Clinical trials: Survival , Tumor
Rectal Cancer, Organ-Space Surgical Site Infection
Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery
In rectal cancer surgery, the organ/space surgical site infection (O/S-SSI) has an impact on patient's prognosis. Its influence in the oncologic outcomes remains controversial.
- Trial name
- VINCat_PDO_2 (NCT06382415)
- Where
- Spain
- Volunteers
- 3,826 people
- Sponsor
- Hospital de Granollers
Lung Cancer
Monoclonal Antibody Therapy Plus BCG in Treating Patients With Limited-Stage Small Cell Lung Cancer
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. BCG may activate the immune system to kill tumor cells.
- Trial name
- NCT00006352
- Testing
- BCG vaccine, monoclonal antibody BEC2
- Where
- Netherlands
- Volunteers
- 453 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Gastrointestinal Stromal Tumor
Evaluation of Nilotinib In Patients With Advanced Gastrointestinal Stromal Tumor (GIST)
This study will assess time-to-disease progression in patients with advanced gastrointestinal stromal tumor (GIST) previously treated with imatinib ≥600 mg.
- Trial name
- NCT01110668
- Testing
- Nilotinib
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Novartis Pharmaceuticals
Metastatic Renal Cell Carcinoma
A Retrospective Real World Analysis Of Sutent In Patients With Metastatic Renal Cell Carcinoma In Community And Academic Centers To Assess The Impact Of Dose Variation On Duration Of Response And Overall Survival
This is a retrospective, non-interventional study which looks at the cohort of Renal Cell Carcinoma patients in a real life clinical setting and analyses into factors why these patients have been surviving for as long as 3-5…
- Trial name
- NCT01917214
- Testing
- Sutent: Observational Study
- Volunteers
- 212 people
- Sponsor
- Pfizer
Childhood Cancer Survivors
Virtual Health Insurance Navigation Pilot Program for Childhood Survivors (HINTII)
The investigators are conducting a Type I hybrid effectiveness-implementation trial to assess the effectiveness of HINT-S (synchronous) compared to enhanced usual care (EUC) in promoting health insurance literacy, thus reducing…
- Trial name
- HINTII (NCT05527392)
- Testing
- Health Insurance Navigation Tools Program
- Where
- United States
- Volunteers
- 529 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer Survivors
Cancer Survival Through Weight Loss and Exercise
To test the effectiveness and feasibility of intensive motivational, behavior modifying intervention aimed at improving physical activity and dietary habits to produce at least 7% weight loss in women with a history of breast…
- Trial name
- CASTLE (NCT01217216)
- Testing
- Group-based Intervention, Telephone-based Intervention
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Pennington Biomedical Research Center
Pancreatic Cancer, Cancer Cachexia
Florida Pancreas Collaborative Next Generation Biobank
The goal of this study is to partner with individuals known or suspected to have pancreatic cancer to build a biobank dedicated to minimizing disparities and personalizing care for individuals affected by pancreatic cancer.
- Trial name
- NCT03851133
- Testing
- Blood Sample Collection, Tumor Sample collection, Data Collection
- Where
- 14 sites in United States
- Volunteers
- 500 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Cancer Survivor, Depression
INSPIRE: Internet and Social-media Program With Information and Resources for Long-Term Cancer Survivors Who Underwent Stem Cell Transplant
This randomized clinical trial studies an internet and social-media program for improving quality of life in long-term survivors who underwent stem cell transplant.
- Conditions
- Cancer Survivor, Depression, Hematopoietic and Lymphoid Cell Neoplasm, Myelodysplastic Syndrome
- Trial name
- INSPIRE (NCT01602211)
- Testing
- Internet-Based Intervention, Medical Chart Review, Quality-of-Life Assessment
- Where
- 6 sites in United States
- Volunteers
- 1,600 people
- Sponsor
- Fred Hutchinson Cancer Center
Frailty, Survivorship
Remote Exercise Video Adaptations to Maximize Physical Activity in Childhood Cancer
The goal of this observational study is to leverage childhood cancer survivor input to adapt video content of a digital video disc-(DVD) delivered evidence-based PA intervention, originally designed for community-dwelling older…
- Conditions
- Frailty, Survivorship, Childhood Cancer
- Trial name
- NCT06411704
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St. Jude Children's Research Hospital
Recurrence, Metastasis
Prognostic Value of CTC in HNSCC Patients
We hypothesized that the number of circulating tumor cells (CTCs) and molecular markers on CTCs could be a prognostic factor or predictive factor to patients with head neck cancer.
- Conditions
- Recurrence, Metastasis, Death
- Trial name
- CTCHNSCC01 (NCT01884129)
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Survivorship, Cancer
Physical Activity Counselling for Young Adult Cancer Survivors
Survival rates for cancer are increasing, resulting in more young adult cancer survivors living with lingering side effects. Physical activity has been shown to improve the quality and length of life in young adult cancer…
- Trial name
- NCT04163042
- Testing
- 12-week videoconferencing behavioural support intervention to promote physical activity behaviour
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Ottawa
Endometrial Cancer
Comparison of Five-year Survival and Disease-free Survival in Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With and Without Uterine Manipulator
Comparison of five-year survival and disease-free survival in patients diagnosed with endometrium cancer who underwent total laparoscopic hysterectomy with and without a uterine manipulator
- Trial name
- NCT06307886
- Testing
- Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With manipulator, lPatients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy without uterine manipulator
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Anaplastic Large Cell Lymphoma, ALK-Negative, Follicular Helper T-Cell Lymphoma
Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy
This phase III trial compares the effect of high dose chemotherapy and the patients' own (autologous) stem cells to observation only in patients with peripheral T-cell lymphoma who achieved a complete response after initial…
- Conditions
- Anaplastic Large Cell Lymphoma, ALK-Negative, Follicular Helper T-Cell Lymphoma, Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type, Peripheral T-Cell Lymphoma, Not Otherwise Specified
- Trial name
- NCT06724237
- Testing
- Autologous Hematopoietic Stem Cell Transplantation, Best Practice, Biospecimen Collection
- Where
- 165 sites in United States, Mexico
- Volunteers
- 294 people
- Sponsor
- Eastern Cooperative Oncology Group
Obesity, Childhood, Cancer
NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors
Pediatric cancer survivors are at an increased risk of excessive weight gain and reduced exercise behaviors with the potential for this risk to worsen over time.
- Conditions
- Obesity, Childhood, Cancer, Survivorship
- Trial name
- NOURISH-T+ (NCT04656496)
- Testing
- NOURISH-T+, Brief NOURISH-T+
- Where
- 10 sites in United States
- Volunteers
- 520 people
- Sponsor
- University of South Florida
Esophageal Cancer
Low-dose Aspirin Therapy for Esophageal Cancer
The aim of this study is to evaluate the survival benefit of low-dose aspirin use for stage II-III esophageal cancer patients.
- Trial name
- NCT02326779
- Testing
- Acetylsalicylic acid
- Sponsor
- Zhejiang University
Nasopharyngeal Carcinoma, Metastasis
Platinum Plus Low-dose Long-term Continuous Intravenous Infused 5-Fluorouracil in Metastatic Nasopharyngeal Carcinoma
The treatment of distant metastasis is a key challenge for nasopharyngeal carcinoma because of poor outcomes, among which, chemotherapy is the cornerstone.
- Conditions
- Nasopharyngeal Carcinoma, Metastasis, Chemotherapy, Survival
- Trial name
- NCT04472403
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-sen University
Survivorship, Breast Cancer
The LYSA (Linking You to Support and Advice) Trial
This study's aim is to evaluate the feasibility of introducing a women's malignancy survivorship clinic incorporating symptom management through ePRO collection (complex intervention) into routine follow up care in patients with…
- Conditions
- Survivorship, Breast Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LYSA (NCT05035173)
- Testing
- Survivorship Clinic Assessments, Survivorship Clinic Nurse Resource, Survivorship Clinic Dietitian Resource
- Where
- Ireland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College Cork
Neoplasms
Vitamin D Levels and Survival in Cancer Patients
Using the population-based data sources in Iceland and the well-characterized AGES-Reykjavik cohort, our overarching aims are on exploring whether pre-diagnostic serum levels of 25-hydroxyvitamin D (25(OH)D) among older…
- Trial name
- NCT03266887
- Volunteers
- 5,764 people
- Sponsor
- Icelandic Heart Association
Cancer, Nutrition, Healthy
Physical Activity and Nutrition in Cancer Survivors
This study aims to investigate the independent and combined associations between physical activity and nutrition condition with mortality among cancer survivors.
- Conditions
- Cancer, Nutrition, Healthy, Physical Inactivity
- Trial name
- NCT06350214
- Testing
- physical activity and nutrition assessment
- Volunteers
- 3,100 people
- Sponsor
- West China Hospital
Hypopituitarism, Radiotherapy-Induced Hypopituitarism
Improving Survivorship and Health-related Quality of Life in Patients With Primary Brain Tumours
Background: Approximately 480 primary, non-pituitary, brain tumours were diagnosed in Ireland each year between 1994 and 2013. Recent developments in treatment have greatly improved survival for younger patients in the 15-54 age…
- Conditions
- Hypopituitarism, Radiotherapy-Induced Hypopituitarism, Brain Tumor
- Trial name
- NCT06014398
- Testing
- Dynamic testing of Pituitary Function
- Where
- 2 sites in Ireland
- Volunteers
- 50 people
- Sponsor
- Royal College of Surgeons, Ireland
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