Clinical trials: Sweat
Cystic Fibrosis
Safety Study of Orally Administered Curcuminoids in Adult Subjects With Cystic Fibrosis
The purpose of this study is to assess the safety of advancing doses of curcuminoids administered orally for fourteen consecutive days in adult subjects with cystic fibrosis (CF) who are homozygous for ΔF508 CFTR.
- Trial name
- SEER (NCT00219882)
- Testing
- standardized turmeric root extract
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Ramsey, Bonnie, MD
Hidradenitis Suppurativa
MABp1 IN HIDRADENITIS SUPPURATIVA REFRACTORY TO ADALIMUMAB
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder. Although adalimumab is recently licensed for moderate to severe HS, many cases fail to respond or relapse during treatment.
- Trial name
- NCT02643654
- Testing
- MABp1
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Evangelos J. Giamarellos-Bourboulis, M.D.
Menopause
Getting Under the Skin of the Menopausal Hot Flush
The aim of this research is to 1) test how the skin blood vessels and sweat glands function in women who experience hot flushes by using skin microdialysis to deliver small amounts of substances to the skin that cause increased…
- Trial name
- NCT06222073
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Hidradenitis Suppurativa, Acne Inversa
Intense Pulsed Light Therapy for Hidrosadenitis Suppurativa
6 monthly treatments with IPL laser in patients with Hidradenitis Suppurativa. The effect in measured on several severity scores.
- Trial name
- NCT03203122
- Testing
- IPL laser
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Zealand University Hospital
Hidradenitis Suppurativa
Treatment of Hidradenitis Suppurativa Using Etanercept
Therapy with etanercept, a TNF inhibitor will reverse the inflammation, symptoms and quality of life and allow healing of HS.
- Trial name
- NCT00949546
- Testing
- etanercept
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Penn State University
Acne, Atopic Dermatitis
Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.
- Conditions
- Acne, Atopic Dermatitis, Chronic Hand Eczema, Hidradenitis Suppurativa
- Trial name
- NCT05994976
- Testing
- Blood samples collection, Oral samples collection, Hair samples collection
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Hidradenitis Suppurativa
A Randomized, Controlled Trial Comparing the Use of a Biodegradable Temporizing Matrix to Cadaver Skin in the Reconstruction of Hidradenitis Suppurativa Excisions
This will be a prospective, interventional, single-center, randomized, controlled, comparative study comparing a total of 10 patients treated with BTM and SOC in wounds diagnosed with Hidradenitis suppurativa (5 in each group).
- Trial name
- NCT05477225
- Testing
- NovoSorb® BTM, Human Cadaveric Allograft
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Joseph M. Still Research Foundation, Inc.
Alcohol Consumption, Heat Stress
Ethanol Consumption in the Heat
Climate change has significantly increased the earth's average surface temperature and heat waves have been predicted to increase in frequency, intensity and duration.
- Conditions
- Alcohol Consumption, Heat Stress, Age
- Trial name
- NCT06935045
- Testing
- Alcohol (Ethanol)
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Diphenhydramine Causing Adverse Effects in Therapeutic Use, Hyperthermia
Diphenhydramine and Sweating
In 2012, it was estimated that nearly 1 in 4 Canadians suffer from allergic rhinitis. To add, 78% of individuals working in predisposing environments are predicted to develop occupational rhinitis.
- Conditions
- Diphenhydramine Causing Adverse Effects in Therapeutic Use, Hyperthermia, Allergic Rhinitis, Sweating
- Trial name
- BENEXE2022 (NCT05586477)
- Testing
- Diphenhydramine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Hidradenitis Suppurativa
Hidradenitis Suppurativa (HS) Tunneling Wounds
The purpose of this study is to look at the change in the microbiome (bacterial composition) of an HS tunneling wound and examine if treatment with an antibiofilm surfactant wound gel (ABWG) (a topical medication that will fight…
- Trial name
- NCT04648631
- Testing
- antibiofilm surfactant wound gel (ABWG)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Miami
Hidradenitis Suppurativa, Quality of Life
Impact of Hidradenitis Suppurativa on Quality of Life Functions
The goal of this study is to get a better understanding of the impact of Hidradenitis Suppurativa (HS) on the quality of life of patients with this condition.
- Trial name
- NCT03288337
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Montefiore Medical Center
Healthy Adults
Sweat Sensors for Athletic Performance
Pilot study of a soft, flexible wearable sweat sensor
- Trial name
- NCT03566381
- Testing
- Application of a soft patch composed of medical-grade silicone that collects sweat during a subject's natural behaviors.
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cystic Fibrosis
A Study of Sweat Testing Using a Quantitative Patch
The primary aim of the study is to determine if the CF Quantum Sweat Test provides sweat chloride results that are equivalent to the results from traditional sweat testing.
- Trial name
- NCT01345617
- Where
- 3 sites in United States
- Volunteers
- 170 people
- Sponsor
- Polychrome Medical, Inc.
Acute Kidney Failure, Chronic Kidney Diseases
Enhancing Fluid Transfer Through the Skin, by Increased Sweat Rate, on Hemodialysis Patients
To demonstrate safety and performance of AquaPass System for improving fluid balance in hemo-dialysis patients, by increasing fluid loss via the skin.
- Trial name
- NCT06358365
- Testing
- The AquaPass System
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- AquaPass Medical Ltd.
Hidradenitis Suppurativa
This Was a Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS).
The purpose of this study was to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week…
- Trial name
- SUNSHINE (NCT03713619)
- Testing
- secukinumab
- Where
- 111 sites in United States, Argentina and 27 more
- Volunteers
- 544 people
- Sponsor
- Novartis Pharmaceuticals
Hidradenitis
Proof-of-concept Study Evaluating Subcutaneous Amlitelimab in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
This is a parallel, Phase 2, 2-arm, double-blind, randomized, multicenter, multinational, placebo-controlled study to evaluate efficacy, safety, pharmacokinetics (PK), and biological effects of treatment of subcutaneous injection…
- Trial name
- NCT06118099
- Testing
- Amlitelimab
- Where
- 42 sites in United States, Australia and 9 more
- Volunteers
- 90 people
- Sponsor
- Sanofi
Menopause
Qing'E Formula Therapy on Menopausal Symptoms
The objective of this study is to evaluate whether a Chinese medicine formula (Qing'E) is effective in alleviating menopausal symptoms and safety.
- Trial name
- NCT01805765
- Testing
- Qing'E pills
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Hyperhidrosis, Residual Limbs
Antiperspirant in the Treatment of Residual Limp Hyperhidrosis for Prosthetic Users
The aim of the present pilot study is to evaluate the effect of antiperspirant to treat residual limb hyperhidrosis with the emphasis on the utility of the iodine-starch test to identify the location of the sweating.
- Trial name
- NCT05501444
- Testing
- Topical antiperspirant
- Where
- Norway
- Volunteers
- 7 people
- Sponsor
- Sophies Minde Ortopedi
Autoimmune Diseases, Inflammatory Bowel Diseases
Chronic Inflammatory Disease, Lifestyle and Treatment Response
Chronic inflammatory diseases (CID) - including inflammatory bowel diseases (Crohn's disease and ulcerative colitis), rheumatic conditions (rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis), inflammatory skin…
- Conditions
- Autoimmune Diseases, Inflammatory Bowel Diseases, Crohn Disease (CD), Colitis, Ulcerative (UC)
- Trial name
- BELIEVE (NCT03173144)
- Testing
- Primary exposure variable, Other (exploratory) exposure variables
- Where
- 3 sites in Denmark
- Volunteers
- 233 people
- Sponsor
- University of Southern Denmark
Hidradenitis Suppurativa
Anakinra as a Treatment for Hydradenitis Suppurativa
This is an open-label, proof-of-concept research study to assess the effectiveness of anakinra in the treatment of patients with hidradenitis suppurativa (HS).
- Trial name
- NCT01516749
- Testing
- anakinra
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, San Francisco