Clinical trials: Surgical Performance
Aphakia, Corneal Astigmatism
Evaluation of the Safety and Performance of the HARMONI® Toric Lens
The purpose of this study was to evaluate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic (HMTIOL) in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Aphakia, Corneal Astigmatism, Cataract
- Trial name
- NCT03050697
- Testing
- HARMONI® Modular Toric Intraocular Lens, Cataract extraction with intraocular lens (IOL) implantation
- Where
- New Zealand
- Volunteers
- 16 people
- Sponsor
- ClarVista Medical
Emergency High-risk Abdominal Surgery
Functional Performance Following Emergency High-risk Abdominal Surgery
Emergency abdominal surgery is associated with high mortality rates, multiple postoperative complications and prolonged duration of hospital admission.
- Trial name
- NCT02124356
- Testing
- Evaluation of functional performance
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Periodontitis
Performance of the Treatment of Periodontitis According to the Bioperio® Protocol
This multicenter, prospective, single-arm observational study evaluated the clinical performance of the Bioperio® protocol, a standardized, patient-centered framework for managing periodontitis.
- Trial name
- BIOPERIO (NCT07507474)
- Testing
- Periodontal non surgical treatment, Oral Hygiene Instructions, Surgical Periodontal Treatment
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- University of Pisa
Hip Prosthesis Infection
Contribution of a Clinical Pathway for the Treatment of Hip Prosthesis Infections
The main objective is to determine the contribution of a clinical pathway to improve the effectiveness of medico-surgical management of hip prosthesis infections in terms of clinical cure.
- Trial name
- OSCAR-PH (NCT02660268)
- Testing
- Clinical Pathway
- Where
- 7 sites in France
- Volunteers
- 164 people
- Sponsor
- University Hospital, Grenoble
Nasal Obstruction, Septoplasty Surgeries
Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume
This retrospective study aims to evaluate the effect of surgical correction of nasal obstruction on aerobic performance parameters in male athletes aged 20-32 years.
- Conditions
- Nasal Obstruction, Septoplasty Surgeries, Athletic Performance
- Trial name
- NCT06957262
- Testing
- Surgical correction of nasal obstruction
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Tuba Melekoğlu
Hearing Loss
Ponto Implantation Using a Minimally Invasive Surgical Technique
This multi-centre study funded by Oticon Medical AB will be conducted at seven hospitals across Europe (UK, Sweden, Denmark and the Netherlands).
- Trial name
- NCT04606823
- Testing
- Minimally invasive surgery, Glasgow Benefit Inventory (GBI), Additional follow-up visits after surgery
- Where
- 7 sites in Denmark, Netherlands and 2 more
- Volunteers
- 52 people
- Sponsor
- Oticon Medical
Rectal Cancer, Recurrent Rectal Cancer
SGM-101 in Locally Advanced and Recurrent Rectal Cancer
Near-infrared fluorescence-guided oncologic surgery (EGOS) with the use of a tumor specific tracer (SGM-101) developed by Surgimab can provide valuable intra-operative information about tumor location and extensiveness, which can…
- Trial name
- SGM-LARRC (NCT04642924)
- Testing
- SGM-101
- Where
- 4 sites in Netherlands
- Volunteers
- 203 people
- Sponsor
- Leiden University Medical Center
Body Temperature Changes
Cooling Vest May Reduce Heat Stress During Surgery
The investigators will propose a randomized cross-over trial using a uniform and strongly balanced 4-period design in which will include four operations for each surgeon.
- Trial name
- NCT04511208
- Testing
- Cooling Vest, Without cooling vest
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Cataract
CAtaract ASSessment of IntrOcular Lens Objective PErformancE
Prospective, interventional, non-invasive, monocentric, longitudinal, non-randomized study
- Trial name
- CASSIOPEE (NCT06168617)
- Testing
- Performance tasks in daily life
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Prostate Cancer Surgery, Head and Neck Cancers
Investigating the Diagnostic Performance of High-resolution Specimen PET-CT in Determining Margin Status in Cancer Resection
Surgical removal is the treatment for many different cancers. Patient outcomes depend on complete cancer removal with no tumour present at the edge of the section removed (specimen).
- Trial name
- eXcision (NCT06676943)
- Testing
- XEOS AURA 10 specimen PET-CT scan of tumour specimens
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Thrombus, Embolus
A PMCF Study Confirm the Performance and Safety of the TufTex Over-the-Wire (OTW) Embolectomy Catheters
A PMCF study to confirm the performance and safety of the LeMaitre® TufTex Over-the-Wire Embolectomy Catheter
- Conditions
- Thrombus, Embolus, Occlusion; Vessel
- Trial name
- OTW (NCT05386342)
- Testing
- TufTex Over-the-Wire Embolectomy Catheter
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 112 people
- Sponsor
- LeMaitre Vascular
Breast Implant Revision, Congenital Breast Defect Correction
Scaffold-guided Breast Surgery
The clinical trial is testing the use of a novel method to grow new tissue within the breast injecting fat tissue harvested from patient's own fat deposits.
- Trial name
- NCT05437757
- Testing
- Surgical implantation of the PCL Breast scaffold with autologous fat grafting
- Where
- Australia
- Volunteers
- 19 people
- Sponsor
- BellaSeno Pty Ltd
Sepsis, SIRS
The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRS
A non-interventional, prospective observational study to assess the performance of SeptiCyte® Lab to diagnose patients identified as suspected of sepsis in general medical and surgical wards with infection-positive from…
- Trial name
- NCT02704871
- Testing
- SeptiCyte Lab molecular diagnostic test (non-interventional)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Immunexpress
Anesthesia, Pain Management
NoL Monitor Performances of Nociceptive and Non-nociceptive Stimuli Discrimination During Robotic Surgery
Anesthesia quality and safety have improved over the past decades, thanks to improved monitoring devices. No nociception monitoring is currently part of the standard of care.
- Trial name
- ROBOTNOL (NCT04566536)
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prehabilitation, Malnutrition
Prehabilitation for Colorectal Cancer Patients With Low Functional Capacity and Malnutrition
Despite multi-modal prehabilitation (nutrition, exercise, and psychosocial interventions), 60% of older elective colorectal cancer surgery patients with poor physical function were unable to reach a minimum preoperative 400m…
- Conditions
- Prehabilitation, Malnutrition, Physical Functional Performance
- Trial name
- NCT05999370
- Testing
- Nutrition, Exercise
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University
Intravenous Drug Usage
Impact of Priming the Infusion System on the Performance of Target-controlled Infusion of Remifentanil
The investigators attempted to determine an adequate priming volume for our infusion system, and investigated the extent of a possible delay of the drug effect, that would result from mechanical defects of the infusion system…
- Trial name
- NCT01477905
- Testing
- Remi50 with prime, Remi20 with prime
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Ajou University School of Medicine
Functional Capacity, Fatigue
Cycle-ergometer in the Postoperative of Thoracic Surgery
Post-lateral thoracotomies and assisted thoracic surgery (CTVA) are the main surgical approaches for pulmonary resections. One of the counterpoints of these surgical approaches is postoperative pain, which in addition to causing…
- Conditions
- Functional Capacity, Fatigue, Dyspnea, Muscle Strength
- Trial name
- CE_PTS (NCT03229070)
- Testing
- Interval effort group, Continuous effort group
- Volunteers
- 135 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Heparin-induced Thrombocytopenia (HIT)
Rapid Diagnosis of Heparin-Induced Thrombocytopenia in Surgical Critically Ill Patients
The early diagnosis of heparin-induced thrombocytopenia is particularly difficult in surgical critically ill patients. If the use of rapid immunological diagnostic methods and pretest scoring systems has been proposed in the…
- Trial name
- TIH (NCT02790567)
- Testing
- HEP score, 4Ts score, ID-PaGIA test
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Health Behavior
Self-Reported Surgeon Health Behaviours: A Multicentre, Observational Exploration With the Association of Surgeons in Training Into the Modifiable Factors That Impact Surgical Performance
Introduction: Surgeons regularly educate patients on health promoting behaviours including diet, sleep and exercise. No study thus far has explored surgeons' personal compliance with these health-behaviours and their relationship…
- Trial name
- NCT04677036
- Testing
- No intervention is given
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Diabetic Ulcers, Venous Leg Ulcer
PMCF Study of Debridement Pad
The design of the study is a clinical trial of Debridement Pad in subjects with superficial, chronic and acute wounds consisting of Diabetic ulcers, Arterial and Venous Leg ulcers, Pressure ulcers, Postoperative wounds healing by…
- Conditions
- Diabetic Ulcers, Venous Leg Ulcer, Arterial Leg Ulcer, Pressure Ulcer
- Trial name
- NCT07255937
- Testing
- Debridement Pad
- Where
- Spain
- Volunteers
- 184 people
- Sponsor
- Advanced Medical Solutions Ltd.