Clinical trials: Surgical Wound, Healed
Surgical Site Infection (SSI), Mediastinitis
Use of Platelet-Rich Plasma to Reduce Sternal Wound Complications After CABG With Median Sternotomy
The goal of this clinical trial is to learn whether applying autologous platelet-rich plasma (PRP) to the sternal wound during heart surgery improves wound healing and reduces complications after surgery.
- Conditions
- Surgical Site Infection (SSI), Mediastinitis, Delayed Wound Healing
- Trial name
- NCT07352020
- Testing
- Autologous Platelet-Rich Plasma (PRP) Application, Standard Sternal Wound Closure
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Wound of Skin, Wound Heal
Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds
The use of topical beta-blockers, such as 0.25% timolol, in promoting wound healing is currently emerging in the academic literature.
- Conditions
- Wound of Skin, Wound Heal, Wound Open, Surgical Wound
- Trial name
- NCT03452072
- Testing
- 0.25% Timolol gel with paraffin gauze dressings, Vaseline dressing
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Impacted Mandibular Third Molar, Postoperative Wound Healing
Soft Tissue Healing and Bacterial Load With Triclosan-Coated Sutures After Impacted Mandibular Third Molar Surgery
The goal of this clinical trial is to learn if triclosan-coated absorbable stitches (polyglactin 910 sutures coated with triclosan, an antibacterial agent) help soft tissue heal better and have fewer bacteria stuck to the…
- Trial name
- NCT07386366
- Testing
- Triclosan-coated Polyglactin 910 suture, Non-coated polyglactin 910 suture
- Where
- Vietnam
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Non-healing Wounds
Effect of Natrox Oxygen Wound Therapy on Non-healing Wounds and Implication of Remote Monitoring and Telehealth for Management in the Home.
Single center pilot study examining the effect of Natrox topical oxygen therapy on chronic wounds along with the introduction of remote monitoring and telehealth for home care management.
- Trial name
- NCT04746573
- Testing
- Natrox Topical Oxygen Therapy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Inotec AMD Limited
Cardiac Surgery, Infection, Soft Tissue
Exploring if Patients Can Safely and Easily Swab Their Own Surgical Wounds at Home
The goal of this observational feasibility study is to learn if patients can safely, acceptably, and effectively collect their own wound swabs at home to detect clinically significant organisms in adults aged 18 and over who have…
- Conditions
- Cardiac Surgery, Infection, Soft Tissue, Wound Healing, Swabs
- Trial name
- TREASURE (NCT07200401)
- Testing
- Self-swabbing of surgical wound
- Where
- 2 sites in United Kingdom
- Volunteers
- 43 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Osteoarthritis, Hip, Joint Deformities, Acquired
Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty
The purpose of this study is to establish whether or not there is a clinical advantage to the use of Aquamantys® System from Medtronic Advanced Energy (formerly Salient Surgical Technologies) in patients undergoing primary total…
- Conditions
- Osteoarthritis, Hip, Joint Deformities, Acquired, Hip Dislocation, Congenital, Osteonecrosis
- Trial name
- Aquamantys (NCT01583465)
- Testing
- Aquamantys, standard electrocautery (Bovie)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Joint Implant Surgeons, Inc.
Periodontal Inflammation, Crown Lengthening
Effect of Emdogain® on Soft Tissue Wound Healing
The goal of this randomized, controlled, single-center study is to compare the effects of Emdogain®, a regenerative biomaterial, on post-operative pain, wound healing and inflammation of treated sites after surgical crown…
- Trial name
- NCT06179277
- Testing
- PrefGel® + Emdogain®, PrefGel®
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amir Azarpazhooh
Diabetic Foot
Sealed Therapeutic Shoe as Treatment of Diabetic Foot Ulcers
Total contact casts (TCCs) are effective treatment of plantar diabetic foot ulcers because they effectively offload the ulcer and are non-removable, resulting in high adherence to using the device.
- Trial name
- NCT04085926
- Testing
- Sealed therapeutic shoe, Total contact cast
- Where
- 3 sites in Sweden
- Volunteers
- 4 people
- Sponsor
- Region Örebro County
Pain, Postoperative, Healing Surgical Wounds
Comparative Evaluation of Various Patient Centered Outcomes Following Gingival Depigmentation Using Diode LASER in Different Modes: A Randomized Clinical Trial
Purpose of this study is to clinically evaluate and compare various patient centered outcomes using diode LASER in Continuous mode (CW) and Pulsed Mode (PM) using 300µm and 400µm fiber for depigmentation procedure.
- Conditions
- Pain, Postoperative, Healing Surgical Wounds, Analgesia, Temperature Change, Body
- Trial name
- LASER (NCT04217434)
- Testing
- 400 µm fibre length will be used in continuous contact mode, 400 µm fibre length will be used in pulsed contact mode, 300 µm fibre length will be used in continuous mode
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Postoperative Wound Healing in Anal Fistula Surgery
Tongyangxiao Lotion for Postoperative Wound Healing After Anal Fistula Surgery
This study tests whether a traditional Chinese herbal bath called Tongyangxiao (TYX) lotion helps surgical wounds heal faster in patients who have had anal fistula surgery.
- Trial name
- NCT07562672
- Testing
- Tongyangxiao (TYX) group, Potassium permanganate (PP) group
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Yongkang An
Thyroid Diseases, Wound Healing
Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control
The goal of this clinical trial is to evaluate the therapeutic efficacy and safety of non-thermal plasma (NTP) as an adjuvant treatment for surgical bed decontamination and accelerated tissue repair in patients undergoing total…
- Conditions
- Thyroid Diseases, Wound Healing, Thyroidectomy, Surgical Wound Infection
- Trial name
- NCT07382973
- Testing
- Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Surgical Wound
Effect of Replacing Buried Sutures With Tissue Adhesive on Aesthetic Outcome of Surgical Wounds.
Surgery wounds are typically closed with combination of absorbable stitches placed under the skin and non-absorbable stitched placed at the skin surface.
- Trial name
- NCT03425370
- Testing
- Closure of surgical wounds using buried sutures or tissue adhesive on aesthetic outcome.
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Macromastia
Study of Prineo (Dermabond Protape) Versus Sutures in Breast Procedures
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 patients with full thickness surgical incisions associated with bi-lateral breast procedures.
- Trial name
- NCT00558246
- Testing
- Dermabond Protape (Prineo), Suture
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 79 people
- Sponsor
- Ethicon, Inc.
Impaired Wound Healing, Factor XIII Deficiency
Wound Healing Abnormalities in Major Abdominal Surgery
This clinical observational study investigates the incidence of wound healing abnormalities in patients undergoing major abdominal surgery.
- Trial name
- INWOUND (NCT00735579)
- Where
- Germany
- Volunteers
- 260 people
- Sponsor
- Klinikum St. Georg gGmbH
Tourniquets, Knee Arthroplasty, Total
Tourniquet Pressure in Primary Total Knee Arthroplasty
This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and…
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Trial name
- NCT02830087
- Testing
- Tourniquet Cuff Pressure
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Arthroplasty, Knee Replacement, Wound Healing
Zip® Surgical Skin Closure Device vs. Staples for Skin Closure in Subjects Having Undergone Bilateral Knee Arthroplasty
Study designed to compare the Zip Surgical Skin Closure device vs. conventional staples for wound closure following bi lateral knee replacement surgery.
- Trial name
- NCT02460172
- Testing
- Zip Surgical Skin Closure, Steel Staples
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ZipLine Medical Inc.
Dermatochalasis, Blepharoplasty
Electrocautery Versus Scalpel Incision in Upper Eyelid Blepharoplasty
This prospective randomized contralateral comparative study aims to compare electrocautery and scalpel incision techniques in upper eyelid blepharoplasty.
- Trial name
- ELECT-BLEPH (NCT07749846)
- Testing
- Electrocautery incision, Scalpel incision
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Beyoglu Eye Research and Education Hospital
Chronic Rhinosinusitis, Nasal Polyps
Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trial
This is a randomized, double blind, placebo controlled, parallel group, study in patients with chronic rhinosinusitis with or without nasal polyps.
- Trial name
- DOXYPOSTOP (NCT01198912)
- Testing
- doxycycline 100 mg
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 33 people
- Sponsor
- University Hospital, Ghent
Hypertrophic
A Study of a Novel Silicone Dressing to Minimize Scar Formation
Neodyne has developed an investigational dressing for post-operative incision care. Neodyne is conducting this research to study whether the investigational dressing, called the Neodyne Dressing, can minimize scar formation in a…
- Trial name
- REFINE (NCT01399099)
- Testing
- embrace device
- Where
- 13 sites in United States
- Volunteers
- 67 people
- Sponsor
- Neodyne Biosciences, Inc.
Ankle Fractures
Factors Influencing the Risk of Surgical Site Infections and Wound Complications in Operatively Treated Ankle Fractures in the Elderly
This study is to analyse risk factors for wound complications or surgical site infections and to analyse whether risk factors for wound complications or surgical site infections are also factors for other complications.
- Trial name
- NCT04379791
- Testing
- Data collection from routine medical records
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Basel, Switzerland