Clinical trials: Surgical Oncology
Lung Cancer (NSCLC)
Construction and Application Research of a Multidisciplinary Combined Exercise Management Program for Elderly Lung Cancer Patients After Surgery Based on Social Cognitive Theory
Informed Consent Form Protocol Title: Construction and Application Research of a Multidisciplinary Combined Exercise Management Program for Elderly Lung Cancer Patients After Surgery Based on Social Cognitive Theory Version…
- Trial name
- NCT07824778
- Testing
- Exercise Management for Elderly Lung Cancer Patients After Surgery Based on Social Cognitive Theory
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Sir Run Run Shaw Hospital
Breast Cancer, Anesthesia
Pain Control in Breast Surgery: Analgesia, Opioid Consumption and Inflammatory Response Evaluation
The serratus anterior muscle plane (SAM) block associated with pectoral nerve block type I (PEC I) may be a safe and effective alternative for the intraoperative of breast surgery, since there is evidence of pain reduction.
- Trial name
- NCT02647385
- Testing
- Block with lidocaine for SAM and PEC I block
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital Sirio-Libanes
Neuromuscular Blockade
Neuromuscular Blockade During Transurethral Resection of Bladder Cancer
Transurethral resection of the bladder tumor (TURB) for bladder tumor excision is the mainstream treatment. However, the beneficial effects of sugammadex after general anesthesia for TURB have not been thoroughly evaluated.
- Trial name
- NCT03039543
- Testing
- Rocuronium, Sugammadex
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Bundang Hospital
Breast Cancer Female
GENe EXpression After Regional or General ANesthesia in Patients Undergoing Breast Cancer Surgery
Breast cancer is the most commonly diagnosed cancer in females and the second leading cause of death from cancer in women. It was estimated that 2 million new cases have occurred in 2018 worldwide 1.
- Trial name
- GENEXAN (NCT03779685)
- Testing
- General anesthesia, Regional anesthesia
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Residual Tumor, Disease-free Survival
Laparoscopy for Primary Cytoreductive Surgery in Advanced Ovarian Cancer
To assess the feasibility, Residual Tumor, complication rate and survival of totally laparoscopic primary cytoreduction in carefully selected patients with Advanced Ovarian Cancer, compared with abdominal primary cytoreduction in…
- Conditions
- Residual Tumor, Disease-free Survival, Overall Survival
- Trial name
- NCT02980185
- Testing
- Laparoscopic primary cytoreduction
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Università degli Studi dell'Insubria
Colorectal Cancer
Follow-Up Care With or Without CEA Assessments in Patients Who Have Undergone Surgery for Stage II or Stage III Colorectal Cancer
RATIONALE: Diagnostic procedures, such as ultrasound, x-ray, colonoscopy, CT scan, and CEA assessment, may help monitor a patient's response to surgery.
- Trial name
- SURVEILLANCE (NCT00995202)
- Testing
- Standard Monitoring CEA, Intensive Monitoring CEA, Standard Monitoring Imagery
- Where
- 117 sites in Belgium, France and 1 more
- Volunteers
- 1,997 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Thrombosis, Venous
Comparative Analysis of Injectable Anticoagulants for Thromboprophylaxis Post Cancer-related Surgery
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common post-operative complication.
- Trial name
- NCT01444612
- Testing
- dalteparin, enoxaparin, fondaparinux
- Volunteers
- 4,068 people
- Sponsor
- GlaxoSmithKline
Thyroid Nodule
2-day Prophylactic Antibiotic is Effective in Transoral Endoscopic Thyroidectomy
In transoral thyroidectomy via vestibular approach (TOETVA), prophylactic antibiotic for 5~7 days is recommended for the clean-contaminated wound.
- Trial name
- NCT04268407
- Testing
- Amoxicillin Clavulanate
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Glioblastoma
Vebreltinib Combined With Temozolomide for Glioblastoma (GBM) After Surgery
The purpose of this study is to explore the effects of Vebreltinib in primary glioblastoma patients receiving a combination therapy of chemotherapy (temozolomidel) and MET-TKI.
- Trial name
- NCT06780592
- Testing
- Vebreltinib + Temozolomide, Temozolomide
- Volunteers
- 60 people
- Sponsor
- Huashan Hospital
Primary Malignant Melanoma of the Esophagus
Characteristics and Tumor Staging Proposal for Primary Malignant Melanoma of the Esophagus
Background: Primary malignant melanoma of the esophagus (PMME) is a malignant tumor originating from esophageal melanocytes with a poor prognosis.
- Trial name
- NCT06291753
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Sun Yat-sen University
Colorectal Cancer, Hepatobiliary Cancer
Exercise Preconditioning with Cancer Surgeries
Studies have shown that people who are more physically fit prior to surgery do better after surgery. For this reason, it may be helpful for people who are going to have abdominal surgery for cancer to exercise before surgery to…
- Conditions
- Colorectal Cancer, Hepatobiliary Cancer, Gynecologic Cancer
- Trial name
- ExPre 01 (NCT04923672)
- Testing
- Moderate continuous exercise, High intensity interval exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Breast Cancer
Computed Optical Margin Assessment for Breast Cancer Surgery, Phase I (Part A)
This multi-center, prospective, open label study analyzed specimens from fifty subjects at two study sites. Patients scheduled to undergo breast-conserving surgery were recruited in accordance with the inclusion and exclusion…
- Trial name
- NCT01699867
- Testing
- Optical coherence tomography
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Diagnostic Photonics, Inc.
Parathyroid Gland Adenoma, Primary Hyperparathyroidism
Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary Hyperparathyroidism
This clinical trial studies the omission of intact parathyroid hormone testing during surgery in treating patients with primary hyperparathyroidism.
- Trial name
- NCT03011736
- Testing
- Laboratory Biomarker Analysis, Parathyroidectomy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Roswell Park Cancer Institute
Liver Cancer, Surgery
Navigated Laparoscopic Microwave Ablation of Tumor Mimics in Pig Liver - an Ex-vivo Trial
In primary and secondary liver tumors microwave ablation could be an alternative to surgical resection.It could be performed laparoscopically.
- Conditions
- Liver Cancer, Surgery, Navigation, Spatial
- Trial name
- NCT04106453
- Testing
- navigated microwave ablation, ultrasound guided navigation
- Where
- Germany
- Volunteers
- 4 people
- Sponsor
- Universitätsklinikum Köln
Pain Score, Morphine Consumption
Comparison of Efficacy of Regional Blocks in Breast Surgeries.
After Standardized anesthetic induction patients were randomly given regional blocks. Group A recieved erecter spinae plane block \& group B recieved combined serratous anterior and pecto-intercoatal facial plane block.
- Trial name
- NCT07362472
- Testing
- Regional nerve blocks
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Cachexia, Oesophageal Cancer
REVOLUTION Surgery (REVOLUTION Surgery)
Some people with cancer suffer from muscle wasting, lose weight and feel tired. This process, termed cachexia, is a significant problem and can lead to a reduction in both quality and quantity of life.
- Conditions
- Cachexia, Oesophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT05642819
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Edinburgh
Breast Surgery
ER-One: A Double-blind Trial of Erector Spinae Block (ESP) Versus Paravertebral Block (PVB) Before Breast Cancer Surgery
The block (ESP or PVB) will be performed preoperatively in the recovery room under standard monitoring. After setting a peripheral venous access, patient will be installed on lateral decubitus position on the opposite side of the…
- Trial name
- ER-One (NCT04827030)
- Testing
- Ropivacaïne Hydrochloride by Erector Spinae block, Ropivacaïne Hydrochloride by Paravertebral block
- Where
- 5 sites in France
- Volunteers
- 292 people
- Sponsor
- Institut Curie
Stage III Fallopian Tube Cancer AJCC v7, Stage III Ovarian Cancer AJCC v6 and v7
Epacadostat Before Surgery in Treating Patients With Newly Diagnosed Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
This pilot Early Phase I clinical trial studies epacadostat before surgery in treating patients with newly diagnosed stage III-IV epithelial ovarian, fallopian tube, or primary peritoneal cancer.
- Conditions
- Stage III Fallopian Tube Cancer AJCC v7, Stage III Ovarian Cancer AJCC v6 and v7, Stage III Primary Peritoneal Cancer AJCC v7, Stage IIIA Fallopian Tube Cancer AJCC v7
- Trial name
- NCT02042430
- Testing
- Epacadostat, Laboratory Biomarker Analysis, Therapeutic Conventional Surgery
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- National Cancer Institute (NCI)
Esophageal Cancer
Genes in Predicting Outcome in Patients With Esophageal Cancer Treated With Cisplatin, Radiation Therapy, and Surgery
RATIONALE: Studying samples of tissue in the laboratory from patients with cancer may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00898495
- Testing
- loss of heterozygosity analysis, polymerase chain reaction, polymorphism analysis
- Volunteers
- 118 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Mesothelioma, Solitary Fibrous Tumor of the Pleura
Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma
The purpose of this study is to determine the response rate and overall survival in patients that have been diagnosed with mesothelioma and will undergo chemotherapy, surgery and intensity modified radiation therapy (IMRT) as…
- Trial name
- NCT02613312
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mayo Clinic
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