Clinical trials: Surgical Procedure, Operative
Glioma
ExAblate Blood Brain Barrier Disruption (BBBD) for Planned Surgery in Suspected Infiltrating Glioma
This study is designed to assess the safety and feasibility of using the ExAblate, Type 2 to temporarily disrupt the blood brain barrier in non-enhancing suspected infiltrating glioma.
- Trial name
- NCT03322813
- Testing
- ExAblate 4000 - Type 2
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- InSightec
Vaginal Fistula, Vesico Vaginal Fistula
Feasibility of the Menstrual Cup for VVF
This study examines the feasibility and acceptability of the vaginal menstrual cup for short-term management of vesicovaginal fistula (VVF) among 11 women seeking treatment at a health facility in Ghana.
- Conditions
- Vaginal Fistula, Vesico Vaginal Fistula, Obstetric; Injury
- Trial name
- FMCVVF (NCT03414060)
- Testing
- Menstrual Cup
- Where
- Ghana
- Volunteers
- 11 people
- Sponsor
- University of Ghana Medical School
Surgical Procedure, Unspecified, Intensive Care Units (ICUs)
Continuous Connected Patient Care (CCPC), a Pilot Testing a Novel Device for Continuous Vitals Monitoring - Department of Anesthesia at PHC
To confirm feasibility and accessibility of the CCPC Platform (Oxymotion, Bridge Health Solutions medication adherence software, CloudDX home kit) in two different environments - in hospital and at-home, in patients undergoing…
- Trial name
- NCT06638073
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Medtronic - MITG
Endometriosis; Peritoneum
Is Laparoscopic Excision for Peritoneal Endometriosis Helpful or Harmful?
The trial seeks to test effect of laparoscopic excision of peritoneal endometriosis on pelvic pain. Data will also be gathered on quality of life and neuropathic pain.
- Trial name
- NCT05162794
- Testing
- Laparoscopy with excision, Laparoscopy without excision, Medical treatment-as-usual
- Where
- 5 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Pelvic Organ Prolapse, Surgical Procedure; Complications, Late Effect of Complications
LOOP VS DOUBLE SUTURE TECHNIQUES IN SACROSPINOUS FIXATION: A TWO-YEAR STUDY
This retrospective cohort study aimed to compare clinical outcomes between the classical double suture technique and a modified loop suture technique used in sacrospinous ligament fixation for stage 3 or 4 pelvic organ prolapse.
- Trial name
- NCT07106866
- Testing
- sacrospinous ligament fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Glaucoma, Blindness, Acquired
Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma.
Purpose: To assess the feasibility of a surgical technique and present the preliminary safety results of a new glaucoma device devoid of a tube in painful blind eyes.
- Conditions
- Glaucoma, Blindness, Acquired, End-Stage Glaucoma, Glaucoma Traumatic
- Trial name
- NCT03166566
- Testing
- Laminar drainage implant surgery.
- Volunteers
- 15 people
- Sponsor
- Federal University of Minas Gerais
Complication of Surgical Procedure
Synechie Afrer Rhinosug. Proc. 2024
Analyze the factors influencing the development of intranasal adhesions (synechiae), with particular emphasis on the use of nasal septal separators, and to suggest a solution to reduce this complication in the future.
- Trial name
- NCT06482866
- Testing
- Cottle's septoplasty and radiocoagulation conchoplasty
- Where
- Poland
- Volunteers
- 243 people
- Sponsor
- Mateusz Jan Stępiński
Periodontitis, Periodontal Diseases
Vitamin D Supplementation Prior to Non-surgical Periodontal Therapy
The purpose of this study is to test the feasibility i. e. to examine all aspects necessary for the implementation of a future randomized clinical trial (RCT) that aims to determine whether non-surgical periodontal treatment can…
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Inflammation, Inflammation
- Trial name
- NCT05398770
- Testing
- Vitamin D supplementation (30 µg/d)
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- University of Tromso
Primary Spondylodiscitis, Pyogenic Spondylodiscitis
One Year Results of Managing Primary Spondylodiscitis
Primary spondylodiscitis is a severe infectious condition involving the spinal discs and adjacent vertebrae. It often causes significant back pain and requires careful management, typically involving long-term antibiotics and…
- Conditions
- Primary Spondylodiscitis, Pyogenic Spondylodiscitis, Spinal Infection
- Trial name
- NCT07509983
- Volunteers
- 50 people
- Sponsor
- Assiut University
Chronic Post-surgical Pain
Pilot Study Evaluating Neuro-Imaging Correlates of Epigenetic Finding in Prediction of Chronic Postsurgical Pain
This pilot research study is being performed to learn more about pain and look at how pain changes brain chemistry and function. The research team would like to learn new information to better control chronic pain after surgery.
- Trial name
- NCT04681183
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Recurrent Glioblastoma
Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM
This is an open-label, phase 1b study to evaluate different approaches for CART-EGFR-IL13Ra2 dosing and further characterize the safety, feasibility, preliminary efficacy, and pharmacokinetics of CART-EGFR-IL13Ra2 cells in…
- Trial name
- NCT07209241
- Testing
- CART-EGFR-IL13Ra2 T cells
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Distal Radius Fracture
Surgical Field Quality Assessment and Complications in Distal Radius Fractures Using the Minimum Inflation Tourniquet Pressure.
Analyse surgical field bleeding, surgical time, and intraoperative pain in patients undergoing osteosynthesis of distal radius fractures using ischaemia pressure calculated based on Limb Occlusion Pressure, compared with Arterial…
- Trial name
- NCT07318194
- Testing
- PNEUMATIC TOURNIQUET INFLATION PRESSURE
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Consorci Sanitari de Terrassa
Coronary Artery Disease, Coronary Artery Disease (CAD)
Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)
This randomized multicenter trial compares coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI) in 358 patients with ischemic left ventricular dysfunction and multivessel coronary disease.
- Conditions
- Coronary Artery Disease, Coronary Artery Disease (CAD), Multivessel Coronary Artery Disease, CABG
- Trial name
- STICH 3*0-NL (NCT07269366)
- Testing
- CABG, PCI
- Where
- Netherlands
- Volunteers
- 358 people
- Sponsor
- University Medical Center Groningen
Oral Hemorrhage
Performance and Safety of the Surgical Hemostatic Agent "HEMOCOLLAGENE®" in Patients Requiring Oral Surgery
The aim of this study is to collect performance and safety data relating to the use and the follow-up of the HEMOCOLLAGENE® medical device in routine clinical practice from various hospitals and medical centers in oral dental…
- Trial name
- NCT05171231
- Testing
- HEMOCOLLAGENE® : Sterile absorbable hemostatic sponges based on bovine collagen - class III MD
- Where
- 10 sites in Belgium, France
- Volunteers
- 125 people
- Sponsor
- Septodont
Surgical Patients, Pulmonary Complication
Prophylactic Noninvasive Ventilation in vs Postoperative Standard Care in High Risk Patients According to ARISCAT Score
Postoperative pulmonary complications are one of the most common complications after surgery. Noninvasive ventilation has been proposed post-operatively to prevent postoperative pulmonary complications.
- Trial name
- ANTICIPUSC (NCT03629431)
- Testing
- Prophylactic non-invasive ventilation, postoperative standard care
- Where
- 3 sites in France
- Volunteers
- 266 people
- Sponsor
- Institut Cancerologie de l'Ouest
Post-surgical Inflammation
Tobradex BID Compared to TOBRADEX and TOBREX/Vehicle
The purpose of this study is to compare the new formulation of Tobradex to the current approved formulation
- Trial name
- NCT00404937
- Testing
- Tobradex (Antibiotic steroid combination)
- Sponsor
- Alcon Research
Epithelial Ovarian Cancer
Sentinel Lymph Node Mapping in Early-Stage Epithelial Ovarian Cancer Surgery
This prospective study aims to evaluate the feasibility and diagnostic performance of sentinel lymph node (SLN) mapping using indocyanine green (ICG) in patients undergoing surgery for early-stage epithelial ovarian cancer.
- Trial name
- NCT07593339
- Testing
- Sentinel Lymph Node Mapping, Indocyanine Green
- Volunteers
- 30 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Aortic Valve Stenosis
Validation of the "TASQ" in Patients Undergoing SAVR or TF-TAVI
Prospective, multi-centre, multi-national registry with a follow-up of 3 months, in five European countries and Canada (Toronto), with elective patients undergoing TF-TAVI (n=120) and isolated SAVR (n=120), respectively and a…
- Trial name
- TASQ (NCT03186339)
- Testing
- TAVI, SAVR, MM
- Where
- 10 sites in Austria, Canada and 5 more
- Volunteers
- 272 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Pilonidal Sinus, Pilonidal Disease of Natal Cleft
Asymmetric Primary Closure and Additional Skin Excision Technique.
The aim of this study was to reduce the residual dead-space volume with a modification following the standard Karydakis procedure.
- Conditions
- Pilonidal Sinus, Pilonidal Disease of Natal Cleft, Surgical Technique
- Trial name
- NCT03424057
- Testing
- Asymmetric Primary Closure and Additional Skin Excision Technique, Standard Karydakis technique.
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Siverek Devlet Hastanesi
Meningioma, Skull Base Meningioma
Cognitive Status After Removal of Skull Base Meningioma
The purpose of this prospectively enrolling trial is to assess long-term cognitive outcomes of patients undergoing surgery for resection of a meningioma associated with the frontal and temporal lobes.
- Conditions
- Meningioma, Skull Base Meningioma, Frontal Meningioma, Temporal Meningioma
- Trial name
- NCT04635657
- Testing
- Long-term Cognitive testing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ohio State University