Clinical trials: Surgical Resection
Prevention, LARS - Low Anterior Resection Syndrome
Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)
The main aim of this randomized study will be to determine the effectiveness of pelvic floor exercises on the incidence or severity of LAR syndrome in patients after mini-invasive rectal resection.
- Conditions
- Prevention, LARS - Low Anterior Resection Syndrome, Pelvic Floor Disorders, Rectal Cancer
- Trial name
- CH1 (NCT06519006)
- Testing
- Pelvic floor exercise
- Where
- Slovakia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- F. D. Roosevelt University Hospital
Facial Swelling, Pain
Effects of Low-level Laser Therapy After Surgical Removal of Impacted Lower Third Molar
Goal: The aim of this study was to evaluate the effects of low-level laser (LLL) after surgical removal of impacted lower third molars (ILTM).
- Conditions
- Facial Swelling, Pain, Trismus
- Trial name
- NCT04280809
- Testing
- GaAlAs laser
- Where
- Vietnam
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Anastomotic Leak
Quantification of Anastomostic Blood Flow With Fluorescence Imaging in Low Anterior Resection for Rectal Cancer
A serious and life-threatening complication to rectal surgery is anastomotic leakage, AL. In Denmark, approximately 800 patients every year, are operated for rectal cancer, 50% of these with resection and anastomosis.
- Trial name
- FILAR (NCT05627934)
- Testing
- qICG
- Where
- Denmark
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Oral Complication
Effect of Piezoelectric Surgery on Pain, Comfort, and Patient Satisfaction in Third Molar Surgery
The purpose of this study is to compare the effects of piezoelectric surgery on postoperative pain, comfort and patient satisfaction with conventional bur method applied in surgical extraction of impacted mandibular third molars.
- Trial name
- NCT06971653
- Testing
- conventional surgery, piezoelectric surgery
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Anesthesia, Local
Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars
Control of postoperative pain is a foremost goal in achieving a satisfactory postoperative recovery. Surgical removal of lower third molars is accompanied by postoperative pain that is at its peak in the first 12 hours.
- Trial name
- NCT02353676
- Testing
- Bupivacaine, SALINE
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cosmozone Dental Clinic
Adenoma Colon, Serrated Polyp
Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions
This study compares the effectiveness in complete resection (absence of recurrence at 6 months) the two different techniques for performing endoscopic mucosal resection (EMR) of nonpedunculated homogeneous colorectal lesions >20mm
- Conditions
- Adenoma Colon, Serrated Polyp, Serrated Adenoma, Colorectal Neoplasms
- Trial name
- NCT04418843
- Testing
- Standard Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Spain
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Oscar Nogales
Plasma Cell Gingivitis
Management of Plasma Cell Gingivitis by Two Surgical Techniques
Two surgical protocols for management of Plasma cell Ginigivitis; either by surgical enblock resection of cold laser resection
- Trial name
- PCG (NCT05236322)
- Testing
- soft tissue laser
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Liver Diseases
Ischemic Preconditioning at a Distance in Liver Surgery
During hepatic transection, it exists a high risk of perioperative blood loss. The haemorrhage and its consequences (hypovolemia and blood transfusion) might impact the short and long term morbidity The vascular control by…
- Trial name
- HEPATOPROTECT (NCT04181502)
- Testing
- pneumatic tourniquet, No inflation
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Pain (Visceral, Somatic, or Neuropathic)
Postoperative Pain and Swelling After Flap vsFlapless Technique For Mandibular Third Molar Surgery
This randomized controlled trial evaluates postoperative pain and facial swelling following surgical removal of partially impacted mandibular third molars using flap versus flapless techniques.
- Trial name
- NCT07247929
- Testing
- flap technqiue for mandibular third molar extraction Arm A, flapless technquie arm b
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Benign Prostatic Hyperplasia
Comparison of H-FIRE and TURP in Treating Benign Prostatic Hyperplasia
This trial is comparing the effects and safety in treating men with benign prostatic hyperplasia between high freqnence irreversible electroporation and trans urethral resection prostate.
- Trial name
- NCT05306145
- Testing
- High freqnence Irreversible electroporation, Trans Urethral Resection Prostate
- Where
- China
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
Liver Cancer
Association Between Autologous Transfusion and Recurrence-free Survival in Patients With HCC After Resection
This prospective non-randomized controlled trial aims to determine whether autotransfusion of red blood cells salvaged before liver resection is associated with the recurrence-free survival in patients with hepatocellular…
- Trial name
- AT/HCC (NCT02654028)
- Testing
- Autotransfusion, Control group
- Where
- China
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Endoscopic Breast Surgery, Benign Breast Tumors
Endoscopic Extirpation of Benign Breast Tumors Using a Lateral Chest Wall Incision
1. A new surgical method for breast surgery has been introduced, which involves the removal of benign breast tumors through endoscopic surgery, thereby avoiding noticeable scarring on the breast. 2.
- Trial name
- NCT06472700
- Testing
- No intervention
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Gynecomastia
To Evaluate the Effectiveness and Safety of Single-port Robotic-assisted Subcutaneous Gland Resection in Males
The new technology of robotic surgery system, as an emerging technology, has shown certain application prospects in breast surgery.
- Trial name
- NCT07353411
- Testing
- Single-port Robotic-assisted Subcutaneous Gland Resection in males
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Progression-Free Survival, Overall Survival
Mesenteric Lymph Node Metastasis and Nutritional Status After Bowel Resection for Ovarian Cancer
Ovarian cancer is one of the three major malignant tumors in gynecology, causing more than 200,000 deaths globally each year, with the highest mortality rate.
- Conditions
- Progression-Free Survival, Overall Survival, Nutrition Aspect of Cancer
- Trial name
- NCT06527001
- Testing
- No intervention
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Skin Lesion
The Effect of Prophylactic Antibiotics on Surgical Site Infection Lower Limb Skin Excisions
The incidence of surgical site infection (SSI) infection in clean dermatologic surgery is very low, between 1-3%. Studies have demonstrated a much higher infection rate in skin excision surgeries in the lower limbs, up to 10% in…
- Trial name
- NCT03357419
- Testing
- Cephalexin
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pancreatic Neoplasms
Adjuvant Gemcitabine Versus Gemcitabine With Chemoradiation in Pancreatic Adenocarcinoma With R1 Resection and/or Positive Lymph Nodes
Adjuvant Gemcitabine Versus Gemcitabine With Chemoradiation in Pancreatic Adenocarcinoma With R1 Resection and/or Positive Lymph Nodes after curative resection.
- Trial name
- NCT02754180
- Testing
- Gemcitabine, TS-1 with radiation
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Hepatocellular Carcinoma
Research on Effectiveness and Safety of the Treatment, Hyperthermic Intraperitoneal Chemotherapy Combined With Tislelizumab and Targeted Therapy, That is Used for High-risk Hepatocellular Carcinoma After R0 Resection
There are limited treatment options for HCC with high recurrence risk, and there is no consistent plan for adjuvant therapy after surgery. Hence an unmet clinical need.
- Trial name
- NCT05546619
- Testing
- HIPEC+tislelizumab + targeted therapy
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sulai Liu
Colonic Fistula
Endoscopic Management Of Low Output Recurrent Colonic Fistula Or Leak After Anterior Resection For Rectal Cancer
This prospective randomized controlled clinical trial included all patients who developed the manifestations of low output recurrent colonic fistula or leak after colonic anterior resection for rectal cancer at Zagazig University…
- Trial name
- NCT05659446
- Testing
- endoscopy management of low output colonic fistula or leak after anterior resection for rectal cancer
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Bladder Cancer
FIRBladd - Use of Infrared Spectroscopy in the Diagnosis of Bladder Tumors
The purpose of this study is too assess infrared spectroscopy ability to discriminate urine of a patient affected by bladder cancer from urine of reference patient.
- Trial name
- FIRBladd (NCT02149862)
- Testing
- Urine infrared analysis
- Where
- France
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Colo-rectal Cancer, Polyp of Colon
Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy
The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps <=3mm during colonoscopy.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
- Trial name
- NCT04551001
- Testing
- Cold forcep polypectomy, Cold snare polypectomy
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Stanford University