Clinical trials: Survival , Tumor
Neoplasms, Blood Cancer
Take the Reins: The Effects of Nutrient Timing on Cancer-related Fatigue
Cancer-related fatigue affects at least 30-90% of patients with cancer, depending on the type of cancer and their treatment(s) (e.g., chemotherapy, radiation).
- Conditions
- Neoplasms, Blood Cancer, Fatigue, Diet Habit
- Trial name
- NCT06482515
- Testing
- Time-restricted eating, Nutrition counseling
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Maryland, Baltimore
Patient Reported Outcome Measures, Ovarian Neoplasms
The Possible Influence of Different Follow-up Modalities on Overall Survival in Ovarian Cancer
The study is designed as an observational cohort study, aiming to evaluate, whether a structured recording of symptoms by a mobile app contributes insight in the follow-up modalities of ovarian cancer patients.
- Trial name
- ECOvar (NCT05352217)
- Testing
- Mobile app ovarian cancer followup (ePRO)
- Where
- 4 sites in Switzerland
- Volunteers
- 7 people
- Sponsor
- Stiftung Swiss Tumor Institute
Breast Neoplasms
Effect of Trastuzumab on Disease Free Survival in Early Stage HER2-Negative Breast Cancer Patients With ERBB2 Expressing Disseminated Tumor Cells
This phase II trial studies the efficacy of trastuzumab treatment in breast cancer patients with stage II-III human epidermal growth factor receptor 2 (HER2)-negative tumors and HER2-expressing bone marrow disseminated tumor…
- Trial name
- NCT01779050
- Testing
- Doxorubicin, Trastuzumab, Cyclophosphamide
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Washington University School of Medicine
Depression, Anxiety
Effects of CBT-Based Intervention Among Patients With Liver Cancer
This study investigates the effects of a CBT- based intervention on depression, anxiety, immune function, quality of life, and overall survival.
- Conditions
- Depression, Anxiety, Liver Cancer, CBT
- Trial name
- NCT05942560
- Testing
- Cognitive behavioural therapy-based intervention, Educational group
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Nethersole School of Nursing
Breast Neoplasms
Exploring Biological Linkage Between Circadian Disruption and Cancer Progression
The purpose of this study is to explore the possible association between the circadian disruption and cancer progression.
- Trial name
- NCT02011815
- Where
- South Korea
- Volunteers
- 236 people
- Sponsor
- Seoul National University Hospital
Lung Cancer
Avoiding Cardiac Toxicity in Lung Cancer Patients Treated With Curative-intent Radiotherapy
Radiotherapy plays a major role in the treatment of lung cancer and recent advances in radiotherapy have led to better cure rates.
- Trial name
- ACCOLADE (NCT03645317)
- Testing
- Blood tests & cardiac imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Prof Corinne Faivre-Finn
Genetic Mutation, MEN1
Overall and Disease Specific Survival in Patients With Confirmed MEN1 With or Without PNET (Pancreatic Neuroendocrine Tumors)
OBJECTIVES: The primary objective of this study is to evaluate the effect of estrogen on the development of the PNET in MEN1 patients.
- Trial name
- NCT03043508
- Testing
- Chart Review, Questionnaire
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Liver Metastases, Colorectal Neoplasms
Multimodal Survival Prediction Model for Colorectal Liver Metastases Post-Operation
The purpose of this study is to construct and validate a multimodal survival prediction model by integrating 3D radiomics features derived from preoperative magnetic resonance imaging (MRI) with systemic clinical baseline…
- Conditions
- Colorectal Liver Metastases, Colorectal Neoplasms, Liver Neoplasms
- Trial name
- NCT07830576
- Testing
- Multimodal Predictive Evaluation
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Anhui Provincial Hospital
Head and Neck Cancer, Survivorship
Survivorship After HNC: A Randomized Controlled Trial Evaluating Patient Care and Adherence to Follow-up
Treatment summary and survivorship care plans (TSSPs) are poorly studied in Head and Neck Cancer (HNC) patients, and given the high frequency of unmet needs, this patient population has potentially the most to benefit from the…
- Trial name
- NCT06127784
- Testing
- Motivational interviewing counselling session
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- Western University, Canada
ALL, Hodgkin Lymphoma
Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer
Survivors of childhood cancer are at greater risk for long-term cognitive impairments that include attention, executive function, intelligence, memory, and processing speed.
- Conditions
- ALL, Hodgkin Lymphoma, Cancer, Survivorship
- Trial name
- NCT05550948
- Testing
- Transcranial photobiomodulation (tPBM) - Mobile System
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- St. Jude Children's Research Hospital
Metastatic Renal Cell Carcinoma ( mRCC)
Immediate Versus Deferred Cytoreductive Nephrectomy With Ipilimumab/Nivolumab in mRCC
The goal of this clinical trial is to learn whether the timing of surgery (cytoreductive nephrectomy) improves outcomes when combined with immunotherapy (ipilimumab and nivolumab) in adults with metastatic clear cell renal cell…
- Trial name
- IVE in mRCC (NCT07233668)
- Testing
- Ipilimumab plus Nivolumab, Cytoreductive Nephrectomy
- Volunteers
- 172 people
- Sponsor
- Seoul National University Hospital
Breast Cancer Survivorship
To Live Better After Breast Cancer Treatment
The most common cancer among women in Sweden is breast cancer. Advances in treatment have improved survival, but these advances have come at a steep price since most treatments impose substantial morbidity and burden on patients…
- Trial name
- NCT06471452
- Testing
- Interaktor
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Tumor Response Rate, Overall Survival
TILA-TACE in Treatment of Hepatocellular Carcinoma
To validate the tumor response rate: in the previous study, the investigators showed that TILA-TACE achieved 100% tumor response rate.
- Trial name
- NCT03910140
- Testing
- TILA-TACE treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cancer Survivorship
Evaluating the Implementation of a Need-Based Cancer Survivorship Program
The project aims to conduct an implementation evaluation of the need-based cancer survivorship program using the RE-AIM framework.
- Trial name
- NCT07830368
- Testing
- Moderate needs intervention, High needs
- Where
- 5 sites in Hong Kong
- Volunteers
- 12,500 people
- Sponsor
- The University of Hong Kong
Pediatric Cancers
Lingzhi for Cancer Children
Ganoderma lucidum (Lingzhi) is a Traditional Chinese Medicine which is widely used as a means to 'strengthen immunity' among patients with cancers.
- Trial name
- NCT00575926
- Testing
- LingZhi capsule
- Where
- 3 sites in Hong Kong
- Volunteers
- 58 people
- Sponsor
- Chinese University of Hong Kong
Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7
Molecular Testing and Imaging in Improving Response in Patients With Stage I-III Triple-Negative Breast Cancer Receiving Chemotherapy MDACC Breast Moonshot Initiative
This clinical trial assesses whether a newly designed algorithm which looks at the genomic signature of each patient's tumor to predict their sensitivity to standard of care treatment verses being placed on a personally designed…
- Conditions
- Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7
- Trial name
- NCT02276443
- Testing
- Chemotherapy, Immunotherapy, Laboratory Biomarker Analysis
- Where
- 5 sites in United States
- Volunteers
- 798 people
- Sponsor
- M.D. Anderson Cancer Center
Event-free Survival, Overall Survival
Transcatheter Intra-arterial Limb Infusion of Cisplatin for Extremity Osteosarcoma
Although there seems to be no benefit from improving the histologic response rate or long-term survival of intra-arterial infusion of cisplatin for localized osteosarcoma of extremities with IOR/OS-3, IOR/OS-5, and COSS 86…
- Conditions
- Event-free Survival, Overall Survival, Local-recurrence Free Survival, Pathological Response
- Trial name
- NCT03909776
- Testing
- Cisplatin
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Peking University People's Hospital
Cervical Cancer
Evaluation of TRANSKRIP ® Plus Chemotherapy in Recurrent-Persistent Cervical Cancer
The purpose of this study is to determine the efficacy and safety the combination of TRANSKRIP ® vs placebo plus Carboplatin/Paclitaxel as first line treatment in patients with recurrent-persistent cervical cancer.
- Trial name
- NCT02446652
- Testing
- Hydralazine/Magnesium, Carboplatin, Paclitaxel
- Where
- Mexico
- Sponsor
- National Institute of Cancerología
Gynecologic Cancer, Gynecologic Neoplasm
The Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology Study
This study compares traditional follow-up of gynaecological cancer patients to an alternative follow-up model. In the alternative follow-up model the patients will meet a nurse at every second consultation.
- Conditions
- Gynecologic Cancer, Gynecologic Neoplasm, Ovarian Cancer, Endometrial Cancer
- Trial name
- LETSGO (NCT04122235)
- Testing
- LETSGO follow-up
- Where
- 12 sites in Norway
- Volunteers
- 755 people
- Sponsor
- Sorlandet Hospital HF
Cancer
Experiencing Transplant With Stories From Survivors
Allograft transplants are offered to people with haematological cancers sometimes as the best chance of a cure. However, the survival rates for these procedures can be quite poor, as the transplant, in itself, can be…
- Trial name
- NCT02349776
- Testing
- Providing testimonies from survivors of transplants to patients
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
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