Clinical trials: Surgical Procedure, open to volunteers
Stress, Stress and Burnout
Deep Relaxation Using Virtual Reality Intervention Before Surgery for Healthcare Professionals Working in the Operating Room
The goal of this clinical trials is to primary learn if deep relaxation using Virtual Reality (VR) compared to a low stimulus environment can lower perceived and measured stress in healthcare professionals working in the…
- Conditions
- Stress, Stress and Burnout, Stress Biomarkers
- Trial name
- DEEP_VR (NCT07470697)
- Testing
- Virtual Reality intervention, Low Stimulus Environment
- Where
- 2 sites in Denmark, Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Feasibility Studies
The Aim of This Study is to Assess the Feasibility of the Study Protocol and the Acceptability of the Mobile Application-Based Intervention. The Results Will Guide the Design and Evaluation of a Definitive, Larger-scale Study to Further Examine the Efficacy of the Refined Intervention.
This study is a pilot study for a larger future research project aimed at examining the effects of patient education delivered via a mobile application on patients' self-reported receipt of information in relation to their…
- Trial name
- NCT07589803
- Testing
- Digital patient education mobile application., Standard Care (in control arm)
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Peripheral Arterial Disease (PAD), Amputation
Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease
The goal of this clinical trial is to determine whether a personalised blood clot prevention plan is more effective than standard treatment in adults with peripheral artery disease (PAD) who have undergone a procedure to restore…
- Conditions
- Peripheral Arterial Disease (PAD), Amputation, Thrombosis, Thrombosis (Stent Thrombosis)
- Trial name
- NCT07613840
- Testing
- Aspirin, Clopidogrel, Ticagrelor
- Where
- 2 sites in United States
- Volunteers
- 484 people
- Sponsor
- Massachusetts General Hospital
Disc Herniations, Disc Herniation, Lumbar
Smartwatch Accuracy for Measuring Vitals and Anxiety Before Disc Surgery
This study aims to verify the accuracy of blood pressure, heart rate, blood oxygen saturation, anxiety level, and sleep cycle data measurements obtained from Samsung smartwatches compared to the currently accepted method used in…
- Conditions
- Disc Herniations, Disc Herniation, Lumbar, Cervical Disc Herniation, Preoperative Anxiety Score
- Trial name
- NCT07322523
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Halil Kalaycı
Ovarian Cancer
NeoAdjuvant ChemoTherapy With KELIM Guided Interval vs. Delayed Interval Debulking Surgery
A prospective, international, multi-center, interventional trial of advanced epithelial ovarian cancer patients offered three cycles of neoadjuvant chemotherapy (NACT) and triaged with KELIM score.
- Trial name
- NACT-KELIM ID (NCT07382479)
- Testing
- 3 cycles of NACT with unfavorable KELIM score will receive 3 more cycles of NACT followed by DIDS, 3 cycles of NACT with favorable KELIM score will undergo IDS followed by 3 cycles of NACT
- Volunteers
- 485 people
- Sponsor
- Aristotle University Of Thessaloniki
Bioprosthetic Valve Failure, Prosthetic Heart Valve Dysfunction
REVIVE-FR Registry
This registry aims to investigate treatment options for patients whose previously implanted biological aortic heart valve no longer functions properly.
- Conditions
- Bioprosthetic Valve Failure, Prosthetic Heart Valve Dysfunction, Structural Valve Deterioration, Prosthetic Heart Valve Thrombosis
- Trial name
- NCT07885761
- Testing
- TAVI-in-SAVR (Valve-in-Valve), THV-in-THV (Redo-TAVI), Surgical Explantation of a Failed Transcatheter Heart Valve
- Volunteers
- 200 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Compare Two Surgical Approaches Used in Total Hip Arthroplasty
Short-term Results of SuperPATH Versus Direct Lateral Approach In Primary Total Hip Arthroplasty: A Randomized Controlled Study.
Total hip arthroplasty (THA) has shown great success in relieving joint pain and disability and has been a procedure of choice for the treatment of end-stage degenerative joint diseases and trauma.
- Trial name
- NCT07633925
- Testing
- Surgical approaches: direct lateral approach for the hip and SuperPATH approach
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Head and Neck Squamous Cell Carcinoma
Neoadjuvant Toripalimab or Toripalimab in Combination With Carboplatin and Nab-paclitaxel in Untreated HNSCC (HNSCC-002)
This proposed study will evaluate the efficacy and safety of preoperative administration of Toripalimab or Toripalimab combined with nab-paclitaxel and carboplatin in Head and Neck Squamous Cell Carcinoma (HNSCC) who are about to…
- Trial name
- NCT04807140
- Testing
- Toripalimab, nab-paclitaxel, carboplatin, Toripalimab, Surgical resection
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cholelithiasis
Electrosurgical Patterns and Learning Curve in Elective Laparoscopic Cholecystectomy
This prospective observational study will examine how electrosurgical activation patterns during elective laparoscopic cholecystectomy are associated with surgeon experience and intraoperative difficulty.
- Trial name
- ELECTRO-LC (NCT07888491)
- Testing
- Elective laparoscopic cholecystectomy
- Where
- Croatia
- Volunteers
- 165 people
- Sponsor
- University Hospital of Split
Wound Heal
Vacuum Sealing Drainage (VSD) in Promoting Wound Healing and Reducing Complications in Post-Infected Obstetric and Gynecological Surgical Sites
This study aims to evaluate the efficacy of VSD in promoting wound healing and reducing complications, such as re-infection, prolonged hospitalization, and need for further surgical interventions, in obstetric and gynecological…
- Trial name
- NCT07525674
- Testing
- Conventional Wound Care Group, Vacuum Sealing Drainage (VSD) Group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Orthopedic Disorder
BoneFit: Multimodal Prehabilitation for People Preparing for Orthopaedic Surgery
To conduct a pilot feasibility study to determine the effect of a student-led prehabilitation service in people awaiting total hip or knee replacement surgery.
- Trial name
- BoneFit (NCT06341920)
- Testing
- Experimental: BoneFit intervention
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Hull
Diabetes Mellitus, Pancreas Transplantation
The Norwegian Pancreas Transplantation (PTx) Study
Several studies have shown acceptable results after Pancreas Transplantation (PTx) by substituting ATG with basiliximab, which is considered to convey a considerably lower number of adverse events.
- Conditions
- Diabetes Mellitus, Pancreas Transplantation, Allograft Rejection, Surgical Complication Nec
- Trial name
- PTx (NCT01957696)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Urinary Retention
Post Operative Urinary Retention (POUR) Following Thoracic Oncological Surgery
This is a feasibility study looking at whether the use of Tamsulosin could lower the high incidence of postoperative urinary retention (POUR) in older men who undergo an oncological thoracic surgical procedure for suspected or…
- Trial name
- NCT05657990
- Testing
- Tamsulosin
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Hackensack Meridian Health
Surgical Site Infection, Surgical Complication
A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™
Goal of the Clinical Trial: The purpose of this clinical trial is to learn whether Xperience™ surgical irrigation solution is more effective than a standard dilute povidone-iodine solution in reducing surgical site infections…
- Conditions
- Surgical Site Infection, Surgical Complication, Implant Infection, Implant Complication
- Trial name
- NCT06649890
- Testing
- Xperience™ Advanced Surgical Irrigation, Dilute Povidone-Iodine
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Degenerative Spine Disease, Spinal Stenosis Lumbar
VR-Cognitive Behavioral Therapy Prehabilitation for Spinal Deformity Surgery
The goal of this clinical trial is to learn whether a virtual reality-based cognitive behavioral therapy (VR-CBT) prehabilitation program can improve recovery and quality of life for adults undergoing elective spine surgery.
- Trial name
- VR-CBT (NCT07777679)
- Testing
- Virtual Reality-Based CBT Prehabilitation (VR-CBT), CBT Prehabilitation without Virtual Reality
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Irvine
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery
This randomized controlled trial evaluates whether a standardized perioperative neuroplastic intervention: the STEIN Protocol (Strategies and Techniques for Enhancing Integration and Neuroplasticity), consisting of pain…
- Trial name
- SLin (NCT07715591)
- Testing
- Music and Guided Imagery, Control, Music Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, Los Angeles
Metabolism and Nutrition Disorder
Amino Acid Metabolism in Fed Surgical Critically Ill Patients
Introduction Sarcopenia is defined as progressive generalized loss of skeletal muscle mass, strength and function. Sarcopenia due to lack of physical activity is a known phenomenon and is usually observed as a normal part of…
- Trial name
- NCT03451968
- Testing
- amino acid tracer injection for metabolism analysis
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Chronic Anal Fissure
Combined Method of Surgical Treatment of Anal Fissure
The purpose of this study is to improve treatment outcomes for patients with chronic anal fissure.
- Trial name
- NCT07268261
- Testing
- excision of the anal fissure with further relaxation of the internal sphincter with botulinum toxin A
- Where
- Russia
- Volunteers
- 122 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Anesthesia, Surgical Patients
Effect of Visual Aids Added to Informed Consent on Patient Understanding and Anesthesia Awareness
This prospective cluster-randomized controlled study aims to evaluate whether visual support material provided in addition to the standard written informed consent form improves patients' comprehension of informed consent and…
- Trial name
- NCT07461480
- Testing
- Standard Informed Consent, Visual Support Supplemented Informed Consent
- Volunteers
- 236 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Black Triangles Syndrome (BTS), Papilla Reconstruction
Clinical Evaluation of Different Treatments for Interdental Black Triangles
This randomized clinical trial aims to evaluate and compare the effectiveness of surgical and nonsurgical treatment approaches for the management of interdental black triangles.
- Trial name
- BT-RCT (NCT07548203)
- Testing
- Tube Grafting Technique for Papilla Reconstruction, Hyaluronic Acid (HA), Injection Molding Composite Technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
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