Clinical trials: Surgical Planning
Non-Small Cell Lung Cancer (NSCLC)
A Study of Nivolumab and Ipilimumab in Untreated Participants With Stage 3 Non-small Cell Lung Cancer (NSCLC) That is Unable or Not Planned to be Removed by Surgery
The primary purpose of the study is to compare the effectiveness of nivolumab plus concurrent chemoradiotherapy (CCRT) followed by nivolumab plus ipilimumab vs CCRT followed by durvalumab in participants with untreated Locally…
- Trial name
- CheckMate73L (NCT04026412)
- Testing
- nivolumab, ipilimumab, durvalumab
- Where
- 183 sites in United States, Argentina and 25 more
- Volunteers
- 925 people
- Sponsor
- Bristol-Myers Squibb
Surgical Education
Patient Specific Virtual Reality for Simulation of Spine Procedures: an Intelligent Image Segmentation, Registration and 3-dimensional Visualization in a Unified Virtual Reality Workflow for Image Guided Therapy, and Education - Physician Testing
The goal of this clinical trial is to learn if patient specific virtual reality (VR) simulations can be used for surgical orthopaedic education in resident and fellow physician populations.
- Trial name
- NCT06714539
- Testing
- Patient Specific Virtual Reality Stimulation
- Volunteers
- 13 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pengblock, over65years
Comparıson Of The Effects Of Perıcapsulary Nerve Group Block (Peng Block) And Lumbar Erector Spına Plan Block (Lesp Block) On Postoperatıve Opıoıd Consumptıon
The aim is to demonstrate that lumbar ESP block provides more effective postoperative analgesia than PENG block in geriatric patients with hip fractures, and reduces postoperative opioid consumption more than PENG block
- Conditions
- Pengblock, over65years, Lumbar Erector Spinae Plane Block, Hipfracture
- Trial name
- NCT06995079
- Testing
- Postoperative pain assessment of patients who underwent block
- Volunteers
- 70 people
- Sponsor
- Sakarya University
Chronic Periodontitis, Clinical and Microbiological Effects
Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis.
Background: Peridontitis is a group of diseases with complex bacterial etiology that affects a large proportion of the Chilean and worldwide population.
- Trial name
- Metro + Amoxi (NCT01211223)
- Testing
- Administration of Metronidazole plus Amoxicillin
- Where
- Chile
- Volunteers
- 42 people
- Sponsor
- University of Chile
Breast Cancer Female
Prone Breast Radiotherapy Treatment Planning Observational Study
The study purpose is to evaluate whether or not clinical characteristics of women with breast cancer can predict which position for radiation treatment, prone or supine, will be associated with a dosimetry gain.
- Trial name
- HUGProne (NCT02237469)
- Testing
- Prone and supine simulation
- Where
- Switzerland
- Volunteers
- 280 people
- Sponsor
- Vincent Vinh-Hung
Lumbar Spinal Stenosis, Spondylolisthesis
Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
The objective of the clinical investigation is to assess the proportion of lumbar spinal stenosis surgical treatment plans that change when an objective measurement of spinal stability is included and applied following a simple…
- Trial name
- SPSI (NCT03754972)
- Testing
- Sagittal plane shear index (SPSI)
- Where
- 3 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Medical Metrics Diagnostics, Inc
Hepatopancreaticobiliary (HPB) Malignancy, Ovarian Cancer (OvCa)
Comprehensive Multimodal Prehabilitation Alone or With Neoadjuvant Therapy Before Major Cancer Surgery
In this 2-arm, non-randomized, phase II trial, the investigators will evaluate the efficacy and safety of comprehensive multimodal prehabilitation (CMMP) alone or in combination with planned neoadjuvant (NAT) in pre-frail/frail…
- Conditions
- Hepatopancreaticobiliary (HPB) Malignancy, Ovarian Cancer (OvCa), Kidney Cancers, Bladder Cancer
- Trial name
- NCT07050771
- Testing
- Comprehensive multimodal prehabilitation (CMMP)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- The Methodist Hospital Research Institute
This Study Evaluates the Effects of Different Fascial Plane Blocks on Intraoperative Anesthesia and Analgesic Consumption in Non-intubated VATS Procedures
Comparison of SPSIP Block and SAP Block in Non-Intubated Uniportal VATS.
Comparison of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block in Uniportal Video-Assisted Thoracoscopic Surgery Without Intubation Single-port video-assisted thoracoscopic surgery without…
- Trial name
- NCT07440199
- Testing
- Serratus Anterior Plane Block (SAPB) group, Serratus posterior superior intercostal plane block group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Firat University
Accuracy of Fully Guided Dental Implant Placement Based on Clinician Experience and Surgical Guide Support Type
Accuracy of Fully Guided Dental Implant Placement by Experienced and Novice Clinicians Using Different Surgical Guides
The goal of this clinical trial is to learn how accurate fully guided dental implant placement is when performed by experienced versus novice clinicians.
- Trial name
- NCT07112664
- Testing
- Fully Guided Dental Implant Placement Using Surgical Guide
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Abdelrahman Khalaf Eldabe
Evaluation of the Accuracy of Transferring the Virtual Planning to the Surgery
Accuracy of CAD/CAM Cutting Guides and Customized Titanium Plates for Virtual Planning Transfer in Bimaxillary Orthognathic Surgeries
In this research, we aim to use CAD/CAM surgical cutting guides for maxilla and mandible and customized titanium plates to guide all osteotomies and fixation of both arches.
- Trial name
- NCT04421144
- Testing
- orthognathic surgery
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Quadro-Iliac Plane Block, Erector Spina Plan Block
ESP Block Vs. QIPB for Lumbar Stabilization Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy and functional outcomes of the quadro-iliac plane block (QIPB) and the erector spinae plane block (ESPB) in patients undergoing lumbar…
- Conditions
- Quadro-Iliac Plane Block, Erector Spina Plan Block, Lumbar Stabilization Surgery, Pain Management
- Trial name
- NCT07789509
- Testing
- Quadro iliac Plane Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Mandibular Fractures, Maxillofacial Injuries
Virtual Surgical Planning and Preoperative Plate Bending for Maxillofacial Fractures
Purpose: Complex mandibular fractures are commonly associated with high-energy maxillofacial trauma and may result in disruption of mandibular continuity, facial deformity, malocclusion, and impaired mastication and speech.
- Conditions
- Mandibular Fractures, Maxillofacial Injuries, Fractures, Comminuted
- Trial name
- NCT07856589
- Testing
- Conventional Open Reduction and Internal Fixation With Intraoperative Plate Bending, Virtual Surgical Planning-Assisted Open Reduction and Internal Fixation With Preoperative Plate Bending
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Tibia Fractures, Trauma (Including Fractures)
Assessment of the Feasibility of Using a Preoperative Surgical Fracture Analysis Tool
This study aims to evaluate a preoperative fracture analysis tool that uses 3D visualization and biomechanical modeling to assist surgeons in planning screw and plate fixation for complex tibial plateau fractures.
- Conditions
- Tibia Fractures, Trauma (Including Fractures), Surgical Planning
- Trial name
- NCT07193524
- Testing
- 3D Fracture Analysis Tool
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Adult Spinal Deformity, Sagittal Deformity
A Novel Classification of Sagittal Spinal Alignment to Aid Surgical Planning for Adult Spinal Deformity
Surgical outcomes, including radiographic outcomes, patient-reported outcomes, postoperative complications, and revision surgery rates, were compared in patients with adult spinal deformity who underwent correction surgery with…
- Conditions
- Adult Spinal Deformity, Sagittal Deformity, Sagittal Alignment, Sagittal Imbalance
- Trial name
- CSSAASD (NCT06470152)
- Testing
- Correction strategy in reference to our PI-dependent clustering of sagittal alignment, Correction strategy in reference to the SAAS score
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Post Operative Pain
Continuous Versus Single-Shot Spinal Anesthesia for Orthopedic Surgery
A study was conducted to compare the effectiveness of continuous spinal anesthesia (CSA), single-shot spinal anesthesia (SSSA), and general anesthesia (GA) in patients over 60 years of age undergoing elective surgical repair of a…
- Trial name
- NCT06625606
- Testing
- Bupivacaine 0.5% Injectable Solution, Isoflurane Inhalant Product
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Benha University
Head and Neck Squamous Cell Carcinoma
A Study to Investigate Biomarker Effects of Pre-Surgical Treatment With DNA Damage Repair (DDR) Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC).
This biomarker study has been designed to assess the effects of different agents in both tumour tissue and peripheral samples to help inform the best combinations of DDR agents with immuno-oncology (IO) therapies.
- Trial name
- NCT03022409
- Testing
- Ceralasertib, Olaparib
- Where
- 4 sites in United States, France and 1 more
- Volunteers
- 21 people
- Sponsor
- AstraZeneca