Clinical trials: Survival , Tumor
Colorectal Cancer, Cytokine-induced Killer Cells
Chemotherapy Combined With CIK Treating Colon Cancer
Cytokine-induced killer cells (CIK) is an auxiliary antitumor treatment. The investigators aim to evaluate the clinical efficacy of chemotherapy combined with CIK in the treatment of postoperative colorectal cancer patients.
- Conditions
- Colorectal Cancer, Cytokine-induced Killer Cells, Postoperative Complications, Survival
- Trial name
- NCT03084809
- Testing
- Cytokine-induced killer cells+ FOLFOX4, FOLFOX4
- Volunteers
- 46 people
- Sponsor
- China Meitan General Hospital
Lung Cancer - Non Small Cell Squamous
Comparison of Longer-term (5 Year+) Outcomes (Survival) of Smokers, Ex-smokers, Never Smoker and Quitters
Between 2010-2020, the LungCAst observational study followed 3700 patients newly diagnosed with lung cancer across 33 hospitals in Wales and England for 2 years to see if smoking status at time of diagnosis predicted survival…
- Trial name
- LungCast2 (NCT07127263)
- Where
- United Kingdom
- Volunteers
- 525 people
- Sponsor
- Hywel Dda Health Board
Colon Adenocarcinoma, MSI Positive Colorectal Cancer
Current Microsatellite Stability Results in Colon Cancer
The goal of this prospective observational study is to learn more about how a specific type of DNA repair issue-called mismatch repair deficiency (dMMR)-affects colon cancer in people living in Turkey.
- Conditions
- Colon Adenocarcinoma, MSI Positive Colorectal Cancer, MSI Negative Colorectal Cancer
- Trial name
- NCT06971107
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1,500 people
- Sponsor
- Turkish Society of Colon and Rectal Surgery
Clear Cell Renal Cell Carcinoma, Prognostic Cancer Model
Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)
This study aims to preoperatively predict DFS of patients with localised ccRCC using a deep learning prognostic model based on enhanced contrast CT images, validate it's predictive ability in multicentre data and compare it's…
- Conditions
- Clear Cell Renal Cell Carcinoma, Prognostic Cancer Model, Recurrent Renal Cell Cancer
- Trial name
- NCT06088134
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Mingzhao Xiao
Colorectal Neoplasms
Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment
The purpose of this study is to evaluate the Progression-Free Survival (PFS) time of Sorafenib in combination with FOLFIRI regimen used as in the second front treatment in patients with advanced CRC after failure of oxaliplatin…
- Trial name
- NCT00839111
- Testing
- sorafenib, FOLFIRI
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Fudan University
Chronic Disease, Kidney Transplantation
Testing the Feasibility of a Self-Management Support Program for Patient With Chronic Diseases in Israel
This study explores an intervention to support people in Israel who are living with chronic health conditions such as cancer or after kidney transplantation.
- Conditions
- Chronic Disease, Kidney Transplantation, Cancer Survivorship
- Trial name
- CDSMP-IL (NCT07367750)
- Testing
- Chronic Disease Self-Management Program (CDSMP)
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- University of Haifa
Neuroendocrine Tumors, Gastroenteropancreatic Neuroendocrine Tumor
Neuroendocrine Tumors - Patient Reported Outcomes
With so many therapeutic options available (i.e.: biologic therapy, liver directed therapy, radiotherapy and chemotherapy), the purpose of this project is to partner with patients on comparative effectiveness research (CER) to…
- Conditions
- Neuroendocrine Tumors, Gastroenteropancreatic Neuroendocrine Tumor, Lung Neuroendocrine Neoplasm, Neuroendocrine Carcinoma
- Trial name
- NET-PRO (NCT05064150)
- Where
- 14 sites in United States
- Volunteers
- 2,539 people
- Sponsor
- University of Iowa
Transcatheter Arterial Chemoembolization, Unresectable Hepatocellular Carcinoma
A Generative Model-based System for Predicting Survival and Guiding Treatment Decisions in Patients With Unresectable Hepatocellularcarcinoma Undergoing Transcatheter Arterial Chemoembolization in Combination With Immunotherapy and Targeted Therapy
The entry point of this study is the proposition of "generative longitudinal prediction," which utilizes only pre-treatment imaging to create high-fidelity predictions of post-treatment imaging.
- Trial name
- NCT07065786
- Testing
- Generative model
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Zhongda Hospital
Insomnia Chronic
Efficacy of Synchronous, Virtual Cognitive Behavioral Therapy for Insomnia Across Phases of Cancer Survivorship
This project is a single center, prospective randomized controlled trial (N=198) primarily evaluating the efficacy of the Survivorship Sleep Program vs. Enhanced Usual Care on insomnia severity among cancer survivors.
- Trial name
- NCT06807086
- Testing
- Cognitive Behavioral Therapy - Insomnia, Enhanced Usual Care
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Massachusetts General Hospital
Adrenocortical Carcinoma
Sorafenib Plus Paclitaxel in Adreno-Cortical-Cancer Patients
The study is designed as a Phase II, prospective, non randomized, open-label, single arm, multicenter trial, in which patients with locally advanced or metastatic ACC not amenable to complete surgical resection and progressing to…
- Trial name
- PAXO (NCT00786110)
- Testing
- Sorafenib, Paclitaxel
- Where
- 5 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Breast Cancer, Lymphoma
Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS)
This study aims to evaluate the prevalence, biological mechanism and survivorship impact of cognitive toxicity among adolescent and young adult (AYA) patients diagnosed with curable cancers.
- Conditions
- Breast Cancer, Lymphoma, Germ Cell Tumor, Cognitive Impairment
- Trial name
- NCT03476070
- Where
- 3 sites in Singapore
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Prostate Cancer
Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy
This is a prospective study to determine if the adjuvant use of Curcumin improves recurrence-free survival.
- Trial name
- NCT02064673
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- yair lotan
Pancreatic Neuroendocrine Tumor
Pancreatic Neuroendocrine Tumor:Factor of Surgery Influencing Survival
Investigator determined the factor of surgery associated with the survival of pancreatic neuroendocrine tumor.
- Trial name
- NCT02624154
- Testing
- pancreatectomy
- Volunteers
- 2 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Thrombosis, Venous
Effects Of Nadroparin In Patients With Lung, Pancreas Or Prostate Cancer
This study will evaluate the effects of nadroparin on survival and disease progression in patients with hormone-refractory prostate cancer (HRPC), locally advanced pancreatic cancer or non-small-cell lung carcinoma (NSCLC).
- Trial name
- NCT00312013
- Testing
- Nadroparin
- Where
- 95 sites in Belgium, Canada and 9 more
- Volunteers
- 503 people
- Sponsor
- GlaxoSmithKline
Breast Cancer
Narrative Visualization for Breast Cancer Survivors' Physical Activity
This study tests the feasibility and acceptability of a physical activity intervention that combines use of a wearable activity monitor with a scrapbook.
- Trial name
- NCT03612596
- Testing
- Narrative visualization, Standard self-regulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Gastric Cancer, Recurrence
Survival Rates and Quality of Life According to Follow-up Period After Gastrectomy for Gastric Cancer (STOFOLUP)
This study is a multi-center, prospective, randomized controlled study. The aim of this study is to compare survival rates and to observe quality of life and nutritional status according to follow-up period in patients who…
- Conditions
- Gastric Cancer, Recurrence, Quality of Life
- Trial name
- NCT04740346
- Testing
- Computed tomography, Chest X-ray, and blood test
- Where
- 16 sites in South Korea
- Volunteers
- 886 people
- Sponsor
- National Cancer Center, Korea
Breast Neoplasm
Post-treatment Care of Breast Cancer Survivors
The overall goal of this proposal is to improve the post-treatment care of breast cancer survivors and to understand the barriers to optimal post-treatment care in Latina and Non-Hispanic women.
- Trial name
- NCT00821288
- Testing
- Survivorship Intervention, Facing Forward
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Columbia University
Cancer
Improving Cancer Survival and Reducing Treatment Variations With Protocols for Emergency Care
Significant challenges and gaps remain in navigating transitions between acute care and outpatient care for many cancer survivors.
- Trial name
- ICARE (NCT04673890)
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Illinois Chicago
Breast Cancer
The Young Women's Breast Cancer Study
The investigators are conducting a longitudinal cohort study of young women with breast cancer. The investigators identify women age 40 and younger with newly-diagnosed breast cancer from academic and community healthcare…
- Trial name
- HOHO (NCT01468246)
- Where
- 13 sites in United States, Canada
- Volunteers
- 1,302 people
- Sponsor
- Dana-Farber Cancer Institute
Hepatocellular Carcinoma, Hepatitis B Virus
Effects of Antiviral Therapy on Patients With HBV-related HCC
Based on the follow-up data of patients who underwent hepatectomy for HBV-related HCC at the First Affiliated Hospital of Xi'an Jiaotong University.
- Conditions
- Hepatocellular Carcinoma, Hepatitis B Virus, Survival
- Trial name
- NCT05406089
- Testing
- Medication history
- Volunteers
- 494 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
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