Clinical trials: Survival , Tumor
Cancer
mHealth Physical Activity Intervention for Young Cancer Survivors
In this randomized controlled trial the investigators will determine whether a mobile health intervention can increase physical activity levels in AYA cancer survivors over a one year period.
- Trial name
- AYA-PACT (NCT04765241)
- Testing
- Physical Activity
- Where
- Canada
- Volunteers
- 287 people
- Sponsor
- AHS Cancer Control Alberta
Cancer, Metastatic, Cancer
Clinical and Functional Variables in Oncology
The aim is to analyse the effect of a Therapeutic Exercise and Education programme in several clinical and functional outcomes in cancer patient and survivors
- Conditions
- Cancer, Metastatic, Cancer, Survivorship
- Trial name
- Oncolab (NCT03879096)
- Testing
- Therapeutic Exercise and Education
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Malaga
Prostate Cancer
Androgen Deprivation Therapy for Oligo-recurrent Prostate Cancer in Addition to radioTherapy
The overall aim of this project is to test the hypothesis that the addition of ADT to metastasis-directed radiotherapy (MDRT) in well-selected PCa patients with oligo-metastatic disease prolongs the metastases progression-free…
- Trial name
- ADOPT (NCT04302454)
- Testing
- Radiotherapy, Leuprorelin
- Where
- 13 sites in Netherlands
- Volunteers
- 280 people
- Sponsor
- University Medical Center Groningen
Glioma
MR Based Survival Prediction of Glioma Patients Using Artificial Intelligence
This registry aims to collect clinical, molecular and radiologic data including detailed survival data, clinical parameters, molecular pathology (1p/19q codeletion, MGMT methylation, IDH and TERTp mutations, etc) and…
- Trial name
- NCT04215211
- Testing
- Survival prediction for glioma patients
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Disorder Related to Bone Marrow Transplantation, Leukemia
Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
The goal of this clinical research study is to learn if combining busulfan with clofarabine and fludarabine can help control the disease better than the previous standard method (using busulfan and fludarabine alone) in patients…
- Conditions
- Disorder Related to Bone Marrow Transplantation, Leukemia, Transplantation Infection
- Trial name
- NCT01471444
- Testing
- Fludarabine, Clofarabine, Busulfan
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- M.D. Anderson Cancer Center
Head and Neck Cancer, Esophageal Cancer Stage
Outcomes of A Novel Treatment Decision of Patients With Esophageal and Head and Neck Carcinoma Synchronously
To summarise the outcomes of a treatment decision of patients with superficial esophageal carcinoma synchronously associated with head and neck cancer, that is endoscopic treatment for the superficial esophageal carcinoma plus…
- Trial name
- NCT03450447
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Yanqing Li
Cancer Survivorship, Family Planning
Family Building Decision Support for Female Adolescent and Young Adult Cancer Survivors
This study aims to develop and pilot-test a nurse navigator-delivered behavioral program to support female adolescent and young adult (AYA) cancer survivors in making informed, values-driven family-building decisions after…
- Conditions
- Cancer Survivorship, Family Planning, Adolescent and Young Adult Cancer
- Trial name
- NCT07471685
- Testing
- Nurse Navigator-Delivered Family Building Decision Support, Survivorship Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Duke University
LUNG CANCER
An Observational Study on the Impact of the 23-valent Pneumonia Vaccine on Lung Cancer Patients
To evaluate the impact of the 23-valent pneumonia vaccine on the incidence of pulmonary infection and survival in lung cancer patients, and to explore its preventive effect and safety in the lung cancer patients.
- Trial name
- NCT07142057
- Testing
- 23-valent pneumococcal vaccine
- Volunteers
- 500 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Epithelial Ovarian Cancer, Circulating Tumor DNA
ctDNA Methylation for Epithelial Ovarian Cancer
Ovarian cancer is one of the most dangerous and predominant gynecological cancers, with a high cancer-related mortality rate in women.
- Conditions
- Epithelial Ovarian Cancer, Circulating Tumor DNA, DNA Methylation, Non-invasive Diagnosis
- Trial name
- NCT05801263
- Testing
- CDO1 and HOXA9 methylation assay
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Lei Li
Colorectal Neoplasms, Colorectal Carcinoma
FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status
To estimate progression-free survival at one year in elderly patients with RAS/BRAF wild-type unresectable mCRC and good performance status treated with FOLFIRI + panitumumab as first-line therapy.
- Conditions
- Colorectal Neoplasms, Colorectal Carcinoma, Colorectal Cancer Metastatic, Neoplasm Metastasis
- Trial name
- OPALO (NCT03142516)
- Testing
- Panitumumab, Irinotecan, Folinic acid
- Where
- 12 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Grupo Espanol Multidisciplinario del Cancer Digestivo
Diffuse Large B Cell Lymphoma
Follow-up the OS and PFS of Rituximab Biosimilar HLX01 and MabThera, in Untreated Subjects With CD20+ DLBCL
The main objective of this study is to observe the overall survival of Rituximab Biosimilar HLX01 and MabThera in Combination With CHOP, in previously untreated subjects with CD20+ DLBCL.
- Trial name
- NCT04491721
- Where
- China
- Volunteers
- 407 people
- Sponsor
- Chinese Academy of Medical Sciences
Lymphoma, Non-Hodgkin
Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study
The goal of this infrastructure protocol is to build and maintain a large and diverse observational cohort study to support broad and cutting-edge research focused on NHL prognosis and survivorship.
- Trial name
- LEO (NCT04996706)
- Where
- 12 sites in United States
- Volunteers
- 21,000 people
- Sponsor
- Mayo Clinic
Sarcoma, Survivorship
Quality of Life and Medical Care of Long-term Sarcoma Survivors in Germany (PROSa+)
The study PROSa+ aims to assess patient-reported outcomes (PROs), patient-reported experiences (PREs), and the socioeconomic situation of long-term sarcoma survivors (≥ 5 years post-diagnosis, with or without active disease) in…
- Conditions
- Sarcoma, Survivorship, Quality of Life (QOL), Medical Care
- Trial name
- PROSa+ (NCT07148193)
- Testing
- No intervention (observational study)
- Where
- 5 sites in Germany
- Volunteers
- 1,600 people
- Sponsor
- Technische Universität Dresden
Uterine Cervical Neoplasms
Immunotherapy Combined With Carbon Ion Radiotherapy for Locally Advanced Cervical Cancer
This study explores the therapeutic effect of carbon ion radiotherapy plus immunotherapy and chemotherapy for locally advanced cervical cancer.
- Trial name
- NCT07702838
- Testing
- Carbon ion external beam radiotherapy plus 3 courses of three-dimensional brachytherapy.
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhejiang Cancer Hospital
Prostate Cancer
Comparison of Radiation Therapy Regimens in Treating Patients With Localized Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which regimen of radiation therapy is more effective for prostate cancer.
- Trial name
- NCT00010244
- Testing
- radiation therapy
- Where
- 19 sites in France
- Volunteers
- 306 people
- Sponsor
- UNICANCER
Locally Advanced Pancreatic Adenocarcinoma, Borderline Resectable Pancreatic Carcinoma
Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC
The goal of this multicenter randomized controlled phase III trial is to compare two durations of neoadjuvant chemotherapy (NAT) with mFOLFIRINOX or gemcitabine-nab-paclitaxel (GnP) before attempt for surgical resection in…
- Conditions
- Locally Advanced Pancreatic Adenocarcinoma, Borderline Resectable Pancreatic Carcinoma, Pancreas Cancer, Neoadjuvant Chemotherapy
- Trial name
- ADVANTAGE (NCT06714604)
- Testing
- FOLFIRINOX or gemcitabine-nab-paclitaxel
- Where
- Sweden
- Volunteers
- 432 people
- Sponsor
- Sahlgrenska University Hospital
Breast Cancer
A Mixed-Methods Metabolomics Investigation of Lifestyle and Energy Balance During Breast Cancer Survivorship
The MILES Study is a longitudinal, mixed-methods investigation of urinary biomarkers, energy balance, and lifestyle modifications in diverse women during early breast cancer treatment.
- Trial name
- MILES (NCT07655934)
- Testing
- Survey completion, Urine specimen banking, Qualitative interviews
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Bladder Cancer, Non-Muscle Invasive Bladder Cancer (NMIBC)
Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC
The goal of this clinical trial is to learn whether a combination of two chemotherapy drugs, Gemcitabine and Docetaxel, can treat high-grade non-muscle-invasive bladder cancer (HG-NMIBC) in adults whose cancer failed conventional…
- Conditions
- Bladder Cancer, Non-Muscle Invasive Bladder Cancer (NMIBC), Urothelial Carcinoma, Carcinoma in Situ (CIS)
- Trial name
- NCT07322263
- Testing
- Intravesical Gemcitabine and Docetaxel
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Michael A. O'Donnell
Cancers
Cancer Survivor Registry: The Breast Cancer M.A.P. (Mind Affects the Physical) Project
Cancer Survivor Registry: The Breast Cancer M.A. P. (Mind Affects the Physical M.A.P.) Project to identify and help us understand the emotional and social needs of breast cancer survivors.
- Trial name
- NCT01295658
- Where
- United States
- Volunteers
- 3,729 people, healthy volunteers welcome
- Sponsor
- Cancer Support Community, Research and Training Institute, Philadelphia
Breast Cancer, Hot Flashes
Reproductive Health Survivorship Care Plan
The investigators propose to test the efficacy of the Reproductive Health Survivorship Care Plan (SCP-R), a novel survivorship care tool to meet the reproductive health needs of young breast cancer survivors (YBCS).
- Conditions
- Breast Cancer, Hot Flashes, Sexual Dysfunction, Fertility
- Trial name
- SCPR (NCT02667626)
- Testing
- Reproductive Health Survivorship Care Plan (SCPR), Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of California, San Diego
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.