Clinical trials: Surgical Procedures, Elective
Intensive Care, Surgical
Postoperative Delirium in Adult Patients After Elective Craniotomy Under General Anaesthesia
Postoperative delirium may result in many adverse complications. At present little is known about postoperative delirium in patients after crniotomy because they may manifest similar symptoms to definitely delirium for some…
- Conditions
- Intensive Care, Surgical, Postoperative Care, Neurosurgery
- Trial name
- NCT03087838
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Capital Medical University
Intraoperative Bleeding
The Value of Tranxemic Acid to Reduce Intraoperative Blood Loss During Elective Cesarean Sections in High Risk Women
A full medical history will be obtained from all participants. Obstetric ultrasonography and laboratory tests will be performed.According to group assignment, either 1 g(10 mL) tranexamic acid stored in a dry container at 15…
- Trial name
- NCT03820206
- Testing
- Tranexamic Acid, Cesarean section
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Cesarean Section Wound
Interrupted Versus Continuous Subcuticular Skin Suturing in Elective Cesarean Section.
Non-diabetic pregnant women who undergo elective CS will be randomized into two groups: group I included women who has their skin closed with subcuticular interrupted mattress suture using non-absorbable polypropylene, and group…
- Trial name
- NCT03120806
- Testing
- Interrupted subcuticular skin closure, continuous subcuticular skin closure
- Where
- Egypt
- Volunteers
- 169 people
- Sponsor
- Cairo University
Intestinal Diseases, Intestinal Resection
Implementation of a Pediatric ERAS-based Protocol in Intestinal Resection With Primary Anastomosis
Enhanced Recovery After Surgery (ERAS) is a multimodal perioperative care strategy designed to reduce surgical stress, decrease postoperative complications, and accelerate recovery after surgery.
- Trial name
- PeERAS (NCT07504549)
- Testing
- Standardized Pediatric ERAS-Based Perioperative Protocol
- Where
- 9 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Michał Pasierbek
Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis
Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table
Appropriate fluid management is an important part of anesthesia in patients undergoing surgery, and several dynamic indices have been suggested to have high predictability for fluid responsiveness in patients receiving mechanical…
- Conditions
- Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis, Spinal Fractures, Scoliosis or Tumors
- Trial name
- NCT02826889
- Testing
- Philips Intelivue MP70 monitor, Pleth Variability Index (PVI)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Postpartum Hemorrhage, Tranexamic Acid
Tranexamic Acid in the Prevention of Postpartum Hemorrhage in Elective Caesarean Section
In obstetrics, postpartum haemorrhage (PPH) continues to be a major contributor to maternal morbidity and mortality worldwide. Uterine atony is the most common cause of PPH, and the prophylactic use of uterotonics, specifically…
- Trial name
- NCT04427618
- Testing
- Tranexamic acid, Normal saline
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Prostate Cancer
Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment
This study is being done to answer the following question: Is the strategy to give higher doses of radiotherapy treatment over a shorter period of time using special equipment and fewer treatments (also known as Stereotactic Body…
- Trial name
- ASCENDE-SBRT (NCT06235697)
- Testing
- Radiation, Radiation SBRT only, ADT
- Where
- 57 sites in United States, Canada
- Volunteers
- 710 people
- Sponsor
- Canadian Cancer Trials Group
Intubation, Intratracheal
Comparison of Miller's Blade and Airtraq Laryngoscope in Children
The Airtraq optical laryngoscope has recently been available in pediatric sizes. The investigators compared the efficacy of Airtraq with the Miller laryngoscope as intubation devices in paediatric patients.
- Trial name
- NCT02423317
- Testing
- Intubation with Miller's blade, Intubation with Airtraq
- Volunteers
- 60 people
- Sponsor
- Government Medical College, Haldwani
Hypotension
Predicting Hypotension Related to Spinal Anesthesia
This study aims to identify women at risk of low blood pressure (hypotension) after the usual cesarean anesthetic - a spinal anesthetic. Hypotension may be caused by dehydration.
- Trial name
- NCT01279889
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Coronary Arterial Disease (CAD), Peripheral Vascular Disease
Colonoscopy and Antiplatelet Therapy Trial
Patients on dual antiplatelet therapy )aspirin plus a P2Y12 inhibitor [clopidogrel, prasugrel, or ticagrelor]) undergoing screening or surveilance colonoscopy are at increased risk for bleeding from the procedure.
- Trial name
- CAPTT (NCT06613191)
- Testing
- Aspirin, P2Y12 inhibitor (clopidogrel, ticagrelor, prasugrel)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ochsner Health System
Hyperoxia, Hyperoxemia
Hyperoxemia and Oxygen Reserve Index During Neurointerventional Anesthesia
The goal of this observational study is to learn how often high blood oxygen levels (hyperoxemia) occur in adults receiving general anesthesia for planned (elective) neurointerventional procedures, such as brain aneurysm coiling…
- Conditions
- Hyperoxia, Hyperoxemia, Cerebrovascular Disorders, Intracranial Aneurysms
- Trial name
- NCT07859982
- Testing
- Oxygen Reserve Index Monitoring (Observational)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Remote Ischemic Preconditioning, Contrast Induced - Acute Kidney Injury
Remote Ischemic Preconditioning and Contrast Induced - Acute Kidney Injury in Patients Undergoing Elective PCI
Prospective, randomized, sham-controlled clinical study was conducted to assess whether RIPC reduces the incidence of CI-AKI measured standard way of using SCr concentration but also with the use of serum NGAL as a new potential…
- Trial name
- NCT03761368
- Testing
- Remote Ischemic Preconditioning
- Where
- Poland
- Volunteers
- 101 people
- Sponsor
- Medical University of Lodz
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture
Elective Treatment Rates and Surgical Non-eligibility Among Men and Women With Intact Abdominal Aortic Aneurysms
The overall aim is to determine the frequency by which women and men with intact abdominal aortic aneurysms (AAA) are treated with elective surgery at three vascular outpatient clinics in Europe, and to investigate whether the…
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Aneurysm, Aortic Aneurysm
- Trial name
- NCT05346289
- Testing
- Elective surgery for intact AAA
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Postoperative Pain
Elective Total Abdominal Hysterectomy With Preoperative Analgesia Intravenous Paracetamol Versus Placebo
The study aim to study to evaluate whether IV paracetamol reduces morphine use after TAH. Primary objective was to compare postoperative morphine consumption between the IV paracetamol and control groups.
- Trial name
- NCT07368790
- Testing
- Paracetamol
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Hemophilia A
Study Evaluating B-Domain Deleted Recombinant Factor VIII (BDDrFVIII, ReFacto AF) in Patients With Hemophilia A Undergoing Elective Major Surgery
This study will examine the efficacy and safety of ReFacto AF in patients with severe and moderately severe hemophilia A undergoing elective major surgery when administered by either bolus injections (BI) or continuous infusion…
- Trial name
- NCT00243659
- Testing
- ReFacto AF
- Where
- 17 sites in United States, Australia and 6 more
- Volunteers
- 30 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Periprocedural Myocardial Necrosis
Rosuvastatin in Preventing Myonecrosis in Elective Percutaneous Coronary Interventions (PCIs)
An increase in cardiac biomarkers has been shown to occur in 5% to 30% of patients after otherwise successful percutaneous coronary interventions (PCIs)(1) Apart from side-branch occlusion, intimal dissection and coronary spasm…
- Trial name
- ROMA (NCT01007279)
- Testing
- ROSUVASTATIN
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- University of Roma La Sapienza
Prevent Postopertive Nausea and Vomiting
Early Versus Delayed Oral Liquids and Soft Food After Elective Ceasarean Section
To compare the safety of early versus delayed oral feeding after uncomplicated cesarean section under spinal anesthesia
- Trial name
- NCT05233280
- Testing
- Oral liquids and soft food 2 hours postoperative
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Surgical Procedure
Postponement Rate of Elective Surgical Procedures
Postponement of elective surgical procedures is a major issue in health care facilities. It increases burden on hospitals and healthcare systems as well as misery of the patients and their family members.
- Trial name
- Postponement (NCT05352984)
- Where
- Pakistan
- Volunteers
- 1,221 people
- Sponsor
- Hayatabad Medical Complex
Peripheral Vein Cannulation Guided by Ultrasound
Ultrasound Guided Peripheral Venous Cannulation in Patient Undergoing Elective Surgery Under General Anesthesia.
This study evaluates two different techniques for peripheral venous cannulation in operating theatre. Ultrasound guided insertion of peripheral cannula in comparison with conventional approach without any ultrasound guidance.
- Trial name
- NCT05119985
- Testing
- Peripheral vein cannulation, Cannulation without ultrasound
- Where
- Czechia
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
In Vitro Fertilization
Corifollitropin Alfa Application in PCOS Patients
Corifollitropin alfa, single dose administered sustains multiple follicular development for 7 days. However, It may induce ovarian hyperstimulation syndrome (OHSS), especially in high responder women such as patients of…
- Trial name
- NCT02215135
- Testing
- Corifollitropin alfa
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
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