Clinical trials: Surgical Wound Infiltration
Pain
Multimodal Analgesia With Interfascial Continuous Wound Infiltration: A Randomized Clinical Trial
Objectives: For major laparoscopic surgery, as with open surgery a multimodal analgesia plan can help control postoperative pain.
- Trial name
- NCT02223533
- Testing
- 19Gx500-mm Pajunk InfiltraLong® catheter, morphine
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital Galdakao-Usansolo
Postoperative Pain
Quadroiliac Plane Block for Analgesia After Renal Transplantation
Renal transplantation is a major abdominal surgical procedure that may cause moderate to severe postoperative pain. Opioids are commonly used as part of multimodal analgesia; however, opioid-related adverse effects such as…
- Trial name
- NCT07716566
- Testing
- Ultrasound-Guided Quadroiliac Plane Block, Surgical Wound Infiltration With Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Colorectal Cancer, Postoperative Pain
Ultrasound-Guided Erector Spinae Plan Block for Colorectal Surgery
Colorectal cancer is a common and lethal disease. It still remains the third most common cause of cancer death in women and the second leading cause of death in men.
- Trial name
- NCT04313764
- Testing
- Bupivacaine Hcl 0.25% ESP block, Bupivacaine Hcl 0.25% infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Pain, Postoperative, Spinal Disease
Comparison of Ultrasound-guided Bilateral ESP Block and Wound Infiltration for Spinal Surgical Analgesia
The aim of our study is to determine the superior procedure in analgesia management by comparing the traditional wound infiltration technique with the ultrasound-guided bilateral erector spina plan block technique in spinal…
- Conditions
- Pain, Postoperative, Spinal Disease, Anesthesia, Local, Anesthesia, Regional
- Trial name
- NCT04642625
- Testing
- Visual Analog Score, patient satisfaction
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Lumbar Disc Disease
SPI-directed Analgesia for Lumbar Discectomy
The aim of this randomized trial is to assess the efficacy of analgesia for lumbar discectomy and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively.
- Trial name
- SPI (NCT02971540)
- Testing
- Metamizol, Tramadol, Bupivacaine
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Silesia
Coronary Artery Disease, Coronary Artery Stenoses
Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride
The aim of this study is to evaluate the analgesic efficacy and safety of wound infiltration with liposomal bupivacaine (LB) in patients undergoing cardiac surgery with sternotomy and cardiopulmonary bypass (CPB) and compare it…
- Conditions
- Coronary Artery Disease, Coronary Artery Stenoses, Valve Regurgitation, Mitral, Valve Regurgitation, Tricuspid
- Trial name
- NCT03270514
- Testing
- Exparel Injectable Product, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kathirvel Subramaniam
Thyroid Surgery
Comparison of Bupivacaine Wound Infiltration Versus Wound Instillation to Minimize Postoperative Pain After Thyroid Surgery
Pain management following thyroidectomies, which can cause mild to moderate postoperative pain, particularly in the first 24 hours following surgery, has received little attention .
- Trial name
- NCT06789575
- Testing
- Bupivacaine, Adrenaline, Lidocaine (drug)
- Volunteers
- 102 people
- Sponsor
- Assiut University
Rescue Analgesia
Comparison of Rescue Analgesia Requirement in Patients Undergoing Laparoscopic Cholecystectomy After Transversus Abdominal Plane (tap) Block Vs Local Anesthetic Wound Infiltration At the End of Surgery
patients undergoing laparoscopic cholecystectomy will be diveided into 2 groups A \& B . Group A will receive local anesthetic wound infiltration and group B will receive Transversus abdominal plane block as a post operative…
- Trial name
- TAP (NCT06803966)
- Testing
- Post Operative Analgesia
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Healing Surgical Wounds
Local Wound Infiltration Versus Caudal Block on Wound Infection and Healing in Paediatrics Inguinal Herniotomy
The aim of the present study is to assess effect of local wound infiltration in comparison with caudal block by bupivacaine 0.25% after inguinal herniotomy in pediatrics on: Wound infection and healing (primary outcome) and…
- Trial name
- NCT03563625
- Testing
- Caudal block, Wound infiltration, Bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- University of Alexandria
Ankle Fractures, Pain, Postoperative
Ropivacaine Versus Bupivacaine as Preemptive Analgesia in Surgical Site in Ankle Fracture Patients
Title: Ropivacaine versus Bupivacaine as Preventive Analgesia in Surgical Incision Site In Patients With Ankle Fracture Background: Ankle fractures are about 10% of the fractures associate to sports and with an incidence of 0.11…
- Conditions
- Ankle Fractures, Pain, Postoperative, Local Infiltration
- Trial name
- NCT02949674
- Testing
- Ropivacaine, Bupivacaine
- Where
- Mexico
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Pain, Postoperative, Pain, Acute Postoperative
Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery
Liposomal Bupivacaine (Exparel) has been recently studied as the active agent utilized in various nerve block. Due to its liposomal form allowing for extended delivery, Exparel has been used in various peri-operative nerve blocks…
- Conditions
- Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
- Trial name
- NCT05494645
- Testing
- Exparel, Peripheral Nerve Block
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- St. Luke's Hospital, Pennsylvania
Heart Surgery Via Sternotomy, Post-operative Analgesia
Advantage of Tramadol in Local Analgesia Post-Sternotomy
Sternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine.
- Trial name
- ATLAS (NCT02851394)
- Testing
- Levobupivacaine, tramadol
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Post Operative Pain, Bradycardia
Postoperative Analgesic Effectiveness of Bupivacaine With and Without Dexmedetomidine in Patients With Abdominal Surgery
Abdominal surgeries are major surgical procedures that are performed at any teaching hospital. Pain control is major concern in the intra-operative as well as post-operative period in these patients.
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Nausea
- Trial name
- NCT06531603
- Testing
- bupivacaine wound infilteration, Bupivacaine plus dexmedetomidine wound infilteration
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Sahiwal medical college sahiwal
Dyspnea, Pulmonary Edema
The Incidence of TRALI in Patients Undergoing Orthopedic-Oncology Surgery
Currently Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality in the United States, and one of major post-transfusion complications.
- Trial name
- NCT00914784
- Where
- Israel
- Volunteers
- 550 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Abdominal Cancer
Effect of Wound Infiltration by Ketamine Versus Dexmedetomidine Added to Bupivacaine on Surgical Stress
This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on stress response and postoperative pain in lower abdominal cancer surgery.
- Trial name
- NCT02927379
- Testing
- Dexmedetomidine, Ketamine, Bupivacaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Analgesia, Surgery
Transversus Abdominis Plane Block Compared to Local Anesthetic Wound Infiltration in Gynecologic Oncology Surgery
This study is being done to see if preoperative transversus abdominis plane (TAP) analgesia will provide similar postoperative pain control, hospital length of stay, and postoperative outcomes compared to surgeon-initiated wound…
- Trial name
- NCT06213454
- Testing
- TAP Anesthesia, Surgeon-Initiated Local Anesthetic
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Wisconsin, Madison
Postoperative Pain
Local Wound Infiltration in Renal Surgery
Multimodal analgesia is a rational approach to treat various components of postoperative pain.
- Trial name
- NCT03601780
- Testing
- local wound infiltration plus usual care, usual care only
- Volunteers
- 40 people
- Sponsor
- Assiut University
Post Operative Pain
Analgesia After Video-Assisted Thoracic Surgery
Although less invasive, postoperative analgesia remains challenging in patients undergoing uniportal video-assisted thoracic surgery (VATS).
- Trial name
- NCT05094323
- Testing
- Ultrasound-guided deep serratus anterior plane block with isobaric bupivacaine, Local wound infiltration with isobaric bupivacaine, Ultrasound-guided thoracic paravertebral block with isobaric bupivacaine
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Assiut University
Pain, Hip Fractures
PENG Block Plus Local Infiltration Compared to PENG Block Alone in Hip Surgery
Summary: Pain control after hip surgery is quite important for patients' recovery. Many regional techniques are available with the focus on motor sparing block to speed patient recovery.
- Conditions
- Pain, Hip Fractures, Postoperative Pain, Postoperative Analgesia
- Trial name
- NCT05773365
- Testing
- PENG block with or without local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Suez Canal University
Pain, Postoperative, Surgical Procedure, Unspecified
Randomized Trial of Wound Infiltration With Extended-release Bupivacaine Before Laparoscopic or Robotic Hysterectomy
The investigators are studying ways to improve pain control after surgery. One way to decrease pain is to inject incisions with a numbing medicine (local anesthetic) while in the operating room.
- Trial name
- NCT02352922
- Testing
- Liposomal Bupivacaine, Bupivacaine HCl
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- AdventHealth