Clinical trials: Survival , Tumor
Prostate Cancer
PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness
PROMISE aims to create a comprehensive nationwide registry of prostate cancer patients with germline pathogenic variants by prospectively screening approximately 5,000 subjects with a confirmed prostate cancer diagnosis, either…
- Trial name
- NCT04995198
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Prostate Cancer Clinical Trials Consortium
Cancer Metastatic, Symptoms and Signs
Symptom Management and Survivorship Plus Coaching for Advanced Cancer Survivors and Their Caregivers
The protocol will include a 10-week Symptom Management and Survivorship Handbook (SMSH) intervention to address informational needs for the management of physical and psychological symptoms, bundled with telephone delivered…
- Conditions
- Cancer Metastatic, Symptoms and Signs, Quality of Life
- Trial name
- SMSH and SMSH+ (NCT07415564)
- Testing
- Symptom Management and Survivorship Handbook + Coaching, Symptom Management and Survivorship Handbook
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Arizona
Non Small Cell Lung Cancer NSCLC
Study of Durvalumab + Tremelimumab With Chemotherapy or Durvalumab With Chemotherapy or Chemotherapy Alone for Patients With Lung Cancer (POSEIDON).
This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of durvalumab + tremelimumab combination therapy + Standard of care (SoC) chemotherapy or durvalumab monotherapy + SoC…
- Trial name
- POSEIDON (NCT03164616)
- Testing
- Durvalumab, Tremelimumab, Abraxane + carboplatin
- Where
- 175 sites in United States, Brazil and 17 more
- Volunteers
- 1,186 people
- Sponsor
- AstraZeneca
Prostate Cancer, Biochemical Recurrence
Salvage Hypofractionated Accelerated Versus Standard Radiotherapy for Biochemical Failure After Prostatectomy
Patients with a biochemical recurrence after radical prostatectomy for moderate- or high- risk prostate cancer are randomly assigned to hypofractionated, accelerated high dose radiation therapy group (65 Gy, 26 fractions) and a…
- Conditions
- Prostate Cancer, Biochemical Recurrence, Radiation, Hypofractionation
- Trial name
- SHARE (NCT03920033)
- Testing
- Salvage radiation therapy
- Where
- 2 sites in South Korea
- Volunteers
- 288 people
- Sponsor
- Asan Medical Center
Neoplasms
Cancer Survival in Reunion Island , 1998-2008 (SUCRE)
Cancer survival is important to determine prognostic of patients and evaluate care and prevention health strategies. Sucre is the first study to describe cancer survival in Reunion Island.
- Trial name
- SUCRE (NCT02900287)
- Where
- Reunion
- Volunteers
- 18,000 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
HER2 Low Breast Carcinoma
Tumor Characteristics and Survival Rate of HER2-Low Breast Cancer Patients
In this large-scale cross-sectional study, we evaluated disease-free survival (DFS), overall survival (OS), and clinicopathological characteristics of BC patients from 1991 to 2022, retrospectively.
- Trial name
- NCT05754047
- Testing
- immunohistochemistry (IHC) and in situ hybridization (ISH) Test
- Volunteers
- 3,582 people
- Sponsor
- Mahdis Bayat
Cancer
The Move for Your Health Pilot Study
The Move for Your Health Pilot Study is a 16-week study in older cancer survivors to replace and break-up sedentary activity with short bouts of light physical activity.
- Trial name
- NCT03632694
- Testing
- Health Coaching and Tech Support, Tech Support Only
- Volunteers
- 54 people
- Sponsor
- Cindy Blair, PhD, MPH
Primary Hepatocellular Carcinoma, Unresectable Liver Cancer
A Trial of Behavioral Intervention on Prognostic Survival of Patients With Unresectable Liver Cancer
Research purpose 1. To evaluate the impact of complex behavioral intervention on the one-year overall survival rate of patients with unresectable liver cancer after comprehensive treatment, a comparative study was conducted…
- Trial name
- NCT07337031
- Testing
- complex behavioral intervention
- Where
- China
- Volunteers
- 193 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Ovarian Cancer
Ancillary Study GOG 158: Survival Analysis Based on Reclassification to a Two-Tier Grading System
Primary Objective: To reclassify the histologic grade of the serous ovarian cancer specimens of patients enrolled on Gynecologic Oncology Group (GOG) protocol 158 using a two-tier system.
- Trial name
- NCT00837993
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Survivorship
Study of a Support Program for Quality of Life in Chinese Cancer Patients and Survivors
The purpose of this study is to evaluate different combinations of cancer education sessions, counseling sessions, and peer support meetings developed for Chinese cancer patients and survivors.
- Trial name
- NCT07454330
- Testing
- Cancer Education, Meaning-Centered Counseling, Peer Support
- Where
- 7 sites in United States
- Volunteers
- 64 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Neoplasms, Treatment
Classified Treatment Strategy for De-novo Metastatic Breast Cancer After Systemic Adjuvant Therapy
For patients with de novo stage IV breast cancer, the current debate is whether local surgery can improve the survival of patients.
- Conditions
- Breast Neoplasms, Treatment, Metastatic Breast Cancer, Survival
- Trial name
- CS (NCT05285332)
- Testing
- surgical treatment 1, surgical treatment 2, Systemic therapy
- Volunteers
- 362 people
- Sponsor
- Changhai Hospital
Colorectal Cancer, Chinese Herbal Medicine
Clinical Study on the Effect of Brucea Javanica Oil Emulsion Injection on the Survival of Patients With Advanced Colorectal Cancer Who Failed to Receive Multi-line Treatment
The purpose of the study is to evaluate the safety and effectiveness of Brucea javanica oil emulsion injection in patients with advanced colorectal cancer who failed to undergo multi-line treatment
- Conditions
- Colorectal Cancer, Chinese Herbal Medicine, Progression-free Survival, Quality of Life
- Trial name
- NCT05897749
- Testing
- Brucea javanica oil emulsion injection, The best supportive treatment
- Where
- 4 sites in China
- Volunteers
- 60 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Breast Cancer Survivorship, Muscle Oxygenation
Muscle Oxygen Saturation and Functional Capacity in Breast Cancer Survivors
This cross-sectional observational study aims to assess muscle oxygen saturation (SmO2) in the intercostal, quadriceps, and triceps surae muscles using near-infrared spectroscopy (NIRS) during functional exercise tests in breast…
- Conditions
- Breast Cancer Survivorship, Muscle Oxygenation, Near-infrared Spectroscopy, Exercise
- Trial name
- NCT06976593
- Testing
- Functional Exercise Testing and Muscle Oxygen Saturation Measurement
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Extremadura
Metastatic Colorectal Cancer
AlloStim® In-Situ Vaccine in Pre-Treated Metastatic Colorectal Cancer
This is a personalized anti-cancer vaccine protocol which includes an in-situ (in the body) cancer vaccine step which combines killing a single metastatic tumor lesion by use of cryoablation in order to cause the release of…
- Trial name
- NCT01741038
- Testing
- AlloStim®, cryoablation, Physician's Choice (PC)
- Where
- Thailand
- Sponsor
- Mirror Biologics, Inc.
Cancer, Nutrition, Healthy
Physical Activity and Nutrition in Cancer Survivors
This study aims to investigate the independent and combined associations between physical activity and nutrition condition with mortality among cancer survivors.
- Conditions
- Cancer, Nutrition, Healthy, Physical Inactivity
- Trial name
- NCT06350214
- Testing
- physical activity and nutrition assessment
- Volunteers
- 3,100 people
- Sponsor
- West China Hospital
Breast Cancer
Safety of Pregnancy in BRCA Mutated Breast Cancer Patients
The present study aims at refining the understanding of the effect of pregnancy on breast cancer outcomes in the specific population of BRCA mutated patients with known history of breast cancer.
- Trial name
- NCT03673306
- Testing
- Clinical outcomes
- Where
- 81 sites in United States, Argentina and 24 more
- Volunteers
- 4,732 people
- Sponsor
- Jules Bordet Institute
Cancer Survivorship, Sexual Function Disturbances
Sexual Health and Rehabilitation Online (SHAREonline)
SHAREonline is a study for young female cancer survivors that are experiencing changes in sexual health and function. The purpose of this research is to compare two brief interventions delivered by videoconference to learn if…
- Trial name
- NCT06458049
- Testing
- Group Session, Coaching Call, Educational Materials
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Dana-Farber Cancer Institute
Myeloid Leukemia
Genome-wide Pharmacogenetic Candidate Gene Single Nucleotide Polymorphism (SNP) Array-based Approach to Predict Chemoresponse and Survival in Patients With Acute Myeloid Leukemia With Normal Karyotype
The most reliable prognostic marker of acute myeloid leukemia(AML) is cytogenetics by karyotyping. According to cytogenetic results, the patients with AML are classified as better, intermediate and poor prognosis groups.
- Trial name
- NCT01066338
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Breast Cancer
The Role of Diet and Lifestyle in Breast Cancer Survival
Diet has been found to influence hormone production and metabolism which in turn could affect the incidence of hormone related cancers.
- Trial name
- DietCompLyf (NCT00701584)
- Where
- United Kingdom
- Volunteers
- 3,390 people
- Sponsor
- University College London Hospitals
Gastric (Stomach) Cancer, Biological Therapy
The Safety and Clinical Efficacy of RAK Cell Therapy in Late-stage Gastric Cancer: A Randomized Controlled Trial
This project employs a prospective, double-blind, randomized controlled trial methodology to comparatively analyze the safety and survival outcomes of human umbilical cord blood RAK cells applied in advanced gastric cancer.
- Conditions
- Gastric (Stomach) Cancer, Biological Therapy, Immunotherapy
- Trial name
- RAK in GC (NCT07212933)
- Testing
- RetroNectin active Killer cells, TAS-102 (trifluridine and tipiracil, Lonsurf®)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese PLA General Hospital
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