Clinical trials: Suspect Glaucoma
Glaucoma
Anterior Chamber Angle Examination in Angle Closure Suspect Patients
The aim of this study is to detect PACG suspects using both AS OCT and Scheimpflug imaging.
- Trial name
- NCT05209204
- Testing
- ASOCT, Pentacam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Ocular Hypertension, Glaucoma
Effects of a Single OMT on Intraocular Pressure (IOP) in Ocular Hypertenive or Glaucoma Suspect Subjects
The hypothesis is that osteopathic manipulative treatment (OMT)will significantly reduce intraocular pressure (IOP) in individuals with ocular hypertension (OHT) and glaucoma suspect patients.
- Trial name
- OMT4OHT (NCT01864642)
- Testing
- osteopathic manipulative treatment (OMT)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wisconsin, Madison
Ocular Hypertension, Suspect Glaucoma
Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects
The goal of this clinical trial is to compare participants treated with latanoprost to those treated with Rocklatan (netarsudil/latanoprost) to determine whether the addition of netarsudil results in greater improvements in…
- Trial name
- NCT04401982
- Testing
- Rocklatan (Netarsudil 0.02%/ latanoprost 0.005), Latanoprost (0.005%)
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Glaucoma, Intraocular Pressure
Accuracy of Handheld and Non-contact Tonometry
Monitoring the intraocular pressure (IOP) is one of the most important tests used in follow-up among glaucoma suspects and confirmed glaucomatous patients.
- Conditions
- Glaucoma, Intraocular Pressure, Glaucoma, Suspect
- Trial name
- NCT05352906
- Testing
- Intraocular pressure
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Benha University
Glaucoma, Glaucoma Suspect
Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study
The goal is to conduct a 5-year prospective, randomized controlled trial to test an innovative, community-based intervention using posterior and anterior fundus photography of the optic nerve and macula and intraocular eye…
- Conditions
- Glaucoma, Glaucoma Suspect, Diabetic Retinopathy, Ocular Hypertension
- Trial name
- NCT02390245
- Testing
- Free Eye Screenings, Enhanced Intervention, Usual Care
- Where
- United States
- Volunteers
- 906 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Glaucoma, Hypertension
Know Your Pressures NYC
Dr. Lisa A. Hark (PI and Study Chair) and an interdisciplinary team have designed "Know Your Pressures NYC" to conduct blood pressure (BP)/glaucoma screenings in adults age 40+ to identify undiagnosed and/or uncontrolled…
- Conditions
- Glaucoma, Hypertension, Glaucoma, Suspect, Elevated Blood Pressure
- Trial name
- NCT05992415
- Testing
- Virtual Automated Navigator Intervention with Health Education, Usual Care
- Where
- United States
- Volunteers
- 7,085 people, healthy volunteers welcome
- Sponsor
- Columbia University
Diabetic Retinopathy, Age Related Macular Degeneration
AI-Assisted Detection of Posterior Segment Diseases: DR, AMD, RVO, and Glaucoma
The purpose of this multi-center study is to evaluate the extent to which AI-assisted fundus image interpretation improves the diagnostic performance of ophthalmologists.
- Conditions
- Diabetic Retinopathy, Age Related Macular Degeneration, Retinal Vein Occlusion, Glaucoma
- Trial name
- NCT07318428
- Testing
- VUNO Med-Fundus AI
- Where
- 5 sites in South Korea
- Volunteers
- 10 people
- Sponsor
- Inje University
Glaucoma, Glaucoma, Suspect
Reliability and Reproducibility of the Eye Check Tonometer
To investigate whether the new applanation tonometer (EyeCheck monitor) can provide intraocular pressure (IOP) measurements comparable to those of traditional tonometers such as the Goldmann applanation tonometer and the Tonopen.
- Trial name
- EyeCheck (NCT04639947)
- Testing
- EyeCheck, Traditional Tonometer (Goldmann and Tonopen)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Duke University
Glaucoma
Glaucoma Laser Assessment of Stability and Sustainability
The GLASS Study is designed to help researchers learn whether repeating a non-invasive laser treatment called DSLT (Direct Selective Laser Trabeculoplasty) can better control eye pressure in patients with early-stage glaucoma or…
- Trial name
- GLASS (NCT06963684)
- Testing
- Dual-Treatment Direct Selective Laser Trabeculoplasty (DSLT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Twin Cities Eye Consultants
Glaucoma, Macular Degeneration
BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases
The purpose of this research study is to better understand the impact of visual impairment caused by different eye diseases on the ability to perform daily activities and compare it to that in patients without eye diseases.
- Conditions
- Glaucoma, Macular Degeneration, Glaucoma Suspect, Optic Neuropathy
- Trial name
- NCT03318549
- Testing
- Visual Performance tests, Brain-computer interface
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma, Suspect, Diabetic Retinopathy
Eye Health Intervention Study in Upper Manhattan
Individuals living in Upper Manhattan have limited access to eye care, high vision impairment rates, and poor ocular health outcomes.
- Conditions
- Glaucoma, Suspect, Diabetic Retinopathy, Cataract, Refractive Errors
- Trial name
- EYES-UM (NCT06112431)
- Testing
- Intervention, Usual Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Glaucoma, Ocular Hypertension
Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers
The goal of this clinical trial is to learn if implementation of an eye screening program at Federally Qualified Health Center (FQHC) clinics provides results that participants may have glaucoma, and/or other eye conditions…
- Trial name
- AI-RONA (NCT06629649)
- Testing
- Glaucoma screening using an AI-algorithm and screening for diabetic retinopathy, cataract, and visual acuity impairment.
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- University of Alabama at Birmingham
Open-angle Glaucoma
Dose, Effects and Characteristics of Pilocarpine
The purpose of this investigation, in which pilocarpine was given in repeated doses, was to evaluate: Part I - the effects of different concentrations of pilocarpine hydrochloride on intraocular pressure.
- Trial name
- NCT00803803
- Testing
- Pilocarpine Concentration, Pilocarpine Frequency
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Wills Eye
Ocular Hypertension
Study of ST266 Given by Intranasal Delivery in Glaucoma Suspect Subjects
The primary objective of this trial is to assess the safety of ST266 given by non-invasive intranasal trans-cribriform delivery to glaucoma suspect subjects with ocular hypertension, optic nerve cupping, or family history of…
- Trial name
- NCT03901781
- Testing
- ST266 via Intranasal Delivery
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Glaucoma, Ocular Hypertension
A Phase I Clinical Trial of DARC
Glaucoma is a major cause of irreversible blindness worldwide, caused by retinal nerve cell (RGC) death. This is currently identified only after significant vision loss has already occurred with an early event in, and a potential…
- Conditions
- Glaucoma, Ocular Hypertension, Glaucoma, Suspect
- Trial name
- NCT02394613
- Testing
- ANX776
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University College, London
Glaucoma, Suspect, High Myopia
Effect of Lowering IOP in Glaucoma Suspects With HM
Currently, whether and when intraocular pressure (IOP) lowering medication should be used in glaucoma suspects with high myopia (HM) is still a dilemma.
- Trial name
- GSHM (NCT04296916)
- Testing
- IOP lowering eye drops
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sun Yat-sen University
Primary Angle Glaucoma Closure Suspect
Superior vs Temporal Laser Peripheral Iridotomy in Primary Angle Closure Suspects (PACS)
Basic Study Design: Prospective, randomized, single-center, single-blinded study to compare dysphotopsias and pain recollection immediately 2 weeks, and 3 months after LPI in PACS patients who have a clear indication for…
- Trial name
- NCT04741919
- Testing
- Yag Laser peripheral Iridotomy
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Glaucoma
SENSIMED Triggerfish Safety and Tolerability
The purpose of this investigation is to study the safety and tolerability of SENSIMED Triggerfish, a soft contact lens-based device intended to continuously record relative changes in intraocular pressure (IOP).
- Trial name
- NCT01319617
- Testing
- SENSIMED Triggerfish
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Sensimed AG
Glaucoma, Suspect, Glaucoma
Validation of an Automatic Analysis Algorithm of the Probability of Glaucoma From Optic Disc Images
Clinical, cross-sectional and prospective study to assess the images of the posterior pole of the retina of patients from the Glaucoma Unit of the IOBA and the Hospital Clínico Universitario de Valladolid during the period…
- Conditions
- Glaucoma, Suspect, Glaucoma, Ocular Hypertension
- Trial name
- NCT04972695
- Testing
- Fundus Photographs (retinographies)
- Where
- Spain
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Glaucoma, Glaucoma, Suspect
Automated Applanation Tonometry - Updated
Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability.
- Trial name
- NCT07298356
- Testing
- Standard GAT, Fixed force GAT, Upright applanating prototype
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University