Clinical trials: Surgical Procedures, Elective
Gallstones, Cholelithiasis
RCT: Multi-modal Analgesia for Laparoscopic Cholecystectomy
Analgesic efficacy of multi-modal analgesia is superior to standard analgesia for patients undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
- Conditions
- Gallstones, Cholelithiasis, Pain
- Trial name
- LapChole (NCT01972620)
- Testing
- Bupivacaine
- Where
- Serbia
- Volunteers
- 63 people
- Sponsor
- Klinicki Centar Vojvodine
Analgesia Disorder
Transverse Abdominal Block for Analgesia in Casarean Section
In this study, the investigators will compare the analgesic effect of bupivacaine and bupivacaine-dexmetomedine after elective cesarean delivery by performing an bilateral TAP block, on the patients for whom the operation will be…
- Trial name
- NCT02122510
- Testing
- Bupivacine group, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Post-Dural Puncture Headache
Comparison of Nebulized Neostigmine/Atropine Versus Lignocaine in Treating Acute Post-dural Puncture Headache Following Subarachnoid Block in Parturient Undergoing Elective Cesarean Section. A Randomized, Clinical Trial.
Post-dural puncture headache (PDPH) is a common and debilitating complication of spinal anesthesia in pregnant patients undergoing cesarean sections, with an incidence ranging from 0.5% to 2% (1).
- Trial name
- NCT06824025
- Testing
- lidocaine group ( nebulized lidocaine + saline) total volume 4 ml
- Where
- Egypt
- Volunteers
- 111 people
- Sponsor
- Minia University
Ovarian Cancer, Cholecystolithiasis
Safety of Opportunistic Salpingectomy During Elective Laparoscopic Cholecystectomy.
The knowledge, coupled with epidemiological studies demonstrating lower ovarian cancer rates in women with a history of tubal sterilization has led to recommendations for opportunistic salpingectomy at the time of benign…
- Trial name
- NCT07642791
- Testing
- Opportunistic salpingectomy, Cholecystectomy
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University of Zurich
Anesthesia, General, Memory
Depth of Anesthesia on Implicit Memory
Purpose of this study is to see if different levels of anesthesia have an effect on hearing spoken words without awareness of having heard them or anxiety after surgery.
- Trial name
- NCT00584324
- Testing
- BIS 40, BIS 60
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Oklahoma
Elective Reconstructive Surgery Population
The Effect of Healing Touch on Sleep
Healing Touch improves measures of sleep the night prior to surgery, thus improving surgery-related morbidity.
- Trial name
- Sleep7 (NCT01870076)
- Testing
- Healing Touch, Control, Presence
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
CABG, Dexmedetomidine
Role of Opioid Free Anaesthesia in Elderly Patients Undergoing Elective Coronary Artery Bypass Graft Surgeries With Cardiopulmonary Bypass in Enhanced Recovery After Surgeries
The introduction of synthetic opioids in 1960 to general anesthesia together with sedative hypnotics and muscle relaxants allowed the appearance of the concept of multimodal balanced anesthesia.
- Conditions
- CABG, Dexmedetomidine, Ketamine, Opioid Free Anesthesia
- Trial name
- NCT07360327
- Testing
- Opioid free anesthesia, Opioid based Anesthesia
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Elective Cesarean Section
The Clotting Effects of Pentastarch and Normal Saline in Obstetric Patients
Pregnant women are more likely to form clots than non-pregnant women as pregnancy increases the clotting factors present in the blood. This helps to prevent excess bleeding (hemorrhage) at the time of delivery.
- Trial name
- NCT00474162
- Testing
- Pentaspan®, Normal Saline
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Gallstone
Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies
Double blind RCT comparing elective laparoscopic cholecystectomy using warmed, humidified gas (new) against laparoscopic cholecystectomy with cool, dry gas (usual). Sample size of 200 patients.
- Trial name
- NCT00792389
- Testing
- Warm humidified C02, Cool dry C02
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Pennine Acute Hospitals NHS Trust
This Study Mainly Focus on the Eras Protocol Decreasing Time of Npo and Early Discharge From Hospital to Avoid Hospital Acquired Infections
A Comparative Study of Preoperative Carbohydrate Loading Dose and Fasting on Postoperative Recovery Time in Elective Abdominal Surgery Patients
This randomized controlled trial aims to compare the effect of preoperative carbohydrate loading versus standard overnight fasting on postoperative recovery time in patients undergoing elective abdominal surgery.
- Trial name
- NCT07562776
- Testing
- Patients will be given 400 mL of a carbohydrate-rich clear drink (10% daxtrosewater) approximately 2-3 hours before induction of anesthesia, according to ERAS guidelines., Standard pre operative fasting
- Volunteers
- 144 people
- Sponsor
- Gulab Devi Hospital
Gastric Content Aspiration Risk, Gastrointestinal Endoscopy
BBCMADE Nomogram Validation for High-Risk Gastric Content in Sedative Endoscopy
This prospective observational study aims to validate the BBCMADE nomogram (Body Mass Index, Brain infarction, Cirrhosis, Male sex, Age, Diabetes, Esophageal reflux) for predicting high-risk gastric content in patients undergoing…
- Conditions
- Gastric Content Aspiration Risk, Gastrointestinal Endoscopy, Anesthesia Complications
- Trial name
- BBCMADE (NCT07638917)
- Testing
- BBCMADE Nomogram, Endoscopic Gastric Volume and pH Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 533 people
- Sponsor
- Fusun Gozen
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
Endometritis
The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section
Objective: To determine the optimal time for intravenous antibiotic prophylaxis administration in pregnant women undergoing elective cesarean section to minimize postpartum infectious complication for both the mother \& neonate.
- Trial name
- NCT02742948
- Testing
- ceftriaxone
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cairo University
Colorectal Cancer (Diagnosis)
Effects of a WhatsApp-assisted Prehabilitation for Patient Undergoing Elective Colorectal Cancer Surgery
The goals of this study is to evaluate the feasibility and the effects of a WhatsApp-assisted prehabilitation for colorectal cancer patients undergoing elective surgery.
- Trial name
- NCT07376668
- Testing
- Intervention, Standard care
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Surgical Procedures, Elective, Nurse Based Care Management
The Effect of White Noise Sleep Mask on Patients' Sleep Quality and Comfort After Transurethral Resection of the Prostate (TUR-P) Surgery
One of the greatest challenges patients face in the postoperative period is the deterioration of sleep quality. Decreased sleep quality in the postoperative period is commonly observed due to pain, stress, anxiety, hospital…
- Trial name
- NCT06936384
- Testing
- In this group, patients will be provided with a white noise sleep mask in accordance with the protocol determined for the postoperative period. Patients will sign an informed voluntary consent form be
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
High Risk Pregnant Women Undergoing Elective Cesarean Section
The Prophylactic Role of Tranexamic Acid in High Risk Pregnant Women Undergoing Elective Cesarean Section in Prevention of Postpartum Hemorrhage
The aim of the study is to assess the prophylactic role of tranexamic acid in reducing blood loss during and after elective cesarean section delivery in high risk patients.
- Trial name
- NCT05434533
- Testing
- Tranexamic acid (Kapron, Amoun Pharmaceuticals SAE, Egypt. 5ml Amp, 100mg /1ml)
- Where
- Egypt
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Cairo University
Esophageal Squamous Cell Carcinoma
Involved Field Irradiation (IFI) Versus Elective Nodal Irradiation (ENI) for Esophageal Cancer
This study examines contrast advantages and disadvantages of elective or prophylactic nodal irradiation in the treatment of esophageal cancer with three-dimensional conformed radiotherapy.
- Trial name
- NCT01551589
- Testing
- Involved Field Irradiation(IFI), docetaxel and cisplatin, Elective Nodal Irradiation (ENI)
- Where
- 4 sites in China
- Volunteers
- 220 people
- Sponsor
- Chengya Chou
Cesarean Section Complications, Tranexamic Acid
Comparing Intramyometrial Tranexamic Acid and Oxytocin for Blood Loss in Cesarean Section
Cesarean section is the most prevalent operation among women globally, 10-15% (1, 2). Recent research has shown Egypt to be the third-largest country globally, with an estimated 52% cesarean sections (3).
- Conditions
- Cesarean Section Complications, Tranexamic Acid, Oxytocin, Post Partum Hemorrhage
- Trial name
- NCT06010368
- Testing
- Tranexamic acid injection, Oxytocin
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Post Partum Hemorrhage
Tranexamic Acid Versus Sublingual Misoprostol in Reducing Blood Loss During Elective CS in High Risk Cases
The Efficacy and safety of Preoperative Intravenous Tranexamic acid versus Sublingual misoprostol in reducing blood loss during and after Elective Cesarean section among high risk pregnant cases.
- Trial name
- NCT04117243
- Testing
- Misoprostol, Tranexamic acid, Oxytocin
- Where
- Egypt
- Volunteers
- 345 people
- Sponsor
- Cairo University
Anesthesia; Sexual, Analgesia
The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section…
- Trial name
- NCT05758233
- Testing
- Patients undergoing transversalis fascia plane block, Patients undergoing transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
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