Clinical trials: Sweat
Cystic Fibrosis
Sweat Evaporimeter Measurement
The investigators hypothesize that measurement of beta adrenergic induced sweat rate using an evaporimeter can accurately and reliably determine different levels of CFTR dysfunction within a spectrum of patients expressing…
- Trial name
- NCT01708655
- Testing
- Sweat Evaporimeter measurement
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sweat Rate
Normative Data for Sweating Rate, Sweat Sodium Concentration and Sweat Sodium Loss in Female Athlete
The main objectives are to determine sweat sodium concentration [Na+], whole body sweat rate (WBSR) and rate of sweat sodium loss (RSSL) in female athletes aged 13 and above during their normal planned training session across…
- Trial name
- NCT06995768
- Testing
- Sweat patch
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Heat Cramps, Heat Rash
Testing Interventions to Mitigate the Health Impact of Heatwaves on Primary School Children in Climate-vulnerable Districts of Bangladesh.
The goal of this clinical trial is to assess the impact of implementing a combination of heat education and school-based physical infrastructure interventions in reducing heat related illnesses and improving educational outcomes…
- Conditions
- Heat Cramps, Heat Rash, Heat Exhaustion, Heat Stress
- Trial name
- NCT07877935
- Testing
- Solar reflective paint, Bamboo ceiling with polyethylene foam, Heat education toolkit
- Where
- 2 sites in Bangladesh
- Volunteers
- 2,875 people, healthy volunteers welcome
- Sponsor
- BRAC University
Hyperhidrosis, Axillary Hyperhidrosis
miraDry Post Market Tumescent Anesthesia Study
This clinical trial will collect data on the safety and efficacy of the miraDry treatment when High Volume Anesthesia (Tumescent Anesthesia) is used as an alternate method of anesthetizing the axilla prior to the miraDry System…
- Trial name
- NCT05546710
- Testing
- miraDry treatment
- Volunteers
- healthy volunteers welcome
- Sponsor
- miraDry, Inc.
XLHED
A Cross-Sectional Natural History Study to Evaluate Sweat Volume and Other Phenotypic and Genetic Characteristics in Patients Affected by XLHED
The proposed natural history study will enroll male patients with a diagnosis of XLHED, female carriers of XLHED and healthy volunteers.
- Trial name
- NCT03912792
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dermelix Biotherapeutics, LLC.
Sweat, Underarm Odor
Study to Evaluate the Efficacy of Bite's Natural Deodorant
This is an open-label observational single-arm clinical trial to study the efficacy of a commercial deodorant and its effect on odor, clothing (stains), and quality of life.
- Trial name
- NCT05503784
- Testing
- BITE Deodorant
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kind Lab PBC.
Hidradenitis Suppurativa
Defects of Keratinocytes Function in Dermatologic Patients
NOTCH signaling in the skin exerts a pivotal role in the regulation of normal keratinocytes turnover by mediating the balance between proliferation, differentiation, apoptosis and autophagic flux progression.
- Trial name
- NCT06324552
- Where
- 15 sites in Austria, Belgium and 4 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Burlo Garofolo
Scar, Hidradenitis Suppurativa
Fractional CO2 Laser Fenestration and Steroid Delivery in HS Lesions
Assess the efficacy of fractional ablative CO2 therapy combined with topical steroids in HS patients with Hurley stage I or stage II disease.
- Trial name
- NCT05580029
- Testing
- Triamcinolone Topical, Fractional Ablative CO2 Therapy, EMLA 5% cream
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Southern California
HİDRADENİTİS SUPPURATİVA
Periodontal Status and Disease Severity in Hidradenitis Suppurativa Patients
This cross-sectional study aims to evaluate the periodontal status of individuals diagnosed with hidradenitis suppurativa (HS) and to compare them with systemically healthy controls.
- Trial name
- NCT07294456
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Fluid Intake in Athletes, Sweating Rate in Athletes
Validity of Smart Cap and Smart Sweat Patch
The main objectives are to determine the validity of a Smart Cap in measuring fluid intake during running and fitness exercise and the validity of a Smart Sweat Patch in measuring sweat rate and sweat chloride concentration…
- Conditions
- Fluid Intake in Athletes, Sweating Rate in Athletes, Sweat Chloride Concentration in Athletes
- Trial name
- NCT04920266
- Testing
- Smart Cap, running and fitness exercisers only, Sweat Patch, all subjects- running, fitness, cycling, Reference sweat patch, all subjects - running, fitness, cycling
- Where
- 3 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Hidradenitis Suppurativa
Treatment of Hidradenitis Suppurativa With Eth 755nm Alexandrite Laser
Patients with bilateral hidradenitis in the axilla, groin and/or inframammary will be treated on one side with the Alexandrite hair removal laser. The other side will serve as the control.
- Trial name
- NCT03054155
- Testing
- Alexandrite Laser
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Palmar Hyperhidrosis, Hyperhidrosis
An Open Label Study for Palmar Hyperhydrosis
The purpose of this open-label study is to evaluate the efficacy and safety of different methods of application of glycopyrronium cloth, 2.4% in patients with palmar hyperhidrosis
- Conditions
- Palmar Hyperhidrosis, Hyperhidrosis, Sweat Gland Diseases, Skin Diseases
- Trial name
- NCT04906655
- Testing
- Glycopyrronium 2.4 % Medicated Cloth
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pariser, Robert J., M.D.
Sweat Rate, Heat Effect
Time Onset Sweat Sodium (TOSS) Study
Prior to each trial, you will be provided with urine jugs and food/fluid logs to record food and drink intake for 24hr. You will be asked to log food/fluid intake 24hr leading into trials.
- Conditions
- Sweat Rate, Heat Effect, Sweat Sodium Concentration
- Trial name
- TOSS (NCT07464743)
- Testing
- Exercise in the heat
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Hidradenitis Suppurativa (HS)
Exploration of Brain Functional Networks in Patients With Hidradenitis Suppurativa Using fMRI
The goal of this observational study is to learn whether adults with hidradenitis suppurativa (HS) have changes in resting brain activity and how these changes are related to disease severity, pain, sleep, mood, and quality of…
- Trial name
- NCT07755670
- Testing
- Routine Biologic Therapy for Hidradenitis Suppurativa
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Hidradenitis Suppurativa, Healthy Volunteers
Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin
This research is being done to assess the effect of radiofrequency (RF)-based treatment on skin and skin conditions.
- Trial name
- NCT05066113
- Testing
- Radiofrequency-Based treatment
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
MSCs
MSCs Source of Sweat Gland Cells of Large Area Skin Injury Patients Transplant of the Wound
The main purpose of this test is to assess the umbilical cord mesenchymal stem cells (MSCs) UC between source sample sweat gland cells wound transplanted effectiveness and safety for the treatment of large area skin lesions of…
- Trial name
- MSCs (NCT02669199)
- Testing
- MSCs
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Heat Illness, Allergic Rhinitis
Over-the-Counter Antihistamines & Heat Stress
Allergic rhinitis (AR) currently affects ~25% of Canadians, and due to factors of climate change, this number is expected to increase over the coming decade.
- Conditions
- Heat Illness, Allergic Rhinitis, Heat Injury, Sudomotor Sympathetic Dysfunction
- Trial name
- NCT06217367
- Testing
- 50 mg Diphenhydramine, 10 mg Loratadine, 5 mg Desloratadine
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Hyperhidrosis Primary Focal Palms
Compensatory Sweating After Unilateral Sympathectomy on the Dominant Side or Bilateral Sequential Sympathectomy
The standard treatment for palmar hyperhidrosis is bilateral sequential thoracic sympathectomy. High rates of compensatory sweating due to the surgical procedure are described in the literature.
- Trial name
- Universusbi (NCT03921320)
- Testing
- Bilateral sequential sympathectomy, Unilateral sympathectomy, Contralateral sympathectomy
- Where
- 10 sites in Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Kidney Diseases
Measurement of Sweat Sodium Concentration in Patients With Chronic Kidney Disease
It has been shown that excretion of sodium and water through the skin in the form of sweat represents a regulatory mechanism of electrolyte- and fluid balance.
- Trial name
- NCT06354842
- Testing
- pilocarpine iontopheresis
- Where
- Austria
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Atopic Dermatitis, Psoriasis
Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases
Chronic inflammatory skin diseases constitute a heterogeneous group of pathologies. They affect the skin but also other organs (joints, lungs, muscles, etc.). Their prognosis and response to treatments is extremely variable.
- Conditions
- Atopic Dermatitis, Psoriasis, Hidradenitis Suppurativa, Lichen Planus
- Trial name
- ImmuneSkinBank (NCT06599411)
- Testing
- Sampling
- Where
- France
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris