Clinical trials: Surgical Technique
Preoperative Anxiety Experienced by the Pediatric Patient, Dental Anxiety in Children
Evaluating Operation Calm With Children, Parents, and Clinicians
Operation Calm is a single-arm, mixed-methods feasibility study evaluating a virtual reality (VR) nature-based mindfulness intervention with children and adolescents aged 6-17 years, parents, and clinicians.
- Conditions
- Preoperative Anxiety Experienced by the Pediatric Patient, Dental Anxiety in Children, Procedural Anxiety
- Trial name
- NCT07694934
- Testing
- Operation Calm EEMCF-VR
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- McGill University
Total Knee Replacement, Venous Thromboembolism
Total Knee Arthroplasty And Thromboembolism: A Comparison Between Two Surgical Techniques
In patients undergoing total knee arthroplasty, thromboembolism is a common occurrence, especially following tourniquet deflation.
- Trial name
- NCT00755300
- Testing
- Measurement of total thrombolic load
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, Davis
Endoscopic Sinus Surgery
SPI-guided vs PRD-guided Analgesia During FESS for Intraoperative Blood Loss
The aim of this randomized trial is to assess the efficacy of analgesia , compare the utility of Pupillary Dilatation Reflex (PRD), Surgical Pleth Index (SPI) for monitoring pain perception intraoperatively and their influence on…
- Trial name
- NCT03389763
- Testing
- Remifentanil
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Silesia
Breast Cancer
New Techniques to evAlUate Response to neOadjuvant Treatments in bReast cAncer (AURORA)
The role of neoadjuvant chemotherapy (NAC) in breast cancer is well established. Increasing rates of pathologic complete response (pCR) has increased de-escalation of surgical techniques.
- Trial name
- AURORA (NCT04795349)
- Testing
- Vacuum-assisted breast biopsy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Lumbar Spinal Stenosis, Radiculopathy
Treatment of Lumbar Spinal Stenosis; Comparison of Two Different Surgical Methods; Mini-invasive Decompression to X-stop
The purpose of this study is to compare two surgery methods on lumbar spinal stenosis: minimal invasive decompression and X-stop.
- Trial name
- LSSS (NCT00546949)
- Testing
- Minimal invasive decompression, Interspinous Process Decompression (IPD)
- Where
- Norway
- Volunteers
- 96 people
- Sponsor
- Norwegian University of Science and Technology
Primary Haemostasis Disorder in Cardiac Surgery Patients
Relation Between the Value of Platelet Clot Stiffness (PCS) Obtained by Sonorheometric Method of Delocalized Hemostasis (QUANTRA®), and the Presence of a Disorder of Primary Hemostasis, in Cardiac Surgery Patients. PLAQUA-Study
The goal of this study is to determine whether the Platelet Clot Stiffness (PCS) measured by QUANTRA® is predictive of an abnormality in primary haemostasis intraoperatively in cardiac surgery performed under extracorporeal…
- Trial name
- PLAQUA (NCT06585930)
- Testing
- Blood sample
- Where
- Reunion
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Postoperative Care
Air Stacking Technique Efficacy on Peak of Expiratory Flow and Cough Peak Flow in Non-cardiac Thoracic Surgery
After thoracic surgical intervention, patients often feel intense pain with respiratory movements reduction making coughing less effective.
- Trial name
- NCT06341244
- Testing
- Air Stacking Technique
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Cidade de Sao Paulo
Spine Erector, Cardiac Surgery
Comparison Erect Spine in Cardiac Surgery
Open cardiac surgeries are characterized by the increased use of opioids and longer extubation times, being post-sternotomy pain one of the causes of greater patient discomfort, plexus blockages have been used more frequently…
- Conditions
- Spine Erector, Cardiac Surgery, Acute Pain, Chronic Pain
- Trial name
- COESPINE (NCT04313959)
- Testing
- Ropivacaine 0.2% Injectable Solution, Ropivacaine 0.2% + Dexamethasone
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Instituto do Coracao
Severe Obesity, GERD
Comparison of the Sleeve Gastrectomy Technique With a Nissen Fundoplication Added to the Conventional Sleeve Gastrectomy Technique in Morbidly Obese Patients
The purpose of this study is to evaluate the impact of the procedure (sleeve gastrectomy technique with a Nissen fundoplication (N-Sleeve) vs conventional sleeve gastrectomy technique
- Conditions
- Severe Obesity, GERD, Bariatric Surgery Candidate, Morbid Obesity
- Trial name
- N'SLEEVE (NCT04626232)
- Testing
- N-SLEEVE technique, SLEEVE
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Montpellier
Colorectal Cancer
Interrupted 'Figure-of-X' Versus Continuous Suturing Technique for Abdominal Wall Closure in Colorectal Laparotomies
This prospective randomized comparative study aims to evaluate whether interrupted figure-of-X fascial closure reduces the incidence of burst abdomen compared with continuous suturing in patients undergoing open colorectal…
- Trial name
- X-CLOSURE (NCT07585344)
- Testing
- Interrupted 'Figure-of-X' Suturing Technique, CONTINUOUS AMSS CLOSURE
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Islamabad Medical and Dental College
Periodontal Diseases
Evaluation of Enamel Matrix Derivative as an Adjunct to Minimally Invasive Non-surgical Treatment of Intrabony Defects.
Aim: The aim of this prospective, randomized, parallel arm, blind, controlled clinical trial is to compare the clinical and radiographic outcomes following regenerative treatment of intrabony periodontal defects using a Minimally…
- Trial name
- NCT03622255
- Testing
- MINST, MINST with EMD
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Patient Care Team, Coronary Artery Disease
Developing an Intervention to Improve the Non-Technical Skills of the Cardiac Surgical Teams
Teams of several medical professionals conduct high-risk cardiac surgical procedures. These professionals work in complex, stressful operating room environments requiring effective communication and teamwork skills.
- Conditions
- Patient Care Team, Coronary Artery Disease, Coronary Artery Bypass, Surgery
- Trial name
- NCT06257511
- Testing
- Simulation-Based Mastery Learning of the Non-technical skills
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Hip Replacement
Patient Outcomes Using HIP7 Software as Compared to Conventional THA
The study is designed to demonstrate how Hip7 software can lead to improved patient outcomes compared to conventional procedures with standard instrumentation for total hip arthroplasties (THA) surgery.
- Trial name
- NCT04989998
- Testing
- Hip7 Software on Kick/ CORI platforms, Conventional surgical procedures
- Sponsor
- Smith & Nephew Orthopaedics AG
Exercise Movement Techniques, Cardiac Surgery
Cycle Ergometer Exercise in Phase I of Cardiac Rehabilitation After Cardiac Surgery
The prevalence of heart diseases has increased significantly in recent years and it is a health public problem due to an increased risk of death by several reasons.
- Trial name
- NCT02437552
- Testing
- ergometer cycle exercise, routine physiotherapy
- Where
- Brazil
- Sponsor
- University of Sao Paulo
Abdominal Surgery
Effects of ACBT and Blow Bottle Technique in Patients With Abdominal Surgeries Under General Anesthesia
A postoperative pulmonary complication (PPC) is the most common serious complication after Abdominal surgery under GA which lead to longer hospital stays and have deleterious outcomes on lung volumes, mucociliary clearance…
- Trial name
- NCT06454305
- Testing
- Active cycle of breathing technique, Blow Bottle Technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Cardiac Surgery in Adult Patient, Cardiac Surgery
Direct vs. Seldinger Technique for Ultrasound-Guided Difficult Radial Access in Cardiac Surgery
Radial artery cannulation is a routine procedure for invasive hemodynamic monitoring for patients undergoing cardiovascular surgery patients.
- Conditions
- Cardiac Surgery in Adult Patient, Cardiac Surgery, Radial Artery Cannulation, Arterial Cannulation
- Trial name
- NCT07400627
- Testing
- Ultrasound-Guided Direct Cannulation Technique, Ultrasound-Guided Seldinger Cannulation Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people
- Sponsor
- Diskapi Teaching and Research Hospital
Dental Implant, Tooth Loss
Flap Vs Flapless Technique for Delayed Implant Placement in the Maxillary Esthetic Zone
This randomized comparative clinical trial aims to evaluate the clinical, radiographic, and esthetic outcomes of flap versus flapless techniques for delayed dental implant placement in the maxillary esthetic zone.
- Conditions
- Dental Implant, Tooth Loss, Partial Edentulism, Maxillary Tooth Loss
- Trial name
- NCT07654452
- Testing
- Flap Implant Placement, Flapless Implant Placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Peritoneal Carcinomatosis, Appendiceal Neoplasms
Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC)
The goal of this prospective phase II unicentric Canadian clinical trial is to clarify the feasibility of modified early post-operative intraperitoneal chemotherapy (mEPIC) following cytoreductive surgery (CRS) and hyperthermic…
- Conditions
- Peritoneal Carcinomatosis, Appendiceal Neoplasms, Colorectal Cancer Metastatic
- Trial name
- NCT05913674
- Testing
- Modified early post-operative intraperitoneal chemotherapy (mEPIC)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Intrabony Periodontal Defect
Novel Silk Fibroin Nanofiber Membrane Using Minimally Invasive Surgery in Treatment of Periodontal Intrabony Defects: A Randomized Clinical Trial
Clinically and radiographically by cone beam CT evaluate the regenerative potentials of silk fibroin (SF) nanofiber membrane, using minimally invasive surgery, for the regenerative treatment of intrabony periodontal defects.
- Trial name
- NCT06371027
- Testing
- Minimally Invasive Surgery Technique (MIST) + Novel Silk Fibroin (SF) nanofiber membrane, Minimally Invasive Surgery Technique (MIST) + collagen membrane, Minimally Invasive Surgery Technique (MIST)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October 6 University
Cholecystolithiasis
Madany Closure: A Novel Technique for Fascial Closure in Laparoscopic Surgery
this study aims to evaluate the effectiveness of the use of a basic laparoscopic instrument (Only needle holder) with a new technique for port site closure
- Trial name
- NCT06035302
- Testing
- Madany Closure, Standard closure
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- ClinAmygate