Clinical trials: Surgical Mesh
Pain, Dyspareunia
Randomized Trial of Interrupted Versus Continuous Vaginal Closure of Anterior Repair With Mesh
Vaginal prolapse is a common condition that is treated with surgical correction. Recently surgeons have been using mesh to augment the repair of vaginal prolapse.
- Conditions
- Pain, Dyspareunia, Surgical Mesh
- Trial name
- NCT00676000
- Testing
- Interrupted vaginal closure, Continuous vaginal closure
- Volunteers
- 350 people
- Sponsor
- Brigham and Women's Hospital
Colorectal Cancer, Wound Infection
Comparing PP and PVDF Meshes in Midline Laparotomy Closure for High-risk Colorectal Surgery. Impact on Incisional Hernia and Surgical Wound Infection.
In the latest guidelines for abdominal wall closure in emergency surgery published in the World Journal of Emergency Surgery (WJES) in 2023, no specific recommendations are made in this regard.
- Conditions
- Colorectal Cancer, Wound Infection, Hernia Incisional
- Trial name
- PROFIMESH (NCT06220045)
- Testing
- Polyvinylidene fluoride mesh, Prophylactic polypropylene mesh
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
MeSH Heading Cardiac Surgical Procedures, Tree Number E04.100.376
Gastrointestinal Microcirculation During Cardiopulmonary Bypass
O2C is a diagnostic device for non-invasive determination of oxygen supply in microcirculation of blood perfused tissues. The optical sensor is easy to handle and guarantees reproducible examinations of local oxygen supply of…
- Conditions
- MeSH Heading Cardiac Surgical Procedures, Tree Number E04.100.376, Tree Number E04.928.220
- Trial name
- NCT01425931
- Testing
- Heart Lung machine
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Apical Prolapse, Sacrocolpopexy
Evaluation of the Use of Synthetic Glue for Mesh Fixation in Laparoscopic Sacrocolpopexy
The aim of the study is to evaluate the effect of cyanoacrylate adhesive in laparoscopic sacrocolpopexy, which is the gold standard treatment for apical prolapse.
- Conditions
- Apical Prolapse, Sacrocolpopexy, Glue Fixation
- Trial name
- LSCGlue (NCT06872983)
- Testing
- cyanoacrylate tissue adhesive beside sutures, Suture
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Brno University Hospital
Ventral Hernia
A Comparison of the Outcomes in Fortiva and Strattice Mesh
A comparison of ventral hernia repair with Strattice and Fortiva mesh.Primary The study team aims to determine the hernia recurrence rates for RTI Surgical biologic mesh (Fortiva) compared to Strattice.
- Trial name
- NCT05572021
- Testing
- Prospective Ventral Hernia Repair with Fortiva, RetroSpective Ventral Hernia Repair with Strattice
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Wake Forest University Health Sciences
Pelvic Organ Prolapse (POP), Synthetic Mesh
Safety and Performance of a Pelvic Floor Mesh Implant for Laparoscopic Sacrocolpopexy (ProGYNious)
The purpose of this clinical investigation is to collect clinical data about the ProGYNious Mesh based on a prospective clinical investigation.
- Conditions
- Pelvic Organ Prolapse (POP), Synthetic Mesh, Laparoscopic Surgery, Gynecologic Laparoscopic Surgery
- Trial name
- ProGYNious (NCT07497321)
- Testing
- Surgical mesh for pelvic organ prolapse repair (ProGYNious)
- Where
- 5 sites in Austria, Germany
- Volunteers
- 100 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Unrecognized Condition
Different Surgical Techniques Used for Prolapse Repair in Elderly Patient
The investigator aimed to compare various pelvic floor repairs in female aged from 70 to 80 years old, to see which procedure in terms of treatment-related complications of SCP, VMR and NTR by comparing the operative and…
- Trial name
- NCT03445442
- Testing
- SCP, NTR, VMR
- Volunteers
- 214 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Ventral Hernia Repair, Hernia Abdominal Wall
Onlay vs. Sublay Mesh Hernioplasty for Primary Ventral Hernia
This randomized controlled trial will compare the surgical outcomes of onlay mesh hernioplasty versus sublay mesh hernioplasty in patients with primary ventral wall hernias.
- Trial name
- NCT07896278
- Testing
- Onlay Mesh Hernioplasty, Sublay Mesh Hernioplasty
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Provincial Headquarter Teaching Hospital Gilgit
Uterine Prolapse, Vault Prolapse
Laparoscopic Sacral Colpopexy Versus Modified Total Pelvic Floor Reconstructive Surgery for Apical Prolapse Stage III-IV
Pelvic Organ prolapse (a feeling of bulge in the vagina) may cause some distressing symptoms such as loss of control of the bowel or bladder, and may also cause problems with patient's sex life. The primary treatment is surgery.
- Trial name
- NCT01762384
- Testing
- LSC, modified PFRS, "Gynemesh"
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Ventral Hernia
Prophylactic Mesh to Reduce The Incidence of Ventral Hernia
The incidence of ventral hernias has remained inappropriately high. Any innovation in order to reduce this incidence would be simply cost-effective.
- Trial name
- NCT01788826
- Testing
- Prophylactic mesh, No prophylactic mesh closure
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- Henares University Hospital
Inguinal Hernia Unilateral
STAPLES VERSUS SUTURES FOR MESH FIXATION IN LICHTENSTEIN HERNIOPLASTY: A RANDOMIZED CONTROLLED TRIAL EVALUATING POSTOPERATIVE OUTCOMES IN INGUINAL HERNIA PATIENTS
The study is aimed at comparing postoperative complications between two different techniques of mesh fixation in lichtenstein inguinal hernia repair.
- Trial name
- NCT07627425
- Testing
- Mesh fixation with Staples, Mesh Fixation with Sutures
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Huzaif Saeed Khan
Liver Cirrhosis
Thoracoscopic Mesh Repair of Diaphragmatic Defects for Hepatic Hydrothorax
The management of refractory hepatic hydrothorax is challenging and usually unsuccessful. The study will discuss the perioperative treatment, effectiveness, and morphology of diaphragmatic defects of hepatic hydrothorax in…
- Trial name
- NCT02508688
- Testing
- thoracoscopic diaphragmatic repair
- Volunteers
- 63 people
- Sponsor
- National Taiwan University Hospital
Inguinal Hernia
PMCF Study of LiquiBand FIX8® OHMF Device
Study to evaluate the safety and performance of LiquiBand FIX8® Open Hernia Mesh Fixation Device.
- Trial name
- LBF8-Open (NCT04059640)
- Testing
- LiquiBand FIX8 Open Hernia Mesh Fixation Device
- Where
- 3 sites in United Kingdom
- Volunteers
- 109 people
- Sponsor
- Advanced Medical Solutions Ltd.
Incisional Hernia After Diverting Stoma Closure
Mesh Reinforcement During Temporary Stoma Closure After Sphincter-Saving Rectal Cancer Surgery
This study aim to assess long-term results of an incisional hernia-prophylactic mesh placement during stoma reversal after total mesorectal excision (TME) for rectal cancer
- Trial name
- MEMBO (NCT02576184)
- Testing
- Biologic Mesh, Synthetic Mesh
- Where
- France
- Volunteers
- 381 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thyroid Gland Carcinoma, Thyroid Cancer
Effect of Polyglycolic Acid Mesh (Neoveil) in Thyroid Cancer Surgery
This study is a randomized controlled study to investigate the effect of "Polyglycolic Acid Mesh Sheet (NeoveilTM)" on the thyroid cancer surgery.
- Conditions
- Thyroid Gland Carcinoma, Thyroid Cancer, Thoracic Duct Leak
- Trial name
- NCT03510143
- Testing
- Neoveil (Polyglycolic Acid Mesh)
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Seoul National University Hospital
Hernia, Inguinal
PHS, Lichtenstein Mesh, and PerFixPlug for Primary Inguinal Hernia Repair - 3 Years Results
Three different techniques for the surgical repair of groin hernias are compared. Focus has been set on operation times, time to full return of functional abilities like walking in stairs etc, and if any technique has more…
- Trial name
- BOOP (NCT00580177)
- Testing
- Lichtenstein mesh, PerFix Plug®, Prolene® Hernia System
- Where
- Sweden
- Volunteers
- 472 people
- Sponsor
- Göteborg University
Hernia
Quantitative Sensory Testing and Analysis of Post Inguinal Hernia Surgery Pain
Increasing experience has identified post-herniorraphy chronic pain as an under-recognized and important complication. Nerve entrapment and injury are recognized as causes of such pain.
- Trial name
- NCT01534429
- Testing
- Quantitative Sensory Testing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Breast Cancer, Risk Reduction
Restore-B: A Trial Comparing Prepectoral Implant-based Breast Reconstruction With and Without Mesh
The goal of this feasibility randomised controlled clinical trial (RCT) is to compare mesh-assisted to no-mesh pre-pectoral implant based immediate breast reconstruction in women undergoing mastectomy for treatment of breast…
- Trial name
- NCT06112977
- Testing
- Prepectoral implant-based immediate breast reconstruction
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Oxford
Inguinal and Ventral Hernia Repair by Sublay, Underlay and IPOM Mesh Fixation
Effectiveness, Appropriateness and Safety of GLUTACK-Glubran Tiss 2 Surgical Glue Compared to GLUTACK-Glubran 2 Device System for Mesh Fastening in Laparoscopic and Robotic Hernia Surgery
This pre-market, prospective, randomized, non-inferiority clinical study was designed to evaluate the safety and performance/effectiveness of Glutack-Glubran® Tiss 2 system compared to Glutack-Glubran® used for mesh fixation in…
- Trial name
- AGluTHeMFix (NCT06462066)
- Testing
- Experimental medical device, Comparator medical device
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- GEM SRL
Valid MeSH Conditions
Textbook Outcomes in Urgent Appendectomy
A "textbook outcome" patient is defined as one whose surgical course is uneventful, with no complications, readmissions, or mortality.
- Trial name
- APPX_TEXTBOOK (NCT06765044)
- Volunteers
- 500 people
- Sponsor
- Hospital del Mar