Clinical trials: Surgical Wound Healing
Mucopolysaccharidosis (MPS)
Mucopolysaccharidosis (MPS) I, II, and VI Screening in a High-Risk Population With Previous Surgical Repair or Presence of Inguinal and/or Umbilical Hernia in Combination With Pediatric ENT Surgery (The HATT Project)
Mucopolysaccharidosis (MPS) type II (MPS II; Hunter syndrome) is a rare, X-linked disease caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase (I2S) and occurs almost exclusively in boys, with an incidence of…
- Trial name
- NCT02095015
- Where
- 14 sites in United States, Canada and 5 more
- Volunteers
- 159 people
- Sponsor
- Shire
Obesity, Bariatric Surgery Candidate
Crural Repair During Laparoscopic Sleeve Gastrectomy in Patients With a Lax Gastroesophageal Junction
Background: Laparoscopic sleeve gastrectomy (LSG) is one of the commonest bariatric procedures. However, it is associated with postoperative gastroesophageal reflux disease (GERD) and erosive esophagitis (EE).
- Conditions
- Obesity, Bariatric Surgery Candidate, Esophagus Injury, Gastroesophageal Reflux
- Trial name
- REPAIR (NCT05330910)
- Testing
- Laparoscopic sleeve gastrectomy with concomitant hiatal hernia repair arm, Laparoscopic sleeve gastrectomy arm
- Where
- 2 sites in Singapore
- Volunteers
- 96 people
- Sponsor
- Sengkang General Hospital
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Thyroid Disease
Platysma Trial - Platysma Suturing Versus no Sutures for Wound Closure After Primary Thyroid Surgery
Influence of the platysma suture on postoperative pain and wound healing.
- Trial name
- Platysma (NCT02951000)
- Testing
- platysma suture, no platysma suture
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Impaired Wound Healing
Secondary Intention Wound Healing Versus Micrografting in Patients Undergoing Mohs Surgery
This study evaluates a novel micrografting technique to see how it will influence the healing rate and cosmetic result of second intention wounds.
- Trial name
- MomelanMohs (NCT01442844)
- Testing
- Micrografting
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Massachusetts General Hospital
Urethral Stricture, Surgery
VeSpAR: Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Strictures.
The investigators want to verify whether the surgical outcome of vessel-sparing anastomotic repair in isolated short bulbar urethral strictures is not inferior to the surgical outcome of transecting anastomotic repair.
- Conditions
- Urethral Stricture, Surgery, Urologic Diseases
- Trial name
- VeSpAR (NCT03572348)
- Testing
- Transecting anastomotic repair (tAR), Vessel-sparing anastomotic repair (vsAR)
- Where
- 13 sites in United States, Argentina and 6 more
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Post Operative Pain
Bunionectomy Trial With GRT6005
The purpose of the trial is to determine whether the new centrally acting analgesic is effective in comparison to placebo and an active comparator (morphine).
- Trial name
- NCT00872885
- Testing
- GRT6005, Morphine
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Tris Pharma, Inc.
Surgical Flaps, Skin Pigmentation
Evaluation of the Postoperative Effect of Expanded Pedicled Deltopectoral Flap to Repair the Facial-Cervical Scars
This study evaluates the effect of Expanded Pedicled Deltopectoral Flap on facial-cervical scars repair, including flap sensation, L*a*b* value,flap's elasticity,melanin content, hemoglobin content, and evaluation of scar and…
- Conditions
- Surgical Flaps, Skin Pigmentation, Sensory Defect
- Trial name
- NCT03735641
- Testing
- Expanded Pedicled Deltopectoral Flap
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Type A Aortic Dissection
Impact of RIVP on GI Function in Patients Undergoing Surgical Repair for ATAAD
Acute Type A Aortic Dissection (ATAAD) is a serious medical condition that requires immediate surgical intervention. The repair of Acute Type A Aortic Dissection (ATAAD) combines different surgical procedures, including the use…
- Trial name
- NCT06434987
- Testing
- Retrograde Inferior Vena Cava Perfusion, Antegrade cerebral perfusion
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Rotator Cuff Tear Surgical Repair
H-Wave® Device Stimulation for Post-operative Rotator Cuff Repair Surgery
The goal of this intent-to-treat study is to evaluate the efficacy of H-Wave Device Stimulation following rotator cuff repair surgery.
- Trial name
- NCT07501949
- Testing
- Routine post-surgical care plus H-Wave® Device Stimulation (HWDS), Routine post-surgical care
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Electronic Waveform Lab
Carotid Endarterectomy
Blood Flow Evaluation After Carotid Surgical Treatment
Approximately 20% of strokes originate from the rupture of an atherosclerotic plaque in the carotid artery. Surgical revascularization, i.e.
- Trial name
- BEAT (NCT06827509)
- Testing
- Ultrasound-based flow imaging
- Volunteers
- 40 people
- Sponsor
- Rijnstate Hospital
Ventral Hernia
Gentrix® Surgical Matrix for Soft Tissue Reinforcement in Ventral Hernia Repair
The purpose of this study is to collect additional safety data and demonstrate the performance of Integra Gentrix® Surgical Matrix for reinforcement of ventral hernia repairs.
- Trial name
- NCT05610267
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Integra LifeSciences Corporation
Torn Menisci
Balance in Patients After Surgery for Torn Meniscus
The important role of the menisci in knee function and in preserving knee health has been shown in several studies. Additionally to principal functions of load transmission and shock absorption, meniscus contributes to knee joint…
- Trial name
- NCT00256971
- Testing
- meniscectomy
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Hadassah Medical Organization
Atrial Functional, Mitral Regurgitation (MR)
PRECISE-AFMR I: Transcatheter Mitral Valve Edge-to-Edge Repair for Atrial Functional Mitral Regurgitation in Patients at High Surgical Risk
Atrial functional mitral regurgitation (AFMR) develops when enlargement and remodeling of the left atrium and mitral annulus prevent the mitral valve leaflets from closing completely, allowing blood to leak backward through the…
- Trial name
- PRECISE-AFMR I (NCT07741253)
- Testing
- Transcatheter Edge-to-Edge Repair
- Where
- China
- Volunteers
- 182 people
- Sponsor
- China National Center for Cardiovascular Diseases
Cerebrospinal Fluid Leakage, Subdural
Study to Evaluate Safety & Effectiveness of Spinal Sealant
To evaluate a spinal sealant as an adjunct to sutured dural repair compared to standard of care techniques.
- Trial name
- NCT00444067
- Testing
- Spinal Sealant, Standard of Care
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Integra LifeSciences Corporation
AKI
Protection From Acute Kidney Injury (AKI) With Basis™ Treatment
This study is a single-center, prospective, randomized, double-blinded, placebo-controlled phase II clinical trial to evaluate the efficacy of "NAD+ supplementation" with Basis™ (Nicotinamide Riboside and Pterostilbene) in…
- Trial name
- NCT04342975
- Testing
- Nicotinamide Riboside + Pterostilbene
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Aorta Dissection, Aorta Aneurysm
Hybrid Operation in Thoracic Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of different hybrid operations who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm, Stanford Type A…
- Trial name
- NCT01500395
- Testing
- Hybrid operation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Pain, Postoperative, Healing Surgical Wounds
Use of Cyanoacrylate in Healing and Pain in the Palatal Donor Site of Connective Tissue Grafts
Periodontal plastic surgery has been performed successfully for a long time in the treatment of gingival recessions and mucogingival defects.
- Trial name
- NCT06116539
- Testing
- Cyanoacrylate, Suture
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alfonso X El Sabio University
ACL Injury
Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery
Protein supplementation may promote increases in strength and hypertrophy in the context of resistance training (RT) and reduce markers of inflammation, while sufficient levels of protein are necessary for healing certain wounds…
- Trial name
- NCT03614351
- Testing
- Protein (PROT), Control (CONT)
- Sponsor
- Wake Forest University Health Sciences
Inguinal Hernia
Plasma Total Antioxidant Status and Thiobarbituric Acid-reacting Substances in Patients With Inguinal Hernia
Introduction: Any form of trauma, including surgery is known to result in oxidative stress. Single incision laparoscopy is a step forward towards almost scarless surgery.
- Trial name
- NCT02336256
- Testing
- Procedures of hernia repair.
- Volunteers
- 34 people
- Sponsor
- Poznan University of Medical Sciences
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