Clinical trials: Surgical Risk Prediction
Hip Fracture, MACE
AI-Based Risk Factor Analysis and Prediction Model of MACE in Elderly Hip Fracture Patients Postoperatively
This is a multicenter ambispective observational cohort study led by Beijing Anzhen Hospital, Capital Medical University, with China-Japan Friendship Hospital serving as the external validation center.
- Conditions
- Hip Fracture, MACE, Elderly, Perioperative Complications
- Trial name
- NCT07709377
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Beijing Anzhen Hospital
Hospital Acquired Pneumonia
Pneumonia After Cardiovascular Surgery With Artificial Intelligence
This multicenter, prospective, observational study aims to address two primary objectives. The first objective is to demonstrate that hospital-acquired pneumonia (nosocomial pneumonia) following cardiac surgery can be predicted…
- Trial name
- NCT07745491
- Testing
- Not applicable- observational study
- Where
- Russia
- Volunteers
- 700 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Moderate to High-risk Noncardiac Surgery
Hypotension Prediction Index (HPI) SMART-BP Trial
A multicenter, randomized comparison of intraoperative hemodynamic management with or without a protocolized strategy utilizing Hypotension Prediction Index (HPI) software guidance during moderate-to-high-risk noncardiac surgery.
- Trial name
- NCT05105477
- Testing
- AcumenTM HPI Software Feature, Non-protocolized Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 407 people
- Sponsor
- Edwards Lifesciences
Intraoperative Hypotension
Hypotension Prediction Index for Blood Pressure Management
Design: Single-center randomized comparison of invasive arterial pressure monitoring vs. arterial pressure monitoring combined with Acumen Hypotension Prediction Index (HPI) software guidance on intraoperative hypotension…
- Trial name
- HPI (NCT03610165)
- Testing
- Acumen HPI-enabled EV1000 screen, Control
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- The Cleveland Clinic
Pituitary Adenoma
Pre-operative Surgical Difficulty Stratification Using Predicted Tumor Perfusion and Consistency
Pituitary adenomas (PAs) are among the most prevalent lesions of the sella turcica, accounting for 10%-25% of all intracranial neoplasms. Pituitary macroadenomas (PMAs) are defined with a maximum diameter of over 1 cm.
- Trial name
- NCT06664190
- Testing
- Advanced sequences, such as arterial spin labeling (ASL) and diffusion-weighted imaging (DWI)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Huashan Hospital
CSA-AKI, Acute Kidney Injury
Discovery and Validation of Biomarkers for CSA-AKI Risk Prediction
This study aims to discover and validate new biomarkers for predicting CSA-AKI before cardiovascular surgery. Nested case-control studies embedded in prospective cohorts.
- Conditions
- CSA-AKI, Acute Kidney Injury, Cardiovascular Surgery, Biomarkers
- Trial name
- NCT07811570
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China National Center for Cardiovascular Diseases
Acute Postoperative Pain, Chronic Post Operative Pain
Clinical Prediction of Post-surgical Pain
This study aims to externally validate two clinical prediction models for moderate-to-severe acute post-surgical pain and chronic post-surgical pain.
- Trial name
- NCT06661642
- Where
- 2 sites in Denmark
- Volunteers
- 748 people
- Sponsor
- Aarhus University Hospital
Heart Block, Risk Factor
New-onset Heart Blocks After Noncardiac Surgery: a Retrospective Study of More Than 280,000 Patients
This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model.
- Trial name
- NCT06119009
- Testing
- non interventions
- Volunteers
- 281,497 people
- Sponsor
- Chinese PLA General Hospital
Lung Cancer (Diagnosis), Deep Vein Thrombosis (DVT)
Study of Risk Factors and Prediction of Blood Clots After Lung Cancer Surgery
The goal of this observational study is to learn about the risk factors and prediction of postoperative venous thromboembolism (VTE) in patients undergoing lung cancer surgery.
- Conditions
- Lung Cancer (Diagnosis), Deep Vein Thrombosis (DVT), Venous Thromboembolism (VTE)
- Trial name
- NCT07439991
- Testing
- Prospective Perioperative Data Collection
- Where
- China
- Volunteers
- 900 people
- Sponsor
- The First Hospital of Jilin University
Postoperative Nausea and Vomiting
A Machine Learning Prediction Model for Delayed CIPONV
Postoperative nausea and vomiting (PONV) can lead to serious postoperative complications, but most symptoms are mild. Clinically important PONV (CIPONV) refers to PONV symptoms that have a significant impact on the patient's…
- Trial name
- NCT06443697
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,154 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
DVT - Deep Vein Thrombosis, VTE (Venous Thromboembolism)
Padua Prediction Score for VTE Risk in Thoracic Surgery Patients
The goal of this observational study is to assess the predictive accuracy of the Padua Prediction Score (PPS) for venous thromboembolism (VTE) risk in thoracic surgery patients.
- Trial name
- DVT (NCT06732726)
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- Al-Nahrain University
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Prolonged Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after prolonged surgery.
- Trial name
- NCT04926025
- Where
- 5 sites in China
- Volunteers
- 500,000 people
- Sponsor
- Huazhong University of Science and Technology
Observation, Postoperative
Proteomics and Physiological Parameters Predicting Complications After Colorectal Cancer Surgery
Study combines physiological data from wearables, continuous glucose montiors and proteomics to better assess risk of complications after colorectal surgery
- Trial name
- ProComp (NCT07494669)
- Testing
- Risk stratification with proteomics and data from wearables and CGMs
- Volunteers
- 210 people
- Sponsor
- Region Skane
Ovarian Cancer
The Exploration of Personalized ctDNA Based MRD in the Clinical Significance of Cervical Cancer
This study plans to enroll 80 patients with locally advanced cervical cancer (stage IB-ⅣA) confirmed by histology or cytology (according to the 2018 FIGO staging standard), who are expected to receive surgical resection or…
- Trial name
- NCT06283875
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Geneplus-Beijing Co. Ltd.
Heart; Dysfunction Postoperative, Cardiac Surgery, Cytokine Release Syndrome
Peri-operative Prediction of Prolonged Stay in the Cardiac Intensive Care Unit for Adult Cardiac Surgery
The purpose of this study is to create a model using intra-operative modified SOFA score and peri-operative clinical factors to predict prolonged stay in the cardiac intensive care unit (CICU) for adult cardiac surgery with…
- Trial name
- NCT01559870
- Where
- 3 sites in Thailand
- Volunteers
- 164 people
- Sponsor
- Thepakorn Sathitkarnmanee
Gastric Cancer (GC)
Development and Validation of the Surgical Assessment and Healthcare (SAH) Index for Gastric Cancer Treatment Evaluation
This study develops the Surgical Assessment and Healthcare (SAH) Index, a new tool to fairly evaluate gastric cancer surgery outcomes.
- Trial name
- SAH (NCT07180966)
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Ruijin Hospital
Cardiovascular Diseases, Elderly Patients
Prediction Model of Cardiac Risk for Dental Extraction in Elderly Patients With Cardiovascular Diseases
This study intends to investigate the relevant risk factors of perioperation complications or mortality in older patients with cardiac diseases undergoing teeth extraction surgery and this study aims to quantify the risk factors…
- Conditions
- Cardiovascular Diseases, Elderly Patients, Tooth Extraction
- Trial name
- NCT03211312
- Where
- China
- Volunteers
- 833 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Cervical Cancer, HPV DNA
Postoperative ctHPV-DNA for Recurrence Prediction and Adjuvant Treatment Decision-Making in Cervical Cancer
This prospective observational study will evaluate whether changes in circulating tumor human papillomavirus DNA (ctHPV-DNA) after radical surgery can help predict the risk of recurrence in patients with HPV-associated cervical…
- Trial name
- NCT07782697
- Where
- China
- Volunteers
- 580 people
- Sponsor
- Anhui Provincial Hospital
Penile Cancer, Recurrent
Prediction of Local Recurrence and Its Impact on Long-term Outcomes After Low-risk Glans-sparing Surgery for Penile Squamous Cell Carcinoma
The treatment paradigm for primary penile squamous cell carcinoma (PSCC) has increasingly favored maximal organ preservation without compromising oncological outcomes.
- Trial name
- NCT06565585
- Testing
- Glans-sparing surgery
- Where
- Belgium
- Volunteers
- 800 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hypothermia, Accidental, Hypothermia; Anesthesia
Constructing a Risk Prediction Model for Intraoperative Hypothermia in Children Under General Anesthesia
Intraoperative hypothermia refers to a core body temperature below 36.0°C during surgery, which is common in surgical patients. Due to the fact that children's body temperature regulation function is not yet fully developed, they…
- Trial name
- NCT06892795
- Where
- China
- Volunteers
- 562 people
- Sponsor
- Harbin Medical University