Clinical trials: Surgical Incision
Surgical Site Infection
Skin Staples vs Polypropylene in Elective Laparotomy
Surgical site infection (SSI) is one of the most common postoperative complications following elective laparotomy and contributes significantly to patient morbidity, prolonged hospital stay, and increased healthcare costs.
- Trial name
- NCT07781878
- Testing
- Skin staples, Polypropylene skin suture
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Surgical Site Infection, Surgical Wound Infection
Floraseal Versus Iodine Impregnated Adhesive Drapes
Infection after total joint arthroplasty can have devastating consequences. Adhesive drapes have been traditionally used at our institution to help reduce the risk of wound contamination and infection by superficial skin flora.
- Trial name
- NCT03466489
- Testing
- Floraseal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Infection, Surgical Site
Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study
Patients randomly aligned in 2 groups.Vicryl plus sutures were used in group 1 for closing subperiostal flaps after dental implant surgeries and vicryl sutures were used in group 2.
- Trial name
- NCT03659344
- Testing
- Vicryl plus
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Incisional Hernia/Prevention and Control, Surgical Site Infection (SSI)
Comparison of Small-bite Versus Conventional Midline Fascial Closure in Abdominal Surgeries
This study investigates how different incision and fascial closure (suture) techniques used in abdominal surgery are associated with the development of incisional hernia, a common long-term complication after laparotomy.
- Trial name
- NCT07340918
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Hypertrophic Surgical Scar, Medical Adhesive Related Skin Injury
Surgical Dressing Study Comparing SYLKE vs Other Common Incisional Dressings Following Abdominoplasty/Panniculectomy Patients
Include primary, secondary, and exploratory objectives. Primary Goal: To compare the effects of a silk fibroin-based dressing versus standard postoperative dressings on scar quality.
- Trial name
- NCT07878390
- Testing
- SYLKE, Dermabond Prineo, Paper Tape
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Colorectal Cancer
Efficacy of Single Incision (Embryonic NOTES) Laparoscopic Colorectal Surgery
Laparoscopic colon surgery has been performed widely. As a minimal invasive approach, single incision (Embryonic NOTES) colon surgery has been attempted.
- Trial name
- NCT01269060
- Testing
- Single Incision Laparoscopic Surgery
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Cesarean Section, Infection
Trial Comparing the Optimal Timing of Antibiotic Prophylaxis at the Time of Cesarean Delivery
The purpose of this study is to evaluate the rates of maternal and neonatal infectious morbidity in gravid patients undergoing cesarean delivery.
- Trial name
- NCT00811603
- Testing
- Cefazolin (Timing of Antibiotic Prophylaxis)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Transcutaneous Electric Nerve Stimulation
The Pain Intensity of the Patients Who Had Undergone Abdominal Surgery With a Midline Incision
The purpose of this study is to determine the effects of transcutaneous electrical nerve stimulation (TENS) and transcutaneous acupoint electrical stimulation (TAES) on pain and analgesic drug consumption in patients who had…
- Trial name
- NCT03762486
- Testing
- TENS, TAES
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yuksek Ihtisas University
Healing Surgical Wounds
Comparative Evaluation of Osseous Resection by Piezoelectric Device Versus Conventional Rotary Instruments
The aim of this study is to comparatively evaluate changes in periodontal healing, surgical time required and postoperative morbidity observed in patients undergoing osseous resection in crown lengthening procedure with…
- Trial name
- NCT03916653
- Testing
- osseous resection using piezoelectric device in surgical crown lengthening, Osseous resection using conventional rotary instruments in surgical crown lengthening
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Dermatochalasis, Ptosis, Eyelid
A Comparison of the Effect of Suture Material on Blepharoplasty Incision
The objective is to compare the effect of suture material on blepharoplasty incision. Outcomes of blepharoplasty scar and/or cosmesis will be compared between plain gut and polypropylene suture.
- Trial name
- NCT04585217
- Testing
- Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Efficacy Povidone Soaked Suture in Reducing Surgical Site Infection
Title: Povidone-soaked Sutures Versus Ordinary Sutures for Reducing Surgical Site Infection
To determine efficacy of using 3 minutes povidone-soaked suture in reducing surgical site infection during wound closure in elective surgery.
- Trial name
- NCT05090176
- Testing
- povidone-soaked suture, ordinary suture
- Where
- Malaysia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Cesarean Section Complications, Uterine Bleeding
Surgical Incision Closure Method to Prevent Niche Formation After Cesarean Section- Randomized Controlled Trial
In the last decade we have been exposed to the complication of a caesarean section called a "niche". A niche is an anaerobic defect in the location of the cesarean section, which represents the discontinuity of the endometrium…
- Trial name
- NCT04766073
- Testing
- Niche prevention suture
- Where
- Israel
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Wound Healing
Efficacy of Early Postoperative ON101 Application for Lower-extremity Fracture Incisions: a Prospective Evaluator-blinded Controlled Study of Scar Quality and Digital-clinical Concordance
Background: Postoperative scars after lower-extremity fracture fixation endure high tension, where excessive scarring can restrict periarticular mobility.
- Trial name
- ON101 Efficacy (NCT07854470)
- Testing
- ON101
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LIN Kai-Cheng
Total Joint Arthroplasty, Risk Reduction
Arthroplasty and Modifiable Risk Factors
Hip and knee total joint arthroplasty are one of the most frequently performed surgery worldwide. However, prosthetic joint infection remains a devastating complication of them, associated with severe morbidity, increased…
- Conditions
- Total Joint Arthroplasty, Risk Reduction, Surgical Site Infection, Prosthetic-joint Infection
- Trial name
- NCT05399186
- Testing
- Early preoperative assessment and optimization
- Where
- Iceland
- Volunteers
- 1,484 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Cesarean Section, Wound Complications
Cesarean Trial of Staples vs. Sutures
To determine whether the rate of wound complications differs based on method of closure of skin incision (staples vs. suture) after cesarean delivery.
- Conditions
- Cesarean Section, Wound Complications, Patient Satisfaction, Pain Measurement
- Trial name
- CROSS (NCT01211600)
- Testing
- Staples, Suture
- Where
- 2 sites in United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Obesity, Surgical Site Infections
Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery
The investigators aim to show that single use negative pressure dressings can decrease the rate of wound complications in obese women (BMI > 40 kg/m2) undergoing cesarean delivery at a tertiary medical center by randomizing women…
- Conditions
- Obesity, Surgical Site Infections, Wound Complications, Complications; Cesarean Section
- Trial name
- NCT02799667
- Testing
- Standard Dressing, Negative Pressure Wound Therapy Dressing
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Temporal Wasting
The Effect of Temporal Muscle Suspension of Temporal Hollowing
The primary objective is to identify which patients undergoing a traditional pterional approach with 2 different surgical techniques for TMS (Temporal Muscle Suspension) will develop TH (Temporal Hollowing.
- Trial name
- TMS (NCT03324516)
- Testing
- Re-Suspension of the temporal muscle after a craniotomy., Traditional re-suspension of the temporal muscle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Peyronie's Disease
Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's
The purpose of this study is to compare key clinical outcomes of collagenase clostridium histolyticum injections versus surgery for the management of Peyronie's Disease.
- Trial name
- iSCRIP (NCT04786106)
- Testing
- Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex] (CCH), Penile Plication Surgery, Incision and Grafting (I&G) Surgery
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Surgical Wound
Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.
When patients undergo neck dissection surgeries, the current standard of care is to close the skin layer with either metal staples, which are removed a few days post-operatively, or with sutures, which can be absorbable or…
- Trial name
- NCT02936063
- Testing
- Surgical staples, Subcuticular sutures
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Clinical and Radiographic Effect, Thick-gingiva
Clinical and Radiographic Evaluation of a Cross-shaped Incision Technique
To evaluate a cross-shaped incision technique to thick-gingiva and thin-gingiva patients treated with implant-supported fixed prosthesis.
- Conditions
- Clinical and Radiographic Effect, Thick-gingiva, Implant, Thin Gingiva
- Trial name
- NCT04706078
- Testing
- The biotype of gingival
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Wen Luo