Clinical trials: Surgical Hemostasis
Hemostasis, Surgical Blood Loss
Hemocoll, Avitene, or Bone Wax for Cancellous Bone Bleeding After Single-Ray Amputation
This is a multicentre, prospective, three-arm, parallel-group randomized controlled superiority trial evaluating fibrillar Type-I collagen haemostat (Hemocoll®) FTC, Avitene™ Microfibrillar Collagen Hemostat (MCH), and…
- Conditions
- Hemostasis, Surgical Blood Loss, Amputation Stump, Hemorrhage
- Trial name
- CANHAEM-Ray (NCT07788846)
- Testing
- Hemocoll® Fibrillar type-I collagen haemostat, Bone wax, Avitene™ Microfibrillar Collagen Hemostat
- Where
- 3 sites in India
- Volunteers
- 135 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Intraoperative Complications, Intraoperative Bleeding
Ostene in Thoracolumbar Decompression and Fusion Evaluated With VIBE
In spine surgery, it is important to try to minimize bleeding. In particular, spine surgery often involves inserting hardware into bone, and/or removing bone in the spine.
- Conditions
- Intraoperative Complications, Intraoperative Bleeding, Intraoperative Blood Loss, Hemostasis
- Trial name
- Ostene VIBe (NCT06450834)
- Testing
- Ostene
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- University of Maryland, Baltimore
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Spinal Tumor, Spinal Injury
Study of Collagen-Based Thrombin Hemostat for the Control of Bleeding in Spinal Surgery
This clinical trial evaluates the effectiveness and safety of a collagen-based hemostatic agent containing thrombin in patients undergoing spinal surgery.
- Conditions
- Spinal Tumor, Spinal Injury, Hemostasis, Spinal Stenosis
- Trial name
- NCT07354178
- Testing
- CollaStat®, Floseal®
- Where
- 3 sites in South Korea
- Volunteers
- 130 people
- Sponsor
- DALIM TISSEN Co., Ltd.
Surgical Hemostasis
Comparative Study Between the Effect of Dexmedetomidine ,Midazolam or Bupivacaine Packing During FESS on Surgical Field Visualization
The goal of this interventional study is to compare the nasal packing with dexmedetomidine .midazolam or bupivacaine on surgical field visualization during FESS .
- Trial name
- FESS (Function (NCT07013955)
- Testing
- Saline, Dexmedetomidine, Midazolam
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Minia University
Surgical Hemostasis
Safety and Efficacy of Topical Recombinant Human Thrombin(rhThrombin) for Surgical Hemostasis
A multicenter, stratified randomized, double-blind, placebo-controlled, phase 3 clinical trial.
- Trial name
- NCT04459871
- Testing
- recombinant human Thrombin(CHO cell)
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Liver Transplantation, Thrombin
Thrombin Generation in Liver Transplant Surgery
This is a prospective observational study of 100 patients undergoing liver transplantation at a single centre. Thrombin generation and kinetics will be assessed using a novel point-of-care device, and compared to conventional…
- Conditions
- Liver Transplantation, Thrombin, Hemostasis, Surgical, Blood Coagulation Disorder Due to Liver Disease
- Trial name
- NCT04762550
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Hemostasis, Surgical
The Safety and Effectiveness of PROCRIT (Epoetin Alfa) in Patients Undergoing Elective Major Abdominal and/or Pelvic Surgery
The primary purpose of the study is to compare the effect of perioperative (the time period describing the duration of a participants surgical procedure) administration of PROCRIT to that of Standard of Care (SOC) on the…
- Trial name
- NCT00350519
- Testing
- Epoetin alfa, Standard of Care
- Volunteers
- 37 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Blood Loss, Surgical, Hemostasis
OSHES - Observational Study on Hemostasis in Surgery (TC-022-IT)
OSHES (= Observational Study on Hemostasis in Surgery) is a non interventional register settled in Italy with the purpose of collecting data on 800 patients intra-operatively treated with hemostatic supporting agents/techniques…
- Trial name
- NCT00279383
- Testing
- Fibrinogen (human) + thrombin (human) (TachoSil)
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- Nycomed
Surgical Hemostasis
Study of Recombinant Human Thrombin for Bleeding During Surgery
The purpose of this study is to determine whether recombinant human Thrombin (rhThrombin) is effective in stopping bleeding during surgery, in comparison with bovine thrombin.
- Trial name
- NCT00245336
- Testing
- rThrombin, bovine thrombin
- Where
- 29 sites in United States
- Volunteers
- 401 people
- Sponsor
- ZymoGenetics
Surgical Hemostasis
Study of Recombinant Human Thrombin for Bleeding During Autologous Skin Grafting
The purpose of this study is to evaluate whether rThrombin is safe when used for controlling bleeding during skin graft surgery.
- Trial name
- NCT00371215
- Testing
- rThrombin
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- ZymoGenetics
Hemostasis,Surgical
Hemostatic Closure of Femoral Artery Access Site, Using the QuickClose
The QuickClose study is a prospective, non-randomized study, to evaluate the safety and efficacy of the QuickClose device using two different dose types of heat exposure.
- Trial name
- NCT00507013
- Testing
- QuickClose device
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- CardioDex