Clinical trials: Survival Rate
Platinum-resistant Recurrent Ovarian Cancer, Fallopian Tube Cancers
Liposomal Irinotecan Plus Enlonstobart for Platinum-Resistant Recurrent Ovarian Cancer
This is a prospective, single-center, single-arm exploratory clinical study designed to evaluate the efficacy and safety of liposomal irinotecan combined with enlonstobart in patients with platinum-resistant recurrent ovarian…
- Conditions
- Platinum-resistant Recurrent Ovarian Cancer, Fallopian Tube Cancers, Epithelial Ovarian Cancer, Primary Peritoneal Cancer
- Trial name
- NCT07591831
- Testing
- Liposomal Irinotecan
- Volunteers
- 30 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Relapsed/Refractory Multiple Myeloma
Belantamab Mafodotin, Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma
Evaluate the efficacy and safety of Belantamab Mafodotin, cyclophosphamide, and dexamethasone in patients with Relapsed/Refractory Multiple Myeloma
- Trial name
- NCT04896658
- Testing
- Belantamab Mafodotin, Cyclophosphamide and Dexamethasone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Infertility
Closed Vitrification of Oocytes
This study is aimed to evaluate the use of a closed device for storage of vitrified oocytes.
- Trial name
- NCT01745536
- Testing
- Oocytes are vitrified/stored using a closed device, Oocytes are vitrified/stored using an open device
- Where
- 2 sites in Spain
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Colorectal Neoplasms
Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment
The purpose of this study is to evaluate the Progression-Free Survival (PFS) time of Sorafenib in combination with FOLFIRI regimen used as in the second front treatment in patients with advanced CRC after failure of oxaliplatin…
- Trial name
- NCT00839111
- Testing
- sorafenib, FOLFIRI
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Fudan University
Gastric Cancer
A Study of Capecitabine [Xeloda] in Combination With Trastuzumab [Herceptin] and Oxaliplatine in Patients With Resectable Gastric Cancer
This study will evaluate the disease free survival rate of a combination of capecitabine [Xeloda] and oxaliplatin (XELOX) with trastuzumab [Herceptin] in patients with resectable gastric cancer.
- Trial name
- NCT01130337
- Testing
- Capecitabine [Xeloda], Oxaliplatin, Trastuzumab [Herceptin]
- Where
- 30 sites in Spain
- Volunteers
- 36 people
- Sponsor
- Hoffmann-La Roche
Dental Malocclusion
Eighteen-month Orthodontic Bracket Survival Rate With the Conventional Bonding Technique Versus RMGIC and V-prep
The aim of this study was to evaluate over eighteen months the clinical bonding failure and survival rates of the conventional bonding technique using the Transbond XT (3M Unitek, Monrovia, California, USA) and the RMGIC Fuji…
- Trial name
- NCT05939102
- Testing
- v-prep combined with RMGIC for bracket bonding, Conventional bracket bonding technique
- Where
- Lebanon
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Rectal Cancer
Randomized Clinical Trial on Preoperative Radiotherapy 25 Gy in Rectal Cancer
The purpose of this study is to establish the influence of time-interval between preoperative hyperfractionated radiotherapy (5x5 Gy) and surgery on long term overall survival (5 years), local and distant recurrence rate…
- Trial name
- NCT01444495
- Testing
- Preoperative radiotherapy, Surgery
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Jagiellonian University
Other Disorders of Soft Tissues
Endostar Combined With AI Regimen Compared With AI in Adjuvant Treatment
To evaluate the effectiveness, safety and tolerability of Endostar (recombinant human endostatin) combined with AI chemotherapy in adjuvant treatment after radical resection of recurrent soft tissue sarcoma.
- Trial name
- NCT04699214
- Testing
- Endostar (recombinant human endostatin injection), Chemotherapy AI
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Yong Chen
Dental Restoration, Dental Implant
Prosthetic Outcomes and Clinical Performance of Implant Supported Zirconia Crowns
To compare biological, technical, radiographic, and patient-reported outcomes of two types of monolithic zirconia crowns screw-retained to implant.
- Trial name
- NCT06417632
- Testing
- Graded Zirconia Crown, Conventional Zirconia Crown
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Dental Implant Survival Rate
Survival Rate of Dental Implants Placed in Sinus Lift Performed With Two Different Grafts
Previous in a randomized way, it will be performance 12 bilateral sinus lift with autologous bone in one side and the in other with xenograft material.
- Trial name
- NCT01836744
- Testing
- Survival rate dental implant (OsseoSpeed™)
- Where
- Portugal
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Grupo de Investigação: Cirurgia Oral, Peridontologia, Implantologia
Colorectal Cancer
Comparing HAI-90Y (SIR-spheres)+Chemotx LV5FU2 Versus Chemotx LV5FU2 Alone to Treat Colorectal Cancer
The investigators propose to conduct a randomised phase III trial evaluating a maintenance strategy comparing hepatic arterial injection of Yttrium-90 resin microspheres plus continuing simplified chemotherapy with/without…
- Trial name
- NCT01895257
- Testing
- HAI-90Y radioembolization (SIR-spheres injection), systemic chemotherapy LV5FU2
- Where
- 10 sites in Belgium
- Volunteers
- 162 people
- Sponsor
- Universiteit Antwerpen
HER2 Low Breast Carcinoma
Tumor Characteristics and Survival Rate of HER2-Low Breast Cancer Patients
In this large-scale cross-sectional study, we evaluated disease-free survival (DFS), overall survival (OS), and clinicopathological characteristics of BC patients from 1991 to 2022, retrospectively.
- Trial name
- NCT05754047
- Testing
- immunohistochemistry (IHC) and in situ hybridization (ISH) Test
- Volunteers
- 3,582 people
- Sponsor
- Mahdis Bayat
Malfunction; Catheter, Thrombosis
Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA
Surface thrombogenicity of standard double lumen catheters (stDLC) and surface modified film-coated domain structured double lumen catheters (fcDLC) consisting of a novel reactive polyurethane copolymer coating showed that in…
- Conditions
- Malfunction; Catheter, Thrombosis, Mechanical Complication of Hemodialysis Catheter
- Trial name
- PROCOPrt-PA (NCT01670474)
- Testing
- rt-PA (2mg/2mL) actilysis, rt-PA
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Centre Hospitalier du Centre du Valais
Relapsed and Refractory Multiple Myeloma (RRMM)
Real-World Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma
Primary Objective: 1. To describe the distribution of treatment regimens and objective response rate (ORR) in a Benchmark Cohort of real-world patients with relapsed/refractory multiple myeloma (RRMM) who initiate treatment after…
- Trial name
- NCT05673967
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Regeneron Pharmaceuticals
Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection
Impact of Nurses' Behavior Change and Evidence-Based Practice Implementation on Quality Indicators in Intensive Care Units in Low- and Middle-Income Countries
Study title: Impact of nurses' behavior change and implementing evidence-based practice to improve quality indicators in intensive care units in low-and middle-income countries Background and Rationale: Quality care is crucial…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection, Pressure Ulcers (Hospital-acquired Pressure Injuries), Prolonged Intensive Care Unit Length of Stay
- Trial name
- NCT07397364
- Testing
- Evidence based practices bundles of care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pulmonary Adenocarcinoma
The Impact of Polynuclear Neutrophils' Intra-tumoral Rate and the Mutational Status in Pulmonary Adenocarcinomas on Survival
Lung cancer is one of the most frequent cancer concerning human beings and it represents, worldwide, one of the first cause of death.
- Trial name
- NCT04761640
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Locally Advanced Rectal Cancer (LARC), MSS (Microsatellite Stable)
SCRT Based iTNT vs. LCRT Based TNT for MSS Locally Advanced Rectal Cancer
In this prospective, multicentre, randomized phase III trial, 612 locally advanced rectal cancer (LARC, T3-4/N+M0) patients with at least one high-risk features (lower location (≤5cm), cT4, cN2, MRF+, EMVI+, TD+) will be…
- Trial name
- TORCH-STAR (NCT07551479)
- Testing
- short-course radiaotherapy, long-course chemoradiaothearpy, Capecitabine
- Where
- China
- Volunteers
- 612 people
- Sponsor
- Fudan University
Implant Clinical Survival, Dental Implant Bone Loss
A Multi-center Study to Evaluate Bone Loss, Survival Rate and Stability of ICE Implant
The current prospective clinical study's aim is to determine ABT's ICE implant survival rate, crestal interproximal bone resorption during 24 months post implant insertion and to assimilate the drilling sequence during the…
- Trial name
- ICE (NCT01960361)
- Testing
- ICE dental implant
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Alpha - Bio Tec Ltd.
Acute Liver Failure
Registry Protocol for Tracking Trial Subjects After VTI-206 Study Completion
VTI-207 (NCT01452295) is designed to follow subjects, both treated and control, for five years after their completion of study participation in protocol VTI-206 (NCT00973817) to gather information relating to the incidence of…
- Trial name
- NCT01452295
- Testing
- ELAD (Extracorporeal Liver Assist System)
- Sponsor
- Vital Therapies, Inc.
Dental Restoration Failures
An In-vivo Survival Rate of Different Onlay Materials Placed Over Endodontically Treated Molar Teeth
This study aims to evaluate the survival rates of onlays placed over posterior endodontically treated teeth restored with zirconia, lithium disilicate and lithium disilicate reinforced with zirconia.
- Trial name
- NCT07753941
- Testing
- Monolithic zirconia partial coverage onlays, Lithium disilicate partial coverage onlays, zirconia-reinforced lithium disilicate partial coverage onlays
- Where
- Jordan
- Volunteers
- 39 people
- Sponsor
- Yousef Mahmoud Salem