Clinical trials: Surgical Condition
Pulmonary Disease
Effect of Glossopharyngeal Versus Diaphragmatic Breathing Exercise on Pulmonary Function After Decortication Surgery
This study will be conducted to compare between the effect of glossopharyngeal and diaphragmatic breathing exercises on pulmonary functions after decortication surgery
- Trial name
- NCT06518759
- Testing
- traditional chest techniques, Glossopharyngeal breathing exercise, Diaphragmatic breathing exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Varicose Veins
Long-term Ultrasound Guided Foam Sclerotherapy Versus Classical Surgical Stripping Study
The aim of this study is to investigate the long-term follow-up of the previously conducted FOAM study.
- Trial name
- NCT02304146
- Where
- 3 sites in Netherlands
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Heart Defects, Congenital
Transcatheter Versus Surgical Closure of Ventricular Septal Defect: A Comparative Study
The aim of this study is to compare Safety, efiicacy and clinical effects of surgical versus transcatheter closure of ventricular septal defect (VSD ).
- Trial name
- NCT05306483
- Testing
- Ventricular septal defect closure surgery, Ventricular septal defect closure catheter
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Emergence Delirium
Remimazolam Reduces Emergence Delirium in Preschool Children Undergoing Laparoscopic Surgery by Sevoflurane Anesthesia
Emergence delirium (ED) is a manifestation of acute postoperative brain dysfunction that occurs with a relatively high frequency after pediatric anesthesia.
- Trial name
- NCT04621305
- Testing
- normal saline, Bolus Remimazolam, Continuous Infusion Remimazolam
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Death, Stroke
Postoperative Atrial Fibrillation and Long-term Survival
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.
- Conditions
- Death, Stroke, Myocardial Infarction
- Trial name
- POAF (NCT02349269)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Ketamine-Induced Mood Disorder
The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia
Optimal multimodal opioid-sparing analgesic technique is considered as one of the most important Enhanced recovery pathways (ERPs) or enhanced recovery after surgery (ERAS) interventions that mitigate the undesirable effects of…
- Trial name
- NCT05474183
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Periodontal Regeneration
Minimally Invasive Flap With Platelet Rich Fibrin or Growth Factor Enhanced Matrix in Treatment of Intrabony Defect
Twenty-one intra-bony defects in fifteen systemically healthy patients with moderate to severe chronic periodontitis were randomly classified into 3 groups, 7 sites each.
- Trial name
- RCT (NCT04786327)
- Testing
- Minimal invasive flap technique, Minimally invasive flap with root conditioning (EDTA) and platelet rich fibrin, minimally invasive flap with root contioning by EDTA and growth factor enhanced matrix GEM21S
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tanta University
Scoliosis, Scoliosis Kyphosis
Effect of Adult Spinal Deformity Surgery on Functional Reach
Adult spinal deformity (ASD) is a common spinal condition that often impacts an individual's ability to stand and maintain an upright posture.
- Trial name
- NCT06258161
- Testing
- Spinal Fusion, No intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Intra-bony Pockets, Periodontitis
Biologicals in Management of Intra-Bony Defects
The aim is of this study is to evaluate and compare the effects (clinical and radiological) of different biomaterials on the repair of bone defects around the teeth.
- Trial name
- NCT07292870
- Testing
- Minimally invasive surgical treatment of the intra-bony defects, Use of the xenograft Bio-Oss® Collagen during the surgery, Use of enamel matrix derivative (Emdogain®)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Analgesia
Bilateral Transversus Thoracic Muscle Plane Block as Analgesic in Open Heart Surgeries by US.
OPEN CARDIAC SURGERY may cause severe postoperative pain and promote a high risk of chronic pain if not treated adequately, that is caused by multiple factors; sternotomy, costotransverse and costovertebral joint distensions…
- Trial name
- NCT04116554
- Testing
- 0.25% bupivacaine., 0.9%saline
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Kidney Cancer
Virtual 3D Modelling for Improved Surgical Planning of Robotic-assisted Partial Nephrectomy
To establish whether surgical planning using virtual 3D modelling (Innersight 3D) improves the outcome and cost-effectiveness of RAPN, allowing more patients to benefit from minimally-invasive procedures.
- Trial name
- VISP (NCT05109182)
- Testing
- Innersight3D
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Innersight Labs Ltd
Suture, Complication, Hand Infection
STASSH - TRAUMA - Absorbable vs Non-Absorbable Sutures in Trauma Hand Surgery
An RCT will be set up to compare outcomes between two groups of hand surgery patients. These are: Emergency hand surgery patients - randomized to either absorbable or non-absorbable suture.
- Conditions
- Suture, Complication, Hand Infection, Skin Infection, Scar
- Trial name
- STASSH-TRAUMA (NCT06247761)
- Testing
- Skin closure at end of hand surgery
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Mid and South Essex NHS Foundation Trust
Quality of Life
Acupuncture and Integrative Care in Gynecological Surgery
Patients undergoing surgical procedures for gynecological cancer are frequently challenged by intense anxiety prior to surgery, reflecting the accompanying uncertainty regarding the diagnosis, treatment and prognosis of their…
- Trial name
- NCT03560388
- Testing
- Acupuncture and touch/relaxation
- Where
- Israel
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Pain
Analgesic Efficacy & Safety of Intravenous (IV) Acetaminophen Versus Placebo for the Treatment of Postop Pain
This research study will look at the pain relieving ability and safety of using repeated doses of intravenous (into the vein [IV]) acetaminophen in the treatment of moderate postoperative pain after planned or elective abdominal…
- Trial name
- NCT00564486
- Testing
- IV Acetaminophen
- Where
- 17 sites in United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Mallinckrodt
Varicose Veins, Wound Infection
A Randomised Study to Assess Betadine in the Groin Wound of Patients Undergoing Primary Varicose Vein Surgery
To investigate whether Betadine can reduce infection rates and recurrence rates following varicose veins surgery in a randomized double blind placebo controlled study.
- Conditions
- Varicose Veins, Wound Infection, Recurrence
- Trial name
- NCT00500669
- Testing
- Betadine
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Hobart Hospital
Pancreatic Cancer
Stool Testing for Pancreatic Cancer
The purpose of this study is to determine if pancreatic cancer/pre-cancer can be detected in early stages through the molecular analysis of stool samples.
- Trial name
- NCT01104129
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Columbia University
Morbid Obesity, Overweight
Pharmacokinetics in Morbid Obesity After Bariatric Surgery
Morbid obesity (MO) is associated with several disorders such as hypertension, type 2 diabetes, dyslipemia and degenerative arthropathy that require pharmacological treatment.
- Trial name
- FAROBE/1 (NCT01086722)
- Testing
- "karolinska cocktail"
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Fundacion IMIM
Alveolitis of Jaw, Alveoli, Teeth; Inflammation
Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery
In the everyday clinical practice the incidence of minor complications is approximately 15-20% of the total number of third molar removals. Alveolitis (dry socket syndrome) may arise in 30-40% of the surgical tooth removals.
- Conditions
- Alveolitis of Jaw, Alveoli, Teeth; Inflammation, Dry Socket, Impacted Third Molar Tooth
- Trial name
- AITS (NCT03741894)
- Testing
- Iodoform, Wound closure using sutures, Chlorhexidine
- Where
- Hungary
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Sars-CoV2
Incidence of COVID-19 Test Conversion in Post-surgical Patients
The current Sars-CoV-2 (COVID-19) pandemic has created major changes in how physicians perform routine healthcare for our patients, including elective and non-elective surgical procedures.
- Trial name
- NCT04392323
- Testing
- COVID-19 PCR and Serology
- Where
- 2 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Surgical Site Infection, Microbial Colonization
P.Acnes Colony Count Following Subdermal Cefazolin
The specific outcome is to determine whether the colony count of Propionibacterium acnes, one of the commonest causes of shoulder infection and not eradicated by conventional forms of surgical preparatory solutions and…
- Trial name
- NCT03853096
- Testing
- Cefazolin
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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