Clinical trials: Surgical Condition
Retinal Detachment, Epiretinal Membrane
PIONEER: Intraoperative and Perioperative OCT Study
OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician.
- Conditions
- Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
- Trial name
- PIONEER (NCT02423161)
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Healthy Individuals (Controls), Vascular Surgery Patients With Acute Thrombosis
Haemodialysis Alters Hypercoagulability of Blood in Dialysis Patients
Primary Objective: To develop a thrombotic event risk assessment model integrating serum biomarkers (TM, TAT, t-PAIC, PIC) with clinical data, systematically compare its predictive performance across healthy populations, vascular…
- Conditions
- Healthy Individuals (Controls), Vascular Surgery Patients With Acute Thrombosis, Dialysis Patients
- Trial name
- TAT-t-PAIC (NCT07098676)
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Ai Peng
Acupuncture, Ear, Gastroparesis
The Role of AAT After Abdominal Surgery Based on RWS
Delayed gastric emptying (DGE) after surgery mainly occurs after gastrointestinal surgery A functional gastric emptying disorder, clinically characterized by weak or absent gastric peristalsis, gastric motility disorders, or…
- Trial name
- NCT06580197
- Testing
- Auricular Acupoint Therapy
- Where
- China
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Morbid Obesity, Obstructive Sleep Apnea
Laparoscopic Adjustable Gastric Banding With Truncal Vagotomy
Laparoscopic Adjustable Gastric Banding (LAGB) is a gold standard in the surgical treatment of morbid obesity. We hypothesize that the addition of truncal vagotomy (cutting of nerves to the stomach) will produce greater weight…
- Conditions
- Morbid Obesity, Obstructive Sleep Apnea, Hypertension, Urinary Incontinence
- Trial name
- NCT00329862
- Testing
- Laparoscopic Truncal Vagotomy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Central Carolina Surgery, PA
Emergence Agitation, Pain
Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Emergence agitation (EA) occurs in up to 67% of pediatric patients after anesthesia for bilateral myringotomy tubes (BMT, "ear tubes").
- Trial name
- NCT01737593
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anxiety Acute, Anxiety Fear
Paediatric Peri-operative Anxiety: Does the Little Journey App Help?
To evaluate the clinical effectiveness of a virtual reality psychological preparation app at reducing peri-operative anxiety and its associated sequelae in children aged 3-12 years old undergoing ambulatory surgery compared to…
- Conditions
- Anxiety Acute, Anxiety Fear, Peri-operative, Psychological Distress
- Trial name
- NCT03797716
- Testing
- Little Journey app
- Where
- 17 sites in United Kingdom
- Volunteers
- 596 people, healthy volunteers welcome
- Sponsor
- University College, London
Cataracts
Accuracy of the Galilei Analyzer to Calculate the Effective Corneal Power After Corneal Refractive Surgery
The purpose of this study is to determine the accuracy of the Galilei corneal analyzer to calculate the effective corneal power (keratometry, corneal curvature) in patients who have undergone both corneal refractive surgery and…
- Trial name
- Galilei (NCT00934804)
- Testing
- Galilei dual Scheimpflug analyzer
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pain
Low Dose Methoxyflurane and Out-Patient Aesthetic Surgery and Facial Filler
The aim of the study is to generate real-world evidence on the effectiveness, safety and additional parameters of low dose methoxyflurane (PENTHROX®) in: aesthetic surgeries (eg.
- Trial name
- NCT04292808
- Testing
- Methoxyflurane
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Verso Surgery Centre
Gingival Recessions, Generalized
Surgical Treatment for Gingival Recessions After Orthodontic Treatment
Modification of the periodontal soft tissue phenotype and coverage of exposed root surfaces in patients who have undergone orthodontic treatment.
- Trial name
- NCT07763808
- Testing
- Coronally advanced flap and a de-epithelialized soft tissue graft, Coronally advanced flap and a subepithelial connective tissue graft, Coronally advanced flap and Mucoderm soft tissue collagen graft
- Where
- Azerbaijan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors
Pain
Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion
The investigators theorize that the application of a lidocaine-prilocaine cream 5-10 minutes prior to the administration of a paracervical block could decrease pain associated with its administration and pain with abortion…
- Trial name
- NCT03508804
- Testing
- Lidocaine-Prilocaine Cream, 1% Lidocaine Paracervical Block
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Sepsis
Circulating Stem Cells, SDF-1, HIF-1 and Sepsis's Indices in Emergency Abdominal Surgical Patients
Septic shock is a systemic inflammatory response syndrome with acute circulatory failure secondary to a documented infection. It is the most feared complication in ICU patients, with a 50% mortality rate.
- Trial name
- NCT02589535
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Foggia
COVID-19 Pandemic, Educational Problems
The Impact of Covid 19 Pandemic on the Training of General Surgery Residents
The educational process of general surgery residents is a very important step in every surgeon's career, which is often overlooked or neglected.
- Trial name
- NCT05069116
- Testing
- Training in surgery
- Where
- Romania
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Perioperative/Postoperative Complications, Surgery
Validity of Aortic Pulse Wave Velocity in Predicting the 6- Minute Walking Test Before Major Non-cardiac Surgery
Methods: Prospective observational study in adult patients requiring preoperative evaluation Objectives: To determine the correlation between the aortic pulse wave velocity (AoPWV) and the distance walked in the 6-minute walk…
- Conditions
- Perioperative/Postoperative Complications, Surgery, Exercise Tolerance
- Trial name
- 6WAVE (NCT03866915)
- Testing
- Aortic pulse wave velocity measurement, 6 minutes walking test
- Where
- 3 sites in Spain
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Pain, Other Surgical Procedures
Comparison of the Clinical Efficacy of Ketoprofen, Associated or Not With Omeprazole in Lower Third Molar Removal
The control of pain, swelling and trismus in patients undergoing oral and maxillofacial surgery is frequently performed through the administration of non-steroidal anti-inflammatory drugs (NSAIDS).
- Trial name
- NCT02730026
- Testing
- Ketoprofen, Ketoprofen and Omeprazole
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Luis Fernando Simoneti
Postoperative Complications, Colorectal Cancer
Frailty Score and Postoperative Morbidity in Colorectal Cancer Surgery
This prospective observational study aims to evaluate the independent predictive value of the Edmonton Frailty Index (EFI) in estimating postoperative morbidity among older patients undergoing elective colorectal cancer surgery.
- Conditions
- Postoperative Complications, Colorectal Cancer, Frailty
- Trial name
- NCT06866678
- Testing
- Observational Data Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Hepatocellular Carcinoma (HCC)
A Prospective Study of Cadonilimab in Hepatocellular Carcinoma After Radical Surgery With High Risk of Recurrence
This study aims to compare the safety and tolerability of cadonilimab applied after curative hepatectomy for hepatocellular carcinoma combined with high - risk recurrent factors.
- Trial name
- NCT06851104
- Testing
- Cadonilimab (AK104)
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Cataract
Topical Bromfenac for Intraoperative Miosis and Pain Reduction
To evaluate the effect of bromfenac ophthalmic solution 0.09% for reduction of intraoperative miosis and pain in patient who have undergone femtosecond laser-assisted cataract surgery.
- Trial name
- NCT03831984
- Testing
- 0,09% Bromfenac, 0,1% sodium hyaluronate
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de La Luz
Obesity
Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery
Bariatric surgery (BS), especially procedures like Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), is the most effective treatment for obesity.
- Trial name
- DIBASH (NCT06538948)
- Testing
- Bariatric Surgery
- Where
- 2 sites in Switzerland
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Surgery in Children
The Effect of Informative Animated Videos Watched Before Surgery on Anxiety and Fear in Children and Their Mothers
It is important to prepare children and their mothers psychologically for surgery. There are many initiatives to achieve this psychological preparation, including interactive educational booklets for children and their families…
- Trial name
- NCT07131982
- Testing
- Informative Animated Video to be Viewed with Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Goiter
Is the Use of Drain for Thyroid Surgery Realistic?
Background : The use of suction drains in thyroid surgery is common practice in order to avoid haematoma or seroma, as well as to identify promptly the onset of haemorrhaging that might compromise the patient's airway.
- Trial name
- NCT01771523
- Testing
- Thyroidectomy, use of drain
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Maltepe University
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