Clinical trials: Surgical Resection
Rectal Cancer, Left Colic Artery Stenosis (Diagnosis)
Robotic-Assisted or Laparoscopic Radical Resection for Rectal Cancer With or Without Left Colic Artery Preservation
Brief Summary Background The preservation of the left colic artery (LCA) during rectal cancer resection remains a topic of controversy, and there is a notable absence of robust evidence regarding the outcomes associated with LCA…
- Conditions
- Rectal Cancer, Left Colic Artery Stenosis (Diagnosis), Robotic Assisted Laparoscopic Surgery
- Trial name
- NCT06376227
- Testing
- with or without Left Colic Artery Preservation
- Where
- China
- Volunteers
- 1,164 people
- Sponsor
- Northern Jiangsu People's Hospital
Efficacy, Complications
The Safety of Cataract Removal by Phacoemulsification Surgery in Patients Under Anti-aggregant and Coumadin Treatment
To assess the risks of intra- and postoperative bleeding tendency associated with cataract surgery by phacoemulsification in patients on coumadin and antiaggregant treatments. Design: Consecutive prospective study.
- Trial name
- NCT00564356
- Testing
- cataract surgery with phacoemulsification
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Sheba Medical Center
Hepatocellular Carcinoma
Radiofrequency Ablation Versus Liver Resection for Elderly Patients With Hepatocellular Carcinoma (HCC) Within the Milan Criteria
Hepatocellular carcinoma (HCC) is a common cancer, and it is the third commonest global cause of cancer-related death. With an increase in life-expectancy of the general population, the number of elderly with HCC is expected to…
- Trial name
- NCT01570075
- Testing
- HR, RFA
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Sun Yat-sen University
Esophageal Cancer, Colorectal (Colon or Rectal) Cancer
Quantitative Fluorescence Angiography With ICG for Perfusion Assessment During Surgery
The accurate assessment of intraoperative tissue perfusion is essential in any branch of surgery. Anastomotic leakage (AL) is one of the most feared complications following gastrointestinal surgery, with potentially threatening…
- Trial name
- SPY Q-ICG PAS (NCT05489757)
- Testing
- SPY Portable Handheld Imaging (SPY-PHI) System with SPY-QP Software
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- IRCCS San Raffaele
Pronlongated Alveolar Air Leak (PAAL)
Predictive Value of Intraoperative Ventilatory Leak Flow in Prolonged Alveolar Air Leak After Lung Resection Surgery
After lung resection surgery, patients usually receive a postoperative pleural drain. Prolongated alveolar air leak (PAAL) is a frequent complication after lung surgery (6 to 26% of patients), defined by the European Society of…
- Trial name
- AIR-LEAK (NCT03742739)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Pedunculated Colorectal Polyps, Haemorrhage
Underwater Endoscopic Mucosal Resection Versus Metal Clips With Hot Snare Polypectomy for Resection of Big Pedunculated Colorectal Polyps
Endoscopic resection of pedunculated polyps mainly focuses on how to prevent bleeding, and also needs to pay attention to the convenience of resection and the integrity of resection, which means that different endoscopic…
- Trial name
- NCT06097637
- Testing
- underwater endoscopic mucosal resection, hot snare polypectomy
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Ningbo No. 1 Hospital
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Prospective Study to Evaluate Outcomes From Transoral BOT Resection for OSAHS
This is a prospective observational study that will collect outcome data for patients who choose to undergo transoral tongue base operations for Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)as part of their standard of care…
- Trial name
- NCT01107795
- Testing
- Transoral Robotic Surgery
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Alabama at Birmingham
Urinary Bladder Neoplasms, Transurethral Resection
Ultrasound-Guided ONB for Transurethral Procedures - Interadductor Approach
Obturator nerve block is an effective method to prevent adductor muscles contraction during transurethral resection of bladder tumour localized on the lateral wall.
- Conditions
- Urinary Bladder Neoplasms, Transurethral Resection, Nerve Block
- Trial name
- NCT02696733
- Testing
- Ultrasound, lidocaine 2%, 0.9% Natrium Chloratum with a 2nd generation cephalosporin
- Where
- 2 sites in Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Colorectal Adenoma With Mild Dysplasia, Colorectal Adenoma With Severe Dysplasia
Piecemeal Versus En Bloc Resection of Large Rectal Adenomas
Currently, colonoscopy is the safest way to detect bowel tumors and polyps, since these can be biopsied and removed in one working process.
- Conditions
- Colorectal Adenoma With Mild Dysplasia, Colorectal Adenoma With Severe Dysplasia, Colorectal Adenomatous Polyp, Colorectal Low Grade Intraepithelial Neoplasia
- Trial name
- PERLA (NCT02238938)
- Testing
- en-bloc resection, piecemeal resection
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 110 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Carcinoma, Hepatocellular
Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection
This is a single-center, single-arm, open-label clinical study to evaluate the efficacy and safety of Adebrelimab plus Apatinib as adjuvant therapy in hepatocellular carcinoma (HCC) participants who are at high risk of recurrence…
- Trial name
- NCT06454578
- Testing
- Adebrelimab + Apatinib
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Qilu Hospital of Shandong University
Colorectal Cancer
Evaluation of Nexpowder Application to Prevent Delayed Bleeding After Colorectal Endoscopic Mucosal Resection
Delayed bleeding is the most frequent (5 to 15%) and challenging complication after large colorectal polypectomy. Different preventive treatments, such as the prophylactic use of clips, have been tried to prevent the occurrence…
- Trial name
- NEXBLEED (NCT05247515)
- Testing
- Endoscopic mucosal resection with nexpowder
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Gabriel RAHMI
Pancreatic Cancer
Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) and Pancreatic Function Following Surgery
The aim of this study will be to determine whether secretin-enhanced MRCP (S-MRCP) as well as traditional magnetic resonance imaging (MRI) of the pancreas will allow the investigators to quantify the pancreas' ability to secrete…
- Trial name
- NCT01094535
- Testing
- Synthetic Human Secretin
- Where
- United States
- Sponsor
- Columbia University
Locally Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer American Joint Committee on Cancer v8
PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy
This clinical trial tests how well surgical resection after chemotherapy given before surgery to make the tumor smaller (neoadjuvant) works to treat pancreatic cancer that has spread to nearby tissue or lymph nodes (locally…
- Conditions
- Locally Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer American Joint Committee on Cancer v8, Unresectable Pancreatic Adenocarcinoma
- Trial name
- NCT06132087
- Testing
- Biospecimen Collection, Computed Tomography, Distal Pancreatectomy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Southern California
Pancreas Adenocarcinoma, Pancreas Metastases
Pancreatic Cancer and Synchronous Liver Metastases Resection Following Neoadjuvant FOLFIRINOX
This is a prospective, pilot study from a single center. Patients will be evaluated and operated on by one of five surgeons with a subspeciality in hepato-biliary and pancreatic surgery.
- Conditions
- Pancreas Adenocarcinoma, Pancreas Metastases, Pancreas Cancer
- Trial name
- PDAC-LIV (NCT06349278)
- Testing
- Pancreatic resection and non-anatomic liver resections.
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Laval University
Maxillary Diseases
Schneider Membrane Preservation With In Situ Osteogenesis: A Modified Maxillary Resection Study
This case series study aimed to find out if a new surgical technique that preserves the sinus membrane during upper jaw removal can help patients regenerate bone and recover function better after surgery.
- Trial name
- NCT07320417
- Testing
- chneiderian Membrane-Preserving
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Wenzhao Guan
Colorectal Cancer (CRC), Early Onset Colorectal Cancer
Trends and Short-term Outcomes of Surgically Resected Early-onset Colorectal Cancer in Switzerland Between 2003 and 2022
The incidence of early-onset colorectal cancer (EOCRC; patients younger than 50 years) has increased worldwide over recent decades. This study aimed to provide nationwide evidence on surgically treated EOCRC in Switzerland.
- Trial name
- NCT07763314
- Testing
- Early-onset colorectal cancer resection, Late-onset colorectal cancer resection
- Where
- Switzerland
- Volunteers
- 73,771 people
- Sponsor
- Cantonal Hospital of St. Gallen
Surgery
Renal Cell Carcinoma Metastases to Pancreas
Patients' outcome was studied after surgery for renal cell carcinoma. The primary outcome was overall survival and desease free survival. Secondary outcame was complications to surgery.
- Trial name
- NCT05882747
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Adenomatous Polyps
Complete Histologic Resection of Adenomatous Polyps?
Colorectal cancer is the second most common cause of cancer death in the US. Colonoscopy is considered the best test colorectal cancer screening.
- Trial name
- CARE (NCT01224444)
- Testing
- standard polypectomy snare
- Where
- 2 sites in United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- White River Junction Veterans Affairs Medical Center
Endoscopic Resection, Gastrointestinal Neoplasms
Efficacy and Safety of Endoscopic Resection
An observational, prospective, multicentre and international study. This will be a non-interventional study to evaluate the efficacy and safety of endoscopic resection of gastrointestinal lesions and to determine what are the…
- Trial name
- NCT03050333
- Where
- Spain
- Volunteers
- 3,000 people
- Sponsor
- EDUARDO ALBENIZ
Non Small Cell Lung Cancer, Lung Cancer
Phase II Lung Metcore - Preoperative Metformin for Lung Cancer
This is a phase II single centre open label single arm pre-operative window of metformin treatment in stage I-IIIa Non small cell lung cancer.
- Trial name
- Metcore (NCT03086733)
- Testing
- Metformin
- Where
- 2 sites in Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
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