Clinical trials: Surgical Outcome
Prostate Cancer, Bladder Cancer
USPIO-enhanced and Diffusion-weighted MRI for the Detection of Pelvic Lymph Node Metastases
Preoperative detection of lymph node metastases in patients with prostate or bladder cancer is crucial for selection of the appropriate treatment strategy (surgery, androgen deprivation with/or without radiation therapy or…
- Trial name
- NCT00622973
- Testing
- Imaging: diffusion-weighted MRI, Sinerem (USPIO) enhanced MRI
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain
Comparison of Ultrasound and Nerve Stimulation Technique for Continuous Sciatic Nerve Block
The most useful method to manage pain after major foot and ankle surgery is infusion of local anesthetic with a catheter close to the sciatic nerve in the popliteal space above the knee joint.
- Trial name
- NCT00497276
- Testing
- placement of popliteal catheter
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Metastatic Spine Tumor
Metastatic Tumor Research and Outcomes Network
The registry aims to collect patient information such as patient demographics, co-morbidities, clinical, diagnostic, and therapeutic data, as well as information on adverse events and HRQOL outcomes specific for patients with…
- Trial name
- MTRON (NCT02830451)
- Where
- 24 sites in United States, Australia and 8 more
- Volunteers
- 2,417 people
- Sponsor
- AO Innovation Translation Center
Ptosis, Eyelid
Efficacy of Aurosling in Frontalis Sling Suspension Surgery
To Study the Efficacy of Aurosling as a suspension material in Frontalis suspension surgery in ptosis
- Trial name
- NCT00753831
- Testing
- Aurosling
- Where
- India
- Volunteers
- 16 people
- Sponsor
- Aurolab
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
Cognitive Behavioral Therapy (CBT) After Lumbar Spinal Fusion in Patients With High Pain Catastrophizing
Catastrophizing has emerged as the strongest independent predictor for persistent postsurgical pain. Although behavioral interventions, including Cognitive Behavioral Therapy (CBT), have been shown to reduce the impact of…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Instability, Spinal Disease
- Trial name
- TRIBECA (NCT03969602)
- Testing
- Cognitive-behavioral Therapy, Biomedical and surgery-specific education
- Where
- Switzerland
- Volunteers
- 126 people
- Sponsor
- Neurocenter of Southern Switzerland
Immunonutrition, Surgical Outcome
Perioperative Supplementation With Immunonutrition and Its Impact on Surgical Outcome and Pain in Oral Cavity or Mandibular Tumours
The aim of this study was to investigate the effect of adding omega 3 and dipeptiven to standard feeding in head and neck patients who will undergo oral cavity tumour resection or mandibular tumour resection (immunonutrrition…
- Conditions
- Immunonutrition, Surgical Outcome, Pain, Oral Cavity
- Trial name
- NCT06339372
- Testing
- Standard feeding, Omega 3 and dipeptiven
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Cairo University
Hypertrophic Scar
A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic Scars
The purpose of this study is to determine the effectiveness of RXI-109 in reducing the recurrence of hypertrophic scar formation following elective revision of a pre-existing hypertrophic scar.
- Trial name
- NCT02246465
- Testing
- RXI-109
- Where
- 6 sites in United States, Honduras
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- RXi Pharmaceuticals, Corp.
To Determine Whether ERAS Can Reduce Length of Stay in Pregnant Women After Cesarean Section
Compare Outcome of Enhanced Recovery After Cesarean Surgery and Conventional Care
Research objective to compare outcome(Length of stay, pain score, opioid drug use, Bowel function and complication ) of ERAS protocol and conventional care in pregnant women after elective cesarean section in Rajavithi hospital.
- Trial name
- NCT04530851
- Testing
- ERAS
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Surgical Procedures, Operative
Determining Universal Processes Related to Best Outcome in Emergency Gastrointestinal Surgery: an International Evaluation
A multicentre, international evaluation of emergency abdominal surgery to establish surgical outcomes and identify common, modifiable best practice processes.
- Trial name
- GlobalSurg-1 (NCT02179112)
- Testing
- Emergency Abdominal Surgery
- Where
- United Kingdom
- Volunteers
- 10,745 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Coronary Disease
Reduced Manipulation of the Aorta and Neurobehavioral Outcome Trial
The purpose of this trial is to determine whether aortic manipulation in patients undergoing coronary bypass graft surgery leads to increased incidence of microemboli and subsequent impairment of neurobehavioral function.
- Trial name
- NCT00059319
- Testing
- single aorta clamp with retrograde cardioplegia, multiple aorta clamps with antegrade cardioplegia
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Selective Nerve Root Block, Selective Discectomy
Selective Nerve Root Block With Ultrasound Guidance Improves Surgical Outcome of Selective Discectomy in Patients With Multilevel Cervical Disc Disease
Disc degeneration is a natural part of growing older. Up to 60% of asymptomatic people have MRI findings that are positive. As a result, MRI only provides morphological information and may not be able to determine the clinical…
- Trial name
- NCT05145530
- Testing
- selective anterior cervical discectomy and fusion (ACDF), SNRB+ selective anterior cervical discectomy and fusion (ACDF)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Renal Cancer
Laparoscopic Versus Hand Assisted Laparoscopic Trans-peritoneal Laparoscopic Nephrectomy as One Day Surgery (i.e.: Are There Differences in Postoperative Outcome / Convalescence)
The purpose of this study is to describe the postoperative outcomes after laparoscopic transperitoneal nephrectomy and compare them with hand assisted laparoscopic nephrectomy with a focus on the limiting factors that prevent an…
- Trial name
- NCT02295982
- Testing
- Hand assisted laparoscopic nephrectomy
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Zealand University Hospital
Snoring
Pretreatment Assessment of Oropharynx Ans Soft Palate Radiofrequency Surgery - a Multi-center Study
Interstitial radiofrequency (RF) surgery of the soft palate (SP) is an established option in the treatment of habitual snoring. The decision making process in the management of habitual snoring would benefit from diagnostic…
- Trial name
- NCT01223859
- Testing
- Interstitial soft palate surgery
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Scoliosis
Anesthesiologic Management Effect on Perioperative Outcome in Scoliosis Surgery
Alteration of evoked potentials is described in cases with using inhalation anaesthetics. Muscle relaxants are contraindicated in case of motor evoked potentials except for initial dose for intubation of the patient.
- Trial name
- SCOL (NCT04423146)
- Testing
- The evocation of reproducible motor evoked potential according to the different BIS levels
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Brno University Hospital
Cardiac Surgical Procedures
Impact of Cerebral Monitoring on Neurologic Outcome in Cardiac Surgery
Neurologic complications after cardiac surgery range over a wide spectrum including postoperative delirium (PD), postoperative cognitive dysfunction (POCD) and cerebrovascular accidents (CVA).
- Trial name
- NCT02006212
- Testing
- If any intraoperative EEG abnormality and/or asymmetry is detected a cerebral CT scan will be performed in the immediate postoperative period
- Where
- Belgium
- Volunteers
- 1,500 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Anesthesia, Analgesia
Patient Reported Outcome After Bariatric Surgery
Prospective association study to analyse patients' outcome after bariatric surgery. Outcome comprises postoperative pain, analgesia, postoperative side-effects, long-lasting pain, patients' impairment in daily living.
- Conditions
- Anesthesia, Analgesia, Bariatric Surgery
- Trial name
- NCT03490630
- Where
- Switzerland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Disease, Myocardial Infarction
Outcome After Coronary Artery Bypass Grafting
The E-CABG registry is a multicenter, European registry collecting data on the preoperative characteristics, treatment strategies and outcome of patients undergoing isolated coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Angina Pectoris
- Trial name
- E-CABG (NCT02319083)
- Testing
- Coronary artery bypass surgery
- Where
- Finland
- Volunteers
- 4,000 people
- Sponsor
- University of Oulu
Patients With Heart Failure Undergoing Cardiac Surgery
Telemedically Assisted Optimization for Heart Failure Patients Before Cardiac Surgery to Improve Perioperative Outcome
Patients with heart failure undergoing cardiac surgery face a significantly increased perioperative risk, yet no standardized strategy exists to mitigate this risk effectively.
- Trial name
- PREPARE-HF (NCT07391683)
- Testing
- PREPARE-HF disease management program, which includes:
- Where
- Austria
- Volunteers
- 162 people
- Sponsor
- Medical University Innsbruck
Proximal Femoral Fracture
Proximal Femoral Fractures - Patient Population, Risk Factors, Surgical Performance and Outcome
Proximal femoral fractures are a typical pathology in elderly patients after a low-energy trauma. This study analyses preexisting risk factors for proximal femoral fractures as well as for failing to reach the previous functional…
- Trial name
- ProFi (NCT03768622)
- Testing
- surgery for pertrochanteric femoral fracture, surgery for femoral neck fracture
- Where
- Switzerland
- Volunteers
- 2,906 people
- Sponsor
- University Hospital, Basel, Switzerland