Clinical trials: Survivorship, active
Cancer
Real-World Study of Young Patients With Solid Tumors in China
To evaluate organ preservation rates, fertility preservation, and long-term quality of life after treatment among young patients.
- Trial name
- NCT07708935
- Testing
- Ages 18-40
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- Fudan University
Clinicopathologic Characters of Renal Cell Carcinoma in Young Patients
Clinicopathological Features of Renal Cell Carcinoma in Young Patients
Analysis of Clinicopathologic Characters of Renal Cell Carcinoma in Young Patients and their influence on the survival outcomes
- Trial name
- NCT06730997
- Volunteers
- 100 people
- Sponsor
- Assiut University
Neoplasms
Evaluation of a Program for Routine Implementation of Symptom Distress Screening and Referral in Cancer Care
This study proposes to evaluate the process and outcome of an implementation program designed to implement nurse-led symptom distress screening and referral into routine cancer care clinics.
- Trial name
- NCT05949996
- Testing
- A nurse-led symptom distress screening program
- Where
- 10 sites in Hong Kong
- Volunteers
- 2,885 people
- Sponsor
- The University of Hong Kong
Critical Illness, Recovery Outcomes
Improving Survivorship for Critically Ill Patients Aged 65 and Over
IMPROVE-65 is a randomised control trial designed specifically for people aged over 65 who have survived critical illness. It aims to support patients and general practitioners by providing timely, personalised information to…
- Conditions
- Critical Illness, Recovery Outcomes, Care Coordination
- Trial name
- IMPROVE-65 (NCT07175961)
- Testing
- Multicomponent telehealth care coordination
- Where
- 2 sites in Australia
- Volunteers
- 300 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Cancer Survivorship
Cooperative Extension and Cancer Survivorship
The goal of this clinical trial is to learn if a cancer survivor program, delivered via Cooperative Extension, is feasible and if it can improve health outcomes in cancer survivors who are post-active treatment.
- Trial name
- SUCCESS (NCT06869512)
- Testing
- SUCCESS
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Oklahoma
Breast Cancer Survivor, Colorectal Cancer Survivors
Testing the Feasibility of a Virtual Application to Support Breast and Colorectal Cancer Survivors
The goal of this study is to determine the feasibility of implementing a mobile health application for breast and colorectal cancer survivors following primary treatment.
- Trial name
- NCT07312786
- Testing
- virtual self-management intervention
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Nova Scotia Health Authority
Nasopharyngeal Carcinoma, Metastasis
An Open-label, Multicentre, Phase II/III RCT of PFLL Versus GP Combined With JS001 as the First-line Therapy for mNPC
The treatment of distant metastasis is a key challenge for nasopharyngeal carcinoma because of poor outcomes, among which, chemotherapy is the cornerstone.
- Conditions
- Nasopharyngeal Carcinoma, Metastasis, Chemotherapy, Immunotherapy
- Trial name
- NCT04890522
- Testing
- Triprilimab(JS001), Cisplatin, 5-Fluorouracil
- Where
- China
- Volunteers
- 622 people
- Sponsor
- Sun Yat-sen University
Primary Cutaneous Lymphoma
TreAtments and outComes in paTients With prImary CutAneous Lymphoma
In order to further improve the diagnosis and treatment level of primary cutaneous lymphoma in China, the National Clinical Center for Skin and Immune Diseases established a standardized diagnosis and treatment center for primary…
- Trial name
- TACTICAL (NCT05518851)
- Where
- 5 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Peking University First Hospital
Neoplasms, Cancer Survivorship
Effectiveness of a Guided, Web-based, Stepped-care-approach to Cognitive Behavioral Therapy for Insomnia in Cancer Survivors
The goal of this multicenter randomized clinical trial is to develop and evaluate a web-based stepped-care approach to Cognitive Behavioral Therapy for Insomnia (CBT-I), specifically tailored to adult cancer survivors…
- Conditions
- Neoplasms, Cancer Survivorship, Insomnia
- Trial name
- eNightfall (NCT07876661)
- Testing
- Stepped-care Cognitive Behavioral Therapy for Insomnia, Standard web-based Cognitive Behavioral Therapy for Insomnia, Control arm - Care as usual with sleep hygiene leaflet
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- Vrije Universiteit Brussel
Colon Cancer, Adjuvant Therapy
A Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients
The purpose of this study is to determine whether acetylsalicylic acidis effective on the recurrence and survival of colon cancer patients.
- Trial name
- ASPIRIN (NCT02301286)
- Testing
- Acetylsalicylic acid
- Where
- 32 sites in Netherlands
- Volunteers
- 770 people
- Sponsor
- Leiden University
Neuroendocrine Carcinoma of Lung, Neuroendocrine Carcinoma of Thymus
CompArative Analysis Between, Thymic, pulmonaRy and Pancreatic Well Differentiated High Grade Neuroendocrine Tumors
The study involves the enrollment of 34 patients diagnosed with advanced thymic, pulmonary and duodeno-pancreatic well-differentiated high grade neuroendocrine tumors (Ki-67 > 20%).
- Trial name
- LINEAR (NCT07429851)
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- European Institute of Oncology
ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Diabetes Mellitus
Abnormal Glucose Tolerance in Allogeneic Hematopoietic Stem Cell Transplantation
To investigate the impact of abnormal glucose tolerance in hematopoietic stem cell transplantation donors on patients' post-transplant survival outcomes.
- Conditions
- ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Diabetes Mellitus, Impaired Fasting Glucose
- Trial name
- NCT06704542
- Where
- 6 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Ruijin Hospital
Breast Cancer, Breast Cancer Female
Effectiveness of Personalized Surveillance and Aftercare for Breast Cancer
Surveillance and aftercare for curatively treated primary breast cancer patients is currently mostly 'one-size-fits-all', but can be personalized based on patients' risk of recurrence (depending on patient-, tumor- and…
- Conditions
- Breast Cancer, Breast Cancer Female, Survivorship
- Trial name
- NABOR (NCT05975437)
- Testing
- personalized surveillance plans (PSP) and personalized aftercare plans (PAP)
- Where
- 10 sites in Netherlands
- Volunteers
- 1,040 people
- Sponsor
- Comprehensive Cancer Centre The Netherlands
Periapical Diseases, Bioceramic Sealers
Survival and Success of Two Different Filling Techniques
This randomized clinical study analysed the clinical use of a new bioceramic premixed CaSi-containing sealer in association with a warm carrier-based technique or a traditional epoxy resin based sealer.
- Conditions
- Periapical Diseases, Bioceramic Sealers, Survival Rate, Healing Rate
- Trial name
- ROOTCANAL (NCT06252337)
- Testing
- bioceramic sealer group
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Acute Promyelocytic Leukemia (APL)
Oral Arsenic With ATRA for Newly Diagnosed Patients With Acute Promyelocytic Leukemia
It is a non-randomized, multicenter, prospective study, aiming to treat patients with newly diagnosed acute promyelocytic leukemia with a combination of oral arsenic and atra, with low dose chemotherapy for those with high-risk…
- Trial name
- IC-APL2020 (NCT06982274)
- Testing
- Realgar-Indigo Naturalis Formulation
- Where
- Brazil
- Volunteers
- 115 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Cardiac Arrest, Pediatric ALL
Pediatric In-Hospital Cardiac Arrest International Registry (PACHIN)
: An intrahospital CA data recording protocol has been designed following the Utstein model. Database is hosted according to European legislation regarding patient data protection. It is drafted in English and Spanish.
- Conditions
- Cardiac Arrest, Pediatric ALL, In-hospital Cardiac Arrest
- Trial name
- PACHIN (NCT04675918)
- Testing
- Cardiac arrest
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Jimena del Castillo
Colorectal Cancer
A Comparative Study Between Early Onset Colorectal Cancer and Late Onset Colorectal Cancer Patients
This study aims to investigate the clinical, socioeconomic, behavioral, genetic, and molecular factors characterizing Early Onset Colorectal Cancer (EOCRC) patients compared with Late Onset Colorectal Cancer (LOCRC) patients
- Trial name
- EOrOS (NCT06326879)
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 340 people
- Sponsor
- Istituto Clinico Humanitas
Diabetes Mellitus, Pancreas Transplantation
The Norwegian Pancreas Transplantation (PTx) Study
Several studies have shown acceptable results after Pancreas Transplantation (PTx) by substituting ATG with basiliximab, which is considered to convey a considerably lower number of adverse events.
- Conditions
- Diabetes Mellitus, Pancreas Transplantation, Allograft Rejection, Surgical Complication Nec
- Trial name
- PTx (NCT01957696)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Colorectal Cancer
Clinical Outcomes of Treatment With Immunomodulator Plus Cancer Therapies for Patients With Colorectal Cancer
This study aims to evaluate the survival and treatment outcomes among colorectal cancer patients undergoing anti-cancer treatment, both with and without an immunomodulator.
- Trial name
- NCT06557668
- Where
- 2 sites in Taiwan
- Volunteers
- 250 people
- Sponsor
- Taichung Veterans General Hospital
Neuroendocrine (NE) Tumors
Survival Without Persistent Limiting Toxicity: Real Life Prospective Cohort of Advanced Neuroendocrine Tumor
Advanced neuroendocrine tumors (NETs) are rare cancers, characterized by prolonged survival (median>5 years). If five medical options are now approved and 4 others are only recommended, the best sequence is still unknown.
- Trial name
- TOLERATE (NCT07471425)
- Testing
- quality of life questionnaire, treatment side effect follow up
- Where
- 14 sites in France
- Volunteers
- 1,100 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris