Clinical trials: Surgical Procedures, Elective
Surgery Complications
The ACCELERATE Pilot Trial
The Advancing Cognition and Cognitive reserve before ELective surgery to Enhance cognitive Recovery And TrajEctories (ACCELERATE) Pilot Trial estimates whether our novel, coach-supported cognitive prehabilitation strategy will…
- Trial name
- NCT07655414
- Testing
- Cognitive Prehabilitation
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- Ottawa Hospital Research Institute
Elective Cranial Procedures With Dural Incision
DuraSeal Sealant Post Market Study
DuraSeal Dural Sealant has been approved as a dural sealant by the FDA for use in cranial and spinal procedures. This study was completed to further evaluate the safety of the DuraSeal Sealant in a post-approval setting as…
- Trial name
- NCT00704340
- Testing
- DuraSeal Dural Sealant System, Standard of Care
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- Integra LifeSciences Corporation
Acute Kidney Injury, Hepatectomy
Renal Oxygenation-Guided AKI Reduction Trial
Acute kidney injury (AKI) is a common complication after major liver surgery. This study will evaluate whether intraoperative management guided by renal regional oxygen saturation (RrSO₂), measured using near-infrared…
- Trial name
- ROGAR (NCT07816640)
- Testing
- INVOS 5100C regional oxygen saturation monitoring system, RrSO2-guided perioperative management, Usual perioperative management
- Where
- 20 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Chinese PLA General Hospital
Patients Undergoing Elective Surgery With Anesthesia
Telemedical Risk Assessment and Preoperative Evaluation (TAPE)
The purpose of this study is to assess the feasibility, patient satisfaction and time saving of a telemedical risk assessment and preoperative evaluation for anesthesia.
- Trial name
- NCT04518514
- Testing
- TAPE-Software
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Cardiovascular Bleeding, Vascular Bleeding
The Bioseal Vascular Study
To evaluate the clinical utility of Bioseal as an adjunct to control bleeding during elective vascular surgery.
- Conditions
- Cardiovascular Bleeding, Vascular Bleeding, Hemorrhage
- Trial name
- NCT02094885
- Testing
- Bioseal Fibrin Sealant, Manual Compression
- Where
- 9 sites in China
- Volunteers
- 252 people
- Sponsor
- Ethicon, Inc.
Infertility, Female
Preimplantation Genetic Testing in Women of Advanced Maternal Age
The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo transfer in women between 35 and 40…
- Trial name
- GETSET (NCT04167748)
- Testing
- Preimplantation genetic testing for aneuploidy (PGT-A)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Genomic Prediction Inc.
Diverticulitis
Recurrence Following Nonoperative Management of 1st Episode of Hinchey II Diverticulitis
Patients will agree to be randomized to either surgery or observation following nonoperative management of a first episode of Hinchey II diverticulitis.
- Trial name
- NCT01986686
- Testing
- Colon resection
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Stony Brook University
Surgical Site Infections
Effect of Mupirocin Dressings Versus Island Dressings on Surgical Site Infections in Elective Colorectal Surgery
Infections at the site of surgical incisions (SSIs) are the most common infection among surgical patients. Although all patients undergoing surgical procedures are at risk for developing SSIs, colorectal surgery has had…
- Trial name
- NCT02619773
- Testing
- mupirocin ointment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Pain, Postoperative
Study of Indomethacin Capsules to Treat Pain Following Surgery in Children Ages 6 to <17 Years of Age
The purposes of this study are to evaluate the safety and tolerability and to model the single-dose pharmacokinetic profile of indomethacin capsules low dose and high dose in children ages 6 to <17 years experiencing mild to…
- Trial name
- NCT02633969
- Testing
- Indomethacin Capsules low dose, Indomethacin Capsules high dose
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Cesarean Section, Informed Consent
Physician vs Artificial Intelligence Counseling Before Elective Cesarean Delivery: A Randomized Controlled Trial
This randomized controlled trial will compare two methods of providing preoperative counseling before elective cesarean delivery: counseling by an obstetrician-gynecologist and counseling delivered through an artificial…
- Conditions
- Cesarean Section, Informed Consent, Anxiety
- Trial name
- CAI-CS (NCT07762534)
- Testing
- Physician-Delivered Counseling, AI-Based Counseling
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Wolfson Medical Center
Quality of Recovery After Mastectomy, Serratus Anterior Plane Block
Timing of Serratus Anterior Plane Block in Mastectomy Surgery
Postoperative pain following mastectomy may adversely affect early mobilization, patient comfort, and overall quality of recovery.
- Conditions
- Quality of Recovery After Mastectomy, Serratus Anterior Plane Block, Postoperative Pain, Mastectomy
- Trial name
- NCT07661212
- Testing
- Ultrasound-Guided Serratus Anterior Plane Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Painrelief, Postoperative
Rectal Versus Intramuscular Diclofenac for Pain Relief Following Caesarean Section
Caesarean section (CS) is one of the commonest major Obstetric surgeries worldwide and its rate has markedly increased globally.
- Trial name
- NCT06845930
- Testing
- Rectal Diclofenac, Intramuscular diclofenac
- Where
- Nigeria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assumpta Nnenna Nweke
Arthroplasty, Knee Replacement, Replacement, Total Knee
ChloraPrep Versus Betadine for Elective Knee Replacement Surgery
This study will enroll patients who will be receiving primary total knee replacements. Subjects will be randomized into two groups: Betadine surgical scrub preparation and ChloraPrep preparation prior to total knee replacements.
- Conditions
- Arthroplasty, Knee Replacement, Replacement, Total Knee, Total Knee Replacement
- Trial name
- NCT01184196
- Testing
- Swab area with Betadine, Swab area with ChloraPrep
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Central DuPage Hospital
Pregnancy
Elective Induction of Nulliparous Labor
Primary outcome: to evaluate the effect of elective induction of labor (IOL), at 39 weeks gestation, on cesarean delivery rates in nulliparous women compared to expectant management (EM).
- Trial name
- NCT01076062
- Testing
- Induction of Labor
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Polycystic Ovary Syndrome, Infertility
Live Birth After Fresh Embryo Transfer Vs Frozen-thawed Embryo Transfer in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of childbearing age. However, the optimal infertility treatment for PCOS patients is still a matter of controversy.
- Trial name
- FreFro-PCOS (NCT01841528)
- Testing
- fresh embryo transfer, frozen-thawed embryo transfer
- Where
- 14 sites in China
- Volunteers
- 1,180 people
- Sponsor
- Zi-jiang Chen
Elective Surgery
Does American Society of Anesthesiologists (ASA) Physical Status Scale Enough in Patients Assessment
American Society of Anesthesiologists (ASA) physical status scale has been used worldwide for assessing the status of patients before operation.
- Trial name
- ASAINPA (NCT00776880)
- Testing
- ASA scale, PPS scale
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Nanjing Medical University
Total Knee Replacement Surgery
The Impact of Sedation Depth Monitoring for Cognitive Functions and Early Rehabilitation After Major Joints Arthroplasty
Spinal anesthesia is applied for patients undergoing total elective knee replacement surgery. It reduces rates of postoperative complications, improves postoperative pain management, rehabilitation is started earlier and patients…
- Trial name
- NCT06241859
- Testing
- Dräger Infinity Delta series monitor (Dräger, Germany) with Covidien BIS LoC 2 channel module and BIS Quatro (4 electrodes) sensor (Covidien, Ireland)
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Inadequate or Impaired Breathing Pattern or Ventilation
Supreme LMA and Proseal LMA in Prone Anesthetized Patient
There is no significant difference about success rate of two devices.
- Trial name
- SPLMA (NCT01814306)
- Testing
- Supreme LMA, Proseal LMA
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Severty of Hpotention
Comparing Sitting Versus Lateral Position During Spinal Anesthesia on the Severity of Hypotension:
This study aimed to assess the effect of sitting and lateral positions on the severity of hypotension during the initiation of spinal anesthesia in elective cesarean section. There will be Sitting and Lateral groups in the study.
- Trial name
- NCT06149572
- Testing
- lateral position procedure, sitting position porocedure
- Where
- Ethiopia
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Wollo University
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