Clinical trials: Surgical Resection
Breast Cancer
Surgery With or Without Lymph Node Removal in Treating Older Women With Stage I or Stage IIA Breast Cancer
RATIONALE: Removing axillary lymph nodes may be effective in stopping the spread of breast cancer cells. It is not yet known if surgery to remove breast cancer is more effective with or without lymph node removal.
- Trial name
- 10-93 (NCT00002528)
- Testing
- tamoxifen citrate, conventional surgery, radiation therapy
- Where
- 21 sites in Australia, Hungary and 7 more
- Volunteers
- 473 people
- Sponsor
- ETOP IBCSG Partners Foundation
Liver Metastasis Colon Cancer
Simultaneous Portal and Hepatic Vein Versus Portal Vein Embolizations for Hypertrophy of the Future Liver Remnant
The hypothesis is that liver venous deprivation (LVD) could strongly improve hypertrophy of the future remnant liver (FRL) at 3 weeks, as compared to portal vein embolization (PVE) in patient with liver metastases from…
- Trial name
- HYPER-LIV01 (NCT03841305)
- Testing
- Liver preparation before major hepatectomy
- Where
- 12 sites in France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Montpellier
Ampullary Adenoma
Endoscopic Resection of Papillary Adenomas; a Novel Treatment Algorithm to Prevent Recurrence - a Pilot-study
Recurrence after endoscopic papillectomy is described in up to 33% of the cases (range 12-33%). This leads to re-interventions, a cumulative risk of adverse events, and the need for long-term follow-up.
- Trial name
- ERASE (NCT06216730)
- Testing
- Endoscopic papillectomy
- Volunteers
- 20 people
- Sponsor
- Asian Institute of Gastroenterology, India
Potentially Resection, Hepatocellular Carcinoma
TACE-HAIC vs. HAIC for Potentially Resectable HCC
Hepatocellular carcinoma (HCC) is one of the most commonly malignant tumors around the world. Hepatic resection or liver transplantation is the radical method to cure the disease.
- Trial name
- NCT03591705
- Testing
- TACE-HAIC, HAIC
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Sun Yat-sen University
Gastric Cancer
Effects of Early Oral Feeding After Resection of Gastric Cancer
The aim of this study is to determine whether early oral feeding after curative resection for gastric cancer would be tolerable and give an effect on the recovery.
- Trial name
- NCT00606619
- Testing
- Conventional feeding, Early oral feeding
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- The Catholic University of Korea
Cesarean Section, Surgical Wound Infection
Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m²
Cesarean delivery is one of the most common surgical procedures in obstetric care. Women with obesity (body mass index [BMI] of 30 kg/m² or higher) are at increased risk for postoperative wound complications, including surgical…
- Conditions
- Cesarean Section, Surgical Wound Infection, Wound Healing, Obesity
- Trial name
- NCT07846930
- Volunteers
- 726 people
- Sponsor
- Assiut University
Rectum Cancer
Reconstruction of the Pelvic Floor and Perineal Wound After Rectal ELAPE
A multicenter, cohort, randomized, controlled study is being conducted since the 1of September, 2023 whereby the immediate and long-term results of pelvic floor and perineal wound plastic surgery after extralevatory…
- Trial name
- NCT06066931
- Testing
- Plastic surgery of the pelvic floor and perineal wound with counter-displaced skin-subcutaneous fascial flaps after extralevatory abdominal-perineal extirpation of the rectum, Plastic surgery of the pelvic floor and perineal wound with local tissues, Plastic surgery of the pelvic floor and perineal wound with mesh endoprosthesis
- Volunteers
- 150 people
- Sponsor
- Kuban State Medical University
Surgery, Pain, Postoperative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll.
- Trial name
- CARES (NCT05722002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 8 sites in United States, Canada
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Rectal Cancer, LARS - Low Anterior Resection Syndrome
Personalized Care Pathways for Bowel Symptoms in Rectal Cancer Patients_contributing Factors (Treatable)
Colorectal cancer is the 2nd and 3rd most common cancer in respectively women and men, of which about 40% is located in the rectum.
- Conditions
- Rectal Cancer, LARS - Low Anterior Resection Syndrome, Active Surveillance
- Trial name
- Treatable (NCT06914245)
- Testing
- Electronic bowel diary, Faecal Incontinence Quality of Life questionnaire (FIQL), EuroQoL 5 dimensions, 5 levels (EQ-5D-5L)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- KU Leuven
Non-muscle Invasive Bladder Cancer
Study of CG0070 After Transurethral Resection in Patients With IR NMIBC
Investigators will evaluate the safety of CG0070 for the treatment of patients with Intermediate-Risk Non-Muscle Invasive Bladder Cancer (IR NMIBC).
- Trial name
- NCT06253845
- Testing
- CG0070
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Pulmonary Aspergillosis, Surgery-Complications
Uniportal VATS Resection for Pulmonary Aspergilloma : Evaluation of Prognostic Factors in a Single Center Experience
The objective of this study was to report our experience with U-VATS resection and to evaluate our surgical outcomes with an analysis of postoperative complications.
- Conditions
- Pulmonary Aspergillosis, Surgery-Complications, Thoracic Diseases
- Trial name
- NCT06564727
- Testing
- Uniportal VATS approach, VATS approach
- Where
- Morocco
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hassan II University
Predictive Value of ICG Clearance Measurement During Selective Hepatic Vascular Trial Clamping on Remnant Liver Function After Anatomic Liver Resection
Predictive Value of Intraoperative Indocyanine Green Clearance Test After Partially Blood Flow Blocking in Postoperative Liver Reserve
Predictive value of intraoperative indocyanine green clearance measurement during selective hepatic vascular trial clamping on remnant liver function after anatomic liver resection.
- Trial name
- NCT03654183
- Testing
- Indocynine green clearance test
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Fudan University
Superficial Colorectal Tumors
Predictive Factors for Failure or Success of Endoscopic Treatment of Superficial Colorectal Tumors
To evaluate the long-term complete remission rate (> 12 months) after endoscopic treatment of early neoplastic colorectal lesions.
- Trial name
- REC (NCT03470883)
- Testing
- Evaluation of the long-term complete remission rate (> 12 months)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Institut Paoli-Calmettes
Esophageal Cancer, Gastrooesophageal Cancer
Esophageal Stump Washout
Intraluminally shed viable tumor cells might contribute to local recurrence in cancer of the esophagus and the cardia. The aim of the the study was to establish a method of mechanical lavage of the remaining part of the esophagus…
- Trial name
- NCT01980394
- Testing
- Esophageal Stump Washout
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Kantonsspital Liestal
Newly-diagnosed Glioblastoma, Temporal Lobe
Anterior Temporal Lobectomy in Temporal Glioblastoma
The ATLAS/NOA-29 trial is a prospective, multicenter, phase III randomized controlled study evaluating whether anterior temporal lobectomy (ATL), a standardized resection technique adapted from epilepsy surgery, improves clinical…
- Trial name
- ATLAS/NOA-29 (NCT07021339)
- Testing
- Anterior temporal lobectomy (ATL), Gross Total Resection (GTR)
- Where
- Germany
- Volunteers
- 178 people
- Sponsor
- University Hospital, Bonn
Focal Epilepsy, Intraoperative Monitoring
High-density Flexible μECoG for Epilepsy Surgery - A Single-Arm ECT
What's the clinical value of high-density flexible microelectrocorticography (μECoG) for guiding the resection of epileptogenic zone (EZ) in epilepsy surgery?
- Trial name
- Epi-PRECISE (NCT07656857)
- Testing
- Using High-density Flexible microElectrocorticography for intraoperative monitoring
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Beijing Tiantan Hospital
Hemostatic Techniques, Nephrectomy
Safety and Hemostatic Efficacy of Fibrin Fleece in Partial Nephrectomy
This is a prospective, randomized, single blind, standard care- controlled study, which will include a total of 30 patients divided into two treatment arms: First are: patents who will be treated in accordance with standard of…
- Trial name
- Fleece (NCT00598130)
- Testing
- Fleece
- Where
- 4 sites in Israel
- Volunteers
- 30 people
- Sponsor
- OMRIX Biopharmaceuticals
Rectal Cancer
PReventive cOlostomy vs Ileostomy in Low anTErior reCTal Resection
The type of preventive intestinal stoma (colostomy/ileostomy) after low anterior rectal resection rectum is still a debate. This study purpose is to demonstrate that preventive loop ileostomy is characterized by a higher…
- Trial name
- PROTECT (NCT04357171)
- Testing
- Low anterior resection with protective loop ileostomy, Low anterior resection with protective loop transverse colostomy
- Volunteers
- 202 people
- Sponsor
- Russian Society of Colorectal Surgeons
Lung Injury, Lung Inflammation
The Effects of Different Ventilation Modes on Patients With Pulmonary Lobe Resection
The objective of this study was to discuss the effects of different ventilation modes on patients with plasma inflammatory factor and respiratory function in patients with pulmonary removal.
- Trial name
- NCT06514729
- Testing
- Adopting different ventilation modes during the operation
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Mao Enting
Colorectal Cancer
Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as capecitabine, oxaliplatin, fluorouracil, and leucovorin, work in different ways to stop the growth of tumor cells…
- Trial name
- NCT00541112
- Testing
- cetuximab, capecitabine, fluorouracil
- Where
- 10 sites in France
- Volunteers
- 19 people
- Sponsor
- UNICANCER
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