Clinical trials: Surgical Wound Healing
Tendon Adhesion
Ultrasound-Guided Multiple Saline Injections for Prevention of Tendon Adhesion: A Randomized Controlled Trial
This prospective randomized controlled trial aims to evaluate the efficacy and safety of ultrasound-guided repeated normal saline injections for the prevention and treatment of tendon adhesion following flexor tendon repair.
- Trial name
- NCT07184658
- Testing
- Ultrasound-guided peritendinous saline injection
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Kai Wang
Scar
Disposable Noninvasive Skin Closure for Promoting Postoperative Wound Healing and Preventing Surgical Skin Scarring
The purpose of this study is to evaluate the efficacy and safety of a disposable noninvasive skin closure device in promoting postoperative wound healing and reducing surgical scar formation.
- Trial name
- NCT07849010
- Testing
- Disposable Noninvasive Skin Closure Device (Shanghai Zhizhong Medical Technology Co., Ltd. Catalog No.: 240430PFF)
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Peking University Third Hospital
Umbilical Hernia, Epigastric Hernia
Risk Factors for Poor Outcome After Epigastric and Umbilical Hernia Repair
Umbilical and epigastric hernia repairs are common and performed by numerous surgical techniques. Considering that the hernia repairs in general are relatively small and simple procedures there are disproportionate poor results.
- Trial name
- NCT01665859
- Where
- Denmark
- Volunteers
- 6,783 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Inguinal Hernia
ProGrip Mesh Repair vs Lichtenstein Operation
The purpose of this trial is to compare clinical outcomes and to analyze cost-effectiveness following self-gripping, sutureless Parietex ProGrip Mesh to traditional Lichtenstein Operation with lightweight polypropylene mesh.
- Trial name
- NCT02748629
- Testing
- Covidien Parietex ProGrip Self-Fixating Mesh, Lightweight Polypropylene Mesh (<38g/m2 after absorption)
- Where
- Poland
- Volunteers
- 143 people
- Sponsor
- Regional Health Center in Kartuzy, Poland
External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block
External Oblique Intercostal Fascial Plane Block Versus Rectus Sheath Block for Postoperative Analgesia
This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty.
- Conditions
- External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block, Pain
- Trial name
- NCT07601945
- Testing
- External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Helwan University
Tendon Injuries
Adaprev in Digital Flexor Tendon Repair
This study is being undertaken to verify the safety and performance of Adaprev™, a Class III medical device, when administered as a short term implant into the tendon sheath at the time of surgery, on the post-operative function…
- Trial name
- NCT01014494
- Testing
- Adaprev
- Where
- 9 sites in United Kingdom
- Volunteers
- 44 people
- Sponsor
- Renovo
Pelvic Organ Prolapse
Composite Outcomes of Mesh vs Suture Techniques for Prolapse Repair: A Randomized Controlled Multicentre Trial
This is a Canadian, multi-centre, double-blind randomized controlled trial of an innovative vaginal surgery technique for correction of pelvic organ prolapse (POP) in women.
- Trial name
- COMET (NCT02965313)
- Testing
- SSLS Procedure, BSSVF-M Procedure
- Where
- Canada
- Volunteers
- 358 people
- Sponsor
- University of British Columbia
Aortic Aneurysm, Aortic Aneurysm Abdominal
Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery
This clinical study aims to evaluate the effectiveness and safety of using NE'X Glue R-eco to seal suture lines. The adhesive will be applied to reduce the risk of suture line bleeding in cardiac or vascular repair surgeries, a…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm Abdominal, Valve Stenoses, Aortic, Valve Regurgitation, Mitral
- Trial name
- CLOSURE (NCT06918496)
- Testing
- Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair.
- Where
- 2 sites in Belgium, Poland
- Volunteers
- 60 people
- Sponsor
- Grena Biomed Limited
Pain, Postoperative
Defining the Best Approach to Block the Pain After Knee Surgery
The study aims to compare standard techniques used to control pain after knee surgery. The investigators hypothesize that the fascia iliaca block is faster, safer and as good as or better than the femoral block, with or without a…
- Trial name
- NCT00294073
- Testing
- Fascia Iliaca Block, Femoral Block (with stimulating catheter), Femoral Block (without stimulating catheter)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Inguinal Hernia
Long-term Follow-up of Lichtenstein's Operation Versus Mesh Plug Repair
Long-term follow-up of a randomized clinical trial of Lichtenstein's operation versus mesh plug for inguinal hernia repair based on the following published study "Randomized clinical trial of Lichtenstein's operation versus mesh…
- Trial name
- NCT01637818
- Testing
- Lichtenstein's operation, Mesh Plug Repair, Opiate
- Where
- Switzerland
- Volunteers
- 594 people
- Sponsor
- University Hospital, Basel, Switzerland
Surgical Scar Tissue of Cesarean Section or Vaginal Tear or Episiotomy
Low Level Laser Therapy for Better Wound Healing
Prospective randomized double blind study. Intervention 1: Low-level laser therapy ca. 72 Joules vs. Intervention 2: No Low-level laser therapy. Outcome: Pain score \& would healing at discharge, 1 months \& 3 months
- Trial name
- NCT06220786
- Testing
- Low-level laser therapy, "Fake" low-level laser therapy
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Elisabethen Krankenhaus Frankfurt GmbH
Anterior Cruciate Ligament Tear
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) that promotes reattachment and healing of the ACL…
- Trial name
- BEAR-MOON (NCT03776162)
- Testing
- ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Open Spina Bifida, Myelomeningocele
Fetoscopic Open Spina Bifida Repair Using the SAFER Technique
Children submitted to fetoscopic in utero myelomeningocele repair using the SAFER (Skin-over-biocellulose for Anternatal FEtoscopic Repair) technique will evaluate at 30 months or more, regarding ambulation, neurodevelopment…
- Conditions
- Open Spina Bifida, Myelomeningocele, Meningomyelocele, Chiari Malformation With Spina Bifida
- Trial name
- NCT04356703
- Testing
- Neuropsicomotor developmental test
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital Israelita Albert Einstein
Skin Cancer, Mohs Micrographic Surgery
Mohs Micrographic Surgery and Reconstruction in the Optum Insurance Claims Database
Mohs micrographic surgery (MMS) followed by skin reconstruction has been widely accepted for treatment of many skin cancers. To further characterize the trends in MMS and reconstruction for skin cancer, a retrospective analysis…
- Conditions
- Skin Cancer, Mohs Micrographic Surgery, Interpolated Flap Repair
- Trial name
- NCT04117373
- Where
- United States
- Sponsor
- University of Pennsylvania
Umbilical Hernia, Epigastric Hernia
Long-term Recurrence and Other Complications Requiring Surgery Following Primary Ventral Hernia Repair
Nationwide, registry based cohort studies on all complications requiring surgery following primary ventral hernia repair
- Trial name
- NCT06783036
- Where
- Denmark
- Volunteers
- 7,200 people
- Sponsor
- Bispebjerg Hospital
Post Operative Pain
Comparative Study Between Ultrasound Guided Quadratus Lumborum Versus Ilioingunial/ Iliohypogastric Nerves Block as Post-operative Analgesia for Patients Undergoing Inguinal Hernia Repair Surgeries
Postoperative pain management is becoming an integral part of anesthesia care. Various techniques of pain relief have been designed.
- Trial name
- NCT06661707
- Testing
- Sonar guided Quadratus Lumborum block, Sonar guided Ilioinguinal/Iliohypogastric block
- Volunteers
- 44 people
- Sponsor
- Ain Shams University
Skin Carcinoma
A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer
This clinical trial studies whether a disposable negative pressure wound therapy (dNPWT) device, SNaP Wound Care System (Ultraportable Mechanically Powered Negative Pressure Wound Therapy) (SNaP), promotes wound healing in the…
- Trial name
- NCT07032701
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Sedation, Emergence Delirium
Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate
To compare the efficacy of the pre-operative nebulization of a combination of dexmedetomidine and ketamine versus nebulization of dexmedetomidine alone for sedation and prevention of emergence delirium in children undergoing…
- Trial name
- NCT05821972
- Testing
- Nebulization of dexmedetomidine and ketamine, Nebulization of dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Pain, Postoperative
Short and Long-term Effects of Surgical Repair of Pectus Deformities
A large number of institutions have reported their early results with minimally invasive repair of pectus excavatum and open repair of pectus carinatum, but only few have addressed the outcomes relevant to the concerns of the…
- Trial name
- NCT01329120
- Testing
- Minimally invasive repair of pectus excavatum, Open surgical repair of pectus carinatum
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- University of Aarhus
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