Clinical trials: Surgical Procedures, Elective
Hypotension Symptomatic, Vasoconstriction
Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section
This will be a double-blind randomized study, aiming at investigating a fixed rate phenylephrine infusion versus a fixed rate norepinephrine infusion versus placebo in combination with co-hydration with colloids for the…
- Conditions
- Hypotension Symptomatic, Vasoconstriction, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- annie-zoe (NCT04404946)
- Testing
- phenylephrine infusion, norepinephrine infusion
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Aretaieion University Hospital
Preeclampsia
Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia
This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective…
- Trial name
- NCT02699827
- Testing
- Levobupivacaine hydrochloride, Magnesium sulphate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Sayed Abdelhafez
Carotid Endarterectomy
Monitoring Brain Perfusion and Cerebral Oximetry in Carotid Endarterectomy Surgeries
The goal of this study is to demonstrate Or-Nim's CerOx monitor ability to monitor changes in cerebral blood flow and oximetry during CEA surgery.
- Trial name
- CerOx (NCT02102386)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Blood Loss
Compare Between the Effect of Topical Tranexamic Acid Versus Hydrogen Peroxide on Blood Loss in Spine Surgeries
To evaluate the effectiveness of topical TXA in reducing blood loss compared to H2O2 wash. The primary outcomes : 1. Estimation of Intraoperative blood loss and blood transfusion. 2. Recording Postoperative blood drainage. 3.
- Trial name
- Bloodloss (NCT05152186)
- Testing
- Topical Solution, Topical Foam, Topical
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Minia University
Head and Neck Cancer
Dose De-escalation to the Elective Nodal Sites in Head and Neck Cancer
A randomized clinical trial was initiated to investigate whether a reduction of the dose to the elective nodal sites and the swallowing apparatus delivered by IMRT would result in a reduction of acute and late side effects…
- Trial name
- NCT01812486
- Testing
- dose de escalation, standard dose
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Supraglottic Airway Device
A Comparison of the I-gel and Self-pressurised Air-Q Intubating Laryngeal Airway (Air-Q sp) in the Elderly Patients
Supraglottic airway devices (SADs) are well established in anesthetic practice. Among these devices, the i-gel has been typically widely used.
- Trial name
- NCT02260427
- Testing
- Insertion of the i-gel, Insertion of the air-Q sp
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Anesthesia, Shoulder Pain
Dexmedetomidine Added to Ropivacaine Single Shot vs Continuous Interscalene Nerve Block
Arthroscopic shoulder surgery is increasingly performed in an outpatient setting and post-operative pain management is often a real challenge as those surgeries are well recognized for their high level of pain which often affects…
- Conditions
- Anesthesia, Shoulder Pain, Post Operative Pain
- Trial name
- DEXBIB (NCT05775861)
- Testing
- single shot interscalene brachial plexus block group with dexmedetomidine added to ropivacaine group, continuous interscalene brachial plexus block
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Wound Infection
A Trial Comparing Stapled Versus Monocryl Sutured Skin Closure for Elective Open Colectomy
Background Stapled skin closure is frequently performed following open colectomies. However, its pain and cosmetic outcomes have been suboptimal.
- Trial name
- NCT01907542
- Testing
- stapled skin closure, monocryl skin suture
- Where
- Singapore
- Volunteers
- 144 people
- Sponsor
- National University Hospital, Singapore
Laparoscopic Cholecystectomy, Postoperative Pain
RIPB Versus EOIPB for Pain Control After Laparoscopic Cholecystectomy
This prospective observational study aims to compare the effects of bilateral ultrasound-guided recto-intercostal plane block(RIPB) and bilateral ultrasound-guided external oblique intercostal plane block(EOIPB) on postoperative…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Postoperative Analgesia
- Trial name
- RIPB-EOIPB (NCT07607262)
- Testing
- Bilateral Ultrasound-Guided Recto-Intercostal Plane Block, Bilateral Ultrasound-Guided External Oblique Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cardiac Surgical Procedures
Placement of Permanent Pacemaker Study
The purpose of this study is to determine the predictors for placement of permanent pacemakers soon after cardiac surgery. We will measure the following to see what influence, if any, they have on predicting the need for…
- Trial name
- NCT00512161
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Weill Medical College of Cornell University
Premedication, Endotracheal Intubation
Premedication Trial for Tracheal Intubation of the NEOnate
Multicenter double blind randomized controlled trial comparing "atropine+propofol" vs "atropine+atracurium+sufentanil" as a premedication prior to endotracheal intubation of the neonate.
- Trial name
- PRETTINEO (NCT01490580)
- Testing
- atropine+ propofol, atropine + atracurium + sufentanil
- Where
- 6 sites in France
- Volunteers
- 173 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Rectal Cancer, Colon Cancer
Trial on Mechanical Bowel Preparation in Laparoscopic Colorectal Surgery
This is a Randomized trial on Mechanical Bowel Preparation in Laparoscopic Colorectal Surgery. In this trial patients with left sided colon and rectal tumors were randomized to receive mechanical bowel preparation or no…
- Trial name
- MBP (NCT01797770)
- Testing
- polyethylene glycol, No Preparation
- Where
- India
- Volunteers
- 90 people
- Sponsor
- PVS Memorial Hospital
Neurocognitive Disorders, HbA1c
HbA1c and Neurocognitive Disorders
Preliminary evidence suggest a possible relationship between HbA1c and perioperative neurocognitive disorders (NCD). We are going to investigate whether the preoperative value of HbA1c in patients undergoing elective non-cardiac…
- Trial name
- NCT04736277
- Testing
- Preoperative HbA1c
- Where
- Greece
- Volunteers
- 288 people
- Sponsor
- University of Thessaly
Perioperative Complication, Cardiovascular Complication
Cardiovascular Outcomes and Mortality in Vascular Surgical Patients
This is a registry-based study of elective vascular surgical patients undergoing intermediate or high-risk vascular surgical interventions at Groote Schuur hospital, a tertiary academic center, over a 12 month period.
- Trial name
- NCT05208957
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 175 people
- Sponsor
- University of Cape Town
Adult Participants Requiring Tracheal Intubation Under General Anesthesia for Elective Surgery
Efficacy and Safety of HRS-9190 in General Anesthesia
A multicenter, randomized, double - blind, placebo - controlled, parallel - group phase III clinical trial was carried out to evaluate the efficacy and safety of HRS - 9190 for skeletal muscle relaxation during tracheal…
- Trial name
- NCT07733245
- Testing
- Administration of intravenous HRS-9190, Administration of intravenous rocuronium
- Where
- China
- Volunteers
- 320 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pain, Postoperative
The PENG Block in Elective Hip Surgery and Its Effect on Postoperative Pain and Length of Stay.
Effective postoperative pain management in elective hip surgery is crucial for the patients well-being, rapid mobilisation and potential reduction of length of stay.
- Trial name
- NCT05056675
- Testing
- PENG block
- Where
- Switzerland
- Volunteers
- 151 people
- Sponsor
- Hôpital Fribourgeois
Cardiac Surgery, Cardiopulmonary Bypass
Voluven® in Paediatric Patients
This study will compare the clinical efficacy and safety of Voluven® and Human Albumin during elective open-heart surgery in pediatric patients.
- Trial name
- NCT00860405
- Testing
- HES 130/0.4 (6%) in sodium chloride (Voluven®, solution for infusion), Human serum albumin (HSA 50g/L), Human serum albumin (HSA 50g/L)
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 61 people
- Sponsor
- Fresenius Kabi
Pain, Breast Diseases
T3AI-Pain After Breast Surgery
Current standard of care for post-operative analgesia after breast surgery in CDHA is Tylenol #3® (300 mg acetaminophen, 30 mg codeine, 15 mg caffeine per tablet).
- Trial name
- T3AI (NCT00299039)
- Testing
- acetaminophen plus codeine, acetaminophen plus ibuprofen
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Cardiovascular, Coronary Artery Bypass
A Single-centre Study Comparing a Non-invasive Lactate Sensor to Standard Invasive Measurements in Patients Undergoing Coronary Artery Bypass Surgery.
The main goal of this study is to see how well a non-invasive lactate sensor measures lactate levels compared to standard blood tests.
- Conditions
- Cardiovascular, Coronary Artery Bypass, Valve Replacement
- Trial name
- CONTINUUM L (NCT06597253)
- Testing
- Lactate sensor
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Queen Mary University of London
Coronary Artery Disease
Effects of Cangrelor on MIcRovAscular Disfunction During Elective Percutaneous CORonary Intervention
Dual Antiplatelet Therapy represents the main therapy for patients presenting with chronic coronary syndromes and undergoing elective PCI.
- Trial name
- MIRACOR (NCT06089577)
- Testing
- Cangrelor 50 MG
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Federico II University
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