Clinical trials: Surgical Wound Healing
Aortic Arch, Aortic Diseases
CILCA Arch Registry: Management and Outcomes of Open and Endovascular Repair
This registry aims to provide insights on the pathogenic mechanisms that expose subjects with CILCA arch to the increased risk of postoperative complications.
- Conditions
- Aortic Arch, Aortic Diseases, Bovine Arch
- Trial name
- NCT04995640
- Testing
- open cardiovascular repair or endovascular treatment (TEVAR)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Ospedale San Donato
Rotator Cuff Syndrome
Effects of Interscalene Block on Visual Clarity in Arthroscopic Surgery
Arthroscopic rotator cuff repair (RCR) has become the predominant technique for managing patients with full-thickness rotator cuff tears.
- Trial name
- NCT06786013
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Facial Paralysis
A Study of NTX-001 in the Treatment and Prevention of Facial Paralysis Requiring Surgical Repair.
This study involves the use of an Investigational Product called NTX-001. It is a product used in the repair of nerve injuries. It is used in the operating room.
- Trial name
- NCT05293522
- Testing
- NTX-001
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- Neuraptive Therapeutics Inc.
Periodontitis, Wound Healing
Effectiveness of Three Different Mouthrinses in Dental Plaque Control and Early Wound Healing
Aim: This study compared the effectiveness of three different mouthrinses (alcohol and non-alcohol chlorhexidine, alkyl dimethyl glycine / alkyl dimethyl amine oxide - C31G) in plaque control and early wound healing…
- Trial name
- NCT03119831
- Testing
- Alcohol-based Chlorhexidine Gluconate 0.12%, Alcohol-free Chlorhexidine Gluconate 0.12%, C31G
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Vascular Diseases, Peripheral Arterial Disease
Post-market, Prospective Evaluation of PHOTO-oxidized Bovine Pericardium in Vascular Surgery
The objective of this post-market clinical follow-up study is to evaluate the clinical outcomes of patients receiving PhotoFix as a patch within a vascular repair or reconstruction procedure.
- Conditions
- Vascular Diseases, Peripheral Arterial Disease, Hemodialysis Access Failure (Disorder), Carotid Artery Diseases
- Trial name
- PHOTO-V (NCT03669042)
- Testing
- PhotoFix
- Where
- 9 sites in United States
- Volunteers
- 94 people
- Sponsor
- Artivion Inc.
Myocardial Protection, Minimally Invasive Surgery
Myocardial Protection in Minimally Invasive Mitral Valve Surgery
Perfusion strategies and aortic clamping techniques for right mini-thoracotomy mitral valve (MV) surgery have evolved over time and remarkable short- and long-term results have been re-ported.
- Conditions
- Myocardial Protection, Minimally Invasive Surgery, Mitral Valve Prolapse
- Trial name
- NCT04231903
- Testing
- Aortic clamp
- Volunteers
- 116 people
- Sponsor
- University of Turin, Italy
Achilles Tendon Rupture, Achilles Tendon Surgery
Use of Blood Flow Restriction Therapy in Perioperative Rehabilitation Following Achilles Tendon Rupture
The purpose of this study is to examine the effect of utilizing blood flow restriction (BFR) therapy in the rehabilitation of Achilles tendon rupture (ATR).
- Trial name
- NCT04492059
- Testing
- Blood flow restriction augmented physical therapy, Physical therapy
- Where
- United States
- Sponsor
- Henry Ford Health System
Frozen Shoulder, Rotator Cuff Tears
Preoperative Psychological Risk Factors for the Retractable Capsulitis of the Shoulder After Shoulder Rotator Cuff Repair Surgery
The main objective of our study is to determine whether preoperative anxiety, depression and kinesiophobia are risk factors for retractile capsulitis after arthroscopic rotator cuff repair to best support these patients.
- Trial name
- NCT04044196
- Testing
- Rotator cuff repair
- Where
- 2 sites in France
- Volunteers
- 77 people
- Sponsor
- Hospital Ambroise Paré Paris
Incisional Hernia, Surgical Wound Infection
Prophylactic Negative Pressure Wound Therapy for Patients Undergoing Incisional Hernia Repair
The study will examine the effect of using Negative Pressure Wound Therapy (NPWT) compared with standard wound dressing among patients undergoing elective open surgery for incisional hernia.
- Conditions
- Incisional Hernia, Surgical Wound Infection, Surgical Site Infection, Quality of Life
- Trial name
- PROPRESS (NCT05050786)
- Testing
- Negative Wound Pressure Therapy (Prevena(TM)), Standard Wound Dressing
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Kristian Kiim Jensen
Wound Healing, Wound Healing Complication
Sutureless Versus Conventional Suturing in Oral Surgery
This randomized clinical study compares sutureless wound closure using n-butyl-2-cyanoacrylate tissue adhesive with conventional silk suturing following minor oral surgical procedures.
- Conditions
- Wound Healing, Wound Healing Complication, Postoperative Pain, Oral and Maxillofacial Surgery Complications
- Trial name
- NCT07856524
- Testing
- Sutureless Wound Closure Using n-Butyl-2-Cyanoacrylate, Conventional Suturing
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- Jouf University
Atrial Fibrillation New Onset, Hemorrhage
Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation
The aim of this study is to evaluate the prophylactic effects of Ranolazine on new onset atrial fibrillation in post-operative coronary artery bypass graft and valve surgery patient population at Staten Island University hospital.
- Conditions
- Atrial Fibrillation New Onset, Hemorrhage, Prolonged QTc Interval, Ventricular Tachycardia
- Trial name
- NCT01590979
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Surgical Site Infection
Surgical Site Infection After Episiotomy Repair Related to Routine Use of Antibiotic Prophylaxis in Low-Risk Population
Bacterial infections occurring during labor, childbirth, and the puerperium may be associated with considerable maternal and perinatal morbidity and mortality.
- Trial name
- NCT06154720
- Testing
- Antibiotics
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pelvic Organ Prolapse, Postoperative Pain Management
SORE Study: Sitz Baths After Urogynecologic Reconstruction
The purpose of this study is to evaluate the utility of postoperative sitz baths in patient pain perception and recovery following surgical repair of prolapse.
- Conditions
- Pelvic Organ Prolapse, Postoperative Pain Management, Gynecologic Surgeries
- Trial name
- SORE (NCT07215780)
- Testing
- Sitz Bath
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Yale University
Impaired Wound Healing, Factor XIII Deficiency
Wound Healing Abnormalities in Major Abdominal Surgery
This clinical observational study investigates the incidence of wound healing abnormalities in patients undergoing major abdominal surgery.
- Trial name
- INWOUND (NCT00735579)
- Where
- Germany
- Volunteers
- 260 people
- Sponsor
- Klinikum St. Georg gGmbH
Umbilical Hernia, Ventral Hernia
Natural Orifice Translumenal Endoscopic Surgery (NOTES): Laparoscopic Assisted Transvaginal Ventral Hernia Repair
This is a prospective chart review/data collection study of natural orifice translumenal endoscopic surgery (NOTES) for ventral hernia repair, that will include questionnaires administered throughout the study.
- Trial name
- NOTES (NCT01398215)
- Testing
- transvaginal NOTES ventral hernia repair
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Popliteal Artery Aneurysm
Open Versus Endovascular Repair of Popliteal Artery Aneurysm Trial
Weakness in the wall of a blood vessel located behind the knee (popliteal artery) which leads to a swelling of this blood vessel (aneurysm) is one of the most common types of arterial aneurysms.
- Trial name
- OVERPAR (NCT01817660)
- Testing
- Open repair of popliteal artery, Endovascular repair of popliteal artery
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Boston Medical Center
Shoulder
Driving After Shoulder Surgery
Patients undergoing a shoulder arthroplasty or rotator cuff repair will be enrolled in the study. Patients will be asked to undergo driving simulator assessments post-operatively in ATI Physical Therapy pre-operatively through 9…
- Trial name
- NCT04196218
- Testing
- Driving simulator
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Hawkins Foundation
Healing Wound, Iron-deficiency
Impact of Iron Stores on Wound Healing in Plastic Surgery
In breast reduction surgery, delayed wound healing may increase surgical site infections, cutaneous necrosis and may be related to psychological harm.Some risk factors have been identified : smoking, diabetes, overweight.
- Conditions
- Healing Wound, Iron-deficiency, Surgical Wound
- Trial name
- IRONPLAST (NCT04276168)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Wound Healing
Comparison of Wound Healing Duration Between Vacuum-Assisted Closure (VAC) and Conventional Dressings
This randomized controlled trial will compare vacuum-assisted closure (VAC) therapy with conventional wound dressings for the treatment of open contaminated and dirty wounds.
- Trial name
- VAC-WOUND (NCT07832162)
- Testing
- Vacuum-Assisted Closure (VAC) Therapy Description:, Conventional Wound Dressing
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jinnah Postgraduate Medical Centre
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