorted, Disability Physical
- Trial name
- NCT04902209
- Testing
- postural stability measurements
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
oPAP Should be > 25mmHg in Right Heart Catheterization at Rest, There Should be Patients Who Will Undergo Non-cardiac and Non-obstetric Surgery
Postoperative Morbidity / Mortality Rates of Patients With Pulmonary Hypertension
Pulmonary hypertension (PHT) is an oPAP ≥25 mmHg as assessed by right heart catheterization at rest. It is divided into 5 groups according to its etiology and mechanism.
- Trial name
- PulmonaryHT (NCT05565911)
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Baskent University
Post Surgical Pain, Analgesia
HONEY for the Treatment of POst-Tonsillectomy Pain
Double-blind, randomised, placebo controlled, single-site trial in adults to compare the effect of Manuka honey with standard of care compared to placebo with standard of care on post-tonsillectomy pain and postoperative…
- Trial name
- HONEY-POT (NCT06275698)
- Testing
- Manuka honey MGO 1000, Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- East and North Hertfordshire NHS Trust
Epilepsy
Cartography of Functional and Epileptic Cerebral Areas by Functional MRI and Electroencephalography in Epileptic Patients Before and After Surgery
Exploring the reorganization (plasticity) of neuroanatomic networks associated with language and memory in patients with left (or dominant hemisphere) temporal lobe epilepsy using functional MRI (fMRI)
- Trial name
- NCT03102957
- Testing
- functional MRI
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Atelectasis, Compliance, Patient
Restoration of Pulmonary Compliance After Laparoscopic Gynaecologic Surgery Using a Recruitment Maneuver
To investigate the hypothesis that an alveolar recruitment maneuver after the release of pneumoperitoneum would restore the lung compliance to the baseline values after a laparoscopic gynaecologic surgery.
- Trial name
- NCT06203665
- Testing
- Recruitment Maneuver
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Panagiota Griva
Peri-Implantitis
Evaluate the Influence of Electromagnetic Field as an Adjunctive Non Surgical Treatment in Implant With Peri-implantitis
the aim of the study is to compare between two non-surgical methods of treatment of peri-implantitis by using debridement and placing an healing abutment with electomagnetic field (MED-Magdent Miniaturized Device) in the test…
- Trial name
- NCT04213144
- Testing
- Magdent Cap MED
- Where
- Israel
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Postoperative Complications
Effect of Gabapentin on Postoperative Morphine Consumption After Sleeve Gastrectomy
The evidence regarding effects of pain modulator like gabapentin on postoperative pain after sleeve gastrctomy is sparse. Gabapentin has anti-hyperalgesic and postoperative opioid-sparing properties.This study will highlight the…
- Trial name
- NCT03023501
- Testing
- Gabapentin
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Saud University
Closed Reduction Surgery for Nasal Bone Fracture
The Relationship Between the Surgery-related Anxiety and HRV: Prediction for Aggressive Emergence Behavior
Heart rate variability (HRV) is known to reflect the balance of autonomic nervous system. Anxiousness, which tend to result from the deficient action of parasympathetic nervous system, likely to show low HRV.
- Trial name
- NCT02282865
- Where
- South Korea
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Periodontal Disease Stage 2
Interleukin-34 Level in Periodontal Disease
Aim of the study: 1. To investigate changes in the levels of Interleukin 34 (IL-34) in the Gingival crevicular fluid(GCF) of patients with stage II periodontitis patients before and after nonsurgical periodontal therapy and…
- Trial name
- NCT05962567
- Testing
- Non surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Minimally Invasive Surgical Procedure, Hysterectomy
The Impact of Post-operative Voiding Trial on Length of Stay Following Laparoscopic Hysterectomy: A Prospective, Randomized Control Trial
The aim of this study is to investigate the impact of an active voiding trial compared to a passive voiding trial on time to discharge following a planned same day discharge laparoscopic hysterectomy.
- Conditions
- Minimally Invasive Surgical Procedure, Hysterectomy, Urinary Retention
- Trial name
- NCT04487600
- Testing
- Active voiding trial
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Breast Cancer With Intraoperative Radiotherapy Followed by Hypofractionated External Beam Radiotherapy
To evaluate cosmetic outcomes after conservative surgery for breast cancer with INTRABEAM followed by hypofractionated external beam radiotherapy
- Trial name
- IORT_BREAST (NCT05498311)
- Testing
- Intraoperative Radiotherapy (IORT), Breast conservative surgery, External Beam Hypofractionated Radiotherapy (EBRT)
- Where
- Spain
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Prevention of Surgical Site Infections
Tumescent Antibiotic Delivery Pharmacokinetics
Tumescent Antibiotic Delivery (TAD) is a technique for improving the prevention of surgical site infections (SSI). TAD involves the subcutaneous infiltration of tumescent local anesthesia (TLA) containing water soluble…
- Trial name
- NCT01046981
- Testing
- Tumescent Antibiotic Delivery of cefazolin with or without metronidazole, Intravenous Antibiotic Delivery
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.
Pain Syndrome
Pain After Removal of Mandibular Third Molars With or Without Advanced Platelet-rich Fibrin
Pain is the most common complication following surgical removal of an impacted mandibular third molar. Several risk factors may increase the intensity and duration of pain following removal of mandibular third molars.
- Trial name
- NCT06377839
- Testing
- Advanced platelet-rich fibrin in the ekstraction socket
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Acute Kidney Injury
The Effect of the Hydroxyethyl Starch on Kidney Injury in Pediatric Cardiac Surgery
The investigator will evaluate the influence of colloid administration on postoperative acute kidney injury in pediatric patients undergoing cardiac surgery under cardiopulmonary bypass.
- Trial name
- NCT02599155
- Testing
- Crystalloid, Colloid
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
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