Clinical trials: Surgical Injury
Bladder Injury, Complications; Cesarean Section
Cystoinflation to Prevent Bladder Injury in Obstetrics and Gynaecology Surgery
Part1:The healthy pregnant women with previous operative deliveries admitted for elective C-section will be counselled and conditioned informed consent will be taken to be included in either study group if dense pelvic adhesions…
- Conditions
- Bladder Injury, Complications; Cesarean Section, Adhesions Pelvic
- Trial name
- NCT04302545
- Testing
- Cystoinflation
- Where
- Pakistan
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Shazia Saaqib
Surgical Site Infection
Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis
Primary Hypothesis: chlorhexidine gluconate alcohol skin antiseptic preparation is superior to povidone-iodine scrub and paint skin antiseptic preparation for prevention of cesarean related surgical site infection.
- Trial name
- CAPICA (NCT02202577)
- Testing
- Chlorhexidine - Isopropyl alcohol, Povidone-Iodine Scrub and Paint
- Where
- United States
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Non-melanoma Skin Cancer
Healing Effects of HP802-247 Versus Antibiotic Ointment in Mohs Micrographic Surgery Patients
This study compares HP802-247 versus an antibiotic ointment for healing the wound after Mohs surgery.
- Trial name
- NCT01359735
- Testing
- HP802-247, Bacitracin Ointment
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Healthpoint
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Hypertrophic
Investigation of a Novel Silicone Dressing to Maximize the Outcomes of Scar Revision Procedures (IMPROVE)
Neodyne has developed an investigational dressing for post-operative incision care. Neodyne is conducting this research to study whether the investigational dressing, called the Neodyne Dressing, can minimize scar formation in a…
- Trial name
- IMPROVE (NCT01430130)
- Testing
- embrace device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Neodyne Biosciences, Inc.
Hip Fracture, Myocardial Ischemia
Pilot Study of Atorvastatin for Orthopedic Surgery Patients
Up to 35% of hip fracture patients have been shown to experience heart injury after surgery, and as many as 10% have a heart attack or die in the three months after surgery.
- Conditions
- Hip Fracture, Myocardial Ischemia, Inflammation
- Trial name
- POST-OP Pilot (NCT02197065)
- Testing
- Atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Late Effects of Surgery, Staphylococcus Aureus
Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery
This investigation is a prospective, open-label pharmacokinetic study of daptomycin prophylaxis in patients undergoing coronary artery bypass graft surgery without valvular replacement.
- Conditions
- Late Effects of Surgery, Staphylococcus Aureus, Surgical Site Infection
- Trial name
- NCT00701636
- Testing
- daptomycin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Rupture, Venous Thromboembolism
Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture
This prospective randomized study aims to determine whether intermittent pneumatic compression (IPC), 75 patients, beneath functional bracing compared to treatment-as-usual in plaster cast, 75 patients, can reduce the Venous…
- Conditions
- Rupture, Venous Thromboembolism, Venous Thrombosis, Surgical Wound Infection
- Trial name
- NCT01317160
- Testing
- Intermittent pneumatic compression (IPC)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska University Hospital
Quadratus Lumborum Block, Surgical Wound Infiltration
Surgeon Infiltration QL Block Comparison
The purpose of this study is to learn if using a Quadratus Lumborum (QL) plane injection technique (also called a "nerve block") that numbs the nerves going to the abdominal area improve pain control after surgery compared to…
- Trial name
- NCT03496610
- Testing
- Liposomal Bupivicaine, QL Block
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Duke University
Surgical Incisions
Prineo (Dermabond Protape) Versus Sutures for Full-thickness Surgical Incisions
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 subjects with full thickness surgical incisions.
- Trial name
- NCT00557947
- Testing
- Suture, Dermabond Protape (Prineo)
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Fatigue
Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord
Electrosurgery is used in virtually every laparoscopic operation performed. Capacitive coupling is a common electrosurgery complication.
- Trial name
- NCT01707095
- Testing
- Unbundling of cords, Bundling of cords
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Supracondylar Humerus Fracture, Post Operative Wound Infection
Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
The aim of this study is to determine if antibiotics affect the outcome after percutaneous surgery for pediatric supracondylar humerus fractures.
- Trial name
- NCT03261830
- Testing
- Cefazolin, Clindamycin, Saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Sumit Gupta
Cesarean Section
Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples
Women who have a cesarean delivery have a surgical incision on their abdomen (belly). The usual way to close this opening is with metal surgical staples.
- Trial name
- NCT00524511
- Testing
- Surgical skin staples, Dermabond
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Massachusetts, Worcester
Posttraumatic Stress Disorders, Combat Disorders
Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders
In comparison to the general population, U.S. military and Veterans are at an increased risk for developing both substance use disorders (SUD) and Post Traumatic Stress Disorder (PTSD).
- Conditions
- Posttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug Dependence
- Trial name
- COPE (NCT01338506)
- Testing
- Concurrent Treatment with Prolonged Exposure (COPE)
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Medical University of South Carolina
Surgical Site Infection
Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections
The purpose of this study was to compare the rate of surgical site infections in patients randomized to Irrisept versus SoC, who had an open abdominal laparotomy for abdominal trauma or acute surgical abdomen.
- Trial name
- NCT02255487
- Testing
- IrriSept System, No Intervention - Standard of Care (SoC) only
- Where
- 17 sites in United States
- Volunteers
- 627 people
- Sponsor
- Irrimax Corporation
Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants
Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if photodynamic therapy has an effect on bacterial skin colonization and decrease number of…
- Conditions
- Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection
- Trial name
- PHOMIC (NCT04067843)
- Testing
- Photodynamic treatment
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Endometritis, Wound Infection
Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
The Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) study is a large pragmatic multi-center randomized clinical trial designed to evaluate the comparative effectiveness and safety of azithromycin-based extended-spectrum…
- Conditions
- Endometritis, Wound Infection, Abscess, Surgical Site Infection
- Trial name
- C/SOAP (NCT01235546)
- Testing
- Azithromycin and standard of care
- Where
- 9 sites in United States
- Volunteers
- 2,013 people
- Sponsor
- Alan Tita
Kidney Injury
Prevention of Acute Kidney Injury in Cardiac Surgery Patients
Acute kidney injury (AKI) has no uniform criteria, but is commonly defined as an increase in serum creatinine concentration by at least 25% from baseline.
- Trial name
- NCT00921518
- Testing
- Sodium Bicarbonate
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Community Medical Center, Scranton, PA
Post Surgical Incisions From Abdominoplasty Procedures
Clinical Evaluation of the GLYDe Dressing for Post-surgical Incision Care
This study will evaluate a new dressing to be used for post-incision care for abdominoplasty patients. The hypothesis is that this dressing will minimize scar formation.
- Trial name
- Mona Lisa (NCT00766727)
- Testing
- GLYDe Dressing
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Neodyne Biosciences, Inc.
Morbid Obesity, Bariatric Surgery Candidate
Transversus Abdominis Plane (TAP) Block Using Liposomal Bupivacaine in Metabolic and Bariatric Surgery Patients
To investigate if laparoscopic Transversus Abdominis Plane (TAP) block using plain bupivacaine is equivalent to using liposomal bupivacaine in patients undergoing metabolic and bariatric surgery.
- Trial name
- TAP (NCT05537883)
- Testing
- Liposomal bupivacaine, Bupivacaine Injection
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Wake Forest University Health Sciences