Clinical trials: Surgical Wound Healing
Hernia, Inguinal
Study of Surgical Mesh for Inguinal Hernia Repair
The purpose of this study is to assess the early outcomes when using the Biomerix Revive™ as a tension-free onlay patch, Lichtenstein-style, in patients who are candidates for primary, unilateral, open inguinal hernia repair.
- Trial name
- NCT00924755
- Testing
- Biomerix Revive™ (surgical mesh for inguinal hernia repair)
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Biomerix
General Surgery, Inguinal Hernia
Normal and Small Size Mesh in Open Inguinal Herni Repair
Recent years, lots of treatment teqnique have development. We aimed that comparising the normal and small size meshes in the inguinal hernia patients.
- Conditions
- General Surgery, Inguinal Hernia, Ventral Hernia
- Trial name
- NCT04269330
- Testing
- Comparison of normal and small size mesh in open inguinal hernia repair: Multicenter Prospective Randomized Controlled Trial.
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Konya Meram State Hospital
Rotator Cuff Tears, Postoperative Pain Management
Pain Education After Rotator Cuff Surgery
Study Title: The Effect of Pain Neuroscience Education Combined with Conventional Rehabilitation on Pain Management and Functional Outcomes in Patients Undergoing Mini-Open Rotator Cuff Repair Purpose: This study aims to…
- Conditions
- Rotator Cuff Tears, Postoperative Pain Management, Shoulder Dysfunction, Kinesiophobia (Fear of Movement)
- Trial name
- PNE-RCS (NCT06886932)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Elif Dilara Durmaz
Aortic Aneurysm
Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)
A multi-center, randomized clinical trial that will compare endovascular repair with standard open surgery in the repair of abdominal aortic aneurysms (AAA).
- Trial name
- OVER (NCT00094575)
- Testing
- Endovascular Repair, Standard Open Repair
- Where
- 42 sites in United States
- Volunteers
- 881 people
- Sponsor
- VA Office of Research and Development
Basal Cell Carcinoma, Squamous Cell Carcinoma
Absorbable Suture Versus Tissue Glue to Repair Defects Following Mohs Surgery
The purpose of the study is to look at which nonpermanent superficial closure method, cyanoacrylate tissue glue or fast absorbing gut suture, leads to a better cosmetic and functional outcome in repairs of facial wounds after…
- Trial name
- NCT01298167
- Testing
- Cyanoacrylate tissue glue versus Fast absorbing gut
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Yale University
Pelvic Organ Prolapse
Prospective Assessment of Robotic Sacrocolpopexy: a European Multicentric Cohort (PARSEC)
The purpose of this study is to prospectively assess the outcomes of robotic sacrocolpopexy for repair of pelvic organ prolapse in high volume european centers.
- Trial name
- PARSEC (NCT01598467)
- Testing
- Robotic assisted sacrocolpopexy (RASC)
- Where
- Ireland
- Volunteers
- 300 people
- Sponsor
- Femke van Zanten
Heart Valve Diseases, Mitral Valve Insufficiency
Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Organic MR
Surgical treatment is the only approach with potentially defined clinical success for organic mitral valve (MV) regurgitation. Recurrent or persistent complaints after initial successful MV repair is a clinical challenge in…
- Conditions
- Heart Valve Diseases, Mitral Valve Insufficiency, Heart; Dysfunction Postoperative, Cardiac Surgery, Heart; Disease, Mitral(Valve)
- Trial name
- SEP (NCT02371863)
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- UMC Utrecht
Surgical Wound, Wound Heal
Evaluating the Outcomes for Incisional Application of Negative Pressure for Nontraumatic Amputations
The purpose of this study is to evaluate how well subjects heal after surgery who receive standard dressings or incisional negative pressure wound therapy for non-traumatic amputation sites.
- Conditions
- Surgical Wound, Wound Heal, Amputation
- Trial name
- NCT03250442
- Testing
- PrevenaTM Device, Standard Dry Dressing
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Urinary Retention, Pelvic Organ Prolapse
Early Versus Late Voiding Trials After Prolapse Repair
The primary aim of this study is to determine if normal bladder function (the ability to empty the bladder during spontaneous urination) after surgical repair of pelvic organ prolapse returns faster in patients who have a…
- Trial name
- NCT02739256
- Testing
- Retrograde voiding trial
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Pittsburgh
Ureteral Stent Occlusion, Exposure Laser
Recovery Following Desflurane Versus Sevoflurane for Outpatient Urologic Surgery in Elderly Females
Numerous studies demonstrate that patients have improved immediate recovery characteristics following desflurane anesthesia compared to other volatile agents, including sevoflurane.
- Conditions
- Ureteral Stent Occlusion, Exposure Laser, Ureterostomy; Functional Disturbance, Vaginal Diseases
- Trial name
- NCT01310582
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hahnemann University Hospital
Chronic Periodontitis, Chronic Periodontitis Wth Diabetes Mellitus
Metabolic Regeneration Registry for Periodontal Health (20-Patient Cohort).
This observational study documents the clinical outcomes of a proprietary, safe-to-swallow metabolic protocol for chronic gum disease.
- Conditions
- Chronic Periodontitis, Chronic Periodontitis Wth Diabetes Mellitus, Non-surgical Periodontal Treatment, Gingival Regeneration
- Trial name
- NCT07538661
- Testing
- Nutraceutical Bio-Active Oral Repair Formula (Food-Grade), Nutraceutical Bio-Active Oral Repair Formula
- Where
- Algeria
- Volunteers
- 20 people
- Sponsor
- Amar h Zireg
Ventral Hernia, Post-mastectomy Breast Reconstruction
Analysis and Characterization of Biologic Implants
The purpose of this study is to investigate what happens to biologic mesh in the body over time on a molecular level. To date, it is not known what agents, enzymes, or proteins are interacting at the implantation site that…
- Trial name
- NCT01060046
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Washington University School of Medicine
Gingival Recession
Platelet Rich Fibrin in the Treatment of Palatal Wounds
In this study it will be investigated the usefulness of Platelet-Rich Fibrin (PRF) on in the epithelialized connective tissue graft palatal donor site healing acceleration and in the patient's morbidity reduction.
- Trial name
- NCT02438046
- Testing
- Palatal wound bandage
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Wound of Skin, Abdominal Wound
Safety and Efficacy of MRG-001 in Wound Healing in Abdominoplasty Patients
Surgical excisions are one of the most frequent cutaneous wounds. This study will compare the safety and preliminary efficacy of a novel fixed-dose combination drug MRG-001 in pre-abdominoplasty surgical excisions and scar…
- Trial name
- NCT05844527
- Testing
- MRG-001, Saline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- MedRegen LLC
Stress Incontinence, Female
Vaginal Elasticity Assessment Before and After Surgical Repair for Urinary Stress Incontinence.
Female patients with USI will be evaluated for vaginal elasticity using vaginal tactile imaging both before and after surgery for the repair of the USI.
- Trial name
- NCT03301818
- Testing
- Vaginal tactile imager
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- Rambam Health Care Campus
Head and Neck Cancer
Pre- and Postoperative Nutrition in Head and Neck Cancer Patients
The purpose of the project is to investigate the effect of wound healing of a combined pre- and postoperative oral supplement, consisting of zinc, vitamin C, arginine and multivitamin, as a supplement for adequate nutrition in…
- Trial name
- NCT03531190
- Testing
- Nutritional supplement (Protein + MIX), Nutritional supplement (Protein)
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Copenhagen
Axillary Hidradenitis Suppurativa
Perforator Flaps for Axillary Hidradenitis Suppurativa
Hidradenitis Suppurativa (HS) is a recurrent inflammatory disease (< 2 episode /6 months) with 1%-4% prevalence in Europe. Suppurating lesions are painful and involve one or more regions (axilla, genitofemoral, perineum, gluteal…
- Trial name
- HS-PAX (NCT03784313)
- Testing
- skin repair by axillary perforator flaps, skin repair by secondary wound healing
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mitral Valve Surgical Approaches
Transseptal Approach Versus Conventional Left Atrial Approach for Mitral Valve Procedures
Study Objectives/Specific Aims Overall Goal: To compare between transseptal approach and the conventional left atrial approach for mitral valve procedures.
- Trial name
- NCT04078100
- Testing
- Transseptal approach.
- Volunteers
- 100 people
- Sponsor
- Assiut University
Rotator Cuff Tears, Shoulder Surgery
Regeneten Patch vs Standard Care in Partial Thickness Rotator Cuff Repair
Shoulder pain is a common complaint with the most common reason being tendinopathy and/or tearing of the rotator cuff. While many rotator cuff tears are often considered normal, age-related degenerative disorders, with either…
- Trial name
- NCT04673344
- Testing
- Regeneten Collagen Patch
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Shoulder Instability
Modified PENG Plus Suprascapular Nerve Block Versus Interscalene Block for Bankart and Latarjet Surgery
This randomized controlled trial aims to compare the analgesic efficacy and safety of a Modified Pericapsular Nerve Group (PENG) Block combined with Suprascapular Nerve Block (SSNB) versus Interscalene Brachial Plexus Block (ISB)…
- Trial name
- NCT07689045
- Testing
- • Modified PENG Block combined with Suprascapular Nerve Block, • Interscalene Brachial Plexus Block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
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