Clinical trials: Surgical Procedure, Operative
Social Phobia, Periodontal Diseases
Nonsurgical Periodontal Treatment in Patients With Social Phobia
Objective: To investigate the impact of nonsurgical periodontal treatment in patients with social anxiety disorder (SAD) and controls without phobia.
- Trial name
- NSPTSP (NCT03241277)
- Testing
- Non surgical periodontal treatment
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Benign Prostatic Hyperplasia, Bladder Outlet Obstruction
Urinary CTGF in Benign Prostatic Obstruction
Benign prostatic obstruction (BPO) is one of the most common causes of bladder outlet obstruction (BOO) and may lead to progressive structural and functional alterations in the bladder over time.
- Conditions
- Benign Prostatic Hyperplasia, Bladder Outlet Obstruction, Lower Urinary Tract Symptom
- Trial name
- NCT07416981
- Volunteers
- 50 people
- Sponsor
- Tarik Emre Sener
Gastroesophageal Reflux
Laparoscopic Nissen Versus Anterior Partial Fundoplication
The most widely used operative technique for gastroesophageal reflux is total fundoplication where the gastric fundus is sutured around the distal esophagus like a wrap.
- Trial name
- NCT01669330
- Testing
- Nissen fundoplication, Laparoscopic antireflux surgery ad modum Watson
- Where
- 4 sites in Sweden
- Volunteers
- 72 people
- Sponsor
- Region Skane
Obesity, Asthma
The Effect of Obesity on Lung Functioning
This research study is looking at the effects of weight loss, due to surgery or structured weight-loss program on lung function, inflammation in your body and lungs, asthma and asthma symptoms.
- Trial name
- NCT00284895
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Jewish Health
Treatment of Terrible Triade Injury of the Elbow Joint
Evaluation of Surgical Treatment of Terrible Triade Injury of the Elbow Joint
) Terrible triad injury of the elbow is a complex injury that is classically defined as elbow dislocation along with fractures of the coronoid process of the ulna and the radial head.
- Trial name
- NCT04578977
- Testing
- Functional assessment of surgical treatment of terrible triade injury of the elbow
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Achilles Insertional Tendinopathy, Achilles Tendinopathy
Single-Row Versus Double-Row Repair for Achilles Insertional Tendinopathy
Achilles insertional tendinopathy may require surgical debridement and tendon reattachment when non-operative treatment fails. Single-row and double-row repairs are used, with biomechanical studies favoring double-row, but…
- Trial name
- STRIDE (NCT07323875)
- Testing
- Single-row repair of the Achilles tendon at its calcaneal insertion, Double-row repair of the Achilles tendon at its calcaneal insertion
- Where
- Canada
- Volunteers
- 166 people
- Sponsor
- Women's College Hospital
Cerebral Palsy
Effects of Walking Analysis on Surgical Outcomes
The purpose of this study is to evaluate the effects of pre-operative gait analysis testing on surgical outcomes in children with cerebral palsy who have problems walking.
- Trial name
- NCT00114075
- Testing
- Surgery with gait analysis report, Surgery without gait analysis report
- Where
- 2 sites in United States
- Volunteers
- 186 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
COVID
Impact of Pandemic COVID-19 on Surgical Specialities Residents in Italy
The Coronavirus Emergency has severely affected Italian Healthcare National System. This event made it necessary to adopt extraordinary containment measures and to allocate extraordinary resources in Italian hospitals.
- Trial name
- NCT04338945
- Testing
- COVID-surgRES questionaire
- Where
- 7 sites in Italy
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia
Anesthesia, Carbon Dioxide
EtCO2 Level to Control Intraoperative Bleeding and Improve the Quality of Surgical Field Vision in Septorhinoplasty
It is unknown whether different end-tidal carbon dioxide pressure levels have a clinically significant effect on bleeding and surgical field quality in septorhinoplasty, especially during controlled hypotension.
- Conditions
- Anesthesia, Carbon Dioxide, Surgical Blood Loss
- Trial name
- EtCO2 (NCT05497375)
- Testing
- The amount of intraoperative bleeding, Quality of the intraoperative surgical field, Surgeon Satisfaction
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bezmialem Vakif University
Papilla Reconstruction
Comparison of Connective Tissue Graft Versus Titanium Papillary Inserts in the Surgical Reconstruction of Interdental Papilla.
Aim and Objectives: The study aimed to evaluate the effectiveness of titanium inserts for interdental papilla reconstruction, comparing it with the Han and Takei technique using subepithelial connective tissue grafts.
- Trial name
- NCT07401667
- Testing
- TITANIUM INSERTS, CONNECTIVE TISSUE GRAFT
- Where
- India
- Volunteers
- 18 people
- Sponsor
- Dr R Viswa Chandra
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time
The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I…
- Conditions
- Malocclusion, Angle Class II, Malocclusion, Angle Class III, Dentofacial Deformities, Osteotomy, Le Fort I
- Trial name
- TiPlateRCT (NCT07841067)
- Testing
- 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Future University in Egypt
Sarcoma, Bone Tumor
Cost-effectiveness Evaluation of the Use of a Patient Specific Instrument for Surgical Resection of Malignant Bone Tumor Within the Pelvis Versus the Conventional Surgical Treatment
Primitive malignant bone tumor or mixt tumor (compounded of soft tissues and bone) is a rare pathology particularly within the pelvis, the sacrum or the hip (between 25 and 80 new cases in France per year).
- Trial name
- MARGIC (NCT02544711)
- Testing
- Patient specific instrument, Conventional surgical treatment
- Where
- 8 sites in France
- Volunteers
- 88 people
- Sponsor
- Nantes University Hospital
Blood Loss, Postoperative, Blood Loss, Surgical
EFFECT OF TRANEXAMIC ACID ON PERIOPERATIVE BLOOD LOSS IN REAMED INTRAMEDULLARY NAILING OF DIAPHYSEAL FEMORAL AND TIBIAL FRACTURES: A PROSPECTIVE COMPARATIVE STUDY
Perioperative blood loss is one of the most frequently encountered and significant complications of spine surgery. Intraoperative and post-operative bleeding cause various complications and negatively affect patient outcomes.
- Conditions
- Blood Loss, Postoperative, Blood Loss, Surgical, Femoral Fracture, Tibial Fracture
- Trial name
- NCT07625709
- Testing
- Intervention with Tranexamic Acid, Control group (Normal Saline)
- Where
- Nepal
- Volunteers
- 54 people
- Sponsor
- Kathmandu University School of Medical Sciences
Abdominal Aortic Aneurism, Abdominal Aortic Rupture
Haemostasis Management of Abdominal Aortic Procedures
Comparative study on efficacy of haemostatic therapy guided either by standard laboratory coagulation parameters or point-of-care testing in patients undergoing vascular surgical procedures.
- Conditions
- Abdominal Aortic Aneurism, Abdominal Aortic Rupture, Perioperative/Postoperative Complications, Surgical Blood Loss
- Trial name
- NCT03426839
- Testing
- Coagulation tests
- Volunteers
- 40 people
- Sponsor
- University of Pecs
Periodontal Diseases, Pregnancy Gingivitis
Stress and Gingival Inflammation in Non-pregnant and Pregnant Women
Background: The purpose of the present study is to research whether stress scale scores alter with relationship to gingival inflammation and examine the impact of non-surgical periodontal therapy during pregnancy on the levels of…
- Trial name
- NCT03336957
- Testing
- periodontal treatment
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Cirrhosis, Liver, Hepatocellular Carcinoma
CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection
In this project, the preoperative anatomical location of micro hepatocellular carcinoma under the guidance of CT can provide guidance for accurate surgical resection.
- Trial name
- CTMH (NCT05433467)
- Testing
- CT-guided localization for micro hepatocellular carcinoma before surgical resection
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Northern Jiangsu People's Hospital
Periodontal Diseases
The Effect of Periodontal Treatment on Psoriasis
There is a relationship between psoriasis and periodontal disease. This relationship may be double-sided.
- Trial name
- NCT03939936
- Testing
- Psoriatic measurements, Non-surgical periodontal treatment, saliva samples
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ozge Gokturk
Surgical Procedures, Operative
ETT Cuff Leak: TV Ratios
In the past 5 years cuffed endotracheal tubes (ETT) have become the standard of care in pediatrics. However, hyperinflation of the cuff can compromise the tracheal mucosal perfusion while an inadequate seal may impact ventilation…
- Trial name
- NCT02768831
- Testing
- CPAP, Tidal volume
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nationwide Children's Hospital
Chronic Postsurgical Pain, Chronic Post-surgical Pain
Prevention of Postsurgical Chronic Pain in Children and Adolescents (PREVENDOL)
Chronic postsurgical pain is a health problem with a great societal impact: approximately 20% of all children and adolescents undergoing surgery will develop chronic pain.
- Conditions
- Chronic Postsurgical Pain, Chronic Post-surgical Pain, Chronic Postoperative Pain, Chronic Post-operative Pain
- Trial name
- NCT06638437
- Testing
- Cognitive-behavioral therapy
- Where
- 3 sites in Spain
- Volunteers
- 125 people
- Sponsor
- University Rovira i Virgili
Appendicitis
Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children
Several prior studies have demonstrated that medical management of acute appendicitis in adults is a safe first-line therapy option.
- Trial name
- NCT02991937
- Testing
- Piperacillin/Tazobactam, Surgical Treatment
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health