Clinical trials: Surgical Wound Healing
Umbilical Hernia, Inguinal Hernia
The Impact of Medical Clowning on Pain and Stress Level in Pediatric Patients Undergoing Hernia Repair Surgery LAUGH Study.
The purpose of our study to quantitatively examine the stress levels prior to surgery and the use of analgesics post surgery in both children and their parents following a preoperative intervention with a medical clown compared…
- Trial name
- NCT01622218
- Testing
- Medical Clown
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Soroka University Medical Center
Congenital Heart Disease, Pulmonary Hypertension
Early Postoperative Triple Targeted Therapy in Patients With CHD-PAH in the "Grey Zone"
The purpose of this study is to observe the efficacy of early application of triple targeted drug therapy, including trilostane, in patients with congenital heart disease who are in the "gray zone" of preoperative evaluation…
- Trial name
- NCT07844213
- Testing
- Control group (ambrisentan plus tadalafil or macitentan plus tadalafil), Treatment group (ambrisentan plus tadalafil plus treprostinil or macitentan plus tadalafil plus treprostinil)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- China National Center for Cardiovascular Diseases
Leg Ulcer, Diabetic Foot Ulcer
Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, Leia
The purpose of this reseach study is to determine Mölnlycke Health Care´s Leia dressing performance properties is fulfilled and that the dressing is safe when used on wound types such as pressure ulcer, leg ulcer, and diabetic…
- Conditions
- Leg Ulcer, Diabetic Foot Ulcer, Pressure Ulcer
- Trial name
- NCT01966380
- Testing
- Leia
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Molnlycke Health Care AB
Hernia Abdominal Wall, Botox Injection
Preoperative BOTOX® Injection for Large Ventral Hernia Repair
This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection of a medicine commonly known as "BOTOX®" (onabotulinumtoxinA) into the…
- Conditions
- Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome
- Trial name
- PRETOX (NCT07220382)
- Testing
- OnabotulinumtoxinA Injection, OnabotulinumtoxinA, 0.9 % Normal Saline
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- The Cleveland Clinic
Anterior Cruciate Ligament Tear
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) that promotes reattachment and healing of the ACL…
- Trial name
- BEAR-MOON (NCT03776162)
- Testing
- ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Cryotherapy Effect, Post Operative Pain
Cryoanalgesia and Post-thoracotomy Pain in Minimally Invasive Cardiothoracic Surgery
Minimally invasive cardiothoracic surgery is often associated with chronic pain syndrome, out of keeping with the extent of surgical dissection.
- Trial name
- NCT05255146
- Testing
- Atricure Inc. Nitrous oxide Cryoprobe
- Sponsor
- University of Alberta
Rotator Cuff Tear, Rotator Cuff Repair of the Shoulder
The Contribution of Platelet-Rich Plasma to the Surgical Treatment of Rotator Cuff Tear: An Experimental Study
Purpose of the study: The aim of the study is to determine whether the postoperative administration of biological therapy with autologous platelet-rich plasma improves the clinical, imaging, and biochemical outcomes following…
- Conditions
- Rotator Cuff Tear, Rotator Cuff Repair of the Shoulder, PRP Injection
- Trial name
- NCT07689383
- Testing
- Arthroscopic repair of shoulder rotator cuff tear, PRP injection
- Where
- Greece
- Volunteers
- 51 people
- Sponsor
- KAT General Hospital
Anterior Ilıac Block, Hernia Surgery
Effect of Anterior Iliac Block on Postoperative Analgesia and Patient Satisfaction in Inguinal Hernia Repair Surgery
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide and presents challenges in anesthesia selection and postoperative pain management.
- Conditions
- Anterior Ilıac Block, Hernia Surgery, Spinal Anesthesia
- Trial name
- NCT07533383
- Testing
- Anterior Iliac Block, Control Group (A):
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Periodontitis
Effect of Fibrin Sealant on Early Wound Healing
The aim of this randomized controlled clinical trial is to compare wound healing after the use of fibrin sealant and sutures for gum surgeries.
- Trial name
- FS (NCT01538927)
- Testing
- Fibrin Sealant, Suture
- Where
- India
- Volunteers
- 15 people
- Sponsor
- Chhattisgarh Dental College and Research Institute
Scar, Breast Neoplasms
Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery
All patients undergoing breast biopsy, lumpectomy, needle-localization-guided breast biopsy, and mastectomy at Einstein Medical Center Philadelphia, Einstein Medical Center Montgomery, Center One, or Einstein Elkins Park will be…
- Conditions
- Scar, Breast Neoplasms, Breast Diseases, Surgical Wound
- Trial name
- NCT04554316
- Testing
- Steri-strip
- Where
- 2 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Flexor Tendon Injury
Virtual Reality Combined With Active Mobilization Post Flexor Tendon Repair
The purpose of this study is to evaluate the efficacy of combining IVR-based rehabilitation with a controlled early active mobilization protocol on functional outcomes, digit range of motion, grip strength, pinch strength and…
- Trial name
- NCT07875452
- Testing
- active mobilization, active mobilization plus IVR-based rehabilitation.
- Where
- 2 sites in Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Inguinal Hernia, Primary
The Outcome After Lichtenstein Operation vs. ProGrip Patch Repair of Inguinal Hernia
For the present study, 400 consecutive men with unilateral primary inguinal hernia are randomized to Lichtenstein repair using either light weight polypropylene mesh (38g/m2) or light weight ProGrip mesh.
- Conditions
- Inguinal Hernia, Primary, Unilateral
- Trial name
- NCT01026935
- Testing
- Open inguinal hernia repair
- Where
- 2 sites in Finland
- Volunteers
- 398 people
- Sponsor
- Helsinki University Central Hospital
Intertrochanteric Fractures
Blocks for Intertrochanteric Fracture Repair Surgery
This single-center open label study compares the outcomes of surgical repair of intratrochanteric fracture under general anesthetic or peripheral nerve blocks.
- Trial name
- NCT04470115
- Testing
- General anesthesia, Regional anesthesia- femoral and lateral femoral cutaneous nerve blocks
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Military Institute od Medicine National Research Institute
Acute Achilles Tendon Rupture
Popliteal Nerve Block for Acute Achilles Tendon Rupture Repair Surgery
Achilles tendon rupture is common, yet the value of popliteal nerve block for postoperative pain control during surgical repair remains uncertain.
- Trial name
- NCT06886815
- Testing
- Popliteal Nerve Block
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Women's College Hospital
Developmental Dysplasia of the Hip
Ultrasound Quadratus Lumborum Block Vs Fascia Iliaca Block in Pediatrics Undergoing Hip Surgery .
Comparison between ultrasound guided transmuscular QL block and Fascia iliaca block in pediatric patients undergoing DDH surgery regarding the quality of pain control in the perioperative period..
- Trial name
- NCT05282849
- Testing
- ultrasound guided fascia iliaca block, ultrasound guided quadratus lumborum block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Wound Healing, Acute Skin Wounds
Study of LUT017 Gel to Improve Healing of Skin Wounds After Removal of Benign Lesions in Healthy Adults
This is a Phase 1 research study evaluating the safety and potential benefits of a topical gel called LUT017 in helping skin wounds heal after minor skin procedures.
- Trial name
- NCT07463378
- Testing
- LUT017,Topical BRAF inhibitor
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Antoni Ribas
Post-surgical Oral Wounds, Oral Cavity Surgery
Evaluation of the Performance and Safety of a Linear Hyaluronic Acid-Based Medical Device in the Treatment of Surgical Wounds in the Oral Cavity.
The PR-DENT study is an interventional, single-center, controlled clinical investigation aimed at evaluating the clinical performance and safety of a Class III medical device based on linear hyaluronic acid for the treatment of…
- Conditions
- Post-surgical Oral Wounds, Oral Cavity Surgery, Wound Healing/Regeneration, Dental Extraction Sites
- Trial name
- PR-DENT (NCT07421934)
- Testing
- Intervention: Linear Hyaluronic Acid (Gumblast), Control: Standard Surgical Procedure
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- The Wave Innovation Group s.r.l.
Laceration of Skin
Evaluation of Zip Device to Conventional Sutures for Laceration Repair in Pediatrics in an Emergency Department
A prospective, randomized, controlled post-market clinical investigation that will enroll pediatric subjects requiring laceration repair.
- Trial name
- ZIPPED (NCT04122859)
- Testing
- Zip Skin Closure Device
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- ZipLine Medical Inc.
Peripheral Nerve Injury
Enhancement of Functional Recovery After Peripheral Nerve Injury With Tacrolimus
Tacrolimus (FK506) is an immunosuppressive medication that promotes organ allograft survival. It has also been shown to enhance nerve regeneration and muscle reinnervation in animals but these properties have not previously been…
- Trial name
- NCT00950391
- Testing
- Tacrolimus
- Sponsor
- Washington University School of Medicine
Periodontal Disease, Periodontal Disease Stage 2
ABX Versus CHX in NSPT
The study aims to compare the efficacy of a novel mouthwash based on microRepair ABX and an antibacterial complex with that of 0.12% chlorhexidine, both used as adjuncts to scaling and root planing.
- Conditions
- Periodontal Disease, Periodontal Disease Stage 2, Periodontal Disease, AVDC Stage 3
- Trial name
- ABXvsCHX (NCT07520968)
- Testing
- ABX Mouthwash as adjunctive to non surgical periodontal treatment, CHX as adjunctive to non surgical periodontal treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
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