Clinical trials: Surgical Oncology
Cancer
Care Pathways for Colorectal Cancer Surgery
EVALUATE THE CARE PROCESS AND THE QUALITY OF CARE FOR ADULT CANCER PATIENTS WHO ARE ADMITTED FOR COLORECTAL SURGERY
- Trial name
- CP4GICAN (NCT02965794)
- Testing
- Care pathways for colorectal cancer
- Where
- Belgium
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- European Pathway Association
Cancer Surgery, Elective Surgery
Virtual Group Prehabilitation Education (Surgery School) Feasibility Trial
One in four patients requiring planned major surgery have complications. Prehabilitation; which involves increasing physical activity, improving nutrition and supporting emotional well-being prior to surgery can reduce these…
- Conditions
- Cancer Surgery, Elective Surgery, Patient Education, Prehabilitation
- Trial name
- GoPREPARE (NCT07278622)
- Testing
- GoPREPARE
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Colorectal Cancer
Radiation Therapy Before Surgery Compared With Chemotherapy Plus Radiation After Surgery in Treating Patients With Rectal Cancer That Can Be Surgically Removed
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00003422
- Testing
- fluorouracil, leucovorin calcium, adjuvant therapy
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 1,800 people
- Sponsor
- Medical Research Council
Kidney Cancer
Monoclonal Antibody Therapy (Rencarex®) in Treating Patients Who Have Undergone Surgery for Non-metastatic Kidney Cancer
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.
- Trial name
- NCT00087022
- Testing
- girentuximab
- Where
- 56 sites in United States, Argentina and 2 more
- Volunteers
- 864 people
- Sponsor
- Heidelberg Pharma AG
Chemotherapy-induced Peripheral Neuropathy (CIPN), Gynecologic Cancers
Glove Compression for Chemotherapy-Induced Neuropathy
This study investigates whether wearing tight-fitting surgical gloves on the non-dominant hand could help prevent chemotherapy-induced peripheral neuropathy (CIPN) in women with gynecologic cancers treated with paclitaxel.
- Conditions
- Chemotherapy-induced Peripheral Neuropathy (CIPN), Gynecologic Cancers, Ovarian Cancer (OvCa), Endometrial Cancer
- Trial name
- NEURO-GLOVE (NCT07105553)
- Testing
- Surgical Glove Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital
Wound Complications, Wound Infection
A Study to Evaluate a Quality Improvement Intervention to Reduce Wound Separation Rates in Obese Gynecologic Oncology Service Patients Undergoing Abdominal Surgery
Approximately 500,000 surgical site infections occur annually in the US. These lead to worse patient quality of life, more outpatient and emergency room visits, readmissions and home services, with an estimated increase in costs…
- Conditions
- Wound Complications, Wound Infection, Wound Separation
- Trial name
- NCT02071251
- Testing
- Prospective wound complication protocol
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Washington University School of Medicine
Lung Cancer
Positron Emission Tomography in Predicting Response in Patients Who Are Undergoing Treatment With Pemetrexed Disodium and Cisplatin With or Without Surgery for Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
RATIONALE: Diagnostic procedures, such as positron emission tomography (PET), (done before, during, and after chemotherapy) may help doctors predict a patient's response to treatment and help plan the best treatment.
- Trial name
- NCT00227539
- Testing
- cisplatin, pemetrexed disodium, adjuvant therapy
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Washington
Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Head &Amp;Amp; Neck Squamous Cell Carcinoma
Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer
Delays between surgery and the initiation of post-operative radiotherapy (S-PORT) in head and neck cancer (HNC) patients are prevalent and associated with worse oncologic outcomes.
- Conditions
- Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Head &Amp;Amp; Neck Squamous Cell Carcinoma, Larynx Squamous Cell Carcinoma
- Trial name
- PRONTO-HN (NCT07180901)
- Testing
- Proactive Risk-Based Optimization and Notifications for Treatment and Outcomes (PRONTO)
- Where
- Canada
- Volunteers
- 85 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pancreatic Cancer
Resection of the Nerve Plexus on the Right Half of Celiac and SMA Associated With Extended Pancreatoduodenectomy in the Surgical Treatment for Adenocarcinoma of the Head of Pancreas
This study is performed to confirm whether resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy could improve survival and relieve pain of pancreatic cancer patients.
- Trial name
- NCT02514928
- Testing
- resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy, standard pancreatoduodenectomy
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Fudan University
Bladder Cancer, Urologic Cancer
Unmet Supportive Care Needs in Bladder Cancer Patients Undergoing Radical Cystectomy
Nowadays, high-quality cancer care is more than just diagnosis and treatment of cancer. Healthcare must respond to the specific needs of the patients to provide patient-centered care.
- Conditions
- Bladder Cancer, Urologic Cancer, Surgery
- Trial name
- NCT03307200
- Where
- 2 sites in Belgium
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ghent
Renal Cell Carcinoma
Residual Normal Renal Parenchymal and Tumor Volume in Tumor Surgeries
1. Calculation of the expected residual renal tissue volume using contrast CT in renal tumor patients and its effect on preoperative decision making 2.
- Trial name
- NCT04244136
- Testing
- contrast CT
- Volunteers
- 32 people
- Sponsor
- Assiut University
Pain, Decreased Lung Function
ThOracoscopic Wedge Resection Treated With Chest Tube Removal Intraoperatively
Chest tubes are used routinely although preliminary studies demonstrate the feasibility and safety of intraoperative chest drain removal. Previous studies are however either retrospective or mainly concerning benign disease.
- Conditions
- Pain, Decreased Lung Function, Delayed Discharge
- Trial name
- TOTTI (NCT02829736)
- Testing
- Intraoperative sealing test, Standard post-operative chest tube, Intraoperative chest tube removal
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Colon Cancer
Prehabilitation in Colorectal Cancer
Objectives To investigate the impact of tele-supervised prehabilitation on functional capacity in colon cancer patients undergoing colorectal resection for cancer and to evaluate the effects of prehabilitation on muscle strength…
- Trial name
- NCT03096951
- Testing
- Prehabilitation, Rehabilitation
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Smoking Cessation, Smoking Reduction
Preoperative Smoking Cessation in Patients Undergoing Surgery
Background: At present, effectively implementing smoking cessation programs in the health care system constitutes a major challenge. A unique opportunity to initiate smoking cessation focuses on smokers scheduled for surgery.
- Conditions
- Smoking Cessation, Smoking Reduction, Surgery--Complications, Surgery
- Trial name
- PORTICO (NCT05192837)
- Testing
- Intensive preoperative smoking cessation counselling
- Where
- Switzerland
- Volunteers
- 251 people
- Sponsor
- Luzerner Kantonsspital
Prostatic Neoplasms, Urinary Bladder Neoplasms
Impacts of Different Pressure Pneumoperitoneum on Myocardial and Pulmonary Injuries After Robot-assisted Surgery
This study is aimed to determine whether low- and standard-pressure pneumoperitoneum have different impacts on troponin T（TnT) level as well as pulmonary complications after prolonged robot-assisted surgeries in the Trendelenburg…
- Trial name
- NCT02600481
- Testing
- low-pressure pneumoperitoneum, standard-pressure pneumoperitoneum
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Huadong Hospital
Colo-rectal Cancer
Multicentric National Italian Analysis of Textbook Outcome in Colorectal Cancer Surgery
Colorectal cancer (CRC) is the third most common malignancy worldwide, with more than 1.9 million new cases reported annually. Survival among patients with CRC depends on several factors, including disease stage at diagnosis, the…
- Trial name
- ATOCCS (NCT07718919)
- Where
- Italy
- Volunteers
- 6,129 people
- Sponsor
- Academy of Applied Medical and Social Sciences, Poland
Malignant Glioma, Glioma
A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors
In this study subjects will be administered a single oral dose of Aminolevulinic Acid (ALA) prior to surgical resection of their brain tumor.
- Conditions
- Malignant Glioma, Glioma, Glioblastoma, Glioblastoma Multiforme
- Trial name
- NCT01351519
- Testing
- Aminolevulinic Acid
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- MultiCare Health System Research Institute
Breast Cancer Survivor
Self-Determination Theory-informed Occupational Therapy Program to Increase Physical Activity Among Survivors of Breast Cancer
We will evaluate a novel 8-week telehealth-delivered occupational therapy (OT) program among breast cancer survivors that seeks to promote engagement in aerobic physical activity (PA) and muscle strengthening exercise (MSE).
- Trial name
- SDOTS (NCT06671730)
- Testing
- 8-Week Telehealth-based Occupational Therapy Program
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Oklahoma
Chordoma of Spine, Surgery
A Prospective Study of Surgical Treatment Strategies for Chordoma
Chordoma is a rare but locally invasive cancer that arises from the embryonic notochord. Total resection is challenging in mobile spine because of the complex anatomy and bone invasion.
- Trial name
- NCT05707767
- Testing
- Resection surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Intravenous Lidocaine and Immunity
Impact of Intravenous Lidocaine During Colorectal Surgery on Pain and Immune Functions
This study evaluates the impact of intraoperative intravenous lidocaine administered during laparoscopic colorectal surgery on the intraoperative remifentanil consumption as well as postoperative pain and opioid requirements.
- Trial name
- NCT03410836
- Testing
- intravenous lidocaine (IVL)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
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