Clinical trials: Surgical Procedures, Elective
Bilateral Inguinal Hernia Repair, Open Upper Abdominal Surgeries
Ultrasound-guided Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Children Undergoing Elective Open Lower Abdominal Surgeries
To compare the postoperative analgesic efficacy of ultrasound-guided Quadratus Lumborum Block (anterior approach) versus Erector Spinae Plane Block (T10-T12 level), both performed bilaterally with 0.25% bupivacaine (0.5 mL/kg per…
- Trial name
- NCT07853586
- Testing
- ultrasound guided anterior oudratus lumborum block, Ultrasound guided erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Surgical Site Infection
Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
The aim of the study is to elucidate, if the colonization of bacteria is lower on the Novosyn® CHD suture compared to uncoated Polyglactin 910 suture, which will be assessed by the incidence of surgical site infections (SSI: A1…
- Trial name
- POLYNOVO-CHD (NCT05966961)
- Testing
- Novosyn® in emergency or elective laparotomy or laparoscopic surgery, Polyglactin 910 in emergency or elective laparotomy or laparoscopic surgery
- Where
- 4 sites in Italy, Spain
- Volunteers
- 2,998 people
- Sponsor
- Aesculap AG
Chronic Disease, Old Age; Debility
CONNECARE-Assuta-Case Study 2
The European Union's Horizon 2020 project issued a Call for Action [1] in December 2013 to design, develop, disseminate and evaluate new IT technologies for use in integrative treatment processes, with emphasis on complex adult…
- Trial name
- NCT03327246
- Testing
- Connecare self managment system
- Volunteers
- 220 people
- Sponsor
- Assuta Medical Center
Anesthesia, Endotracheal, Neonate
Cuffed Versus Uncuffed Tracheal Tubes in Neonates Undergoing Elective Surgery
This thesis aims to assess the safety and efficacy of usage of cuffed ETT in neonate undergoing elective surgeries.
- Trial name
- NCT05296668
- Testing
- Cuffed ETT (Microcuff®, Halyard Health Inc., Atlanta, GA, USA), Uncuffed ETT group
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kasr El Aini Hospital
Airway Management
VieScope Versus Direct Laryngoscopic Intubation
Patients requiring endotracheal intubation for elective surgery without expected difficult airway are randomized to be intubated either by a) VieScope or b) conventional direct laryngoscopy.
- Trial name
- VieScOP (NCT04724408)
- Testing
- VieScope, Conventional
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Contraception
Intrauterine Contraceptive Device (IUD) Placement at Time of C-Section
This is a pilot study of up to 10 women, which will test the hypothesis that the placement of copper IUDs through the uterine incision at the time of uncomplicated elective C-section is technically feasible and acceptable to…
- Trial name
- NCT00733278
- Testing
- Copper IUD ( ParaGard Intrauterine Contraceptive Device)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Wound Infection
A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections
The purpose of this study is to find out if chlorhexidine gluconate solution is better at reducing the rate of wound infection after cesarean section compared to povidone-iodine.
- Trial name
- NCT00528008
- Testing
- povidone-iodine solution, chlorhexidine gluconate
- Where
- Canada
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Minimally Invasive Coronary Revascularization Surgery, Elective Surgery
Impact of Total Coronary Revascularization Via Left Anterior Thoracotomy (TCRAT) vs. Robotic-Assisted Harvesting of LIMA (ITcrats)
The two types of total coronary revascularization via left anterior thoracotomy (TCRAT) might have their potential benefits and disadvantages.
- Trial name
- ITcrats (NCT06988735)
- Testing
- Nonrobotic TCRAT, Robotic TCRAT
- Where
- Saudi Arabia
- Volunteers
- 182 people
- Sponsor
- Mohamed R El Tahan
Diabetes, Gestational, Wound Complication
PRP Use in Diabetic Patients Undergoing Cesarean Section
this study will investigate the effectiveness of PRP in wound healing among diabetic patients undergoing elective cesarean sections
- Trial name
- NCT03602950
- Testing
- PRP
- Volunteers
- 100 people
- Sponsor
- Minia University
Pregnancy, Obesity
Investigation of Continuous Versus Interrupted Subcutaneous Fat Closure in Reducing Surgical Site Infection
This research aims to clarify the best way to perform subcutaneous tissue closure in overweight and obese patients undergoing caesarean section to reduce the occurrence of surgical site infections.
- Trial name
- NCT05856968
- Testing
- continuous subcutaneous tissue closure, Interrupted subcutaneous tissue closure
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Acute Pain, Total Hip Arthroplasty
Auricular Acupuncture for Analgesia During Total Hip Arthroplasty
The aim is to investigate whether auricular acupuncture is superior to sham acupuncture in relief of acute pain and in reduction of analgesics in patients during total hip arthroplasty
- Trial name
- NCT00334165
- Testing
- Auricular acupuncture (procedure)
- Where
- 2 sites in Germany
- Volunteers
- 360 people
- Sponsor
- University Medicine Greifswald
Neonates, Infants Aged 0 Days to 12 Months Scheduled for Elective Surgery
Upper Airway Ultrasound to Predict Difficult Laryngoscopy in Neonates and Infants
Upper airway ultrasound (UA-US) has been utilized in adults to predict difficult laryngoscopy (Cormick-Lehane view 3 or 4) and difficult tracheal intubation (DTI) (≥3 intubation attempts) and with moderate-to-high sensitivity and…
- Trial name
- NCT07444528
- Testing
- Upper airway ultrasound
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Idiopathic Scoliosis
Evaluation of Analgesia for Spine Fusion Elective Surgery in Children
The multicenter PRECISE Analgesia (Prospective Randomized Evaluation of Analgesia for Idiopathic Scoliosis Spine Fusion Elective Surgery in Children) trials will a) implement and investigate the efficacy and safety of multidose…
- Trial name
- PRECISE (NCT06626503)
- Testing
- Methadone based ERAS, Non-methadone based group
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Senthil Sadhasivam
Coronary Artery Disease
STEEL Percutaneous Coronary Intervention
The principal hypothesis of this study is that two different maintenance regimens of ticagrelor are safe, tolerable and associated with significant inhibition of erythrocyte adenosine reuptake compared to clopidogrel in patients…
- Trial name
- STEEL-PCI (NCT02327624)
- Testing
- Clopidogrel, Ticagrelor 60, Ticagrelor 90
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Hemorrhage; Complicating Delivery, Coagulation Defect
The Effect of Human Albumin on Coagulation Competence and Hemorrhage
In a randomized clinical trial, the purpose is to investigate if perioperative coagulation and hemorrhage is influenced by colloid or crystalloid.
- Trial name
- NCT02270723
- Testing
- 5% Human Albumin " Behring", Lactated Ringer
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kirsten Cleemann Rasmussen
Laparoscopic Cholecystectomy
Nerve Blocks vs Local Injections for Post-op Pain Prevention in Laparoscopic Cholecystectomy in Children
The objective of this study is to compare transversus abdominis plane (TAP) blocks to local wound infiltration (LWI) in terms of postoperative pain control in pediatric patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- NCT03022279
- Testing
- TAP Blocks, local wound infiltration
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Brian Wallace Gray
IBD - Inflammatory Bowel Disease
Trial Comparing Multiport RObotic and Laparoscopic Surgery for Elective Colorectal Resections in IBD Patients (ACRO-IBD)
The aim of this study is to better understand whether robotic surgery leads to better outcomes than laparoscopy in terms of complications, recovery and quality of life.
- Trial name
- ACRO-IBD (NCT07230262)
- Testing
- Robotic colorectal surgery, Laparoscopic colorectal surgery
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cognitive Impairment, Postoperative Delirium
Cognitive Impairment Following Elective Spine Surgery
Older people are a rapidly growing proportion of the world's population and their number is expected to increase twofold by 2050.
- Conditions
- Cognitive Impairment, Postoperative Delirium, Spine Fusion
- Trial name
- CONFESS (NCT03486288)
- Where
- Germany
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Post-induction Hypotension (PIH)
Preoperative Caval-Aortic Index and Pleth Variability Index for Predicting Post-Induction Hypotension in Colorectal Surgery
This prospective observational study evaluated whether the preoperative caval-aortic index and pleth variability index can predict post-induction hypotension in adult patients undergoing elective colorectal surgery under general…
- Trial name
- NCT07876362
- Testing
- Preoperative Caval-Aortic Index and Pleth Variability Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
General Anesthesia
Safety and Efficacy of HSK3486 Compared to Propofol for Induction of General Anesthesia in Adults With Elective Surgery
To demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous [IV] slow injection over 30 [±5] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to Propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection…
- Trial name
- NCT05486416
- Testing
- HSK3486, Propofol
- Where
- 28 sites in United States, Poland and 1 more
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
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