Clinical trials: Surgical Condition
Strabismus
Deep Neuromuscular Blockade in Strabismus Surgery
The purpose of this study is to determine if inducing a moderate or greater neuromuscular block (TOF count 0-3) when performing a neuromuscular block in pediatric patients aged 3 to 18 years undergoing strabismus surgery under…
- Trial name
- NCT05882643
- Testing
- moderate to deep neuromuscular blockade, shallow to minimal neuromuscular blockade
- Where
- South Korea
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Periodontal Pocket, Impacted Third Molar Tooth
Evaluation of Two Different Grafting Techniques After Mandibular Impacted Third Molar Surgery
This study evaluates the effectiveness of using Mineralized Plasmatic Matrix and β-tricalcium phosphate that placed to extraction socket as a graft material in terms of periodontal damage occurred in the distal aspect of the…
- Conditions
- Periodontal Pocket, Impacted Third Molar Tooth, Impacted Teeth With Abnormal Position
- Trial name
- NCT04366635
- Testing
- Impacted third molar surgery, Application of mineralised plasmatic matrix, Application of β-tricalcium phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Cardiac Surgery, Postoperative Cognitive Dysfunction
The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery
To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery
- Conditions
- Cardiac Surgery, Postoperative Cognitive Dysfunction, Neurologic Manifestations
- Trial name
- NCT06655025
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pneumoperitoneum Increases Mean Expiratory Flow Rate
Pneumoperitoneum Increases Mean Expiratory Flow Rate: an Observational Study in Healthy-lung Patients
Upon introducing pneumoperitoneum our research team noticed a reduction in expiration time displayed on the screen of the anesthesia machine.
- Trial name
- NCT06212258
- Testing
- Abdominal Laparascopy
- Where
- Hungary
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Balázs Sütő
Ventilator-Induced Lung Injury
Pressure Support Ventilation During Laparoscopic and Abdominal Robotic Surgery.
This study is a single-center, blind, prospective, randomized, controlled trial of pressure support ventilation (PSVpro) versus pressure control ventilation - volume guaranteed (PCV - VG) during laparoscopic and robotic abdominal…
- Trial name
- NCT04815733
- Testing
- Mandatory ventilation, pressure support ventilation
- Where
- Russia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Moscow Clinical Scientific Center
Flumazenil Adverse Reaction, Ambulatory Surgery
Reversal of Remimazolam by a Single Dose of Flumazenil
Remimazolam, a brand-new sedative which has benzodiazepine property. It is an ultra-short acting sedative and regarded as a proper drug for procedural sedation.
- Conditions
- Flumazenil Adverse Reaction, Ambulatory Surgery, Postoperative Nausea, Remimazolam
- Trial name
- NCT05382806
- Testing
- Flumazenil
- Where
- South Korea
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Periodontal Pocket
Concentrated Platelet Rich Fibrin (C-PRF) as Adjunct to Non-surgical Periodontal Therapy
The current study is a prospective randomised split mouth study to evaluate the effect of concentrated Platelet Rich Fibrin as an adjunct to the scaling and root planing
- Trial name
- NCT05958147
- Testing
- C-PRF
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Pain, Postoperative
Fascial Closure Technique After Gynecologic Laparoscopic Surgery and Postoperative Pain
Our study aims to determine postoperative pain outcomes when comparing port site > 10 mm fascial closure with traditional direct closure versus use of laparoscopic fascial closure device in patients undergoing minimally invasive…
- Trial name
- NCT04765306
- Testing
- Traditional Direct Fascial Closure, Fascial Closure Device
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Jessica G Putman
Insulin Resistance
Carbohydrate Loading in Lowering Perioperative Insulin Resistance in Pediatric Surgery
It is a double blinded randomized controlled trial interventional study, examining the effect of carb loading given prior to surgery on preventing post operative insulin resistance in pediatric patients undergoing elective surgery
- Trial name
- NCT07545538
- Testing
- Carbohydrate loading
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Growth Factors, Combined Defect of, Gingival Recession
Growth Factors in the Treatment of the Multiple Gingival Recessions
The purpose of this study was to compare and evaluate the clinical effects of Concentrated Growth Factor (CGF) and Advanced Platelet-Rich Fibrin (A-PRF) applied together with Coronally Advanced Flap (CAF) technique using a…
- Trial name
- NCT05319938
- Testing
- CAF only, CAF+CGF, CAF+A-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Gingival Recession
Gingival Recession Treatment With Concentrated Growth Factor(CGF)
Platelet concentrates(PC) are used in the field of periodontology and implantology for the content necessary key cells and growth factors to accelerate healing and to provide regeneration.
- Trial name
- NCT03020732
- Testing
- test groups, control groups
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Gazi University
Ileus Postoperative, Postoperative Nausea and Vomiting
Postoperative Gastric Point of Care Ultrasound (G-POCUS) in Abdominal Surgery
The purpose of this research is to determine if gastric point of care ultrasound (G-POCUS) can be used to help clinicians determine when to feed patients or when to insert or remove nasogastric tubes for patients recovering from…
- Trial name
- NCT05796063
- Testing
- gastric point of care ultrasound
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Gynecologic Disease
Traditional Versus Virtual Reality for Surgical Skills for ObGyn Residents
This study will verify if a comprehensive laparoscopic curriculum using virtual reality demonstrates skills transfer to the operating room, compared to the traditional teaching method.
- Trial name
- SIMUTEC (NCT03395821)
- Testing
- Conventional training, Virtual Reality+conventional training
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Meniscus Disorder, Narcotic Use
Nonopioid Analgesia After Arthroscopic Meniscus Surgery
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of arthroscopic meniscus surgery: a treatment group given…
- Trial name
- NCT03820193
- Testing
- Celecoxib, Hydrocodon/Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Urinary Retention Postoperative, Pelvic Organ Prolapse
Catheter Management After Pelvic Reconstructive Surgery
This is a randomized controlled trial comparing plug-unplug catheter management, continuous drainage catheter systems and patients that do not get discharged with catheters after inpatient pelvic reconstructive surgery.
- Trial name
- NCT03071211
- Testing
- Plug-unplug catheter management, Continuous drainage catheter management
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Safety Issues, Post Operative Pain
Safety and Efficacy of Wide Awake Local Anesthesia no Tourniquet Technique (WALANT) in Ankle Removal of Implant Surgery
Safety and efficacy of wide awake local anesthesia no torniquet technique (WALANT) in ankle surgery. Studying risks and benefits from WALANT compared to general anesthesia .
- Conditions
- Safety Issues, Post Operative Pain, Local Anesthetic Complication
- Trial name
- NCT05864664
- Testing
- Wide awake local anaesthesia no tourniquet technique
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ali Lari
Facial Swelling, Pain
Effects of Low-level Laser Therapy After Surgical Removal of Impacted Lower Third Molar
Goal: The aim of this study was to evaluate the effects of low-level laser (LLL) after surgical removal of impacted lower third molars (ILTM).
- Conditions
- Facial Swelling, Pain, Trismus
- Trial name
- NCT04280809
- Testing
- GaAlAs laser
- Where
- Vietnam
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Gall Stones (& [Calculus - Gall Bladder]), Surgery
Major Surgery as a Risk of Gall Stone Disease?
Gall stone disease is one of the most common diseases occurring in the world as well as in our country, Nepal. This disease is problematic to a lot of patients and poses a huge economic burden to the country.
- Trial name
- NCT04675190
- Testing
- Major abdominal Surgery
- Where
- 3 sites in Nepal
- Volunteers
- 755 people, healthy volunteers welcome
- Sponsor
- Nepal Medical College and Teaching Hospital
Obesity, Glucose Intolerance
A Biological Atlas of Severe Obesity (Biological Tissue Collection)
Type 2 diabetes and obesity are both multifactorial diseases resulting from gene-environment interactions. However, this interaction, as well as the specific effect of each polymorphism, remains poorly understood.
- Conditions
- Obesity, Glucose Intolerance, Diabetes
- Trial name
- ABOS (NCT01129297)
- Where
- France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Sepsis, Surgery
Inflammatory Mediators of Acute Kidney Injury in Intensive Care
Acute kidney injury (AKI) affects more than 50% of patients admitted to the intensive care unit. The most common underlying cause is sepsis. Severe AKI in combination with sepsis is associated with high mortality.
- Conditions
- Sepsis, Surgery, Acute Kidney Injury
- Trial name
- PronMed (NCT03720860)
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uppsala University
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