Clinical trials: Surgical Condition
Obesity
Surgical Treatment for Morbid Obesity by Sleeve Gastrectomy Versus Gastric Bypass
The aim of this study is to assess that the sleeve gastrectomy can improve the risk benefit than the gastric bypass
- Trial name
- SLEEVE (NCT00722995)
- Testing
- Sleeve gastrectomy, Gastric Bypass
- Where
- France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Caregiver, Lobectomy Patient
Physical Activity Intervention Before and After Surgery in Older Adults With Lung Cancer and Their Family Caregivers
This trial studies whether a telephone-based physical activity intervention before and after lung cancer surgery can be provided to older patients and their caregivers.
- Conditions
- Caregiver, Lobectomy Patient, Lung Carcinoid Tumor, Lung Non-Small Cell Carcinoma
- Trial name
- NCT04085081
- Testing
- E-mail, Exercise Intervention, Quality-of-Life Assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Operative Hemorrhage
Intrauterine Use of FloSeal: Is it Safe and Useful?
When having certain types of outpatient surgery inside the uterine cavity some women experience heavy bleeding. The only method presently available for controlling such bleeding, short of removing the uterus, involves the…
- Trial name
- NCT01746628
- Testing
- Hysterectomy with FloSeal
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- David L Zisow MD LLC
Pain, Pain Management
Ultrasound-guided Interscalene Block Versus Infraspinatus-Teres Minor Plane Block in Shoulder Arthroscopy
This study aims to compare the efficacy and safety of ultrasound-guided Interscalene block (ISB) versus Infraspinatus-Teres minor (ITM) interfacial plane block in shoulder arthroscopic surgery.
- Conditions
- Pain, Pain Management, Pain Management in Postoperative Care
- Trial name
- (ISB)-(ITM) (NCT07016386)
- Testing
- Group A: will receive an ultrasound-guided interscalene block (ISB), Group B:will receive an ultrasound-guided infraspinatus-teres minor (ITM) interfacial plane block
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Morbid Obesity, Overweight
Pharmacokinetics in Morbid Obesity After Bariatric Surgery
Morbid obesity (MO) is associated with several disorders such as hypertension, type 2 diabetes, dyslipemia and degenerative arthropathy that require pharmacological treatment.
- Trial name
- FAROBE/1 (NCT01086722)
- Testing
- "karolinska cocktail"
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Fundacion IMIM
Furcation Defects, Periodontal Diseases
Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST)
Teeth with furcation grade III defects will be treated with open flap debridement, with or without osteoplasty. The study is designed to examine the effect of osteoplasty in the treatment of teeth with furcation grade III defects…
- Trial name
- FURC-III-OST (NCT04017429)
- Testing
- Open flap debridement with osteoplasty, Open flap debridement without osteoplasty
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oslo
Scars
A Randomized Split Scar Study of Suture Safe Treatment of Surgical Wounds to Minimize Scaring
The purpose of this study is to evaluate the effect SutureSafe dressings have on reducing scarring from an incision following an elective abdominoplasty (tummy tuck) procedure.
- Trial name
- NCT02620475
- Testing
- SutureSafe
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Diabetes, Weightloss
The WISE (Weightloss Intervention Surgical Effects) Brain Study
This study is being done to learn about the changes that weight loss causes on brain function, memory and thinking ability in adults. The study does NOT cover any costs associated with bariatric surgery.
- Trial name
- WISEBrain (NCT02137070)
- Testing
- Bariatric Surgery Candidates, Non surgical/Community volunteers
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Florida
Gastrointestinal Stromal Tumors, Metastasis
Salvage Surgery for Patients With Metastatic GIST With Rego
Some researches have shown surgery may acquire progression-free (PFS) benefit for selected patients with metastatic gastrointestinal stromal tumor (GIST) who received first-line imatinib and second-line sunitinib.
- Conditions
- Gastrointestinal Stromal Tumors, Metastasis, Disease Progression
- Trial name
- NCT04343456
- Testing
- Salvage surgery with massive debulking
- Where
- Taiwan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Free Air in Abdomen
Point of Care Ultrasound for Diagnosis of Abdominal Free Air
This study evaluates the ability of ultrasound to identify intraperitoneal free air. The study will consist of blinded review of abdominal ultrasound images of patients before and after laparoscopic surgery, a procedure which…
- Trial name
- NCT03719872
- Testing
- Pre-Operative Transabdominal Ultrasound, Post-Operative Transabdominal Ultrasound
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Blehar
Pain, Pain Management
Evaluating The Efficacy Of Pecs II Blockade Compared To Local Anesthetic Infiltration In Controlling Postoperative Pain In Patients Undergoing Oncologic Breast Surgery Under Opioid Free/Sparing Anesthesia.
Breast cancer is the malignant neoplasm with the highest incidence in women in Brazil, with the exception of non-melanoma skin tumors.
- Conditions
- Pain, Pain Management, Anesthesia
- Trial name
- pain (NCT06889870)
- Testing
- Pectoral Nerve Block, Local Anesthesia
- Where
- Brazil
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas de Minas Gerais
Postoperative Pain, Acute
Comparison of the Effects of Tenoxicam and Paracetamol on Postoperative Pain
Postoperative pain is generally caused by inflammation and oedema related to tissue trauma. Surgical tissue trauma is caused by many factors such as cotery-related burns, surgical incisions, dissections, and instrumental…
- Trial name
- NCT05508451
- Testing
- Double jaw surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Malnutrition
Prospective Evaluation of NOTES (Natural Orifice Translumenal Endoscopic Surgery) PEG "Rescue"
The purpose of this study is to determine: 1. Utility of urgent upper endoscopy in setting of dislodges (percutaneous endoscopic gastrostomy) PEG tube. 2.
- Trial name
- PEGRescue (NCT01119040)
- Testing
- Natural Orifice Translumenal Endoscopic Surgery
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Post-Operative Cognitive Decline in Older Adults, Post-operative Cognitive Decline
Post-operative Cognitive Decline After Ambulatory Cataract Surgery in the Elderly Population
Postoperative cognitive decline is a recognized complication following anesthesia and surgery in older adults; however, its incidence after ambulatory cataract surgery performed under sedation is not well understood.
- Conditions
- Post-Operative Cognitive Decline in Older Adults, Post-operative Cognitive Decline, Perioperative Neurocognitive Disorders, Cataract Surgery Anesthesia
- Trial name
- NCT07714174
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Diabetes Mellitus, Ketoacidosis
Expected Normal Ketone Values After Very Low and Bariatric Surgery
The investigators propose a multicenter prospective study in patients undergoing either an elective bariatric procedure or an elective benign procedure, including laparoscopic/open cholecystectomy, laparoscopic/open hiatus hernia…
- Trial name
- NCT05442918
- Where
- Australia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne
Atherosclerosis, Periodontitis
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis.
A randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with periodontitis and without any cardiovascular disease.
- Trial name
- NCT05906797
- Testing
- Non-surgical periodontal treatment by Q-SI, Non surgical periodontal debridement using MINST approach
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Catania
Tooth Diseases, Tooth Wear
Effects of Antibiotic Prophylaxis on the Healing Parameters Following Surgical Crown Lengthening
The goal of this clinical trial is to test the effects of prophylactic antibiotics in healthy individuals who are in need of surgical crown lengthening.
- Trial name
- SCLABP (NCT05925179)
- Testing
- Surgical crown lengthening, Augmentin
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Biruni University
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
Degenerative Spine Diseases, Surgical Wound
Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)
The randomized controlled study which compare the efficacy outcomes (reducing blood loss and drainage output in patients) in patients undergoing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and…
- Trial name
- NCT06427850
- Testing
- Tranexamic acid, Normal saline
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Thanawan Longsuwan
Symptomatic Cervical Disc Disease
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease…
- Trial name
- SMART (NCT04012996)
- Testing
- prodisc C SK and/or Vivo, Mobi-C Cervical Disc
- Where
- 30 sites in United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Centinel Spine
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