Clinical trials: Survivors of Childhood Cancer, active
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Testing Counseling and Mobile Health Interventions to Improve Physical Activity and Diet Quality in Survivors of Childhood Cancer
This clinical trial evaluates several behavioral interventions for the improvement of physical activity in cancer patients. Childhood and adolescent/young adult cancer survivors have been reported to have poor diet quality and…
- Trial name
- SALSA (NCT05075759)
- Testing
- Behavioral Intervention, Survey Administration, Interview
- Where
- 2 sites in United States
- Volunteers
- 374 people
- Sponsor
- Fred Hutchinson Cancer Center
Anthracycline Related Cardiotoxicity in Childhood Cancers, Chemotherapeutic Toxicity
Evaluation of Cardiac and Endothelial Function in Children and Adolescents Treated With Anthracycline
In recent decades, the survival rate of children with cancer has increased significantly thanks to personalized treatments and the adoption of international therapeutic protocols.
- Conditions
- Anthracycline Related Cardiotoxicity in Childhood Cancers, Chemotherapeutic Toxicity, Childhood Cancer Survivors
- Trial name
- CARDIO-PED (NCT07253077)
- Testing
- Biomarker detection
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Survivors of Childhood Cancer, Alopecia
A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors
This study will test whether minoxidil taken by mouth (oral minoxidil) can improve hair loss caused by cancer treatment in children and young adults.
- Trial name
- NCT05778825
- Testing
- Oral Minoxidil
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Acute Leukemia, Acute Lymphoblastic Leukemia
A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors
This clinical trial evaluates a high intensity electronic health (eHealth) intervention program for reducing learning disparities in children with cancer.
- Conditions
- Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Lymphoblastic Lymphoma
- Trial name
- NCT05428176
- Testing
- Best Practice, Internet-Based Intervention, Quality-of-Life Assessment
- Where
- 4 sites in United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Pediatric Cancer
Food is Medicine in Survivorship: Examining the Feasibility and Impact of a Scalable Food Delivery and Culinary Medicine Program (FoodiiS) Among Pediatric Cancer Survivors and Their Families
The goal of this research study is to learn if the FoodiiS-Kids intervention is useful to parents and guardians of pediatric cancer survivors.
- Trial name
- NCT07218328
- Testing
- FoodiiS plus Culinary Essentials Food Delivery, Culinary Essentials Food Delivery Only, Waitlist control
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
This clinical trial tests the impact of a culturally-tailored home-based physical activity program on physical fitness in Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors.
- Trial name
- NCT06410209
- Testing
- Discussion, Goal Setting, Interview
- Where
- 77 sites in United States, Puerto Rico
- Volunteers
- 190 people
- Sponsor
- Children's Oncology Group
Survivors of Childhood Cancer
Behavioral Reinforcement Intervention for Greater Health Trajectories After Childhood Cancer (BRIGHT)
Survivors of childhood cancer have a substantially increased risk of long-term health problems in adulthood, including cardiovascular disease, metabolic disorders, psychological morbidity, and impaired health-related quality of…
- Trial name
- BRIGHT (NCT07384286)
- Testing
- Lifestyle Management
- Where
- Sweden
- Volunteers
- 900 people
- Sponsor
- Vastra Gotaland Region
Survivors of Childhood Cancer
Complementary Behavioral Interventions To Remediate Cognitive Impairment or Emotional Distress in Cancer Survivors
Childhood cancer survivors are at risk for accelerated aging due to the specific treatments they have received to cure their cancer.
- Trial name
- COPILOT (NCT06989463)
- Testing
- 12 Week Exercise Intervention, Cognitive Training Intervention, Mindfulness practice intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Jude Children's Research Hospital
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors
The clinical trial compares the reproducibility and accuracy of cardiac tonometry-based portable systems that may detect early cardiac dysfunction (SphygmoCor® Xcel and Oscar 2™ ambulatory blood pressure monitor) at home and in…
- Trial name
- NCT05138991
- Testing
- Echocardiogram Recording, Questionnaire Administration, Stress Cardiac Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Childhood Cancer, Survivorship
A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship
More than 80% of childhood cancer survivors develop serious or life-threatening late effects after cancer therapy, but <20% receive recommended survivorship care offered at cancer center survivorship clinics.
- Conditions
- Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice
- Trial name
- BRIDGES (NCT05448560)
- Testing
- Multi-level Intervention of shared model of survivorship care, Comparison Group
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- Georgetown University
Childhood Cancer, Childhood Cancer Survivors
Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors
The goal of the Cardiovascular Health Equity Through Food (CHEF) program is to make it easier for participants and families to cook and eat healthy foods during and following childhood cancer treatment with the long-term goal of…
- Trial name
- CHEF (NCT06609473)
- Testing
- CHEF Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Dana-Farber Cancer Institute
Childhood Non-Hodgkin Lymphoma, Childhood Acute Lymphoblastic Leukemia
Goal Management Training for Adult Survivors of Childhood Leukemia and Non-Hodgkins Lymphoma With Neurocognitive Sequelae
Survivors of childhood cancer are at risk for developing neurocognitive sequelae. Multiple meta-analyses demonstrate significant deficits in overall intellectual abilities, academic functioning and specific cognitive skills among…
- Conditions
- Childhood Non-Hodgkin Lymphoma, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia
- Trial name
- NCT04541056
- Testing
- Goal Management Training (GMT), Brain Health Workshop (BHW)
- Where
- 3 sites in Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Pediatric Cancer, Pediatric ALL
Feasibility/Acceptability of Attentional-Control Training in Survivors
This is a multicenter pilot randomized controlled trial, with an active control condition, of the feasibility, acceptability, and preliminary efficacy of EndeavorRx in a cohort of survivors of acute lymphoblastic leukemia or…
- Conditions
- Pediatric Cancer, Pediatric ALL, Pediatric Brain Tumor, Attention Difficulties
- Trial name
- FAACTS (NCT05528939)
- Testing
- EndeavorRx, Control video game
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's National Research Institute
Childhood Cancer Survivors
Overnight Fasting After Completion of Therapy: The OnFACT Study
The purpose of this study is to test whether regularly not eating for at least 14 hours overnight ("intermittent fasting") is feasible and can improve blood sugar.
- Trial name
- NCT03523377
- Testing
- prolonged overnight fasting, usual care
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Frailty, Childhood Cancer
An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer
This is a first-in survivor pilot study with the goal of establishing preliminary evidence of efficacy, safety, and tolerability of two senolytic regimens to reduce markers of cellular senescence (primary outcome: p16^INK4a) and…
- Trial name
- NCT04733534
- Testing
- Dasatinib plus Quercetin, Fisetin
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- St. Jude Children's Research Hospital
Childhood Cancer, Late Effects
Young Survivors at Kantonsspital Aarau, Switzerland
The Young Survivors at Kantonsspital Aarau project assesses the prevalence and severity of late effects in survivors of childhood and adolescent cancer according to the modified CTCAE criteria prospectively.
- Trial name
- NCT04811794
- Testing
- Physical examination, diagnostic tests, laboratory tests, Personal history
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Kantonsspital Aarau
Childhood Cancer Survivors, Fertility
Fertility and Ovarian Reserve in Female Childhood Cancer Survivors
Ovarian function impairment affects the quality of life of the survivors of paediatric cancer by impacting fertility, bone quality and mental and cognitive health.
- Conditions
- Childhood Cancer Survivors, Fertility, Ovarian Reserve, CED
- Trial name
- PRINCESS (NCT06626282)
- Where
- 3 sites in Belgium
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Chemotherapy Effect, Dental Caries
Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10
To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors.
- Conditions
- Chemotherapy Effect, Dental Caries, Malocclusion, Childhood Cancer
- Trial name
- NCT06517927
- Testing
- Clinical and radiographic dental examination
- Where
- Belgium
- Volunteers
- 142 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cancer, Glioma
Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
Advances in medical care have significantly improved survival among children with cancer. In China, the 5-year survival rate has reached 71.9%.
- Conditions
- Cancer, Glioma, Leukemia (Both ALL and AML)
- Trial name
- SC-Het-GM-CCS (NCT07450872)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Pediatric Cancer Survivor, Survivorship
Digital Self-Management and Peer Mentoring Intervention
This study tests how helpful a digital self-management and peer mentoring program is to young adult survivors of childhood cancer to improve their ability to manage their survivorship care as they transition from pediatric to…
- Conditions
- Pediatric Cancer Survivor, Survivorship, Cancer
- Trial name
- NCT06763770
- Testing
- Managing Your Health (MYH), The Usual Care + Educational Control
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Rutgers, The State University of New Jersey