Clinical trials: Surgical Procedures
Osteoarthritis, RA
Surgical Tourniquets and Cerebral Emboli
BACKGROUND In 2012 76,497 primary total knee (TKR) replacements were performed in England, Wales and Northern Ireland . Traditionally TKR surgery is undertaken with the aid of a surgical tourniquet.
- Conditions
- Osteoarthritis, RA, Trauma
- Trial name
- NCT02240732
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Abortion in First Trimester, Pain, Procedural
Ketamine Versus Fentanyl for Surgical Abortions
Ketamine is commonly used for procedural sedation and analgesia. It is widely used for trauma cases in the emergency department and is considered a superior agent in the outpatient setting due to its lack of respiratory and…
- Conditions
- Abortion in First Trimester, Pain, Procedural, Opioid Use
- Trial name
- NCT04871425
- Testing
- Ketamine, Fentanyl
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain Control
Gabapentin for Perioperative Pain Relief in Surgical Abortion
Gabapentin preoperative use for evaluation of benefit to reduce pain during and after surgical office-based abortion.
- Trial name
- NCT04292171
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Shivering
Assessment Of Shivering With iSeismograph
Shivering is a common side-effect of epidural anesthesia. In studies to date, the assessment of shivering has been based on a simple scale using descriptive words rather than actual measurements.
- Trial name
- NCT02436174
- Testing
- novel device
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Maxillary Diseases
Photobiomodulation Effects on Pain, Edema, Paresthesia and Bone Regeneration After Maxillar Surgical Disjunction
The objective of the present study will be to evaluate the efficacy of photobiomodulation (PBM) with LED in pain control, facial edema, paresthesia, bone repair and quality of life arising after maxillar surgical disjunction…
- Trial name
- NCT03814525
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Hernia of Abdominal Wall, Incisional Hernia
"BP as a New Device for Surgery and Solid Cancer and Hematopoietic System Tumors Treatment. Effects of BP Implantation"
Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias in humans, in laparotomic procedures and as a new device…
- Trial name
- DM159 (NCT02328352)
- Testing
- BP selfstanding felt, PP mesh, BP intraperitoneal mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Hernia, Incisional Hernia
"Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and Laparoscopic
"Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias, diaphragmatic hernias, diaphragmatic rupture…
- Trial name
- 36P (NCT02137018)
- Testing
- PPL fixation by BP, PPL mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Healthy
Virtual Reality Educational Intervention for Nursing Students' Day Surgery Patient Counselling
This pilot feasibility study evaluates whether a virtual reality (VR) educational program can help nursing students develop better skills for counseling day surgery patients.
- Trial name
- CINDY (NCT07305714)
- Testing
- CINDY Virtual Reality Educational Intervention
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seinajoki University of Applied Sciences
Chronic Rhinosinusitis (Diagnosis), Cohort Study
A Prospective Single-center Cohort Study of Surgical Treatment of Chronic Rhinosinusitis
Chronic Rhinosinusitis (CRS) is a common and frequent disease in otorhinolaryngology. The main symptoms of patients include nasal congestion, runny nose, swelling pain of the frontal area and decreased sense of smell.
- Conditions
- Chronic Rhinosinusitis (Diagnosis), Cohort Study, Evidence-based Medicine
- Trial name
- NCT06010316
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Surgical Site Infections
Review of Surgical Site Infection Registration Routine at Surgery Departments in Sweden and Validation of One of the Used Routines
This study explores the routines of registration of surgical site infections (SSI) at different surgical centers in Sweden. It explores the sensitivity and specificity of the registration routines of SSI are at Halmstad County…
- Trial name
- NCT01971138
- Testing
- this is a survey
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Halmstad County Hospital
Iron-deficiency, Anemia
Non-invasive Diagnostics of Iron Deficiency in Surgical Patients by Measuring Zinc Protoporphyrin-IX
In approx. 40% of the incidences anemia is caused by iron deficiency (= ID). In turn, preoperative iron-deficiency anemia (= IDA) is associated with an increase in morbidity and mortality as well as with the need for a blood…
- Conditions
- Iron-deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT03071497
- Testing
- Non-invasive analysis of Zinc protoporphyrin
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Combat and Operational Stress Reaction
Role of Stress Reduction Protocol on Outcome of Periodontal Therapy
Psychological conditions, particularly psychosocial stress, have been implicated as risk indicators for periodontal disease. Minimal evidence in literature exists to assess the effect of stress reduction therapy (SRT) in the…
- Trial name
- NCT02487862
- Testing
- Stress Reduction Protocol
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Aneurysm Aortic Root, Aortic Valve, Bicuspid
Aortic Valve Dynamics During Exercise After Valve Sparing Root Replacement Surgery
Aortic valve sparing operations are applied in patients with a non-calcified tricuspid or bicuspid aortic valve associated with a root aneurysm, in order to preserve the valve, and avoid new aortic dilatation by stabilizing the…
- Trial name
- NCT04205474
- Testing
- graded bicycle test
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Crohn's Disease, Inflammatory Bowel Disease
A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques
Postoperative pain can pose significant challenges in the postoperative recovery of patients undergoing major colorectal surgery. Traditionally, opioids have played an important role in treating postoperative pain.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Postoperative Pain
- Trial name
- NCT02538679
- Testing
- US TAP Bupivacaine/Epinephrine, Lap TAP Bupivacaine/Epinephrine
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Anesthesia, General
A Study to Assess Indices of SNAP vs VISTA on Surgical Patients Undergoing General Anesthesia
Establish the range of index values for the SNAP II corresponding to each anesthetic state studied.
- Trial name
- Precision GA (NCT00829803)
- Testing
- SNAP monitor; Bispectral Index Monitor (BIS Monitor)
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stryker Instruments
Healing Surgical Wounds, Pain
L-PRF vs PBM on Extraction Socket Healing
The aim of this study is to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and…
- Trial name
- NCT06328413
- Testing
- photobiomodulation, Leukocyte and Platelet Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung
Reconstructive Surgical Procedure
Nonincised Papillae in the Treatment of Intrabony Defects.
The primary objective of the present study is to clinically and radiographically evaluate nonincised papillae surgical approach and entire papilla preservation approach for the treatment of intrabony defects with GTR membrane and…
- Trial name
- NCT04376450
- Testing
- Experimental- Nonincised papillae surgical approach, Active comparator- Entire papilla preservation technique
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Periodontitis, Diabetes Mellitus
Efficacy of Hydrogen Peroxide Gel on Periodontitis With Diabetes
Periodontitis is a chronic infectious disease characterized by loss of tooth supporting periodontal structures and alveolar bone. In the U.S. and worldwide, periodontitis is the major cause of tooth loss in adults.
- Trial name
- Peroxide gel (NCT05669560)
- Testing
- PerioProtect ™= plastic tray +1.7% hydrogen peroxide
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Healing Wound, Iron-deficiency
Impact of Iron Stores on Wound Healing in Plastic Surgery
In breast reduction surgery, delayed wound healing may increase surgical site infections, cutaneous necrosis and may be related to psychological harm.Some risk factors have been identified : smoking, diabetes, overweight.
- Conditions
- Healing Wound, Iron-deficiency, Surgical Wound
- Trial name
- IRONPLAST (NCT04276168)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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